Senior Clinical Informatics Specialist Jobs

Senior Clinical Informatics Specialist jobs are open across health systems, hospitals, academic medical centers, and health IT vendors, from mid-level to senior and lead, with specializations in EHR implementation, clinical decision support, and data analytics. Find a role that fits from the openings below and apply directly.

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Overview

Open roles180+
Top stateCalifornia
Top employerCVS Health
Top citySacramento, CA
Work type47% On-site
Top industryHealthcare

Showing 5 of 180+ Senior Clinical Informatics Specialist jobs

Clinical Informatics Coordinator
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Clinical Informatics Coordinator
HealthONE
Denver, Colorado
Administrative & Office Support
Customer Service
Project Management
$78k - $117k.2/yr
Bachelor of Science
10,000+

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Clinical Informatics Coordinator
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Clinical Informatics Coordinator
Wesley Medical Center
Wichita, Kansas
Clinical Support
Healthcare Administration
Human Resources
Bachelor of Science
1,001-5,000

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Clinical Informatics Systems Analyst II - Health Informatics
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Clinical Informatics Systems Analyst II - Health Informatics
CHRISTUS Health
Tyler, Texas
Accounting
Healthcare Administration
Revenue Operations & Enablement
Bachelor's degree
10,000+

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Clinical Informatics Systems Analyst II - Health Informatics
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Clinical Informatics Systems Analyst II - Health Informatics
CHRISTUS Health
Irving, Texas
Accounting
Healthcare Administration
Revenue Operations & Enablement
Bachelor's degree
10,000+

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Senior Clinical Informatics Specialist - Hybrid
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Senior Clinical Informatics Specialist - Hybrid
Providence
Seattle, Washington
Customer Service
Technical Program Management
$50.32 - $79.45/hr
Hybrid
Master's degree in business administration
10,000+

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Senior Clinical Informatics Specialist Job Market

Who's Hiring

  • CVS Health20
  • Cone Health5
  • Sutter Health5
  • Medpace4
  • CHRISTUS Health4

Top Industries Hiring

  • Healthcare & Medical Services22
  • Insurance9
  • Education4
  • Technology & Software3
  • Biotechnology & Pharmaceuticals3

What Employers Look For

The qualifications that appear most often in senior clinical informatics specialist jobs.

  • Epic, Cerner, or Meditech EHR proficiency with hands-on implementation or optimization experience
  • Clinical background such as an RN, PharmD, or other licensed clinical credential
  • Bachelor's or master's degree in health informatics, nursing, or a related clinical or information science field
  • CPHIMS, CHDA, or vendor-specific EHR certification such as Epic certification
  • Experience with clinical decision support design, workflow analysis, or clinical data governance
  • Proficiency in healthcare data standards including HL7, FHIR, or ICD-10 coding systems

Tips for Your Senior Clinical Informatics Specialist Job Search

Tailor your resume to EHR specifics

Recruiters scan for the exact EHR platform by name, so list Epic, Cerner, or Meditech prominently and note the modules you've configured or trained on. Generic "EHR experience" without specifics gets filtered out before a human reads it.

Highlight clinical background alongside IT skills

Many postings require clinical licensure or a clinical degree, not just technical credentials. Lead with your RN, PharmD, or other clinical credential early in your resume so hiring managers don't assume you're a pure IT candidate and pass you over.

Apply early to roles that fit

Migrate Mate lists senior clinical informatics specialist openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Target postings that match your certification tier

Roles specifying CPHIMS, CHDA, or Epic certification have narrower candidate pools and often faster hiring timelines. Filter your search by certification requirement so you're competing where your credentials give you a concrete advantage.

Prepare a workflow redesign case study for interviews

Interviewers consistently ask for a concrete example of a clinical workflow you improved using informatics tools. Prepare one case study with a before-and-after narrative, the data that drove your decision, and the clinical outcome, so you can adapt it to any panel format.

Negotiate scope before accepting an offer

Senior informatics roles vary widely in decision-making authority, from analyst-level execution to strategy ownership. Ask directly about governance committee access, project leadership autonomy, and whether the role has a path to informatics management before you accept.

Senior Clinical Informatics Specialist Jobs: Frequently Asked Questions

Which companies are hiring the most senior clinical informatics specialists?

The companies hiring the most senior clinical informatics specialists right now include CVS Health, Cone Health, and Sutter Health, with the largest share of openings in California, Texas, and Florida, based on current listings on Migrate Mate as of November 2026. Health systems, academic medical centers, and health IT vendors consistently account for the majority of postings.

How many senior clinical informatics specialist jobs are remote?

About 53% of senior clinical informatics specialist openings are fully remote or hybrid as of November 2026, making this one of the more flexible specialties in clinical operations. Roles centered on EHR optimization, clinical decision support build, and data analytics tend to offer the most remote flexibility, while positions tied to go-live support or end-user training are more likely to require on-site presence.

How do you become a senior clinical informatics specialist?

Start with a clinical degree or licensure, such as nursing or pharmacy, combined with a health informatics credential or graduate coursework. Gain hands-on EHR experience in a clinical or analyst role, then pursue a vendor certification like Epic or a professional credential like CPHIMS. Move into informatics analyst or specialist roles, build a portfolio of workflow improvement projects, and accumulate enough system-level experience to qualify for senior designations.

Can you get hired as a senior clinical informatics specialist with little informatics experience?

It's difficult to enter directly at the senior level without informatics experience, but strong clinical experience on a major EHR platform can substitute in some organizations. Candidates who have served as super-users, led department-level EHR training, or worked on go-live teams often move into junior or mid-level informatics roles first and reach senior designation within a few years of dedicated informatics work.

What does the senior clinical informatics specialist interview process look like?

Most hiring processes include an initial recruiter screen, a technical interview with the informatics or IT team covering EHR platform knowledge and workflow analysis, and a panel interview with clinical stakeholders. Many employers add a practical component where candidates walk through a workflow redesign scenario or demonstrate familiarity with clinical data standards. Final rounds often include a conversation with informatics leadership focused on strategic thinking and cross-departmental communication.

Where can I find and apply to senior clinical informatics specialist jobs?

You can find and apply to senior clinical informatics specialist jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your EHR platform experience, clinical background, and certification level, then apply directly to each listing that fits.

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