ICU Registered Nurse Jobs in South Carolina
ICU Registered Nurse jobs in South Carolina are in strong and consistent demand, concentrated across major hospital systems, academic medical centers, and regional trauma facilities serving a growing state population. The heaviest hiring is in Columbia, Greenville, and Charleston, where large health systems like MUSC Health, Prisma Health, and Bon Secours St. Francis Health System anchor the market at every level from new graduate to senior charge nurse. Critical care subspecialties including cardiac ICU, surgical ICU, and neuro ICU see the most consistent openings. See the openings below and apply to the ones that match your experience.
Find ICU Registered Nurse JobsOverview
Showing 5 of 53+ ICU Registered Nurse jobs
SIGN ON BONUS $5,000.00 New Grad - $10,000.00 Eligible Experienced RN
Our Intensive Care Unit has 18 beds and utilizes latest technology such as Omnicell, Epic, and Mindray (for vitals), allowing our team to provide the best care possible to our patients. Our Nurse-to-Patient Ratio is 1:2 or 1:3 depending upon acuity. We work with medical and surgical ICU cases, single system organ failure, diabetic ketoacidosis, sepsis, CHS, COPD, etc. This team has excellent comradery and is often recognized for their superb clinical skill set.
The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and Values. Associates are encouraged to engage and support Spartanburg Regional Healthcare System's involvement in the communities we serve.
Minimum Requirements
Education
- Graduate of an approved / accredited School of Nursing
Experience
- Novice to expert nurse
License/Registration/Certifications
- Current RN licensure in the State of South Carolina or Compact State
- BLS - may secure certification post-hire
Preferred Requirements
Preferred Experience
- One Year of Recent RN experience within the past 5 years
Core Job Responsibilities
- Basic computer skills
- Demonstrates competency utilizing electronic health record
- Documents all aspects of patient care by following established charting procedure to show the patient's progress or any change in the patient's condition
- Adheres to system required standards of behavior
- Adheres to proper chain of command
- Meets continuing education requirements, demonstrates knowledge of and ensures compliance with clinical expectations of regulatory agency requirements (DNV, DHEC, CMS)
- Effectively communicates with patients, families, providers, and hospital associates
- Knowledgeable in use of and response to Facility Alert, Medical Alert, Medical Emergency Systems
- Develops, implements, evaluates, and revises plan of care based on physical, psychosocial, spiritual, and educational needs of the patient/family
- Provides a safe patient care environment
- Collaborates with patient, families, and other members of the health care team to determine patient priorities, treatments
- Coordinates, provides, and directs patient teaching activities
- Initiates and facilitates interdisciplinary collaboration to enhance outcome
- Seeks necessary assistance in completing nursing interventions to assure positive patient outcomes
- Responsible for demonstrating competencies for new equipment, procedures, and annual competency validation
- Provides clinical guidance to students and ancillary staff
- Successfully completes hospital and unit-based orientation programs and annual competencies
- Formulates a plan for personal professional growth
- Recommends the need to develop or revise policies and procedures
- Serves on unit-based committees and as assigned
- Prioritizes nursing interventions for an assigned group of patients
- Critically assesses assigned patients' medical history, admitting diagnosis and physician's orders, obtains nursing history, performs physical assessment, evaluates diagnostic data, and interviews patient and family to determine patient needs
- Ability to properly assess and prioritize multiple patients according to the severity of illness, injury, and/or needs
- Able to assess, critically think, and provide quality patient care inherent to the fast-paced, dynamic environment
- Professionally interact and communicate with patients from all age groups, diverse backgrounds, and varying educational levels. Also, must be able to communicate and treat patients that may be confused, irrational, agitated, and/or uncooperative
- Utilizes Nursing standards and protocols to manage and stabilize emergencies until provider responds
- Demonstrates knowledge of professional nursing practice and theory
- Assures continuity of care through effective decision making resulting in quality patient care
- Remains committed to unit, department, and division goals
- Support patient experience initiatives
- Participates in purposeful rounding, bedside shift reports, and huddles
- Demonstrates knowledge and ensures compliance with clinical expectations regarding regulatory agency requirements (DNV, DHEC, CMS)
- Demonstrates appropriate standards of care, clinical pathways, and milestones to drive the plan of care
- Complies with current policies and procedures
- Other duties as assigned
SIGN ON BONUS $5,000.00 New Grad - $10,000.00 Eligible Experienced RN
Our Intensive Care Unit has 18 beds and utilizes latest technology such as Omnicell, Epic, and Mindray (for vitals), allowing our team to provide the best care possible to our patients. Our Nurse-to-Patient Ratio is 1:2 or 1:3 depending upon acuity. We work with medical and surgical ICU cases, single system organ failure, diabetic ketoacidosis, sepsis, CHS, COPD, etc. This team has excellent comradery and is often recognized for their superb clinical skill set.
The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and Values. Associates are encouraged to engage and support Spartanburg Regional Healthcare System's involvement in the communities we serve.
Minimum Requirements
Education
- Graduate of an approved / accredited School of Nursing
Experience
- Novice to expert nurse
License/Registration/Certifications
- Current RN licensure in the State of South Carolina or Compact State
- BLS - may secure certification post-hire
Preferred Requirements
Preferred Experience
- One Year of Recent RN experience within the past 5 years
Core Job Responsibilities
- Basic computer skills
- Demonstrates competency utilizing electronic health record
- Documents all aspects of patient care by following established charting procedure to show the patient's progress or any change in the patient's condition
- Adheres to system required standards of behavior
- Adheres to proper chain of command
- Meets continuing education requirements, demonstrates knowledge of and ensures compliance with clinical expectations of regulatory agency requirements (DNV, DHEC, CMS)
- Effectively communicates with patients, families, providers, and hospital associates
- Knowledgeable in use of and response to Facility Alert, Medical Alert, Medical Emergency Systems
- Develops, implements, evaluates, and revises plan of care based on physical, psychosocial, spiritual, and educational needs of the patient/family
- Provides a safe patient care environment
- Collaborates with patient, families, and other members of the health care team to determine patient priorities, treatments
- Coordinates, provides, and directs patient teaching activities
- Initiates and facilitates interdisciplinary collaboration to enhance outcome
- Seeks necessary assistance in completing nursing interventions to assure positive patient outcomes
- Responsible for demonstrating competencies for new equipment, procedures, and annual competency validation
- Provides clinical guidance to students and ancillary staff
- Successfully completes hospital and unit-based orientation programs and annual competencies
- Formulates a plan for personal professional growth
- Recommends the need to develop or revise policies and procedures
- Serves on unit-based committees and as assigned
- Prioritizes nursing interventions for an assigned group of patients
- Critically assesses assigned patients' medical history, admitting diagnosis and physician's orders, obtains nursing history, performs physical assessment, evaluates diagnostic data, and interviews patient and family to determine patient needs
- Ability to properly assess and prioritize multiple patients according to the severity of illness, injury, and/or needs
- Able to assess, critically think, and provide quality patient care inherent to the fast-paced, dynamic environment
- Professionally interact and communicate with patients from all age groups, diverse backgrounds, and varying educational levels. Also, must be able to communicate and treat patients that may be confused, irrational, agitated, and/or uncooperative
- Utilizes Nursing standards and protocols to manage and stabilize emergencies until provider responds
- Demonstrates knowledge of professional nursing practice and theory
- Assures continuity of care through effective decision making resulting in quality patient care
- Remains committed to unit, department, and division goals
- Support patient experience initiatives
- Participates in purposeful rounding, bedside shift reports, and huddles
- Demonstrates knowledge and ensures compliance with clinical expectations regarding regulatory agency requirements (DNV, DHEC, CMS)
- Demonstrates appropriate standards of care, clinical pathways, and milestones to drive the plan of care
- Complies with current policies and procedures
- Other duties as assigned
See All 53 ICU Registered Nurse Jobs in South Carolina
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Find ICU Registered Nurse JobsICU Registered Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
ICU Registered Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Prisma Health13
- ATC Healthcare6
- Lexington Health6
- American Traveler6
- Tenet Healthcare5
Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in ICU registered nurse jobs across South Carolina.
- Active South Carolina RN license or multistate Compact license recognized in South Carolina
- Current BLS and ACLS certification required for all ICU positions
- Minimum one to two years of acute care or critical care nursing experience
- Bachelor of Science in Nursing preferred or required by most major health systems
- Proficiency with mechanical ventilators, hemodynamic monitoring, and vasoactive drips
- CCRN certification preferred and often required for senior or charge nurse roles
ICU Registered Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a icu registered nurse in South Carolina?
You must hold an active registered nurse license issued or recognized by the South Carolina Board of Nursing, which requires passing the NCLEX-RN after completing an accredited nursing program. To work specifically in an ICU, most South Carolina hospitals require or strongly prefer at least one year of acute care experience, often gained in a med-surg or step-down unit, before transitioning to critical care. Completing a critical care internship offered by larger systems like Prisma Health or MUSC Health can replace that prior experience requirement for new graduates.
How much do ICU registered nurses make in South Carolina?
ICU registered nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire icu registered nurses in South Carolina?
Employers hiring icu registered nurses in South Carolina right now include Prisma Health, ATC Healthcare, and Lexington Health, based on current listings on Migrate Mate as of October 2026. South Carolina's largest academic medical systems and regional hospital networks consistently drive the majority of ICU nursing openings across the state.
Which South Carolina cities have the most icu registered nurse jobs?
West Columbia, Charleston, and Aiken lead South Carolina in icu registered nurse openings. Columbia's concentration of large teaching hospitals and Prisma Health's flagship campus drives high volume there, Charleston's openings reflect MUSC Health's academic medical center and growing coastal population, and Greenville's market is anchored by Prisma Health Greenville Memorial and the Bon Secours St. Francis system serving the upstate region.
How can I get hired as a icu registered nurse in South Carolina with little or no experience?
The most realistic path is applying directly to new graduate critical care residency programs, which MUSC Health, Prisma Health, and Bon Secours St. Francis run specifically to train nurses for ICU roles without prior critical care experience. Starting in a step-down or progressive care unit at a South Carolina community hospital is a strong alternative entry point. Holding an active South Carolina RN license, completing ACLS certification before applying, and demonstrating clinical hours in acute care settings during nursing school will all strengthen your candidacy significantly.
Where can I find and apply to icu registered nurse jobs in South Carolina?
You can find and apply to icu registered nurse jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, find the positions that match your experience and preferred location, and apply directly to the ones that fit.
See All 53 ICU Registered Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find ICU Registered Nurse Jobs