Senior Software Engineering Jobs in Missouri
Senior Software Engineering jobs in Missouri are in strong demand, concentrated in financial technology, healthcare IT, defense contracting, and enterprise software, with openings at every level of seniority from senior individual contributor to staff and principal engineer. The largest hiring metros are Kansas City, St. Louis, and Columbia, where companies like Cerner (Oracle Health), Edward Jones, and Mastercard have deep engineering footprints. The most sought-after specialties in Missouri right now are cloud infrastructure, distributed systems, and full-stack product engineering. Scan the live roles below and apply to whichever ones fit.
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Our Purpose
Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential.
Title and Summary
Senior Vice President, Software Engineering Senior Vice President, Software Engineering – Decision Stream Engineering Co-FounderJob Description Summary
Who is Mastercard?
Mastercard is a global technology company in the payments industry. Our mission is to connect and power an inclusive, digital economy that benefits everyone, everywhere by making transactions safe, simple, smart, and accessible. Using secure data and networks, partnerships and passion, our innovations and solutions help individuals, financial institutions, governments, and businesses realize their greatest potential.
Our decency quotient, or DQ, drives our culture and everything we do inside and outside of our company. With connections across more than 210 countries and territories, we are building a sustainable world that unlocks priceless possibilities for all.
Overview
Decision Stream is Mastercard's next-generation, AI-native decisioning platform designed to deliver intelligent, real-time decisioning across payments, fraud, authentication, and adjacent risk domains. The platform is being built as a startup-style venture within Mastercard, combining the speed and innovation of a product startup with the scale, security, and reach of an enterprise platform.
We are seeking an Engineering Co-Founder to lead the engineering vision, architecture execution, talent strategy, and platform delivery for Decision Stream. This leader will partner closely with Product, Architecture, AI, Platform, and Foundry teams to build an industry-leading, cloud-native decisioning platform that redefines how decisions are made across Mastercard's ecosystem.
Engineering Leadership & Strategy
- Establish and execute the engineering vision for Decision Stream.
- Drive engineering priorities, technical investment decisions, and platform evolution.
- Create a high-performance culture built on ownership, innovation, accountability, and speed.
- Partner with executive leadership to define long-term technology strategy and roadmap.
Platform & Architecture
- Lead the development of a cloud-native, AI-native decisioning platform capable of operating at Mastercard scale.
- Drive architectural decisions across streaming, orchestration, rules execution, AI inference, observability, resiliency, and platform services.
- Ensure platform reliability, scalability, security, and operational excellence.
- Balance rapid experimentation with enterprise-grade engineering discipline.
Talent & Organization
- Build and scale world-class engineering teams across platform engineering, AI, distributed systems, and product development.
- Develop a lean operating model built around empowered cross-functional pods.
Product & Business Partnership
- Partner closely with the Product Co-Founder to align engineering investments with customer outcomes and business objectives.
- Work collaboratively across Product, Architecture, Foundry, Operations, and AI teams as one integrated leadership team.
- Drive a culture where engineering teams own outcomes
Execution & Delivery
- Lead the platform through MVP validation, commercialization readiness, and scaled adoption.
- Establish engineering metrics, governance, and operating rhythms.
- Drive rapid iteration cycles focused on learning, experimentation, and measurable outcomes.
- Remove organizational barriers and accelerate decision making across teams
- Create an environment where innovation and accountability coexist.
Qualifications
Leadership Expectations:
- Operate as an entrepreneur and builder.
- Demonstrate bias for action and comfort with ambiguity.
- Make decisions quickly using data and customer insights.
- Foster radical transparency and cross-functional collaboration.
- Inspire teams through vision, technical credibility, and execution excellence.
- Challenge conventional thinking while remaining focused on business outcomes.
Required
- Engineering leadership experience.
- Proven experience building and scaling large-scale distributed platforms.
- Deep expertise in cloud-native architecture, microservices, event-driven systems, and modern software engineering practices.
- Demonstrated success leading engineering organizations through transformation and growth.
- Experience delivering platforms requiring high availability, resiliency, and performance at significant scale.
- Strong executive communication and stakeholder management skills.
- Experience with AI/ML product platforms and intelligent decisioning systems.
- Expertise in streaming technologies such as Kafka, Flink, or similar event-processing architectures.
- Experience in payments, fraud, risk, authentication, or financial services technology.
- Background building startup ventures, innovation labs, or greenfield platforms.
- Record of leading globally distributed engineering organizations.
Corporate Security Responsibility
Every person working for, or on behalf of, Mastercard is responsible for information security. All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and therefore, it is expected that the successful candidate for this position must:
- Abide by Mastercard’s security policies and practices;
- Ensure the confidentiality and integrity of the information being accessed;
- Report any suspected information security violation or breach, and
- Complete all periodic mandatory security trainings in accordance with Mastercard’s guidelines
Total Base Pay Range 220,000.00 - 400,000.00 USD Annual Mastercard is a merit-based, inclusive, equal opportunity employer that considers applicants without regard to gender, gender identity, sexual orientation, race, ethnicity, disabled or veteran status, or any other characteristic protected by law. We hire the most qualified candidate for the role. In the US or Canada, if you require accommodations or assistance to complete the online application process or during the recruitment process, please contact reasonable_accommodation@mastercard.com and identify the type of accommodation or assistance you are requesting. Do not include any medical or health information in this email. The Reasonable Accommodations team will respond to your email promptly.
Corporate Security Responsibility
All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must:
Abide by Mastercard’s security policies and practices;
Ensure the confidentiality and integrity of the information being accessed;
Report any suspected information security violation or breach, and
Complete all periodic mandatory security trainings in accordance with Mastercard’s guidelines.
See All 7 Senior Software Engineering Jobs in Missouri
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Find JobsSenior Software Engineering Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Senior Software Engineering Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Insurance
- Technology & Software
What Missouri Employers Look For
The qualifications that appear most often in senior software engineering jobs across Missouri.
- Bachelor's degree in computer science, software engineering, or a closely related technical field
- Five or more years of professional software engineering experience with demonstrated ownership of complex systems
- Proficiency in at least one primary language such as Java, Python, Go, or C++ and related frameworks
- Experience designing and operating distributed systems or microservices in cloud environments like AWS or Azure
- Proven ability to lead technical design discussions, mentor engineers, and drive cross-team delivery
- Strong communication skills with a history of collaborating across product, data, and infrastructure teams
Senior Software Engineering Jobs in Missouri: Frequently Asked Questions
How do you become a senior software engineering in Missouri?
Reaching a senior software engineering role in Missouri typically requires a bachelor's degree in computer science or a related field, followed by several years of progressively complex engineering work. Missouri does not require a state-issued license for software engineers. Hiring managers in Kansas City and St. Louis generally expect candidates to demonstrate technical depth through a portfolio, system design experience, and evidence of leading or mentoring on past projects.
How much do senior software engineerings make in Missouri?
Senior software engineerings in Missouri earn a median of about $126,120 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $72,570 for the lowest 10% to over $169,340 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior software engineerings in Missouri?
Missouri senior software engineering roles are posted by The Cigna, RGA, and CVS Health and others right now, based on current listings on Migrate Mate as of September 2026. Missouri's mix of large financial institutions, healthcare technology firms, and defense contractors means demand is spread across multiple stable industries rather than concentrated in a single sector.
Which Missouri cities have the most senior software engineering jobs?
St. Louis, Missouri, and O'Fallon have the most senior software engineering openings in Missouri. Kansas City and St. Louis account for most of the volume, driven by headquarters and large engineering centers for financial services, healthcare IT, and enterprise software companies, while Columbia benefits from university-affiliated research and growing startup activity anchored by the University of Missouri.
Are there remote senior software engineering jobs in Missouri?
Yes, and more than most fields. About 50% of senior software engineering openings tied to Missouri are remote or hybrid as of September 2026, reflecting how naturally portable this work is. The roles most likely to be fully remote are in product engineering, platform infrastructure, and SaaS development, while on-site presence is more common for defense-adjacent and regulated financial services positions.
How can I get hired as a senior software engineering in Missouri with little or no experience?
The most realistic entry path is building demonstrable project work through open-source contributions, personal repositories, or contract work and applying to associate or junior engineering roles at Missouri's large employers. Companies like Cerner (Oracle Health) and Edward Jones in Kansas City and St. Louis run structured new-graduate and rotational engineering programs that ladder toward senior roles. Lateral moves from QA engineering, technical support, or data analysis at the same employer are a proven route, and holding an AWS or Google Cloud associate certification strengthens a candidate's profile considerably.
Where can I find and apply to senior software engineering jobs in Missouri?
You can find and apply to senior software engineering jobs in Missouri on Migrate Mate, which lists current Missouri openings across Kansas City, St. Louis, Columbia, and beyond. Search the listings for roles that match your experience level and technical stack, then apply directly to the ones that fit.
See All 7 Senior Software Engineering Jobs in Missouri
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