Senior Data Science Engineer Jobs in Minnesota

Senior Data Science Engineer jobs in Minnesota are in strong demand, concentrated in financial services, healthcare technology, retail analytics, and enterprise software, with openings at every senior level from lead individual contributor to principal engineer. The Twin Cities metro anchors most of the hiring, with additional activity in Rochester and Bloomington, where employers such as UnitedHealth Group, Target, and Mayo Clinic have established data science practices. The most sought-after specialties include machine learning infrastructure, MLOps, and large-scale predictive modeling. Find a role that fits below and apply directly.

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Overview

Open roles16
Top employerMayo Clinic
Top cityMinneapolis, MN
Cities hiring8
Work type88% Hybrid
Top industryEducation

Showing 4 of 16+ Senior Data Science Engineer jobs

IDeaS
Data Science Research Internship
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IDeaS
Added 1d ago
Data Science Research Internship
IDeaS
Bloomington, Minnesota
Business Development
Growth Marketing
Marketing
Hybrid
11-50

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Optum
Sr Director Data Science - Remote
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Optum
Added 1w ago
Sr Director Data Science - Remote
Optum
Eden Prairie, Minnesota
Business Strategy
Executive Leadership & C-Suite
Product Management
$159k - $273k/yr
Hybrid
Six Sigma Certification
10,000+

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University of Minnesota
Postdoctoral Research Associate: AI, Data Science, and Intelligent Sensing for Agricultural, Food, and Sustainable Systems (SAGE Lab)
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University of Minnesota
Added 1w ago
Postdoctoral Research Associate: AI, Data Science, and Intelligent Sensing for Agricultural, Food, and Sustainable Systems (SAGE Lab)
University of Minnesota
Minneapolis, Minnesota
Biotech & Life Sciences
Engineering (Non-Software)
Research & Academia
Doctoral degree in Computer Science
10,000+

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Xcel Energy
Data Science Intern CO, MN
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Xcel Energy
Added 1w ago
Data Science Intern CO, MN
Xcel Energy
Minneapolis, Minnesota
Customer Service
Customer Support
Hospitality & Guest Services
$22.1 - $27.9/hr
Hybrid

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Senior Data Science Engineer Jobs by City in Minnesota

Where Minnesota roles are concentrated, by current openings.

Minneapolis
6 jobs
Rochester
3 jobs
Saint Paul
2 jobs
Medina
1 job
Lakeville
1 job
Northfield
1 job
Bloomington
1 job
Eden Prairie
1 job

Senior Data Science Engineer Job Market in Minnesota

A snapshot from current Minnesota openings, updated as new roles post.

Who's Hiring

Mayo Clinic
Mayo Clinic3 open roles
University of Minnesota
University of Minnesota3 open roles
IDeaS
IDeaS1 open role

Top Industries Hiring

  • Education

What Minnesota Employers Look For

The qualifications that appear most often in senior data science engineer jobs across Minnesota.

  • Bachelor's or master's degree in computer science, statistics, or a related quantitative field
  • Five or more years of hands-on experience building and deploying machine learning models at scale
  • Proficiency in Python, SQL, and at least one major ML framework such as TensorFlow or PyTorch
  • Experience with cloud platforms including AWS, Azure, or Google Cloud for data pipeline and model deployment
  • Demonstrated ability to lead data science projects and mentor junior engineers through full delivery cycles
  • Strong communication skills to translate complex model outputs into business decisions for non-technical stakeholders

Senior Data Science Engineer Jobs in Minnesota: Frequently Asked Questions

How do you become a senior data science engineer in Minnesota?

Senior data science engineer roles in Minnesota do not require a state-issued license or registration. Employers in the Twin Cities, Rochester, and Bloomington typically look for a bachelor's or master's degree in computer science, statistics, or applied mathematics, combined with several years of progressive experience building production machine learning systems. Cloud certifications from AWS or Google Cloud and a strong portfolio of deployed models meaningfully strengthen candidacy with Minnesota's large healthcare and retail employers.

How much do senior data science engineers make in Minnesota?

Senior data science engineers in Minnesota earn a median of about $128,800 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $65,730 for the lowest 10% to over $179,640 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior data science engineers in Minnesota?

Employers hiring senior data science engineers in Minnesota right now include Mayo Clinic, University of Minnesota, and IDeaS, based on current listings on Migrate Mate as of October 2026. Minnesota's concentration of large healthcare systems, retail headquarters, and financial services firms creates consistent year-round demand for senior-level data science talent.

Which Minnesota cities have the most senior data science engineer jobs?

Minneapolis, Rochester, and Saint Paul have the most senior data science engineer openings in Minnesota. The Twin Cities metro drives the majority of postings because it is home to corporate headquarters for employers in retail, financial services, and healthcare technology, while Rochester's concentration around major medical institutions and Bloomington's insurance and professional services sector add a meaningful share of openings outside Minneapolis and Saint Paul.

Are there remote senior data science engineer jobs in Minnesota?

Yes, and more than most fields. About 88% of senior data science engineer openings tied to Minnesota are remote or hybrid as of October 2026, reflecting how thoroughly this role's core work, modeling, analysis, and pipeline development, happens on a laptop connected to cloud infrastructure. Roles requiring real-time collaboration with product or engineering teams are most likely to specify hybrid rather than fully remote arrangements.

How can I get hired as a senior data science engineer in Minnesota with little or no experience?

The most realistic path is moving into a data science engineer role from an adjacent position such as data analyst, data engineer, or software engineer, roles that large Minnesota employers in healthcare and retail hire frequently and that share significant technical overlap. Target associate data scientist or junior data engineer openings at companies such as UnitedHealth Group, Target, or 3M, which run structured early-career programs. Building a portfolio of end-to-end ML projects and earning a cloud platform certification gives candidates a concrete edge with Minnesota hiring managers.

Where can I find and apply to senior data science engineer jobs in Minnesota?

You can find and apply to senior data science engineer jobs in Minnesota on Migrate Mate, which lists current openings from employers across the state. Search the listings, find roles that match your experience and preferred location or work arrangement, and apply directly to the ones that fit.

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