Risk Management Analyst Jobs in Pennsylvania
Risk Management Analyst jobs in Pennsylvania are consistently active, with strong demand across financial services, insurance, healthcare, and energy from entry-level associates through senior risk directors. Philadelphia and Pittsburgh anchor most of the hiring, with growing activity in Harrisburg tied to state government and regulated industries, and employers like Comcast, UPMC, and Lincoln Financial Group maintaining a lasting presence here. The most in-demand specialties are enterprise risk management, regulatory compliance, and operational risk for financial institutions. Find a role that fits below and apply directly.
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About the Position
Cabaletta Bio is seeking a Director, Enterprise Risk Management to establish and lead the company's enterprise risk management (ERM) program as we advance toward BLA submission and commercial launch. Reporting to the Chief Compliance Officer, this role will build a structured, company-wide approach to identifying, assessing, mitigating, and monitoring risk across clinical, regulatory, quality, and commercial operations. A core focus of the role is quality risk management across the product lifecycle, including risk-based oversight of the company's external manufacturing network of three CDMOs, ensuring the risk management framework scales with the organization as it prepares for its first product launch.
This is a highly visible, cross-functional role suited to someone who can stand up a program from the ground floor, engage executive leadership and functional heads, and translate risk insights into practical, prioritized action.
Responsibilities Include
Enterprise Risk Management
- Design, implement, and lead the enterprise risk management framework, including governance structure, risk taxonomy, risk appetite statements, and escalation pathways
- Facilitate periodic enterprise risk assessments with executive leadership and functional owners; maintain the corporate risk register and heat maps
- Partner with functional leaders (Clinical, Regulatory, Quality, CMC, Commercial, IT, Finance, Legal) to identify emerging risks, define mitigation plans, and track remediation to closure
- Develop and deliver risk reporting to the executive team and, as appropriate, the Board or Board committees
- Integrate risk management with related programs, including quality risk management (ICH Q9 principles), business continuity, third-party/vendor risk, and inspection readiness
- Monitor the external environment (regulatory enforcement trends, industry events, evolving guidance) and translate implications into the risk program
Quality Risk Management & External Manufacturing Oversight
- Lead the application of quality risk management principles (ICH Q9(R1)) across the product lifecycle, including risk assessments supporting manufacturing, supply chain, and quality operations
- Establish and maintain a risk-based framework for oversight of the company's external manufacturing network, including three CDMOs, spanning vendor risk assessments, ongoing risk monitoring, and periodic risk reviews
- Partner with CMC, Quality, and Supply Chain to assess and manage risks associated with CDMO performance, including deviations, change control, capacity, technology transfer, comparability, and business continuity
- Integrate CDMO and third-party risk into the corporate risk register with clear ownership, mitigation plans, and escalation criteria; ensure risk considerations are reflected in quality agreements and governance forums (e.g., joint steering committees, quality business reviews)
- Support risk-based prioritization of vendor audits and person-in-plant or oversight activities in partnership with GxP Quality Audit
- Ensure risk documentation supporting external manufacturing is inspection-ready and aligned with BLA submission expectations
Program Leadership
- Serve as a trusted advisor to the CCO and functional leadership on risk matters
- Contribute to inspection readiness and BLA-related activities where risk management documentation and governance are in scope
- Build scalable tools, templates, and processes appropriate for a clinical-stage company transitioning to commercial operations
- Potential to build and manage a small team as the function grows
Required Qualifications
- Bachelor's degree in life sciences, business, finance, or related field
- 10+ years of progressive experience in the biopharmaceutical industry, with significant experience in enterprise risk management and quality risk management
- Demonstrated experience designing or leading an ERM program (framework development, risk assessments, risk registers, executive reporting)
- Hands-on experience applying quality risk management (ICH Q9) in a GxP environment, including risk assessments supporting external/contract manufacturing
- Experience managing or overseeing risk across multiple CDMOs or contract manufacturing partners, including vendor risk assessment and governance
- Experience supporting or operating within a pre-launch or newly commercial organization
- Strong facilitation, analytical, and communication skills; able to engage credibly with executives and functional experts alike
- Comfort with ambiguity and a hands-on, roll-up-your-sleeves orientation appropriate for a clinical-stage company
Preferred Qualifications
- Advanced degree (MBA, MS) or relevant certification (e.g., CRMP, ARM, CQA)
- Experience in cell and gene therapy, rare disease, or other specialty/complex products
- Experience with cell therapy or viral vector external manufacturing networks and associated supply chain risk
- Experience presenting to boards or board committees
How to Apply
Please click the link at the bottom of the posting to submit an application.
Benefits
Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.
Equal Opportunity Employer
Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.
About the Position
Cabaletta Bio is seeking a Director, Enterprise Risk Management to establish and lead the company's enterprise risk management (ERM) program as we advance toward BLA submission and commercial launch. Reporting to the Chief Compliance Officer, this role will build a structured, company-wide approach to identifying, assessing, mitigating, and monitoring risk across clinical, regulatory, quality, and commercial operations. A core focus of the role is quality risk management across the product lifecycle, including risk-based oversight of the company's external manufacturing network of three CDMOs, ensuring the risk management framework scales with the organization as it prepares for its first product launch.
This is a highly visible, cross-functional role suited to someone who can stand up a program from the ground floor, engage executive leadership and functional heads, and translate risk insights into practical, prioritized action.
Responsibilities Include
Enterprise Risk Management
- Design, implement, and lead the enterprise risk management framework, including governance structure, risk taxonomy, risk appetite statements, and escalation pathways
- Facilitate periodic enterprise risk assessments with executive leadership and functional owners; maintain the corporate risk register and heat maps
- Partner with functional leaders (Clinical, Regulatory, Quality, CMC, Commercial, IT, Finance, Legal) to identify emerging risks, define mitigation plans, and track remediation to closure
- Develop and deliver risk reporting to the executive team and, as appropriate, the Board or Board committees
- Integrate risk management with related programs, including quality risk management (ICH Q9 principles), business continuity, third-party/vendor risk, and inspection readiness
- Monitor the external environment (regulatory enforcement trends, industry events, evolving guidance) and translate implications into the risk program
Quality Risk Management & External Manufacturing Oversight
- Lead the application of quality risk management principles (ICH Q9(R1)) across the product lifecycle, including risk assessments supporting manufacturing, supply chain, and quality operations
- Establish and maintain a risk-based framework for oversight of the company's external manufacturing network, including three CDMOs, spanning vendor risk assessments, ongoing risk monitoring, and periodic risk reviews
- Partner with CMC, Quality, and Supply Chain to assess and manage risks associated with CDMO performance, including deviations, change control, capacity, technology transfer, comparability, and business continuity
- Integrate CDMO and third-party risk into the corporate risk register with clear ownership, mitigation plans, and escalation criteria; ensure risk considerations are reflected in quality agreements and governance forums (e.g., joint steering committees, quality business reviews)
- Support risk-based prioritization of vendor audits and person-in-plant or oversight activities in partnership with GxP Quality Audit
- Ensure risk documentation supporting external manufacturing is inspection-ready and aligned with BLA submission expectations
Program Leadership
- Serve as a trusted advisor to the CCO and functional leadership on risk matters
- Contribute to inspection readiness and BLA-related activities where risk management documentation and governance are in scope
- Build scalable tools, templates, and processes appropriate for a clinical-stage company transitioning to commercial operations
- Potential to build and manage a small team as the function grows
Required Qualifications
- Bachelor's degree in life sciences, business, finance, or related field
- 10+ years of progressive experience in the biopharmaceutical industry, with significant experience in enterprise risk management and quality risk management
- Demonstrated experience designing or leading an ERM program (framework development, risk assessments, risk registers, executive reporting)
- Hands-on experience applying quality risk management (ICH Q9) in a GxP environment, including risk assessments supporting external/contract manufacturing
- Experience managing or overseeing risk across multiple CDMOs or contract manufacturing partners, including vendor risk assessment and governance
- Experience supporting or operating within a pre-launch or newly commercial organization
- Strong facilitation, analytical, and communication skills; able to engage credibly with executives and functional experts alike
- Comfort with ambiguity and a hands-on, roll-up-your-sleeves orientation appropriate for a clinical-stage company
Preferred Qualifications
- Advanced degree (MBA, MS) or relevant certification (e.g., CRMP, ARM, CQA)
- Experience in cell and gene therapy, rare disease, or other specialty/complex products
- Experience with cell therapy or viral vector external manufacturing networks and associated supply chain risk
- Experience presenting to boards or board committees
How to Apply
Please click the link at the bottom of the posting to submit an application.
Benefits
Our most important asset is our people and we offer competitive benefits including health and retirement, PTO, and stock option plans.
Equal Opportunity Employer
Cabaletta Bio is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law.
See All 22 Risk Management Analyst Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Risk Management Analyst JobsRisk Management Analyst Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Risk Management Analyst Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Energy
- Science & Research
- Agriculture & Farming
- Technology & Software
What Pennsylvania Employers Look For
The qualifications that appear most often in risk management analyst jobs across Pennsylvania.
- Bachelor's degree in finance, business, economics, or a related quantitative field
- Professional Risk Manager (PRM) or Financial Risk Manager (FRM) certification preferred by most Pennsylvania employers
- Two or more years of experience in risk assessment, audit, or financial analysis
- Proficiency in risk management software and enterprise GRC platforms such as RSA Archer or MetricStream
- Strong working knowledge of regulatory frameworks including federal banking, insurance, and healthcare compliance standards
- Demonstrated ability to prepare written risk reports and present findings to executive stakeholders
Risk Management Analyst Jobs in Pennsylvania: Frequently Asked Questions
How do you become a risk management analyst in Pennsylvania?
Start with a bachelor's degree in finance, economics, business, or a related field, which is the baseline requirement for most Pennsylvania employers. Pennsylvania does not require a state-issued license for risk management analysts, but earning the Financial Risk Manager (FRM) credential from GARP or the Professional Risk Manager (PRM) from PRMIA significantly strengthens your candidacy, particularly with Philadelphia's large financial services firms and Pittsburgh's healthcare and energy employers.
How much do risk management analysts make in Pennsylvania?
Risk management analysts in Pennsylvania earn a median of about $103,040 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $64,700 for the lowest 10% to over $172,820 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire risk management analysts in Pennsylvania?
Employers hiring risk management analysts in Pennsylvania right now include Chubb Insurance, PNC Financial Services, and BNY, based on current listings on Migrate Mate as of August 2026. Pennsylvania's concentration of major insurance carriers, regional banks, hospital systems, and regulated utilities means demand is spread across multiple industries rather than concentrated in a single sector.
Which Pennsylvania cities have the most risk management analyst jobs?
Pittsburgh, Philadelphia, and Pennsylvania have the most risk management analyst openings in Pennsylvania. Philadelphia's density of financial institutions, insurance headquarters, and health systems drives the largest share of listings, while Pittsburgh's strength in healthcare, energy, and banking supports steady demand, and Harrisburg's state government agencies and regulated industries anchor hiring in the central region.
Are there remote risk management analyst jobs in Pennsylvania?
Yes, and more than most fields. Risk management analysis is largely desk-based and document-driven, making it well suited to remote and hybrid arrangements. About 71% of risk management analyst openings tied to Pennsylvania are remote or hybrid as of August 2026, reflecting how widely financial services and insurance employers in the state have adopted flexible work. Roles focused on data modeling, reporting, and regulatory documentation tend to offer the most location flexibility.
How can I get hired as a risk management analyst in Pennsylvania with little or no experience?
The most realistic entry path is starting in a junior analyst, audit associate, or compliance coordinator role at a Pennsylvania financial institution or insurer, then moving laterally into risk. Large employers like UPMC, PNC Bank, and Lincoln Financial Group run structured associate and rotational programs that place new graduates in risk-adjacent functions. Pursuing the FRM or PRM certification while in an entry role and building experience with Excel-based modeling and regulatory reporting will accelerate your path to a dedicated risk management analyst position.
Where can I find and apply to risk management analyst jobs in Pennsylvania?
You can find and apply to risk management analyst jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings across financial services, healthcare, insurance, and other industries. Find the roles that fit your experience and location preferences and apply directly to the employers posting them.
See All 22 Risk Management Analyst Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
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