Scientist Jobs at Amgen with Visa Sponsorship
Scientist jobs at Amgen span drug discovery, translational research, and biologics development across therapeutic areas including oncology, inflammation, and rare disease. Amgen has a strong track record of sponsoring international researchers, making it one of the more accessible large biopharma employers for candidates who need work authorization.
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LOCATION: India - Hyderabad
JOB ID: R-235555
WORK LOCATION TYPE: On Site
DATE POSTED: Jun. 05, 2026
CATEGORY: Research
Principal Scientist - Pharmacokinetics and Drug Metabolism (Small molecule In vitro ADME group lead)
What you will do
Let’s do this. Let’s change the world. In this role we are seeking a highly motivated scientist to lead a group of in vitro ADME scientists in Pharmacokinetics and Drug Metabolism (PKDM) team at our upcoming research facility in India. The successful candidate will bring strong hands-on expertise in in vitro ADME assays, high-throughput screening, and a strong desire to involve in mechanistic ADME assay development to support small molecule drug discovery projects. This role requires both scientific excellence and team management skills to foster collaboration, innovation, and operational efficiency. In this role, your core responsibilities include:
- Involve and mentor a team of scientists in the design, execution, and interpretation of in vitro ADME studies
- Develop, optimize, validate, and implement mechanistic in vitro assays to characterize drug metabolism, transporter interactions, and drug–drug interaction (DDI) risk
- Design, establish, and validate robust high-throughput screening workflows to support compound profiling and lead optimization efforts
- Oversee the execution and interpretation of a comprehensive suite of in vitro ADME assays, including:
- Metabolic stability assessments using liver microsomes, S9 fractions, and hepatocytes
- Binding assays
- CYP450 inhibition and induction studies
- Transporter uptake and efflux assays
- In vitro drug–drug interaction (DDI) evaluations
- Manage and maintain cell culture platforms supporting ADME studies, including primary hepatocytes, immortalized cell lines, and transporter-transfected cell systems, ensuring model suitability and reproducibility
- Supervise permeability and absorption studies using established in vitro models to assess compound absorption potential
- Ensure data quality, integrity, reproducibility, and timely delivery of results across all in vitro ADME activities, in alignment with internal standards and project timelines
- Ensure compliance with applicable regulatory guidelines, safety requirements, and internal quality systems, maintaining thorough and audit-ready documentation
- Develop team members, fostering a culture of scientific rigor, continuous improvement, and innovation
PREFERRED QUALIFICATIONS:
- PhD or Masters with 12+ Years in Pharmacokinetics, Pharmaceutical Sciences, or related fields
- Strong hands-on experience in developing mechanistic in vitro ADME models (e.g. enzyme kinetics, DDI and transporter assays etc) and interpreting complex datasets
- Proven track record in high-throughput screening and assay automation
- Team management skills
- Excellent communication, collaboration, and problem-solving abilities
- Strong publication or project track record in ADME/DMPK research is a plus
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Get Access To All JobsTips for Finding Scientist Jobs at Amgen
Align your credentials to Amgen's pipeline focus
Amgen prioritizes scientists with expertise in biologics, antibody engineering, or translational medicine. Frame your CV around techniques and therapeutic areas that map directly to their active pipeline, not general lab skills.
Distinguish your visa type early in applications
Amgen sponsors multiple visa categories for Scientists. Clarifying upfront whether you need H-1B, E-3, or TN sponsorship saves time and signals self-awareness. Recruiters at large biopharma firms deal with mixed applicant pools and appreciate candidates who know their own situation.
Search verified Scientist openings on Migrate Mate
Amgen lists Scientist roles across multiple sites and levels. Use Migrate Mate to filter specifically for positions that have confirmed visa sponsorship, so you're targeting openings before recruiters close the pipeline.
Prepare your degree equivalency documentation in advance
Amgen's Scientist roles typically require a Ph.D. or a master's degree plus industry experience. If your degree was awarded outside the U.S., get a credential evaluation from a NACES-member organization before you reach the offer stage, as USCIS requires this for H-1B specialty occupation petitions.
Understand Amgen's PERM timeline for immigrant visas
If you're targeting a long-term path to a Green Card, ask your recruiter whether Amgen initiates PERM for Scientist-level roles. DOL's PERM process can take 12 to 18 months before I-140 filing, so knowing the employer's standard practice helps you plan your status extensions.
Use OPT STEM extension time strategically during hiring
F-1 students on STEM OPT have up to 36 months of work authorization, which covers two H-1B lottery cycles. Amgen's Scientist hiring often runs through postdoctoral pipelines, so entering the interview process early in your OPT period gives you a realistic runway to secure H-1B sponsorship.
Frequently Asked Questions
Does Amgen sponsor H-1B visas for Scientists?
Yes, Amgen sponsors H-1B visas for Scientist roles. The company has a well-established immigration program and regularly files H-1B petitions for research and development positions across its U.S. sites, including Thousand Oaks, South San Francisco, and Cambridge. Scientist roles typically qualify as specialty occupations under USCIS criteria given the degree requirements involved.
How do I apply for Scientist jobs at Amgen?
Applications go through Amgen's careers portal. Scientist roles range from entry-level to principal, so filter by your degree level and therapeutic area focus. You can also browse open Scientist positions at Amgen that have confirmed visa sponsorship on Migrate Mate, which surfaces roles specifically relevant to candidates who need work authorization.
Which visa types does Amgen commonly use for Scientist roles?
Amgen sponsors H-1B, E-3 visa, TN visa, J-1 visa, and F-1 OPT and CPT for Scientist positions, as well as employment-based immigrant visas including EB-2 and EB-3 for longer-term hires. The appropriate visa depends on your citizenship and degree level. Australian citizens are eligible for E-3 visa, while Canadian and Mexican nationals in qualifying scientific roles may use TN visa status.
What qualifications does Amgen expect for Scientist roles?
Most Scientist openings at Amgen require a Ph.D. in a relevant life sciences discipline, such as biochemistry, molecular biology, immunology, or pharmacology. Some mid-level roles accept a master's degree with several years of industry experience. Hands-on expertise in biologics characterization, cell-based assays, or in vivo models is frequently listed as a core requirement rather than a preference.
How do I time my job search if I'm on OPT or awaiting an H-1B decision?
If you're on F-1 OPT, target Amgen's Scientist openings at least three to four months before your OPT expires to allow time for onboarding and H-1B cap filing, which USCIS opens in March for an October 1 start date. STEM OPT extensions give you additional runway if your first lottery attempt is unsuccessful. Confirm early in the interview process whether your role qualifies for cap-exempt filing through any affiliated research entity.