Registered Nurse Jobs in Kentucky
Registered Nurse jobs in Kentucky are concentrated in Louisville, Lexington, and Bowling Green, where large health systems like Norton Healthcare, UK HealthCare, and Baptist Health maintain consistent hiring across med-surg, critical care, and emergency departments. Demand runs from new graduates entering residency programs to experienced charge nurses and nurse managers. Openings in behavioral health and long-term care have grown alongside Kentucky's expanding rural health initiatives. Scan the live roles below and apply to whichever ones fit.
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We are committed to advancing person-directed care and quality outcomes. Many of our facilities continue to receive high performance ratings and accreditations. As an award-winning organization recognized over the years by national outlets such as U.S. News & World Report, we take pride in fostering compassionate care environments and being an employer of choice in the healthcare industry.
FULL TIME NIGHT SHIFT UNIT MANAGER / NURSE SUPERVISOR
RN / LPN
WILL WORK MONDAY - THURSDAY 7P-7A
How you Will make a Difference:- Registered Nurse with current state license.
- One (1) to three (3) years of related experience; supervisory experience preferred.
- Must have a current / active CPR certification.
- Medical, Dental & Vision Coverage
- First Stop Health Virtual Healthcare
- 401(k) & Roth 401(k)
- Company-Paid & Voluntary Life Insurance
- Health Savings Account (HSA) & Flexible Spending Account (FSA)
- Paid Time Off (PTO) & Holiday Incentive Pay
- Tuition Reimbursement & Tuition Discounts with Select Universities
- Student Debt Assistance (eligible SNF RNs & LPNs)
- Uniform Allowance
- Partner Perks Discount Program
- Perfect Attendance Program
- Pay Advance & Next Day Pay
- Employee Assistance Program (EAP)
- Support Beyond Benefits with VitalLink and the Signature Inspire Foundation
At Signature HealthCARE, our team members are empowered—not just encouraged—to use their talents and abilities to solve problems.
Our culture is built on three pillars: Learning, Spirituality, and Intra-preneurship.
Each pillar has dedicated initiatives that strengthen our culture and create opportunities for growth.
Come see what the revolution is all about!
Signature HealthCARE is an Equal Opportunity/Affirmative Action Employer. We are committed to creating an inclusive workplace for all applicants and stakeholders.
See All 43 Registered Nurse Jobs in Kentucky
Find roles in Kentucky that match your experience and apply in just a few clicks.
Find Registered Nurse JobsRegistered Nurse Jobs by City in Kentucky
Where Kentucky roles are concentrated, by current openings.
Registered Nurse Job Market in Kentucky
A snapshot from current Kentucky openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Insurance
What Kentucky Employers Look For
The qualifications that appear most often in registered nurse jobs across Kentucky.
- Active registered nurse license issued or recognized by the Kentucky Board of Nursing
- Associate or bachelor of science in nursing degree from an accredited program
- Current BLS certification required before start date
- One or more years of clinical experience in a relevant care setting
- ACLS or PALS certification for critical care, emergency, or procedural roles
- Strong electronic health record proficiency, with Epic experience preferred
Registered Nurse Jobs in Kentucky: Frequently Asked Questions
How do you become a registered nurse in Kentucky?
To become a registered nurse in Kentucky, you must earn an associate or bachelor of science in nursing from an accredited program, pass the NCLEX-RN exam, and obtain an active license through the Kentucky Board of Nursing. Kentucky participates in the Nurse Licensure Compact, so nurses holding a compact license in another member state can practice in Kentucky without obtaining a separate state license.
How much do registered nurses make in Kentucky?
Registered nurses in Kentucky earn a median of about $81,040 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $64,170 for the lowest 10% to over $111,750 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire registered nurses in Kentucky?
Employers hiring registered nurses in Kentucky right now include St. Elizabeth Healthcare, American Traveler, and Deaconess Health System, based on current listings on Migrate Mate as of August 2026. Kentucky's large integrated health systems, regional hospital networks, and veterans' care facilities are among the most consistent sources of full-time registered nurse openings across the state.
Which Kentucky cities have the most registered nurse jobs?
Louisville, Hopkinsville, and Saint Matthews have the most registered nurse openings in Kentucky. Louisville drives the largest share of demand as the home of Norton Healthcare, Baptist Health, and UofL Health, while Lexington's market is anchored by UK HealthCare and its affiliated medical campus, and Bowling Green supports steady hiring through The Medical Center and regional outpatient growth.
Are there remote registered nurse jobs in Kentucky?
Yes, but they're rare. Registered nursing is a hands-on, patient-facing role, so the vast majority of positions require on-site work in hospitals, clinics, or long-term care settings. About 0% of registered nurse openings tied to Kentucky are remote or hybrid as of August 2026. The roles most likely to be remote are telephone triage nursing, case management, and utilization review positions with insurance carriers or managed care organizations.
How can I get hired as a registered nurse in Kentucky with little or no experience?
The most realistic entry path is applying directly to new-graduate residency programs, which Norton Healthcare, UK HealthCare, and Baptist Health run on rolling or cohort-based cycles. These structured programs pair new nurses with preceptors in a defined specialty over several months. Candidates who lack hospital experience but hold experience as a licensed practical nurse, patient care technician, or certified nursing assistant gain a meaningful advantage, as do those who completed clinical rotations at the hiring facility.
Where can I find and apply to registered nurse jobs in Kentucky?
You can find and apply to registered nurse jobs in Kentucky on Migrate Mate, which lists current Kentucky openings updated regularly. Search the available roles, find the ones that match your specialty, experience level, and preferred location, and apply directly to the ones that fit.
See All 43 Registered Nurse Jobs in Kentucky
Find roles in Kentucky that match your experience and apply in just a few clicks.
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