Biotech & Pharma Jobs in Massachusetts with E-3 Sponsorship
Massachusetts is one of the most active states for biotech and pharma E-3 sponsorship, anchored by the Kendall Square and Seaport District clusters in Cambridge and Boston. Major employers including Biogen, Moderna, Sanofi, and AstraZeneca regularly hire for roles that qualify as specialty occupations under E-3 requirements, making the state a strong destination for Australian life sciences professionals.
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Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
The Discovery Research mRNA-tLNP department is seeking a driven and collaborative Research Scientist to join our dynamic mRNA group. Our team partners with multidisciplinary groups across AbbVie to develop therapeutic solutions for diverse disease areas, including immunology, oncology, and neurology.
As a key member of the mRNA team, you will independently lead mRNA production efforts with the support of other team members, contribute to RNA platform innovation, and deliver high-quality mRNA drug substances for various therapeutic applications. You will collaborate closely with scientists from multiple functional areas and therapeutic teams, manage both internal and external partnerships, and actively contribute to the advancement of AbbVie’s mRNA capabilities.
Key Responsibilities:
- Develop and optimize mRNA purification processes using a variety of chromatography techniques on ÄKTA systems.
- Perform in vitro transcription (IVT), purification, and characterization of mRNA to produce therapeutic-grade materials for in vitro and in vivo studies.
- Establish high-throughput IVT and purification methods using liquid handling systems.
- Evaluate and integrate emerging technologies to enhance the RNA platform in support of cross-functional research initiatives.
- Communicate research progress through presentations and written reports to both scientific and non-scientific audiences, internally and externally.
- Supervise, mentor, and share expertise with colleagues across functions and project teams.
- Contribute to the preparation of publications, reports, and external presentations.
Qualifications
- BS with 7+ years, or MS with 5+ years, in biochemistry, molecular biology, or a related field, preferably with 1-3 years of direct mRNA therapy experience.
- Proficient in RNA in vitro transcription and chromatography-based RNA purification (ÄKTA systems experience preferred).
- Strong knowledge of other RNA formats (e.g., circular RNA, self-amplifying RNA) and their purification/characterization challenges.
- Familiar with implementation of liquid handling automation in laboratory workflows.
- Excellent documentation, organizational, and communication skills.
- Demonstrated ability to work independently and collaboratively in a fast-paced, team-oriented environment with strong problem-solving skills and a resilient mindset.
Additional Information
Key Competencies:
- Builds strong relationships with peers and cross functionally with partners to enable higher performance.
- Learns fast, grasps the "essence" and can change course quickly where indicated.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation and manages innovation to reality.
- Strong interpersonal and communication skills with proven ability to work within a team environment.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html

Company Description
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
The Discovery Research mRNA-tLNP department is seeking a driven and collaborative Research Scientist to join our dynamic mRNA group. Our team partners with multidisciplinary groups across AbbVie to develop therapeutic solutions for diverse disease areas, including immunology, oncology, and neurology.
As a key member of the mRNA team, you will independently lead mRNA production efforts with the support of other team members, contribute to RNA platform innovation, and deliver high-quality mRNA drug substances for various therapeutic applications. You will collaborate closely with scientists from multiple functional areas and therapeutic teams, manage both internal and external partnerships, and actively contribute to the advancement of AbbVie’s mRNA capabilities.
Key Responsibilities:
- Develop and optimize mRNA purification processes using a variety of chromatography techniques on ÄKTA systems.
- Perform in vitro transcription (IVT), purification, and characterization of mRNA to produce therapeutic-grade materials for in vitro and in vivo studies.
- Establish high-throughput IVT and purification methods using liquid handling systems.
- Evaluate and integrate emerging technologies to enhance the RNA platform in support of cross-functional research initiatives.
- Communicate research progress through presentations and written reports to both scientific and non-scientific audiences, internally and externally.
- Supervise, mentor, and share expertise with colleagues across functions and project teams.
- Contribute to the preparation of publications, reports, and external presentations.
Qualifications
- BS with 7+ years, or MS with 5+ years, in biochemistry, molecular biology, or a related field, preferably with 1-3 years of direct mRNA therapy experience.
- Proficient in RNA in vitro transcription and chromatography-based RNA purification (ÄKTA systems experience preferred).
- Strong knowledge of other RNA formats (e.g., circular RNA, self-amplifying RNA) and their purification/characterization challenges.
- Familiar with implementation of liquid handling automation in laboratory workflows.
- Excellent documentation, organizational, and communication skills.
- Demonstrated ability to work independently and collaboratively in a fast-paced, team-oriented environment with strong problem-solving skills and a resilient mindset.
Additional Information
Key Competencies:
- Builds strong relationships with peers and cross functionally with partners to enable higher performance.
- Learns fast, grasps the "essence" and can change course quickly where indicated.
- Raises the bar and is never satisfied with the status quo.
- Creates a learning environment, open to suggestions and experimentation for improvement.
- Embraces the ideas of others, nurtures innovation and manages innovation to reality.
- Strong interpersonal and communication skills with proven ability to work within a team environment.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
Job Roles in Biotech & Pharma in Massachusetts
See all 349+ Biotech & Pharma Massachusetts jobs
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Get Access To All JobsFrequently Asked Questions
Which biotech and pharma companies sponsor E-3 visas in Massachusetts?
Several large and mid-size employers in Massachusetts have established E-3 sponsorship track records, including Biogen, Moderna, Sanofi, AstraZeneca, Takeda, and Vertex Pharmaceuticals. Many clinical-stage biotechs headquartered in Cambridge and Boston also sponsor E-3 visas, though sponsorship willingness varies by role, headcount, and hiring cycle. Checking recent Labor Condition Application filings on the DOL OFLC disclosure database can confirm which employers have filed for E-3 workers.
Which cities in Massachusetts have the most biotech and pharma E-3 sponsorship jobs?
Cambridge and Boston together form the densest biotech and pharma hiring market in Massachusetts, particularly around Kendall Square, the Longwood Medical Area, and the Seaport District. Waltham and Lexington host a significant number of established pharma and contract research organizations. Worcester has a growing life sciences presence tied to its academic medical institutions. The vast majority of E-3 sponsorship opportunities in the state are concentrated in the Greater Boston corridor.
What types of biotech and pharma roles typically qualify for E-3 sponsorship?
E-3 sponsorship requires the role to qualify as a specialty occupation, meaning it must normally require at minimum a bachelor's degree in a specific field. In biotech and pharma, positions commonly meeting this standard include research scientists, bioinformaticians, clinical research associates, regulatory affairs specialists, biostatisticians, pharmacovigilance analysts, and process development engineers. Roles where any degree field is acceptable, or where experience substitutes freely for a degree requirement, are less likely to qualify.
How do I find biotech and pharma E-3 sponsorship jobs in Massachusetts?
Migrate Mate is built specifically for this search, letting you filter by visa type, state, and industry to surface biotech and pharma roles with E-3 sponsorship in Massachusetts. Because E-3 sponsorship is employer-driven, targeting companies with a demonstrated history of LCA filings in life sciences gives you better odds than applying broadly. Migrate Mate aggregates these opportunities so you are not manually sifting through listings that will not support your visa.
Are there any Massachusetts-specific or industry-specific considerations for E-3 sponsorship in biotech and pharma?
Massachusetts has a highly competitive life sciences hiring market, which generally works in favor of international candidates with specialized skills. However, smaller biotechs and early-stage startups may lack prior experience with E-3 sponsorship processes, so be prepared to provide employers with information about the visa category. The state's concentration of academic medical centers and research hospitals also creates a distinct set of employers, some of which hold cap-exempt H-1B status, though E-3 applications are handled through consular processing regardless.
What is the prevailing wage for E-3 biotech & pharma jobs in Massachusetts?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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