Clinic Registered Nurse Jobs in Mississippi
Clinic Registered Nurse jobs in Mississippi are concentrated in Jackson, Hattiesburg, and Gulfport, where ambulatory care, family medicine, and chronic disease management drive steady clinic hiring across the state. Major health systems including University of Mississippi Medical Center, Forrest Health, and Memorial Hospital at Gulfport maintain ongoing clinic nurse staffing across primary care, specialty, and community health settings. Demand runs from new graduates entering outpatient care to experienced nurses specializing in pediatrics, women's health, and internal medicine clinics. See the openings below and apply to the ones that match your experience.
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At Singing River Health System, caring isn’t just part of the job — it’s in our DNA. Whether we’re saving lives, supporting behind the scenes, or showing up for our community, we bring the energy, heart, and hustle every single day.
With pride, passion, and commitment, we will improve health and save lives in our community every day.
Shift:
Monday - Friday (8:00 AM - 4:30 PM)Location:
Singing River NeurologyJob Description Summary
Job Description
Position Overview:
The Clinic Registered Nurse performs under the direct supervision of the Physician and the Practice Manager/Administrator. He/She is a liaison between the patient, physician, and various other components of patient care. The RN assists the physician by taking histories and physician orders; scheduling and evaluating referrals; suture removal; dressing changes; and other responsibilities within the RN scope of practice. He/She assists the patient with health education, medication refills, and general questions about their care.
DISCLAIMER: This is not necessarily an exhaustive list of all responsibilities, duties, skills, efforts, requirements or working conditions associated with the job. While this intends to be an accurate reflection of the current job, management reserves the right to revise the job or to require that other or different tasks performed as assigned.
Education:
Graduate from NLN school of nursing required.
License:
Currently licensed to practice as a Registered Nurse in the State of Mississippi.
Certifications:
Must complete and maintain BCLS certification upon hire and/or transfer.
Must have de-escalation training completed by the end of position orientation (90 days); must have appropriate level of de-escalation training.
Experience:
Minimum of three years experience in nursing preferred. Must maintain current continuing education units (CEUs). Must possess current skill level for wound care including staple/suture removal.
Reports to:
Provider for direct clinical supervision; Practice Manager/Administrator and/or Director of Practice Development for general supervision.
Supervises:
Other nursing staff as assigned
Physical Demands:
Work is moderately active: involves sitting with frequent requirements to move about the office, move about the facility, and to travel to another facility within the SRHS service area. Work involves exerting a negligible amount of force frequently to lift, carry, push, pull, or otherwise move objects, including the human body. Work involves using repetitive motions: substantial movements of the wrists, hands and/or fingers while operating standard office equipment such as computer keyboard copier and 10-key.
Work involves being able to perceive the nature of sound at normal speaking levels with or without correction; the ability to make fine discriminations in sound. Work requires close visual and acuity and the ability to adjust the eye to bring an object into sharp focus, i.e. shift gaze from viewing a computer monitor to forms/printed material that are closer to compare data at close vision.
Must be able to work for extended periods of time without experiencing undue fatigue. Must be able to work flexible hours.
Mental Demands:
Must possess keen mental faculties in the management of information and clinical situations. Communication / speaking / enunciation skills to receive and give information in person and by telephone. Emotional stability conducive to dealing with high stress level for 6-8 hours/8 hour shifts associated with ongoing and changing needs of clinical areas as related to computer use and demands of maintaining effective working relationships with peers, physicians and other healthcare workers.
Special Demands:
Must possess superior customer service skills and professional etiquette. Must possess proficient knowledge and ability to use a computer (must be keyboard proficient) and other office technology (i.e., telephone, fax, etc.), MS Outlook and Word.
If you’re looking for purpose, teamwork, and a place where what you do truly matters, you’ve found it. Let’s do big things together. Apply now and join our team.
See All 27 Clinic Registered Nurse Jobs in Mississippi
Find roles in Mississippi that match your experience and apply in just a few clicks.
Find Clinic Registered Nurse JobsClinic Registered Nurse Jobs by City in Mississippi
Where Mississippi roles are concentrated, by current openings.
Clinic Registered Nurse Job Market in Mississippi
A snapshot from current Mississippi openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What Mississippi Employers Look For
The qualifications that appear most often in clinic registered nurse jobs across Mississippi.
- Active registered nurse license issued or recognized by the Mississippi Board of Nursing
- Current BLS certification required at time of hire or within a defined onboarding period
- Associate or Bachelor of Science in Nursing degree from an accredited nursing program
- Minimum one year of clinical nursing experience in an outpatient or ambulatory care setting
- Proficiency with electronic health record systems such as Epic or Athenahealth
- Strong patient education skills and experience managing chronic condition care plans
Clinic Registered Nurse Jobs in Mississippi: Frequently Asked Questions
How do you become a clinic registered nurse in Mississippi?
You become a clinic registered nurse in Mississippi by earning an Associate Degree in Nursing or a Bachelor of Science in Nursing from an accredited program, passing the NCLEX-RN exam, and obtaining licensure through the Mississippi Board of Nursing. The Board issues a standard RN license and also participates in the Nurse Licensure Compact, which allows nurses licensed in other compact states to practice in Mississippi without a separate application.
How much do clinic registered nurses make in Mississippi?
Clinic registered nurses in Mississippi earn a median of about $77,090 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,610 for the lowest 10% to over $100,350 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinic registered nurses in Mississippi?
Mississippi clinic registered nurse roles are posted by Singing River Health System, NORTH MISSISSIPPI HEALTH SERVICES, and FMOL Health and others right now, based on current listings on Migrate Mate as of October 2026. Mississippi's largest health systems and federally qualified health centers account for a significant share of clinic nurse openings, particularly in underserved rural counties where ambulatory staffing needs are high.
Which Mississippi cities have the most clinic registered nurse jobs?
Ocean Springs, Jackson, and Mississippi lead Mississippi in clinic registered nurse openings. Jackson drives volume as the state capital and home to University of Mississippi Medical Center and its affiliated outpatient network, while Hattiesburg and Gulfport generate openings through regional health systems and the coastal medical corridor that serves a broad patient population across the Pine Belt and Gulf Coast.
Are there remote clinic registered nurse jobs in Mississippi?
Yes, but they're rare. About 0% of clinic registered nurse openings tied to Mississippi are remote or hybrid as of October 2026, reflecting that most clinic nursing work requires in-person patient assessment and hands-on care. The portions of the role most likely to shift to remote or phone-based formats are nurse triage, care coordination follow-up calls, and chronic disease management check-ins.
How can I get hired as a clinic registered nurse in Mississippi with little or no experience?
The most realistic entry path is applying to new-graduate nurse residency programs, which University of Mississippi Medical Center and Forrest Health run specifically for nurses with limited clinical hours. Starting in a med-surg or urgent care float role and then requesting a transfer to an outpatient clinic is another well-used route. Candidates with a current Mississippi RN license, a completed capstone in an ambulatory setting, and BLS certification are most competitive for these entry-level clinic openings.
Where can I find and apply to clinic registered nurse jobs in Mississippi?
You can find and apply to clinic registered nurse jobs in Mississippi on Migrate Mate, which lists current openings tied to the state. Search the listings to find roles that match your experience, specialty focus, and preferred location, then apply directly to the ones that fit. No sign-up is needed to see the openings.
See All 27 Clinic Registered Nurse Jobs in Mississippi
Find roles in Mississippi that match your experience and apply in just a few clicks.
Find Clinic Registered Nurse Jobs