Business Manager Jobs in Irvine, CA
Business manager jobs in Irvine are concentrated in the Irvine Spectrum, the Irvine Business Complex, and Irvine Spectrum Center corridor, with strong demand across technology, financial services, and healthcare. Employers actively hiring include AmCan, GLOVIS America, and EY. Scan the live roles below and apply to whichever ones fit.
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Many structural heart patients suffer from heart failure with limited options. Our Implantable Heart Failure Management (IHFM) business's AI, Product and Platforms organization is at the forefront of addressing these unmet patient needs through pioneering technology that enables early, targeted therapeutic intervention. Our innovative solutions are not just transforming patient care but also creating a unique and exciting environment for our team members. It is our driving force to help patients live longer and healthier lives. Join us and be part of our inspiring journey.
As Senior Manager, Business Systems, you own the end-to-end delivery of the business systems that power IHFM's commercial, clinical operations, and back-office functions as a working leader. This is a hands-on role: you personally lead requirements definition, system configuration, and validation alongside a small team of application developers, administrators, and analysts while owning prioritization, delivery, and outcomes across a portfolio of concurrent initiatives. You are the single point of accountability for translating business needs into scalable, compliant system solutions across the Salesforce ecosystem, enterprise integrations, and the processes that connect them. Business Systems operates as a dedicated team parallel to the IHFM product development teams; its focus is the commercial and enterprise systems that run the business, not product or device software.
Based in Irvine, CA, you'll join a high-impact medtech innovation hub in the heart of Orange County, collaborating in person with cross-functional teams to shape patient-focused technology.
How you'll make an impact
Hands-on delivery and execution (primary focus)
- Personally lead initiatives from requirements through configuration, testing, deployment, and post-launch stabilization. You build and validate, you don't just oversee
- Configure, test, and validate Salesforce workflows, automation, reporting, and integrations directly
- Translate ambiguous or high-level business problems into working technical solutions, consulting enterprise and domain architects as needed
- Own prioritization and backlog management across concurrent initiatives, with disciplined Agile execution: sprint planning, backlog grooming, dependency management, and milestone tracking
- Perform troubleshooting and root-cause analysis; drive process reengineering and optimization end to end
Salesforce and enterprise systems
- Lead delivery of Salesforce enhancements (Sales Cloud and Service Cloud): configuration, automation, reporting, and user workflows
- Own execution of system integrations (ERP, digital health platforms, third-party tools), ensuring reliable, scalable data flows aligned to enterprise architecture standards
- Ensure solutions are fit-for-purpose, scalable, and maintainable
Cross-functional partnership
- Partner with Sales, Clinical Operations, Marketing, and IT to translate business needs into actionable delivery plans, serving as the central point of accountability for business systems initiatives across IHFM
- Act as liaison between business process owners and technical teams; enable super-users through training and knowledge transfer.
- Facilitate alignment across business and technical stakeholders to accelerate decisions and execution
Governance, quality, and compliance
- Drive data quality, reporting, and CRM adoption to support pipeline visibility and commercial effectiveness
- Ensure solutions meet computer system validation (CSV), 21 CFR Part 11, and GxP requirements appropriate to each system's use
- Establish and maintain delivery metrics and KPIs that give transparency into project performance
Team and vendor leadership
- Lead, develop, and mentor a small cross-functional team of application developers, Salesforce administrators, and analysts, working alongside them, not above them
- Manage external vendors and implementation partners to on-time, high-quality delivery
- Foster a culture of accountability, execution excellence, and continuous improvement
What you'll need (Required):
- Bachelor's degree in Information Systems, Computer Science, Business, or a related field
- A minimum of 10 years in business systems delivery, enterprise applications, or business systems analysis, including hands-on configuration and delivery
- A minimum of 3 years leading or mentoring delivery teams while remaining personally involved in build and configuration work
- Demonstrated success delivering large-scale system implementations or enhancements end to end
- Strong hands-on Salesforce experience (Sales Cloud and Service Cloud): configuration, automation, and reporting
- Proven ability to run multiple concurrent projects with competing priorities
- Direct experience with system integrations and data flows across enterprise systems
- Strong command of Agile delivery methodologies and tools
- Ability to travel up to 10%
What else we look for (Preferred):
- Previous people leadership experience
- Experience in MedTech, Life Sciences, or other regulated industries
- Familiarity with digital health platforms and connected device ecosystems
- Working knowledge of computer system validation (CSV), 21 CFR Part 11, FDA, or GxP requirements
- Experience supporting commercial field organizations and sales enablement tools
- Broad enterprise systems exposure (ERP, PLM, QMS, MES, LIMS) and SaaS/vendor management
- PMP, Scrum, or Salesforce certifications
Aligning our overall business objectives with performance, we offer competitive salaries, performance-based incentives, and a wide variety of benefits programs to address the diverse individual needs of our employees and their families.
For California (CA), the base pay range for this position is $139,000 to $196,000 (highly experienced).
The pay for the successful candidate will depend on various factors (e.g., qualifications, education, prior experience). Applications will be accepted while this position is posted on our Careers website.
#LI-Onsite
Edwards is an Equal Opportunity/Affirmative Action employer including protected Veterans and individuals with disabilities.
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Who's Hiring
- AmCan60

- GLOVIS America60

- EY30

- Jobot30

- Qcells30

Top Industries Hiring
- Staffing & Recruiting
Business Manager Jobs in Irvine: Frequently Asked Questions
How do I get a business manager job in Irvine?
Focus your search on Irvine's technology, financial services, and healthcare sectors, which concentrate in areas like the Irvine Spectrum and Irvine Business Complex. Mid-sized tech firms, insurance companies, and health systems here tend to hire business managers with cross-functional experience. Candidates who can show P&L ownership, team leadership, and experience coordinating across operations or product functions stand out in this market.
Which companies hire business managers in Irvine?
Employers hiring business managers in Irvine right now include AmCan, GLOVIS America, and EY, based on current listings on Migrate Mate as of August 2026. Irvine's employer base skews toward established technology firms, financial services companies, and regional healthcare networks, many of which maintain sizable operations and management layers here.
Are there remote business manager jobs in Irvine?
Yes, though it depends on the role. Business manager positions with significant people management, facilities, or on-site operational responsibilities tend to be in-person, while those focused on planning, vendor oversight, or program coordination are more likely to offer flexibility. About 12% of business manager openings tied to Irvine are remote or hybrid as of August 2026, with hybrid arrangements most common among Irvine's technology and financial services employers.
How can I get a business manager job in Irvine with little or no experience?
The most realistic entry path in Irvine is moving into a business manager role from an operations coordinator, project lead, or team lead position within the same company. Irvine's mid-sized technology firms and healthcare organizations regularly promote from within and also hire candidates with strong project management backgrounds in lieu of direct management experience. Completing a PMP or similar credential and targeting associate-level business operations roles at Irvine Spectrum-area employers gives you a concrete foothold.
Which industries hire the most business managers in Irvine?
The sectors hiring the most business managers in Irvine are Staffing & Recruiting, based on current listings on Migrate Mate as of August 2026. Irvine's identity as a hub for technology companies, financial services firms, and healthcare organizations drives consistent demand for business managers who can oversee operations across multiple departments or product lines.
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