Registered Nurse Jobs in Oklahoma

Registered Nurse jobs in Oklahoma are concentrated in Oklahoma City and Tulsa, with steady demand across Lawton and the surrounding regional centers for specialties including critical care, emergency nursing, and med-surg. Major systems like INTEGRIS Health, Ascension St. John, and OU Health anchor hiring across acute care, behavioral health, and outpatient settings, with openings at every level from new graduate to charge nurse and clinical supervisor. Demand is consistent and the market absorbs qualified nurses at both bedside and leadership levels throughout the year. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles82
Top employerINTEGRIS Health
Top cityOklahoma City, OK
Cities hiring21
Work type100% On-site
Top industryHealthcare

Showing 5 of 82+ Registered Nurse jobs

RN Supv Nursing - Stroke/Bariatric IMC Stepdown
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New 22h ago
RN Supv Nursing - Stroke/Bariatric IMC Stepdown
INTEGRIS Health
Oklahoma
Account Management
Business Development
Partnerships & Business Development
Sales
Managed Registered Nurses (RNs)
10,000+

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RN Clinical Research - PRN
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New 23h ago
RN Clinical Research - PRN
EmVenio Research
Mustang, Oklahoma
Clinical Trials
Laboratory Research
Research & Academia
CPR Certification
1,001-5,000

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Registered Nurse I - Heart Hospital Critical Care Float Pool ECB
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New 23h ago
Registered Nurse I - Heart Hospital Critical Care Float Pool ECB
Saint Francis Health System
Tulsa, Oklahoma
Healthcare Administration
Nursing
Patient Services & Wellbeing
Nursing Diploma
10,000+

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MDS Coordinator RN or LPN
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Added 1d ago
MDS Coordinator RN or LPN
Selectis Health
Oklahoma City, Oklahoma
Business Development
Program Management
Project Management
$29 - $35/hr

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Home Health Registered Nurse - PRN
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Added 1d ago
Home Health Registered Nurse - PRN
Elite Home Care Agency LLC
Oklahoma City, Oklahoma
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
BLS Certification

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Registered Nurse Jobs by City in Oklahoma

Where Oklahoma roles are concentrated, by current openings.

Oklahoma City
25 jobs
Tulsa
23 jobs
Norman
7 jobs
Muskogee
5 jobs
Edmond
2 jobs
Quapaw
2 jobs
Stroud
2 jobs
Ada
1 job
Yukon
1 job

Registered Nurse Job Market in Oklahoma

A snapshot from current Oklahoma openings, updated as new roles post.

Who's Hiring

INTEGRIS Health9 open roles
Saint Francis Health System9 open roles
Mercy7 open roles

Top Industries Hiring

  • Healthcare & Medical Services
  • Insurance

What Oklahoma Employers Look For

The qualifications that appear most often in registered nurse jobs across Oklahoma.

  • Active registered nurse license issued or recognized by the Oklahoma Board of Nursing
  • Current BLS certification from the American Heart Association or American Red Cross
  • Associate or bachelor of science in nursing from an accredited nursing program
  • Minimum one year of acute care or clinical nursing experience for most hospital roles
  • Specialty certification such as CCRN, CEN, or ACLS preferred for critical care and emergency positions
  • Proficiency with electronic health record systems including Epic or Cerner

Registered Nurse Jobs in Oklahoma: Frequently Asked Questions

How do you become a registered nurse in Oklahoma?

To become a registered nurse in Oklahoma, you must graduate from an accredited nursing program, pass the NCLEX-RN exam, and obtain a license through the Oklahoma Board of Nursing. Oklahoma participates in the Nurse Licensure Compact, so nurses already holding a compact license from another member state can practice in Oklahoma without applying for a separate state license. A bachelor of science in nursing improves competitiveness for hospital positions.

How much do registered nurses make in Oklahoma?

Registered nurses in Oklahoma earn a median of about $82,920 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,530 for the lowest 10% to over $106,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire registered nurses in Oklahoma?

Companies currently hiring registered nurses in Oklahoma include INTEGRIS Health, Saint Francis Health System, and Mercy, per current listings on Migrate Mate as of October 2026. Oklahoma's largest health systems, including those operating across Oklahoma City and Tulsa, consistently post the highest volume of openings across acute care, behavioral health, and long-term care settings.

Which Oklahoma cities have the most registered nurse jobs?

Oklahoma City, Tulsa, and Norman account for the most registered nurse openings in Oklahoma. Oklahoma City leads because it is home to the state's largest hospital systems and the OU Health Sciences Center, while Tulsa's concentration of major medical centers and specialty clinics drives strong demand there, and smaller metros like Lawton generate steady openings through regional hospitals serving surrounding rural communities.

Are there remote registered nurse jobs in Oklahoma?

Yes, but they're rare. Registered nursing is fundamentally a hands-on clinical role, so most positions require on-site presence in a hospital, clinic, or care facility. About 0% of registered nurse openings tied to Oklahoma are remote or hybrid as of October 2026, and those that exist are concentrated in utilization review, telephonic case management, and insurance prior authorization roles rather than direct patient care.

How can I get hired as a registered nurse in Oklahoma with little or no experience?

The most realistic entry path is applying directly to new graduate residency programs, which INTEGRIS Health, OU Health, and Ascension St. John run specifically for nurses within their first year of licensure. These structured programs place new grads into med-surg, telemetry, or general acute care units with dedicated preceptorship. Candidates who completed clinical rotations at Oklahoma hospitals already have a relationship advantage, and holding an active Oklahoma Board of Nursing license before applying significantly shortens the time to hire.

Where can I find and apply to registered nurse jobs in Oklahoma?

You can find and apply to registered nurse jobs in Oklahoma on Migrate Mate, which lists current openings across Oklahoma City, Tulsa, and the surrounding region. Search the listings to find roles that match your specialty and experience level, then apply directly to the ones that fit your situation.

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