ICU Registered Nurse Jobs in South Carolina
ICU Registered Nurse jobs in South Carolina are in strong and consistent demand, concentrated across major hospital systems, academic medical centers, and regional trauma facilities serving a growing state population. The heaviest hiring is in Columbia, Greenville, and Charleston, where large health systems like MUSC Health, Prisma Health, and Bon Secours St. Francis Health System anchor the market at every level from new graduate to senior charge nurse. Critical care subspecialties including cardiac ICU, surgical ICU, and neuro ICU see the most consistent openings. See the openings below and apply to the ones that match your experience.
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Join Our High-Performing ICU Team – Where Expertise is Respected and Growth is Encouraged
Location: Pelham Medical Center
Unit: Intensive Care Unit (ICU) – 4-Bed, State-of-the-Art Critical Care
Are you an experienced ICU nurse looking for a team that matches your clinical excellence, values your insight, and invests in your professional development?
At Pelham Medical Center, our ICU isn’t just equipped with advanced technology—it’s built around a strong culture of collaboration, autonomy, and exceptional patient care. With a 1:2 nurse-to-patient ratio, modern accommodations, and a highly engaged team of clinicians, this is an environment where skilled nurses can thrive.
Why Experienced ICU Nurses Choose Pelham Medical Center
- Advanced Equipment in Every Room: Our ICU rooms are equipped for efficiency and rapid response, including the latest LUCAS device, SiteRite Ultrasound, PreVue, and Glidescope/Glidescope Go systems.
- Team-Driven Care: Work alongside a tight-knit, interdisciplinary team that values your experience and voice. We believe high-quality care happens when nurses are empowered.
- Meaningful Cases: From major respiratory illnesses to complex cardiac conditions and endocrine disorders, our unit provides the clinical depth and challenge you’re looking for.
- Work-Life Balance: We prioritize well-being and manageable workloads, with processes in place to reduce burnout and optimize your time at the bedside.
- Professional Growth: Whether you're pursuing a clinical ladder, mentoring others, or developing leadership skills, we provide clear pathways and support to help you grow.
Position Highlights
- 4-bed ICU with 2 negative-pressure rooms
- Hemodialysis-ready for all beds
- Strong support staff and integrated multidisciplinary rounds
- Culture rooted in excellence, support, and shared decision-making
What We’re Looking For
Minimum Requirements:
- Graduate of an accredited nursing program
- Current RN licensure in South Carolina or Compact State
- BLS and ACLS (may be obtained after hire)
- Experience: novice to expert nurse
Preferred:
1+ years of ICU or acute critical care experience in the past 5 years- BSN preferred
Your Core Responsibilities Include:
- Providing complex, high-acuity patient care
- Collaborating with physicians, RTs, and support staff to improve patient outcomes
- Using critical thinking and advanced clinical judgment to guide care decisions
- Participating in shared governance, quality improvement, and staff development initiatives
Ready to Use Your Expertise Where It Counts?
If you're a seasoned ICU nurse who wants to make an impact, feel supported, and be surrounded by excellence, we want to meet you.
Apply today and become part of an ICU team where your voice is heard, your skills are valued, and your career is respected.
See All 62 ICU Registered Nurse Jobs in South Carolina
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Find ICU Registered Nurse JobsICU Registered Nurse Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
ICU Registered Nurse Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Prisma Health14

- American Traveler8

- Lexington Health7

- Spartanburg Regional Healthcare System6

- Tenet Healthcare5

Top Industries Hiring
- Healthcare & Medical Services
- Non-Profit & Social Services
What South Carolina Employers Look For
The qualifications that appear most often in ICU registered nurse jobs across South Carolina.
- Active South Carolina RN license or multistate Compact license recognized in South Carolina
- Current BLS and ACLS certification required for all ICU positions
- Minimum one to two years of acute care or critical care nursing experience
- Bachelor of Science in Nursing preferred or required by most major health systems
- Proficiency with mechanical ventilators, hemodynamic monitoring, and vasoactive drips
- CCRN certification preferred and often required for senior or charge nurse roles
ICU Registered Nurse Jobs in South Carolina: Frequently Asked Questions
How do you become a icu registered nurse in South Carolina?
You must hold an active registered nurse license issued or recognized by the South Carolina Board of Nursing, which requires passing the NCLEX-RN after completing an accredited nursing program. To work specifically in an ICU, most South Carolina hospitals require or strongly prefer at least one year of acute care experience, often gained in a med-surg or step-down unit, before transitioning to critical care. Completing a critical care internship offered by larger systems like Prisma Health or MUSC Health can replace that prior experience requirement for new graduates.
How much do ICU registered nurses make in South Carolina?
ICU registered nurses in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire icu registered nurses in South Carolina?
Employers hiring icu registered nurses in South Carolina right now include Prisma Health, American Traveler, and Lexington Health, based on current listings on Migrate Mate as of August 2026. South Carolina's largest academic medical systems and regional hospital networks consistently drive the majority of ICU nursing openings across the state.
Which South Carolina cities have the most icu registered nurse jobs?
Columbia, Rock Hill, and West Columbia lead South Carolina in icu registered nurse openings. Columbia's concentration of large teaching hospitals and Prisma Health's flagship campus drives high volume there, Charleston's openings reflect MUSC Health's academic medical center and growing coastal population, and Greenville's market is anchored by Prisma Health Greenville Memorial and the Bon Secours St. Francis system serving the upstate region.
Are there remote icu registered nurse jobs in South Carolina?
Yes, but they're rare. ICU nursing is a hands-on, bedside role that requires physical presence in a hospital setting, so fully remote positions are uncommon. About 0% of icu registered nurse openings tied to South Carolina are remote or hybrid as of August 2026, and those positions typically involve telehealth triage, remote patient monitoring oversight, or case management functions rather than direct bedside critical care.
How can I get hired as a icu registered nurse in South Carolina with little or no experience?
The most realistic path is applying directly to new graduate critical care residency programs, which MUSC Health, Prisma Health, and Bon Secours St. Francis run specifically to train nurses for ICU roles without prior critical care experience. Starting in a step-down or progressive care unit at a South Carolina community hospital is a strong alternative entry point. Holding an active South Carolina RN license, completing ACLS certification before applying, and demonstrating clinical hours in acute care settings during nursing school will all strengthen your candidacy significantly.
Where can I find and apply to icu registered nurse jobs in South Carolina?
You can find and apply to icu registered nurse jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, find the positions that match your experience and preferred location, and apply directly to the ones that fit.
See All 62 ICU Registered Nurse Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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