Regional Manager Jobs in California
Regional Manager jobs in California are among the most active in the country, concentrated in retail and consumer goods, logistics and distribution, healthcare services, and technology, with openings at every level from first-time managers stepping up from store or district roles to senior regional directors overseeing multi-state territories. Los Angeles, San Francisco, and San Diego are the largest hiring metros for the role, home to anchor employers like Starbucks, Sephora, and Kaiser Permanente, which maintain deep regional management structures across California. The most in-demand specialties are retail operations, healthcare services management, and supply chain and distribution oversight. Find a role that fits below and apply directly.
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A Rare Opportunity to Shape the Future of Genomics
Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
We are looking for a Regional Manager - Prenatal, Northern Los Angeles (San Bernardino, Bakersfield, Santa Monica, Thousand Oaks, Northern Orange County) with 4+ years of direct sales management experience out of Women's Health, Prenatal Diagnostics, or Reproductive Health within Northern Los Angeles. You will build, develop, and lead a high impact team of sales reps who will bring the first and only single-gene NIPT supported carrier and aneuploidy screen to OBGYN clinics, MFMs, and private OBGYN practices throughout the Northern Los Angeles area. You will deliver clinical information to both external clients and internal teams. You will have significant influence over how the test is communicated to physicians and patients, and contribute to how the test evolves to better serve market needs. The Regional Manager - Prenatal is a remote position and reports to the Area Director.
Responsibilities:
- Develop a comprehensive, data-driven sales strategy and business plan to build and grow market development throughout the Northern Los Angeles region
- Build and lead a team of talented, high performing sales reps in the execution of sales strategies and optimization of opportunities to increase profitability and market share
- Recruit, Hire, Train, Manage, and Develop representatives
- Develop and enhance customized pitches to individual OBGYNs, MFMs, and prenatal Genetic Counselors
- Use data to analyze sales results, identify industry trends, and stay abreast of competition to increase sales volume and drive success within territory
Qualifications:
- Minimum 4+ years of field sales management experience leading a team of sales reps at a molecular diagnostics/genetics company required, specifically out of Women's Health, Prenatal, and/or Reproductive Health selling directly to OBGYNs, MFMs, GCs throughout the region, with an existing portfolio of convertible client relationships
- Strong experience hiring, developing, coaching, and motivating a team of sales reps to exceed ambitious sales goals
- Must have prior experience in lab diagnostics
- Demonstrated successful sales track record (eg. multiple award winning - President's Club, Chairman's Club, Circle of Excellence or equivalent), solid negotiation and closing skills, strong data analysis skills, understanding of buyer/decision maker types, exhibit effective selling, listening, presentation skills, strong focus on pull through, and good follow through skills
- Excellent organizational and communication skills (written and verbal) with demonstrated ability to effectively present to both internal and external customers
- Effective time management skills required with a demonstrated ability to assess and prioritize opportunities required
- Exceptionally bright, flexible, self-motivated and results oriented with strong interpersonal and analytical skills and the ability to think strategically as well as execute tactically
- Must act with a sense of urgency, with a focus on closing business
- Ability to assess the needs of OBGYNs & MFMs and their office staff with a focus on consultative sales, coordination of logistics, and problem solving
- Strong desire to work in a startup environment and build out a new territory and team
Nice-to-Haves:
- Experience in a start-up environment
- Clinical laboratory experience
Benefits And Perks:
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousand patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
At BillionToOne, we are proud to offer a combination of (1) base pay (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave etc.).
For this position, we offer a total compensation of $309,972 per year (at plan), including a base salary range of $187,272 per year. Commission potential is uncapped and can be significant.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
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BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA, a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact
Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne's Fetal Cell Capture™ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth
From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding, including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com
See All 118+ Regional Manager Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find Regional Manager JobsRegional Manager Jobs by City in California
Where California roles are concentrated, by current openings.
Regional Manager Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring
- Louis Vuitton6

- Apple5

- Desert Regional Medical Center4

- SiTime4

- BD3

Top Industries Hiring
- Electronics & Hardware15
- Technology & Software14
- Consulting & Professional Services13
- Manufacturing10
- Construction & Real Estate9
What California Employers Look For
The qualifications that appear most often in regional manager jobs across California.
- Bachelor's degree in business administration, management, or a related field required
- Five or more years of progressive management experience across multiple locations or teams
- Demonstrated experience managing P&L, budgets, and financial performance across a region
- Strong knowledge of California labor law, including wage and hour compliance requirements
- Proven ability to recruit, develop, and retain district or location managers
- Proficiency with retail, operations, or enterprise management platforms such as Salesforce or SAP
Regional Manager Jobs in California: Frequently Asked Questions
How do you become a regional manager in California?
Most regional managers in California move up through district or multi-unit management roles after building several years of single-location experience. California does not require a state license to work as a regional manager in most industries, though healthcare-adjacent roles may require credentials recognized by the California Department of Public Health. A bachelor's degree in business or a related field is the standard baseline, and many California employers favor candidates who have managed teams in high-cost, high-regulation markets like Los Angeles or the Bay Area.
How much do regional managers make in California?
Regional managers in California earn a median of about $124,390 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,370 for the lowest 10% to over $293,810 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire regional managers in California?
Employers hiring regional managers in California right now include Louis Vuitton, Apple, and Desert Regional Medical Center, based on current listings on Migrate Mate as of June 2026. California's size and industry diversity mean regional manager roles are particularly active across retail chains, healthcare networks, and logistics companies with large statewide footprints.
Which California cities have the most regional manager jobs?
Los Angeles, San Francisco, and Sacramento consistently post the highest volume of regional manager openings in California. Los Angeles dominates because of its sheer concentration of retail, healthcare, and consumer brand headquarters, while San Francisco and San Diego attract regional management roles tied to technology companies, biotech, and large integrated health systems that require dedicated regional leadership structures.
Are there remote regional manager jobs in California?
Yes, but they're rare. Regional managers are typically responsible for in-person oversight of multiple sites, stores, or clinics, which makes fully remote arrangements uncommon by nature. About 22% of regional manager openings tied to California are remote or hybrid as of June 2026, and those positions tend to involve strategy, reporting, and vendor coordination rather than daily field presence.
How can I get hired as a regional manager in California with little or no experience?
The most realistic entry path is moving from a high-performing assistant manager or store manager role into a district manager position, then working toward regional scope. Large California retailers like Target and Whole Foods, as well as healthcare networks such as Kaiser Permanente and Dignity Health, run structured leadership development programs that pipeline store-level managers into multi-unit roles. Building experience in California's competitive Los Angeles or Bay Area markets, where managing complex labor environments and high volume is common, signals readiness for regional responsibility more convincingly than equivalent experience in smaller markets.
Where can I find and apply to regional manager jobs in California?
You can find and apply to regional manager jobs in California on Migrate Mate, which lists current California openings across industries and metro areas. Find roles that fit your experience and location and apply directly to the employers posting them.
See All 118+ Regional Manager Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find Regional Manager Jobs