Systems Engineer Jobs in South Carolina
Systems Engineer jobs in South Carolina are open across Columbia, Rock Hill, and Greenville and other South Carolina metros, with employers like 3D Systems, Generac Power Systems, and Alrek Business Solutions hiring at every experience level. Find a role that fits below and apply directly.
Find Systems Engineer JobsOverview
Showing 5 of 78+ Systems Engineer jobs
INTRODUCTION
Job Description Summary
Entity
Medical University Hospital Authority (MUHA)
Worker Type
Employee
Worker Sub-Type
Regular
Cost Center
CC005441 SYS - Performance Transformation
Pay Rate Type
Salary
Pay Grade
Health-31
Scheduled Weekly Hours
40
Work Shift
JOB DESCRIPTION
Responsible for the management and coordination of all tasks associated with large projects of high complexity and risk, to include the management and coordination of enterprise projects or multi-agency projects of the highest complexity and risk. Positions in this class assume highly complex, expert-level project management responsibilities. Incumbents are responsible for directing or providing project management consultation for all aspects of the design, development, and implementation of projects.
ADDITIONAL JOB DESCRIPTION
Education:
Bachelors Degree or equivalent
Work Experience:
4-6 years
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
INTRODUCTION
Job Description Summary
Entity
Medical University Hospital Authority (MUHA)
Worker Type
Employee
Worker Sub-Type
Regular
Cost Center
CC005441 SYS - Performance Transformation
Pay Rate Type
Salary
Pay Grade
Health-31
Scheduled Weekly Hours
40
Work Shift
JOB DESCRIPTION
Responsible for the management and coordination of all tasks associated with large projects of high complexity and risk, to include the management and coordination of enterprise projects or multi-agency projects of the highest complexity and risk. Positions in this class assume highly complex, expert-level project management responsibilities. Incumbents are responsible for directing or providing project management consultation for all aspects of the design, development, and implementation of projects.
ADDITIONAL JOB DESCRIPTION
Education:
Bachelors Degree or equivalent
Work Experience:
4-6 years
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
See All 78 Systems Engineer Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Systems Engineer JobsSystems Engineer Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Systems Engineer Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- 3D Systems6
- Generac Power Systems5
- Alrek Business Solutions4
- Fluor4
- M.C. Dean4
Top Industries Hiring
- Technology & Software21
- Consulting & Professional Services15
- Manufacturing15
- Construction & Real Estate7
- Banking & Financial Services6
What South Carolina Employers Look For
The qualifications that appear most often in systems engineer jobs across South Carolina.
- Bachelor's degree in systems engineering, electrical engineering, or a related technical field
- Experience with systems engineering lifecycle processes including requirements definition and verification
- Proficiency with modeling and simulation tools such as MATLAB, Simulink, or SysML
- Familiarity with configuration management and documentation tools like JIRA or DOORS
- Active security clearance or eligibility to obtain one, particularly for defense and government roles
- Experience with integration, testing, and validation across hardware and software subsystems
Systems Engineer Jobs in South Carolina: Frequently Asked Questions
How many systems engineer jobs are there in South Carolina?
There are 78+ systems engineer openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Columbia, Rock Hill, and Greenville. New positions post regularly as employers across South Carolina hire.
Which South Carolina cities have the most systems engineer jobs?
Columbia, Rock Hill, and Greenville have the most systems engineer openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire systems engineers in South Carolina?
Employers hiring systems engineers in South Carolina include 3D Systems, Generac Power Systems, and Alrek Business Solutions, based on current listings on Migrate Mate as of June 2026.
Are there remote systems engineer jobs in South Carolina?
Yes. About 19% of systems engineer openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for systems engineer jobs in South Carolina?
You can apply to systems engineer jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 78 Systems Engineer Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Systems Engineer Jobs