Manufacturing Engineer Jobs at Amgen with Visa Sponsorship
Manufacturing Engineer jobs at Amgen sit at the intersection of biotech science and large-scale production, covering process development, GMP compliance, and biologics manufacturing. Amgen has a consistent track record of sponsoring international engineers across multiple visa categories, making it a realistic target for qualified candidates who need work authorization.
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Information Systems
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease – we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.
Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Senior Manufacturing Systems Engineer – Manufacturing Systems and Integrated Technologies
What you will do
Let’s do this. Let’s change the world. In this vital role, you will be a part of our Clinical and Commercial Manufacturing Operations Technology team, driving the operation, refinement, and integration of cutting-edge manufacturing applications. This role is an excellent opportunity to gain an understanding of Amgen’s key manufacturing systems, working with various MCS (Manufacturing and Clinical Supply) business partners to ensure products to patients by managing and supporting key computerized systems such as MES (Manufacturing Execution System), Clinical Label Printing and Packaging, PI Data Historian, Instrument Data Acquisition (IDA) and other integrated systems.
As a member of our team, you'll be the driving force behind our mission to deliver high-quality products efficiently and effectively. This role will be responsible for managing the MES platform and associated integrations for the ATO site. In addition to supporting key manufacturing operations, you will work closely with the Global Instrument Data Acquisition (IDA) team to drive a Global MES Standardization effort across all Amgen manufacturing locations. This includes ensuring seamless integration of instrument data, implementing standardized MES processes and protocols, and collaborating with global stakeholders to align best practices and compliance requirements. Your efforts will be critical in optimizing manufacturing systems, enhancing data integrity, and promoting consistency and efficiency across Amgen’s worldwide network.
You'll collaborate closely with cross-functional teams, site business leads, and plant leads that include Manufacturing, Supply Chain, Quality, MCS Engineering, Enterprise Architects, and MES/IDA Global Teams to ensure seamless implementation and optimization of MES, PI Historian Systems, and support partnering with MCS automation/engineering teams for GLAM project support.
The role will be part of the Site Operations Technology team which is responsible for delivering systems in support of Clinical and Commercial Manufacturing, working in a client-facing ATO site-focused approach.
Responsibilities:
- Support key TCT manufacturing systems by driving operational stability and continuous improvements across Building 7, B20, B23, and the ATO site.
- Manage key system integrations, both existing and new, to streamline manufacturing operations.
- Champion business process improvements and support strategic digital initiatives by leveraging established platforms, city plan technology, and artificial intelligence applications.
- Provide on-call support, including after-hours escalations and troubleshooting for operations technology application issues, aligned with 24x7 manufacturing requirements at the ATO site.
- Lead major incident and problem investigations, including root cause analysis, deviation investigations, corrective actions, and 5-why analysis.
- Ensure compliance by maintaining and updating inspection readiness for critical applications, including inspection playbooks, periodic assessments for data integrity, security, and system compliance, and SDLC validation and testing.
- Support regulatory inspections by providing data, delivering presentations on site systems and technology processes, and collaborating with subject matter experts as needed.
- Lead initiatives to introduce Industry 4.0 technologies to improve manufacturing efficiency and capacity.
- Lead and train team members to support operational excellence and develop multi-system competencies.
- Support and lead CMDB updates and system health, ensuring accurate and up-to-date configuration data in partnership with service owners and managers.
- Support the assessment of impactful changes during weekly ATO Change Advisory Board (CAB) meetings.
- Support Amgen’s cyber resiliency efforts, including Sentinels and ECR Network initiatives.
- Provide on-site, client-facing support at the ATO site up to five days per week, based on business needs.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.
Basic Qualifications:
Doctorate degree
OR
Master’s degree and 2 years of Information Systems/Systems Engineering experience
OR
Bachelor’s degree and 4 years of Information Systems/Systems Engineering experience
OR
Associate’s degree and 8 years of Information Systems/Systems Engineering experience
OR
High school diploma / GED and 10 years of Information Systems/Systems Engineering experience
Preferred Qualifications:
- BS/MS degree in Information Systems, Computer Science, Engineering, or the Life Sciences.
- 5+ years’ experience in the biotech/pharmaceutical industry and working with GxP computer systems in a regulated environment.
- Experience with Amgen Technology Systems support and validation.
- Database skills (queries, stored procedures, reports).
- Experience with CDOCS, Application Lifecycle Management (ALM).
- Strong history of analytical and troubleshooting skills.
- Experience with ISM/AmgenNow is preferred.
- Work experience within biotechnology, pharmaceutical, or healthcare.
- Strong leadership/consultative, collaboration, project management, service delivery, and process improvement skills to facilitate alignment across multiple stakeholder groups.
- Strong experience in systems analysis. Ability to work with business clients to understand their business processes, manage scope of work/expectations, and suggest/recommend IS solutions.
- Experience leading the IS change control process and building, validating, and supporting GxP systems.
- Strong written, presentation, and verbal communication skills and technical expertise to be able to communicate effectively with business and technology partners.
- Organization, with proven ability to quickly learn new concepts and technologies and prioritize outcomes.
- Experience in technical writing and performing root cause analysis of incidents/deviations and handling CAPA.
What you can expect from us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies
Apply now and make a lasting impact with the Amgen team.
Salary Range
147,421.00 USD - 177,467.00 USD
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Career Category
Information Systems
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease – we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.
Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Senior Manufacturing Systems Engineer – Manufacturing Systems and Integrated Technologies
What you will do
Let’s do this. Let’s change the world. In this vital role, you will be a part of our Clinical and Commercial Manufacturing Operations Technology team, driving the operation, refinement, and integration of cutting-edge manufacturing applications. This role is an excellent opportunity to gain an understanding of Amgen’s key manufacturing systems, working with various MCS (Manufacturing and Clinical Supply) business partners to ensure products to patients by managing and supporting key computerized systems such as MES (Manufacturing Execution System), Clinical Label Printing and Packaging, PI Data Historian, Instrument Data Acquisition (IDA) and other integrated systems.
As a member of our team, you'll be the driving force behind our mission to deliver high-quality products efficiently and effectively. This role will be responsible for managing the MES platform and associated integrations for the ATO site. In addition to supporting key manufacturing operations, you will work closely with the Global Instrument Data Acquisition (IDA) team to drive a Global MES Standardization effort across all Amgen manufacturing locations. This includes ensuring seamless integration of instrument data, implementing standardized MES processes and protocols, and collaborating with global stakeholders to align best practices and compliance requirements. Your efforts will be critical in optimizing manufacturing systems, enhancing data integrity, and promoting consistency and efficiency across Amgen’s worldwide network.
You'll collaborate closely with cross-functional teams, site business leads, and plant leads that include Manufacturing, Supply Chain, Quality, MCS Engineering, Enterprise Architects, and MES/IDA Global Teams to ensure seamless implementation and optimization of MES, PI Historian Systems, and support partnering with MCS automation/engineering teams for GLAM project support.
The role will be part of the Site Operations Technology team which is responsible for delivering systems in support of Clinical and Commercial Manufacturing, working in a client-facing ATO site-focused approach.
Responsibilities:
- Support key TCT manufacturing systems by driving operational stability and continuous improvements across Building 7, B20, B23, and the ATO site.
- Manage key system integrations, both existing and new, to streamline manufacturing operations.
- Champion business process improvements and support strategic digital initiatives by leveraging established platforms, city plan technology, and artificial intelligence applications.
- Provide on-call support, including after-hours escalations and troubleshooting for operations technology application issues, aligned with 24x7 manufacturing requirements at the ATO site.
- Lead major incident and problem investigations, including root cause analysis, deviation investigations, corrective actions, and 5-why analysis.
- Ensure compliance by maintaining and updating inspection readiness for critical applications, including inspection playbooks, periodic assessments for data integrity, security, and system compliance, and SDLC validation and testing.
- Support regulatory inspections by providing data, delivering presentations on site systems and technology processes, and collaborating with subject matter experts as needed.
- Lead initiatives to introduce Industry 4.0 technologies to improve manufacturing efficiency and capacity.
- Lead and train team members to support operational excellence and develop multi-system competencies.
- Support and lead CMDB updates and system health, ensuring accurate and up-to-date configuration data in partnership with service owners and managers.
- Support the assessment of impactful changes during weekly ATO Change Advisory Board (CAB) meetings.
- Support Amgen’s cyber resiliency efforts, including Sentinels and ECR Network initiatives.
- Provide on-site, client-facing support at the ATO site up to five days per week, based on business needs.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.
Basic Qualifications:
Doctorate degree
OR
Master’s degree and 2 years of Information Systems/Systems Engineering experience
OR
Bachelor’s degree and 4 years of Information Systems/Systems Engineering experience
OR
Associate’s degree and 8 years of Information Systems/Systems Engineering experience
OR
High school diploma / GED and 10 years of Information Systems/Systems Engineering experience
Preferred Qualifications:
- BS/MS degree in Information Systems, Computer Science, Engineering, or the Life Sciences.
- 5+ years’ experience in the biotech/pharmaceutical industry and working with GxP computer systems in a regulated environment.
- Experience with Amgen Technology Systems support and validation.
- Database skills (queries, stored procedures, reports).
- Experience with CDOCS, Application Lifecycle Management (ALM).
- Strong history of analytical and troubleshooting skills.
- Experience with ISM/AmgenNow is preferred.
- Work experience within biotechnology, pharmaceutical, or healthcare.
- Strong leadership/consultative, collaboration, project management, service delivery, and process improvement skills to facilitate alignment across multiple stakeholder groups.
- Strong experience in systems analysis. Ability to work with business clients to understand their business processes, manage scope of work/expectations, and suggest/recommend IS solutions.
- Experience leading the IS change control process and building, validating, and supporting GxP systems.
- Strong written, presentation, and verbal communication skills and technical expertise to be able to communicate effectively with business and technology partners.
- Organization, with proven ability to quickly learn new concepts and technologies and prioritize outcomes.
- Experience in technical writing and performing root cause analysis of incidents/deviations and handling CAPA.
What you can expect from us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies
Apply now and make a lasting impact with the Amgen team.
Salary Range
147,421.00 USD - 177,467.00 USD
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
See all Manufacturing Engineer Jobs at Amgen
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Manufacturing Engineer Jobs at Amgen.
Get Access To All JobsTips for Finding Manufacturing Engineer Jobs at Amgen
Align your credentials to GMP standards
Amgen's manufacturing roles operate under strict FDA Good Manufacturing Practice regulations. Before applying, document any GMP training, bioreactor experience, or cleanroom qualifications explicitly in your resume. Amgen's hiring teams screen for these signals early.
Target Amgen's process development pipeline roles
Amgen posts Manufacturing Engineer openings across drug substance, drug product, and process characterization tracks. Roles tied to biologics scale-up tend to see stronger sponsorship support, so filter your search by site location and therapeutic area to find the best-fit openings.
Request an E-3 LCA before your start date
If you're Australian, confirm with Amgen's immigration team that your Labor Condition Application is filed with DOL and certified before scheduling your consular appointment. LCA certification typically takes seven business days but can lag during peak periods.
Use Migrate Mate to surface Amgen openings by visa type
Filter Manufacturing Engineer roles at Amgen by the visa category you hold, whether that's H-1B, E-3, or F-1 OPT. Migrate Mate surfaces only roles where sponsorship has been confirmed, so you're not guessing about eligibility before you apply.
Prepare for PERM before your third year
Amgen routinely supports green card sponsorship for engineers on long-term tracks. If you're on an H-1B, discuss PERM initiation with your manager before your second year ends. DOL's PERM process can take 12 to 18 months, and early filing protects your priority date.
Negotiate OPT start timing around Amgen's onboarding cycles
Amgen's manufacturing sites typically onboard engineers on a quarterly schedule. If you're on F-1 OPT, coordinate your OPT start date with your DSO so your work authorization window aligns with Amgen's actual start date, not just the offer date.
Frequently Asked Questions
Does Amgen sponsor H-1B visas for Manufacturing Engineers?
Yes, Amgen sponsors H-1B visas for Manufacturing Engineer roles. The company files H-1B petitions on behalf of qualifying international candidates and has done so consistently across its U.S. manufacturing sites. If you're in the H-1B lottery pool or seeking a transfer from a current H-1B visa employer, Amgen is an active sponsor for this function.
How do I apply for Manufacturing Engineer jobs at Amgen?
Apply directly through Amgen's careers portal at amgen.com/careers. Search by job function, site location, or business unit to find active Manufacturing Engineer openings. You can also browse confirmed sponsorship roles on Migrate Mate, which filters Amgen listings by visa type so you can identify the positions most relevant to your work authorization status before submitting an application.
Which visa types does Amgen commonly use for Manufacturing Engineer roles?
Amgen sponsors a range of visa categories for Manufacturing Engineers, including H-1B, E-3 visa (for Australian citizens), TN visa (for Canadian and Mexican nationals), F-1 OPT and CPT for students, J-1 visa for exchange visitors, and employment-based Green Card pathways including EB-2 and EB-3. The right category depends on your citizenship, degree level, and career stage.
What qualifications does Amgen expect for Manufacturing Engineer positions?
Most Manufacturing Engineer roles at Amgen require a bachelor's degree in chemical engineering, bioengineering, or a related field, with direct experience in GMP environments. Familiarity with biologics manufacturing, process characterization, or technology transfer is a strong differentiator. Senior roles typically expect hands-on experience with upstream or downstream bioprocessing at commercial scale.
How do I handle visa timing if I receive an offer from Amgen?
Timing depends on your current visa category. H-1B transfers can begin on the filing receipt date, so you can start work without waiting for approval. For E-3 and TN visas, consular processing typically takes two to four weeks once your employer files the required documentation. USCIS premium processing is available for H-1B petitions if you need a faster decision, usually within 15 business days.