Registered Nurse Jobs in Oklahoma

Registered Nurse jobs in Oklahoma are concentrated in Oklahoma City and Tulsa, with steady demand across Lawton and the surrounding regional centers for specialties including critical care, emergency nursing, and med-surg. Major systems like INTEGRIS Health, Ascension St. John, and OU Health anchor hiring across acute care, behavioral health, and outpatient settings, with openings at every level from new graduate to charge nurse and clinical supervisor. Demand is consistent and the market absorbs qualified nurses at both bedside and leadership levels throughout the year. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles43
Top employerINTEGRIS Health
Top cityOklahoma City, OK
Cities hiring16
Work type100% On-site
Top industryHealthcare

Showing 5 of 43+ Registered Nurse jobs

Hillcrest HealthCare System
Registered Nurse / RN Neuro ICU
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Hillcrest HealthCare System
New 21h ago
Registered Nurse / RN Neuro ICU
Hillcrest HealthCare System
Tulsa, Oklahoma
Healthcare Administration
Nursing
Patient Services & Wellbeing
Associate's degree
201-500

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Ascension
Registered Nurse OR
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Ascension
New 21h ago
Registered Nurse OR
Ascension
Jenks, Oklahoma
Healthcare Administration
Nursing
Patient Services & Wellbeing
Nursing Diploma
10,000+

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Oak Street Health, part of CVS Health
Registered Nurse
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Oak Street Health, part of CVS Health
Added 1d ago
Registered Nurse
Oak Street Health, part of CVS Health
Oklahoma City, Oklahoma
Executive Leadership & C-Suite
Program Management
Project Management
$54k - $117k/yr
CPR Certification
5,001-10,000

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INTEGRIS Health
Registered Nurse / Emergency Department
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INTEGRIS Health
Added 1d ago
Registered Nurse / Emergency Department
INTEGRIS Health
Edmond, Oklahoma
Business Development
Customer Success
Program Management
Project Management
CPR Certification
10,000+

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Enhabit Home Health & Hospice
Registered Nurse (RN) - Home Health - PRN
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Enhabit Home Health & Hospice
Added 1d ago
Registered Nurse (RN) - Home Health - PRN
Enhabit Home Health & Hospice
Durant, Oklahoma
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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See All 43 Registered Nurse Jobs in Oklahoma

Find roles in Oklahoma that match your experience and apply in just a few clicks.

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Registered Nurse Jobs by City in Oklahoma

Where Oklahoma roles are concentrated, by current openings.

Oklahoma City
12 jobs
Tulsa
9 jobs
Duncan
3 jobs
Edmond
2 jobs
Shawnee
2 jobs
Broken Arrow
2 jobs
Enid
1 job
Jenks
1 job
Durant
1 job

Registered Nurse Job Market in Oklahoma

A snapshot from current Oklahoma openings, updated as new roles post.

Who's Hiring

INTEGRIS Health
INTEGRIS Health6 open roles
SSM Health
SSM Health4 open roles
Saint Francis Health System
Saint Francis Health System4 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What Oklahoma Employers Look For

The qualifications that appear most often in registered nurse jobs across Oklahoma.

  • Active registered nurse license issued or recognized by the Oklahoma Board of Nursing
  • Current BLS certification from the American Heart Association or American Red Cross
  • Associate or bachelor of science in nursing from an accredited nursing program
  • Minimum one year of acute care or clinical nursing experience for most hospital roles
  • Specialty certification such as CCRN, CEN, or ACLS preferred for critical care and emergency positions
  • Proficiency with electronic health record systems including Epic or Cerner

Registered Nurse Jobs in Oklahoma: Frequently Asked Questions

How do you become a registered nurse in Oklahoma?

To become a registered nurse in Oklahoma, you must graduate from an accredited nursing program, pass the NCLEX-RN exam, and obtain a license through the Oklahoma Board of Nursing. Oklahoma participates in the Nurse Licensure Compact, so nurses already holding a compact license from another member state can practice in Oklahoma without applying for a separate state license. A bachelor of science in nursing improves competitiveness for hospital positions.

How much do registered nurses make in Oklahoma?

Registered nurses in Oklahoma earn a median of about $82,920 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,530 for the lowest 10% to over $106,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire registered nurses in Oklahoma?

Companies currently hiring registered nurses in Oklahoma include INTEGRIS Health, SSM Health, and Saint Francis Health System, per current listings on Migrate Mate as of August 2026. Oklahoma's largest health systems, including those operating across Oklahoma City and Tulsa, consistently post the highest volume of openings across acute care, behavioral health, and long-term care settings.

Which Oklahoma cities have the most registered nurse jobs?

Oklahoma City, Tulsa, and Oklahoma account for the most registered nurse openings in Oklahoma. Oklahoma City leads because it is home to the state's largest hospital systems and the OU Health Sciences Center, while Tulsa's concentration of major medical centers and specialty clinics drives strong demand there, and smaller metros like Lawton generate steady openings through regional hospitals serving surrounding rural communities.

Are there remote registered nurse jobs in Oklahoma?

Yes, but they're rare. Registered nursing is fundamentally a hands-on clinical role, so most positions require on-site presence in a hospital, clinic, or care facility. About 0% of registered nurse openings tied to Oklahoma are remote or hybrid as of August 2026, and those that exist are concentrated in utilization review, telephonic case management, and insurance prior authorization roles rather than direct patient care.

How can I get hired as a registered nurse in Oklahoma with little or no experience?

The most realistic entry path is applying directly to new graduate residency programs, which INTEGRIS Health, OU Health, and Ascension St. John run specifically for nurses within their first year of licensure. These structured programs place new grads into med-surg, telemetry, or general acute care units with dedicated preceptorship. Candidates who completed clinical rotations at Oklahoma hospitals already have a relationship advantage, and holding an active Oklahoma Board of Nursing license before applying significantly shortens the time to hire.

Where can I find and apply to registered nurse jobs in Oklahoma?

You can find and apply to registered nurse jobs in Oklahoma on Migrate Mate, which lists current openings across Oklahoma City, Tulsa, and the surrounding region. Search the listings to find roles that match your specialty and experience level, then apply directly to the ones that fit your situation.

See All 43 Registered Nurse Jobs in Oklahoma

Find roles in Oklahoma that match your experience and apply in just a few clicks.

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