Clinical Research Manager Jobs in Pennsylvania
Clinical Research Manager jobs in Pennsylvania are in strong demand, with openings concentrated in pharmaceutical research, academic medical centers, and large health system-sponsored trials serving candidates from coordinator-level through senior management. Philadelphia, Pittsburgh, and King of Prussia are the primary hiring hubs, anchored by employers such as Penn Medicine, UPMC, and GSK. The most in-demand specialties include oncology trial management, regulatory affairs oversight, and Phase II through IV study coordination. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 97+ Clinical Research Manager jobs






Education
Bachelor's Degree Required or
Combination of relevant education and experience may be considered in lieu of degree experience in related clinical research role Required
Experience
2 years experience in related clinical research role Required
See All 97 Clinical Research Manager Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find JobsClinical Research Manager Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Clinical Research Manager Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
- University of Pennsylvania17

- University of Pittsburgh14

- Thomas Jefferson University & Jefferson Health14

- Penn State Health5

- Temple Health4T
Top Industries Hiring
- Healthcare & Medical Services11
- Education4
- Agriculture & Farming1
- Biotechnology & Pharmaceuticals1
What Pennsylvania Employers Look For
The qualifications that appear most often in clinical research manager jobs across Pennsylvania.
- Bachelor's or master's degree in life sciences, nursing, or a related clinical field
- Minimum five years of clinical research experience with at least two in a supervisory role
- Certified Clinical Research Professional (CCRP) or equivalent credential strongly preferred
- Demonstrated experience managing ICH-GCP compliance and FDA regulatory submissions
- Proficiency with electronic data capture systems such as Medidata Rave or Veeva Vault
- Experience overseeing multi-site trial budgets, contracts, and sponsor communications
Clinical Research Manager Jobs in Pennsylvania: Frequently Asked Questions
How do you become a clinical research manager in Pennsylvania?
The most direct path is a bachelor's degree in a life science, nursing, or health-related field followed by several years of hands-on clinical research coordination experience. Pennsylvania does not require a state-issued license to manage clinical trials, but most employers expect certification through the Society of Clinical Research Associates (SOCRA) or the Association of Clinical Research Professionals (ACRP). Large academic medical centers and pharmaceutical employers in the Philadelphia corridor typically require demonstrated GCP training and trial management experience before promoting into a manager role.
Which companies hire clinical research managers in Pennsylvania?
Employers hiring clinical research managers in Pennsylvania right now include University of Pennsylvania, University of Pittsburgh, and Thomas Jefferson University & Jefferson Health, based on current listings on Migrate Mate as of October 2026. Pennsylvania's dense concentration of health systems and pharmaceutical headquarters along the southeastern corridor means sustained hiring across both sponsor-side and site-side research operations throughout the year.
Which Pennsylvania cities have the most clinical research manager jobs?
Philadelphia, Pittsburgh, and Hershey account for the most clinical research manager openings in Pennsylvania. Philadelphia dominates because of its cluster of academic medical centers, large hospital systems, and major pharmaceutical and biotech employers, while Pittsburgh draws significant volume from UPMC's research enterprise, and suburban markets like King of Prussia benefit from the headquarters and regional offices of several global pharmaceutical companies.
Are there remote clinical research manager jobs in Pennsylvania?
Yes, and more than many clinical roles, because a meaningful portion of the work involves data oversight, vendor management, and regulatory documentation rather than direct patient contact. About 59% of clinical research manager openings tied to Pennsylvania are remote or hybrid as of October 2026, reflecting growing sponsor and CRO flexibility. Sponsor-side and CRO roles tend to offer the most remote options, while site-based positions at hospitals or academic centers typically require on-site presence.
How can I get hired as a clinical research manager in Pennsylvania with little or no experience?
The most realistic entry point is a clinical research coordinator or research associate role at a Pennsylvania academic medical center or health system such as Jefferson Health, Temple Health, or Children's Hospital of Philadelphia, which regularly hire coordinators without prior research management experience. From there, earning an ACRP or SOCRA certification while managing a protocol independently is the clearest route to a manager title. Candidates with adjacent backgrounds in nursing, pharmacy, or regulatory affairs at Pennsylvania-based pharmaceutical companies often make lateral moves that accelerate the path into management.
Where can I find and apply to clinical research manager jobs in Pennsylvania?
You can find and apply to clinical research manager jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings across health systems, pharmaceutical companies, and contract research organizations. Find roles that fit your experience and location and apply directly from the listing.
See All 97 Clinical Research Manager Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Jobs