Clinical Research Manager Jobs in District of Columbia
Clinical Research Manager jobs in District of Columbia are among the most active in the country, concentrated in federal agency research programs, major academic medical centers, and a dense network of contract research organizations and life sciences nonprofits. Most hiring is centered in Washington, D.C., with additional demand in Bethesda and Silver Spring across the Maryland suburbs, where institutions like George Washington University Hospital, MedStar Health, and the NIH Clinical Center maintain ongoing research operations. Protocol management, regulatory affairs oversight, and oncology and infectious disease trial management are the most consistently sought specializations. Find a role that fits below and apply directly.
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Implements and coordinates research and administrative procedures for the successful management of clinical trials. Performs diverse administrative duties requiring analysis sound judgment and a high level of knowledge of study specific protocols. Enters study and/or research participant data into the Clinical Trial Management System (CTMS) as applicable.
- Regulatory responsibilities include the oversight and/or responsibility for the Intuitional Review Board (IRB) submissions and other related regulatory forms (e.g. scientific review) and adhering to the timelines of the study start-up process; developing informed consent documents and other documents as applicable; supporting the safety of clinical research participants; ensureing the appropriate delegation of study related tasks (i.e. Delegation of Authority).
- Explains the informed consent process and the study to the research participant (e.g. purpose duration risks/benefits) and obtains all required signatures; ensures the research participant has sufficient time and opportunity to ask the investigator medical questions; documents the informed consent process in the source document and provides the research participant with a copy of the informed consent.
- Develops an effective recruitment plan (e.g. central recruitment core); recruits research participants and discuss study protocol; educates research participants about protocol expectations and meets with research participants for each visit and maintains accessibility to discuss any questions or concerns regarding the study;
- Oversees the development of advertising materials; participates in teleconferences and/or meetings to review study progress and conduct.
- Data entry responsibilities include the completion and maintenance of case report forms and reviews data against the research participant's medical record for completeness and accuracy; addressing all queries clarifications and outstanding data queries and appropriately communicating with the sponsor and/or Contract Research Organization (CRO); completing and submitting case report forms on as close to a real time basis as possible.
- Ensures proper collection processing and shipment of biospecimens and pharmacokinetics as applicable (e.g. centrifuge freezing refrigeration) and maintains current Occupational Safety and Health Administration (OSHA) training regarding Bloodborne Pathogens;
- Assists with maintaining equipment (e.g. calibration preventive maintenance); communicates with manager investigator and sponsor regarding abnormal laboratory values; maintains Internal Air and Transportation Association (IATA) training for routine packaging labeling and transporting of biological materials.
- Study conduct responsibilities include research participant interviews and assessments at study visits as required by protocol; assessing and ensuring research participant safety through study participation; maintaining close communication with investigator;
- Attending investigator meetings as appropriate and communicating relevant information to the research team; understanding and proficiently communicating all components of research documents such as protocol investigator brochure and research instructions.
- Receives and maintains test articles from sponsor and inventory test articles; works with research pharmacist as applicable; stores test article supplies according to Food and Drug Administration (FDA) regulations and sponsor requirements; administers test article as appropriate;
- Retrieves test articles and calculates research participant compliance; maintains randomization and emergency codes of test article; documents on accountability log and research participant record (e.g. test article received used disposed).
- Ensures that non-serious and serious adverse events are properly identified documented and reported according to all applicable requirements; presents investigator with relevant information for determination of seriousness causality and intervention; acts on investigator's recommendation for adverse event intervention (e.g. stop test article call research participant re-test treat); maintains follow-up to determine resolution of adverse event.
- Understands and complies with rules for billing Medicare Medicaid and third party payors for services drugs devices tests and procedures rendered in the clinical research context;
- Responsible for reviewing understanding and accepting the billing matrix/billing plan generated by administration for research participants enrolled in clinical studies; ensures research participant stipends have been routed in a timely manner as applicable.
- Study close-out responsibilities include return or disposition of unused supplies per sponsors requirement; reconciling test article accountability; document research participants who are lost to follow-up or who have dropped out (e.g. causes contact efforts); ensuring long term storage of documents; submitting IRB closing report (i.e. termination) after sponsor has closed study site.
- Acts as a liaison with research participants investigators sponsors and healthcare professionals; prepares for site qualification study initiation monitoring and close-out visits;
- Ensures all research participant encounters are updated as appropriate and within one business day in clinical trial management system (CTMS); works effectively with multidisciplinary ancillary and inter-professional research teams; possesses a basic understanding of scientific center goals and the importance of serving our customers.
Education
- Bachelor's degree or an allied health or related professional degree required, or equivalent work experience
- 2 years of relevant clinical research experience required
- Experience in a healthcare setting preferred
- Undergraduate and/or work experiences that demonstrates aptitude for research facilitation preferred
- Verbal and written communication skills.
- Basic computer skills preferred.
See All 28 Clinical Research Manager Jobs in District of Columbia
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Find JobsClinical Research Manager Jobs by City in District of Columbia
Where District of Columbia roles are concentrated, by current openings.
Clinical Research Manager Job Market in District of Columbia
A snapshot from current District of Columbia openings, updated as new roles post.
Who's Hiring
- Children's National Hospital17

- Georgetown University3

- Johns Hopkins University3

- The Henry M. Jackson Foundation for the Advancement of Military Medicine2

- Parexel1

Top Industries Hiring
- Healthcare & Medical Services19
- Education5
- Science & Research2
- Biotechnology & Pharmaceuticals1
What District of Columbia Employers Look For
The qualifications that appear most often in clinical research manager jobs across District of Columbia.
- Bachelor's or master's degree in life sciences, clinical research, or a related field required
- Minimum five years of clinical trial experience including supervisory or team lead responsibilities
- Certification as a Clinical Research Professional (CCRP) or equivalent strongly preferred by D.C. employers
- Demonstrated proficiency with FDA regulations, GCP guidelines, and IRB submission processes
- Experience managing multi-site trials and coordinating with CROs or federal research partners
- Strong familiarity with electronic data capture systems such as Medidata Rave or Oracle Clinical
Clinical Research Manager Jobs in District of Columbia: Frequently Asked Questions
How do you become a clinical research manager in District of Columbia?
Most clinical research manager roles in D.C. require a bachelor's degree in a life science or health-related field, with a master's degree increasingly preferred at academic medical centers and federal research programs. There is no D.C.-specific state license for this role, but employers consistently expect credentials such as the CCRP through the Society of Clinical Research Associates or the CCRA through the Association of Clinical Research Professionals, both nationally recognized and widely accepted by D.C. hiring institutions.
Which companies hire clinical research managers in District of Columbia?
Employers hiring clinical research managers in District of Columbia right now include Children's National Hospital, Georgetown University, and Johns Hopkins University, based on current listings on Migrate Mate as of July 2026. D.C.'s concentration of federal health agencies, academic medical centers, and globally active contract research organizations makes it one of the more consistent markets for this role year-round.
Which District of Columbia cities have the most clinical research manager jobs?
The cities with the most clinical research manager openings in District of Columbia are Washington. Washington, D.C. anchors the market through its federal health agencies and university hospitals, while Bethesda and Silver Spring draw significant demand from the NIH campus and the large CRO and biotech offices concentrated along the I-270 corridor.
Are there remote clinical research manager jobs in District of Columbia?
Yes, but they're limited compared to purely desk-based roles, since much of the work involves on-site trial oversight and staff supervision. About 22% of clinical research manager openings tied to District of Columbia are remote or hybrid as of July 2026, reflecting a mix of options across the market. Protocol review, regulatory submissions, and vendor coordination are the functions most commonly performed remotely when employers do offer flexible arrangements.
How can I get hired as a clinical research manager in District of Columbia with little or no experience?
The most realistic path is starting as a clinical research coordinator or clinical trials assistant with a D.C.-area academic medical center or federal research program, such as those affiliated with George Washington University, Georgetown University Medical Center, or MedStar Health. Many of these institutions run structured coordinator development programs for candidates with a relevant degree but limited trial experience. Earning a CCRP credential early and gaining IRB and data management exposure in a coordinator role are the steps that most consistently lead to manager-track consideration in the D.C. market.
Where can I find and apply to clinical research manager jobs in District of Columbia?
You can find and apply to clinical research manager jobs in District of Columbia on Migrate Mate, which lists current openings tied to the D.C. market. Search the available roles, find the ones that fit your background and target institutions, and apply directly to each one.
See All 28 Clinical Research Manager Jobs in District of Columbia
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