Clinical Nurse Jobs in Kentucky

Clinical Nurse jobs in Kentucky are in strong demand, concentrated in acute care hospitals, long-term care facilities, and outpatient health systems, with openings at every level from new graduate to senior clinical staff. Louisville, Lexington, and Bowling Green are the primary hiring markets, anchored by major systems such as Norton Healthcare, UK HealthCare, and Baptist Health. The most consistently sought specialties include medical-surgical, critical care, and pediatric nursing. Find a role that fits below and apply directly.

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Overview

Open roles30
Top employerAppalachian Regional Healthcare
Top cityLouisville, KY
Cities hiring15
Work type75% On-site
Top industryHealthcare

Showing 5 of 30+ Clinical Nurse jobs

Clinical Nurse (RN) Manager
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Added 3d ago
Clinical Nurse (RN) Manager
Hosparus Health
Louisville, Kentucky
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor's degree
501-1,000

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Registered Nurse (RN) Clinical Manager of Home Health
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Added 4d ago
Registered Nurse (RN) Clinical Manager of Home Health
Alternate Solutions Health Network
Louisville, Kentucky
Healthcare Administration
Nursing
Patient Services & Wellbeing
1,001-5,000

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Clinical Nurse Educator Perioperative
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Added 5d ago
Clinical Nurse Educator Perioperative
Appalachian Regional Healthcare
Lexington, Kentucky
Higher Education
K-12 Teaching
Teaching & Instruction
Master's degree in education
5,001-10,000

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ICU CCU Clinical Nurse Coordinator
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Added 6d ago
ICU CCU Clinical Nurse Coordinator
TriStar Health
Bowling Green, Kentucky
Healthcare Administration
Nursing
Patient Services & Wellbeing
5,001-10,000

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Dialysis Clinical Manager Registered Nurse - RN
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Added 1w ago
Dialysis Clinical Manager Registered Nurse - RN
Fresenius Medical Care
Louisville, Kentucky
Healthcare Administration
Nursing
Patient Services & Wellbeing
Managed Registered Nurses (RNs)
10,000+

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See All 30 Clinical Nurse Jobs in Kentucky

Find roles in Kentucky that match your experience and apply in just a few clicks.

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Clinical Nurse Jobs by City in Kentucky

Where Kentucky roles are concentrated, by current openings.

Louisville
7 jobs
Bowling Green
6 jobs
Lexington
4 jobs
Prestonsburg
2 jobs
Harlan
1 job
Hazard
1 job
Franklin
1 job
Mayfield
1 job
Somerset
1 job

Clinical Nurse Job Market in Kentucky

A snapshot from current Kentucky openings, updated as new roles post.

Who's Hiring

Appalachian Regional Healthcare9 open roles
TriStar Health5 open roles
Med Center Health3 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What Kentucky Employers Look For

The qualifications that appear most often in clinical nurse jobs across Kentucky.

  • Active Kentucky Registered Nurse license issued by the Kentucky Board of Nursing
  • Associate or Bachelor of Science in Nursing from an accredited nursing program
  • Current BLS certification required, with ACLS preferred for acute care settings
  • Minimum one to two years of clinical experience in a hospital or comparable setting
  • Demonstrated proficiency with electronic health record systems such as Epic or Cerner
  • Strong communication skills and ability to collaborate within multidisciplinary care teams

Clinical Nurse Jobs in Kentucky: Frequently Asked Questions

How do you become a clinical nurse in Kentucky?

To become a clinical nurse in Kentucky, you must earn an Associate Degree in Nursing or a Bachelor of Science in Nursing from an accredited program, then pass the NCLEX-RN exam to obtain licensure through the Kentucky Board of Nursing. Kentucky participates in the Nurse Licensure Compact, so nurses licensed in other compact states may practice in Kentucky without obtaining a separate state license. Most clinical positions require an active, unencumbered Kentucky RN license before your start date.

How much do clinical nurses make in Kentucky?

Clinical nurses in Kentucky earn a median of about $81,040 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $64,170 for the lowest 10% to over $111,750 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical nurses in Kentucky?

Companies currently hiring clinical nurses in Kentucky include Appalachian Regional Healthcare, TriStar Health, and Med Center Health, per current listings on Migrate Mate as of October 2026. Kentucky's largest health systems, including regional academic medical centers and community hospital networks, tend to post the highest volume of clinical nurse openings across the state year-round.

Which Kentucky cities have the most clinical nurse jobs?

The Kentucky cities with the most clinical nurse openings are Louisville, Bowling Green, and Lexington. Louisville leads because it is home to the state's largest hospital systems and a dense concentration of acute care and specialty facilities, while Lexington's demand is driven by UK HealthCare and its affiliated academic medical complex, and Bowling Green reflects the growing regional health infrastructure serving south-central Kentucky.

Are there remote clinical nurse jobs in Kentucky?

Yes, but they're rare. Clinical nursing is fundamentally a hands-on, bedside role, so the vast majority of positions require on-site presence in a hospital, clinic, or care facility. About 25% of clinical nurse openings tied to Kentucky are remote or hybrid as of October 2026, and those tend to be in adjacent functions such as telephonic case management, utilization review, or nurse triage roles rather than direct patient care.

How can I get hired as a clinical nurse in Kentucky with little or no experience?

The most realistic entry path is applying to a nurse residency program, which large Kentucky employers such as Norton Healthcare and UK HealthCare run specifically for new graduates transitioning into hospital practice. Medical-surgical and telemetry units typically have the highest entry-level openings, and experience in adjacent roles such as patient care technician or licensed practical nurse can help you move into an RN position sooner. Holding an active, unencumbered Kentucky RN license and a current BLS certification before you apply gives you a clear edge over candidates still awaiting results.

Where can I find and apply to clinical nurse jobs in Kentucky?

You can find and apply to clinical nurse jobs in Kentucky on Migrate Mate, which lists current Kentucky openings from employers actively hiring in the state. Find roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.

See All 30 Clinical Nurse Jobs in Kentucky

Find roles in Kentucky that match your experience and apply in just a few clicks.

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