Senior Software Engineering Jobs in Missouri
Senior Software Engineering jobs in Missouri are in strong demand, concentrated in financial technology, healthcare IT, defense contracting, and enterprise software, with openings at every level of seniority from senior individual contributor to staff and principal engineer. The largest hiring metros are Kansas City, St. Louis, and Columbia, where companies like Cerner (Oracle Health), Edward Jones, and Mastercard have deep engineering footprints. The most sought-after specialties in Missouri right now are cloud infrastructure, distributed systems, and full-stack product engineering. Scan the live roles below and apply to whichever ones fit.
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We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.
POSITION SUMMARY
CVS Health Digital is looking for hands-on, passionate people who want to join a high energy and growing team to make a difference in customers’ lives and who want to be on the forefront of digital innovation that aims to reinvent what a pharmacy and a health care company can be in the digital world. Currently, we are seeking Senior Manager – Software Development Engineering who will lead and manage a team of software engineers, providing hands-on technical direction, architecture guidance, and mentorship while establishing measurable engineering goals aligned with business outcomes. This Senior Engineer also will drive technical strategy and execution for software initiatives by defining system requirements, architecture, timelines, and deliverables.
Expectation For The Role:
- Own risk mitigation and production stability by proactively identifying system vulnerabilities, leading root cause analysis, and driving timely resolution of complex production issues to ensure high availability and minimal downtime
- Oversee the full software development lifecycle (SDLC), including requirements engineering, system design, development, testing, and deployment, ensuring adherence to modern engineering standards, secure coding practices, and scalable architecture principles
- Collaborate cross-functionally with Product, Data, Infrastructure, and business stakeholders to translate functional requirements into technical solutions, align priorities, and resolve dependencies while maintaining efficient delivery pipelines
- Continuously evaluate and adopt emerging technologies, frameworks, and engineering best practices, leading innovation through proof-of-concepts and informed technology selection to enhance system performance and developer productivity
- Build and develop high-performing engineering teams by hiring top talent, conducting technical performance evaluations, and fostering a culture of continuous improvement, technical excellence, and knowledge sharing
REQUIRED QUALIFICATIONS
- 7+ years of overall software engineering experience with at least 5+ years of experience of leading projects or managing directs
- 7+ years of experience using and/or managing projects using Java, Spring boot, Kafka to build/deploy, and maintain software applications using cloud platforms
- 3+ years of experience leading cross-functional teams without direct authority, including documented collaboration with engineering, architecture, security, and business stakeholders in a matrixed organization
- 3+ years of experience defining technology strategy and leading the adoption and operationalization of technologies such as AI/ML, cloud services, automation, and developer productivity tools in a large-scale enterprise environment with evidence of measurable impact (e.g., reduction in MTTR, cost savings, efficiency gains, or adoption KPIs)
- Strong expertise in cloud platforms, distributed systems, APIs, microservices, and modern software development practices
PREFERRED QUALIFICATIONS
- Experience with retail or health care industry with background in fulfillment, dispensing & delivery
- Experience with developing in AWS or GCP or Azure or similar public cloud environments (GCP preferred)
- Proven success driving technical strategy, engineering excellence, and organizational transformation
- Excellent communication, stakeholder management, and cross-functional collaboration skills
- Experience managing multiple teams and developing engineering leaders
- Ability to balance technical depth with business outcomes and strategic decision-making
- Ensured code quality and technical excellence through reviews, testing strategies, and debt management
- Owned system reliability and operational performance, including monitoring, incident management, and SLAs
EDUCATION
Bachelor’s degree or equivalent experience (High School Diploma and 4 years relevant experience)
BUSINESS OVERVIEW
Bring your heart to CVS Health Every one of us at CVS Health shares a single, clear purpose: Bringing our heart to every moment of your health. This purpose guides our commitment to deliver enhanced human-centric health care for a rapidly changing world. Anchored in our brand — with heart at its center — our purpose sends a personal message that how we deliver our services is just as important as what we deliver. Our Heart At Work Behaviors™ support this purpose. We want everyone who works at CVS Health to feel empowered by the role they play in transforming our culture and accelerating our ability to innovate and deliver solutions to make health care more personal, convenient and affordable. We strive to promote and sustain a culture of diversity, inclusion and belonging every day. CVS Health is an affirmative action employer, and is an equal opportunity employer, as are the physician-owned businesses for which CVS Health provides management services. We do not discriminate in recruiting, hiring, promotion, or any other personnel action based on race, ethnicity, color, national origin, sex/gender, sexual orientation, gender identity or expression, religion, age, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law. We proudly support and encourage people with military experience (active, veterans, reservists and National Guard) as well as military spouses to apply for CVS Health job opportunities.
Pay Range
The typical pay range for this role is:
$106,605.00 - $284,280.00
This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors. This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above. This position also includes an award target in the company’s equity award program.
Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.
Great benefits for great people
We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.
This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.
Additional details about available benefits are provided during the application process and on Benefits Moments.
We anticipate the application window for this opening will close on: 08/21/2026
Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.
See All 5 Senior Software Engineering Jobs in Missouri
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Where Missouri roles are concentrated, by current openings.
Senior Software Engineering Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Insurance
- Technology & Software
- Banking & Financial Services
What Missouri Employers Look For
The qualifications that appear most often in senior software engineering jobs across Missouri.
- Bachelor's degree in computer science, software engineering, or a closely related technical field
- Five or more years of professional software engineering experience with demonstrated ownership of complex systems
- Proficiency in at least one primary language such as Java, Python, Go, or C++ and related frameworks
- Experience designing and operating distributed systems or microservices in cloud environments like AWS or Azure
- Proven ability to lead technical design discussions, mentor engineers, and drive cross-team delivery
- Strong communication skills with a history of collaborating across product, data, and infrastructure teams
Senior Software Engineering Jobs in Missouri: Frequently Asked Questions
How do you become a senior software engineering in Missouri?
Reaching a senior software engineering role in Missouri typically requires a bachelor's degree in computer science or a related field, followed by several years of progressively complex engineering work. Missouri does not require a state-issued license for software engineers. Hiring managers in Kansas City and St. Louis generally expect candidates to demonstrate technical depth through a portfolio, system design experience, and evidence of leading or mentoring on past projects.
How much do senior software engineerings make in Missouri?
Senior software engineerings in Missouri earn a median of about $126,120 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $72,570 for the lowest 10% to over $169,340 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior software engineerings in Missouri?
Missouri senior software engineering roles are posted by The Cigna, Affirm, and CVS Health and others right now, based on current listings on Migrate Mate as of August 2026. Missouri's mix of large financial institutions, healthcare technology firms, and defense contractors means demand is spread across multiple stable industries rather than concentrated in a single sector.
Which Missouri cities have the most senior software engineering jobs?
St. Louis, St Louis, and Jefferson City have the most senior software engineering openings in Missouri. Kansas City and St. Louis account for most of the volume, driven by headquarters and large engineering centers for financial services, healthcare IT, and enterprise software companies, while Columbia benefits from university-affiliated research and growing startup activity anchored by the University of Missouri.
Are there remote senior software engineering jobs in Missouri?
Yes, and more than most fields. About 75% of senior software engineering openings tied to Missouri are remote or hybrid as of August 2026, reflecting how naturally portable this work is. The roles most likely to be fully remote are in product engineering, platform infrastructure, and SaaS development, while on-site presence is more common for defense-adjacent and regulated financial services positions.
How can I get hired as a senior software engineering in Missouri with little or no experience?
The most realistic entry path is building demonstrable project work through open-source contributions, personal repositories, or contract work and applying to associate or junior engineering roles at Missouri's large employers. Companies like Cerner (Oracle Health) and Edward Jones in Kansas City and St. Louis run structured new-graduate and rotational engineering programs that ladder toward senior roles. Lateral moves from QA engineering, technical support, or data analysis at the same employer are a proven route, and holding an AWS or Google Cloud associate certification strengthens a candidate's profile considerably.
Where can I find and apply to senior software engineering jobs in Missouri?
You can find and apply to senior software engineering jobs in Missouri on Migrate Mate, which lists current Missouri openings across Kansas City, St. Louis, Columbia, and beyond. Search the listings for roles that match your experience level and technical stack, then apply directly to the ones that fit.
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