Clinical Research Manager Jobs in Pennsylvania
Clinical Research Manager jobs in Pennsylvania are in strong demand, with openings concentrated in pharmaceutical research, academic medical centers, and large health system-sponsored trials serving candidates from coordinator-level through senior management. Philadelphia, Pittsburgh, and King of Prussia are the primary hiring hubs, anchored by employers such as Penn Medicine, UPMC, and GSK. The most in-demand specialties include oncology trial management, regulatory affairs oversight, and Phase II through IV study coordination. Find a role that fits below and apply directly.
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Clinical Research Coord II
The Lung Transplant Research Division at UPMC is a dynamic and highly specialized research department dedicated to advancing clinical knowledge and improving outcomes for lung transplant patients. The division supports a diverse and growing research portfolio, currently managing clinical research studies in various phases of enrollment, start-up, and follow-up, with additional studies anticipated in the near future.
The research team consists of one dedicated Research Coordinator and two Primary Investigators who work collaboratively with a multidisciplinary group of ancillary support staff, including Physician Assistants (PAs), Certified Registered Nurse Practitioners (CRNPs), operating room personnel, physicians, and other clinical and administrative staff. Together, these individuals contribute to the successful execution of research activities, regulatory compliance, patient recruitment, data collection, and study oversight.
Research activities are conducted across multiple UPMC facilities, including the UPMC Shadyside Medical Building, Falk Medical Building, and the UPMC Presbyterian operating rooms, requiring close coordination among clinical and research personnel.
This position plays a critical role in supporting the division's research mission by ensuring high-quality study conduct, fostering collaboration among multidisciplinary teams, and contributing to the ongoing expansion of innovative research opportunities within the Lung Transplant Program.
Qualifications Required:
- Bachelor's degree in a health science, biological science, nursing, public health, or related field.
- Experience coordinating clinical research studies or equivalent research experience; knowledge of clinical research methodology and regulatory requirements; strong organizational, communication, and interpersonal skills; proficiency with Microsoft Word and Excel.
Qualifications Preferred:
Clinical research coordination experience in transplant, thoracic surgery, pulmonary medicine, or related specialties. Experience with patient screening, recruitment, and informed consent processes: experience with protocol management and regulatory submissions to the IRB and other oversight committees; experience with research databases and electronic data capture systems; familiarity with GCP, human subject protections, and research compliance requirements.
Conducts research assessments on study participants. Assists with and adheres to Institutional Review Board (IRB) renewal, modification, and approved protocols. Assists with training staff. Ensures adherence to protocols and corrects issues with data collection.
The position will coordinate and manage day-to-day operations of clinical research studies within the Lung Transplant Program; screen, recruit, consent, and enroll research participants in accordance with approved protocols and regulatory requirements; maintain compliance with Good Clinical Practice (GCP), institutional policies, sponsor guidelines, and applicable federal regulations. GCP compliance is a foundational component of research study conduct. In addition, the position will be responsible for:
- Prepare and submit regulatory documents, including but not limited to Institutional Review Board (IRB) submissions, continuing reviews, amendments, and study closures.
- Coordinate study visits, specimen collection, and research-related procedures.
- Perform accurate and timely data collection, entry, verification, and database management.
- Maintain study files and regulatory binders and ensure completion of required study documentation.
- Assist investigators with protocol implementation and ongoing study management.
- Collaborate with multidisciplinary clinical and research teams across multiple locations.
Participate in study monitoring visits, audits, and sponsor communications as needed.
Physical Effort
- Ability to sit, stand, and walk for extended periods of time.
- Ability to travel between UPMC Presbyterian and UPMC Shadyside campuses.
- Ability to transport study materials and equipment as needed.
- Must have reliable transportation for travel between clinical and research sites.
The University of Pittsburgh is an equal opportunity employer / disability / veteran.
Clinical Research Coord II
The Lung Transplant Research Division at UPMC is a dynamic and highly specialized research department dedicated to advancing clinical knowledge and improving outcomes for lung transplant patients. The division supports a diverse and growing research portfolio, currently managing clinical research studies in various phases of enrollment, start-up, and follow-up, with additional studies anticipated in the near future.
The research team consists of one dedicated Research Coordinator and two Primary Investigators who work collaboratively with a multidisciplinary group of ancillary support staff, including Physician Assistants (PAs), Certified Registered Nurse Practitioners (CRNPs), operating room personnel, physicians, and other clinical and administrative staff. Together, these individuals contribute to the successful execution of research activities, regulatory compliance, patient recruitment, data collection, and study oversight.
Research activities are conducted across multiple UPMC facilities, including the UPMC Shadyside Medical Building, Falk Medical Building, and the UPMC Presbyterian operating rooms, requiring close coordination among clinical and research personnel.
This position plays a critical role in supporting the division's research mission by ensuring high-quality study conduct, fostering collaboration among multidisciplinary teams, and contributing to the ongoing expansion of innovative research opportunities within the Lung Transplant Program.
Qualifications Required:
- Bachelor's degree in a health science, biological science, nursing, public health, or related field.
- Experience coordinating clinical research studies or equivalent research experience; knowledge of clinical research methodology and regulatory requirements; strong organizational, communication, and interpersonal skills; proficiency with Microsoft Word and Excel.
Qualifications Preferred:
Clinical research coordination experience in transplant, thoracic surgery, pulmonary medicine, or related specialties. Experience with patient screening, recruitment, and informed consent processes: experience with protocol management and regulatory submissions to the IRB and other oversight committees; experience with research databases and electronic data capture systems; familiarity with GCP, human subject protections, and research compliance requirements.
Conducts research assessments on study participants. Assists with and adheres to Institutional Review Board (IRB) renewal, modification, and approved protocols. Assists with training staff. Ensures adherence to protocols and corrects issues with data collection.
The position will coordinate and manage day-to-day operations of clinical research studies within the Lung Transplant Program; screen, recruit, consent, and enroll research participants in accordance with approved protocols and regulatory requirements; maintain compliance with Good Clinical Practice (GCP), institutional policies, sponsor guidelines, and applicable federal regulations. GCP compliance is a foundational component of research study conduct. In addition, the position will be responsible for:
- Prepare and submit regulatory documents, including but not limited to Institutional Review Board (IRB) submissions, continuing reviews, amendments, and study closures.
- Coordinate study visits, specimen collection, and research-related procedures.
- Perform accurate and timely data collection, entry, verification, and database management.
- Maintain study files and regulatory binders and ensure completion of required study documentation.
- Assist investigators with protocol implementation and ongoing study management.
- Collaborate with multidisciplinary clinical and research teams across multiple locations.
Participate in study monitoring visits, audits, and sponsor communications as needed.
Physical Effort
- Ability to sit, stand, and walk for extended periods of time.
- Ability to travel between UPMC Presbyterian and UPMC Shadyside campuses.
- Ability to transport study materials and equipment as needed.
- Must have reliable transportation for travel between clinical and research sites.
The University of Pittsburgh is an equal opportunity employer / disability / veteran.
See All 87 Clinical Research Manager Jobs in Pennsylvania
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Find JobsClinical Research Manager Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Clinical Research Manager Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
- University of Pennsylvania19
- University of Pittsburgh11
- Thomas Jefferson University & Jefferson Health10
- Children's Hospital of Philadelphia5
- Penn State Health4
Top Industries Hiring
- Healthcare & Medical Services14
- Education6
- Science & Research1
- Agriculture & Farming1
- Biotechnology & Pharmaceuticals1
What Pennsylvania Employers Look For
The qualifications that appear most often in clinical research manager jobs across Pennsylvania.
- Bachelor's or master's degree in life sciences, nursing, or a related clinical field
- Minimum five years of clinical research experience with at least two in a supervisory role
- Certified Clinical Research Professional (CCRP) or equivalent credential strongly preferred
- Demonstrated experience managing ICH-GCP compliance and FDA regulatory submissions
- Proficiency with electronic data capture systems such as Medidata Rave or Veeva Vault
- Experience overseeing multi-site trial budgets, contracts, and sponsor communications
Clinical Research Manager Jobs in Pennsylvania: Frequently Asked Questions
How do you become a clinical research manager in Pennsylvania?
The most direct path is a bachelor's degree in a life science, nursing, or health-related field followed by several years of hands-on clinical research coordination experience. Pennsylvania does not require a state-issued license to manage clinical trials, but most employers expect certification through the Society of Clinical Research Associates (SOCRA) or the Association of Clinical Research Professionals (ACRP). Large academic medical centers and pharmaceutical employers in the Philadelphia corridor typically require demonstrated GCP training and trial management experience before promoting into a manager role.
Which companies hire clinical research managers in Pennsylvania?
Employers hiring clinical research managers in Pennsylvania right now include University of Pennsylvania, University of Pittsburgh, and Thomas Jefferson University & Jefferson Health, based on current listings on Migrate Mate as of August 2026. Pennsylvania's dense concentration of health systems and pharmaceutical headquarters along the southeastern corridor means sustained hiring across both sponsor-side and site-side research operations throughout the year.
Which Pennsylvania cities have the most clinical research manager jobs?
Philadelphia, Pittsburgh, and Hershey account for the most clinical research manager openings in Pennsylvania. Philadelphia dominates because of its cluster of academic medical centers, large hospital systems, and major pharmaceutical and biotech employers, while Pittsburgh draws significant volume from UPMC's research enterprise, and suburban markets like King of Prussia benefit from the headquarters and regional offices of several global pharmaceutical companies.
Are there remote clinical research manager jobs in Pennsylvania?
Yes, and more than many clinical roles, because a meaningful portion of the work involves data oversight, vendor management, and regulatory documentation rather than direct patient contact. About 50% of clinical research manager openings tied to Pennsylvania are remote or hybrid as of August 2026, reflecting growing sponsor and CRO flexibility. Sponsor-side and CRO roles tend to offer the most remote options, while site-based positions at hospitals or academic centers typically require on-site presence.
How can I get hired as a clinical research manager in Pennsylvania with little or no experience?
The most realistic entry point is a clinical research coordinator or research associate role at a Pennsylvania academic medical center or health system such as Jefferson Health, Temple Health, or Children's Hospital of Philadelphia, which regularly hire coordinators without prior research management experience. From there, earning an ACRP or SOCRA certification while managing a protocol independently is the clearest route to a manager title. Candidates with adjacent backgrounds in nursing, pharmacy, or regulatory affairs at Pennsylvania-based pharmaceutical companies often make lateral moves that accelerate the path into management.
Where can I find and apply to clinical research manager jobs in Pennsylvania?
You can find and apply to clinical research manager jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings across health systems, pharmaceutical companies, and contract research organizations. Find roles that fit your experience and location and apply directly from the listing.
See All 87 Clinical Research Manager Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
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