Applications Manager Jobs in Massachusetts

Applications Manager jobs in Massachusetts are in strong demand, with the role concentrated in healthcare IT, financial services, and enterprise software sectors and openings ranging from junior implementation specialists through senior platform owners. Boston, Cambridge, and Worcester anchor most of the hiring, with major employers such as Mass General Brigham, Liberty Mutual, and MathWorks maintaining consistent need for professionals who oversee business application portfolios. The most in-demand specialties are ERP administration, Salesforce ecosystem management, and healthcare application governance. Find a role that fits below and apply directly.

Find Applications Manager Jobs

Overview

Open roles15
Top employerScholar Rock
Top cityCambridge, MA
Cities hiring10
Work type40% On-site
Top industryManufacturing

Showing 4 of 15+ Applications Manager jobs

FLEXcon
Manager Applications Development Engineering
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FLEXcon
Added 2d ago
Manager Applications Development Engineering
FLEXcon
Spencer, Massachusetts
Business Operations
Program Management
Project & Program Management
Project Management
$101k - $168k/yr
Hybrid
Bachelor's degree
1,001-5,000

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Scholar Rock
Senior Manager, GxP Applications & Data
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Scholar Rock
Added 2d ago
Senior Manager, GxP Applications & Data
Scholar Rock
Cambridge, Massachusetts
Project & Program Management
Partnerships & Business Development
Compliance & Legal
Technical Product & Program Management
Quality Assurance & Testing (QA Testing)
Project Management
Technical Program Management
$195k/yr
On-Site
Bachelor's

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Scholar Rock
Senior Manager, Commercial Applications & Data
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Scholar Rock
Added 2d ago
Senior Manager, Commercial Applications & Data
Scholar Rock
Cambridge, Massachusetts
Project & Program Management
Technical Product & Program Management
Partnerships & Business Development
Compliance & Legal
Customer Success
Project Management
Technical Program Management
$195k/yr
On-Site
Bachelor's

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Beth Israel Lahey Health
Manager, EHR Applications-Patient Access
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Beth Israel Lahey Health
Added 1w ago
Manager, EHR Applications-Patient Access
Beth Israel Lahey Health
Charlestown, Massachusetts
Project Management
Software Engineering
Technical Product & Program Management
$139k - $175k/yr
Bachelor's degree in business

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See All 15 Applications Manager Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Applications Manager Jobs

Applications Manager Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Cambridge
4 jobs
Boston
3 jobs
Devens
1 job
Lowell
1 job
Holyoke
1 job
Spencer
1 job
Sudbury
1 job
Charlestown
1 job
Chestnut Hill
1 job

Applications Manager Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Scholar Rock
Scholar Rock2 open roles
P
PCS I1 open role
FLEXcon
FLEXcon1 open role

Top Industries Hiring

  • Manufacturing
  • Biotechnology & Pharmaceuticals
  • Education

What Massachusetts Employers Look For

The qualifications that appear most often in applications manager jobs across Massachusetts.

  • Bachelor's degree in computer science, information systems, or a related technical field
  • Proven experience managing enterprise applications such as ERP, CRM, or ITSM platforms
  • Strong project management skills with familiarity with Agile or ITIL frameworks
  • Ability to coordinate across IT, business, and vendor stakeholders on application lifecycle decisions
  • Experience with systems integration, configuration management, and application security practices
  • Relevant certifications such as PMP, Salesforce Administrator, or SAP credentials preferred

Applications Manager Jobs in Massachusetts: Frequently Asked Questions

How do you become a applications manager in Massachusetts?

Applications manager roles in Massachusetts do not require a state-issued license, so the path centers on education and experience. Most employers expect a bachelor's degree in information systems, computer science, or business technology. Candidates build toward the role by starting in application support, systems analysis, or IT administration, then advancing through increased ownership of enterprise platforms. Earning a platform-specific certification such as Salesforce Administrator or an ITIL credential is a recognized way to stand out in the Massachusetts market.

How much do applications managers make in Massachusetts?

Applications managers in Massachusetts earn a median of about $214,960 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $134,390 for the lowest 10% to over $308,250 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire applications managers in Massachusetts?

Employers hiring applications managers in Massachusetts right now include Scholar Rock, PCS I, and FLEXcon, based on current listings on Migrate Mate as of August 2026. Massachusetts's concentration of academic medical centers, insurance carriers, and technology firms means demand is spread across both mission-driven institutions and commercial enterprises throughout the state.

Which Massachusetts cities have the most applications manager jobs?

Cambridge, Boston, and Devens have the most applications manager openings in Massachusetts. Boston and Cambridge dominate because of the region's dense cluster of hospitals, biotech firms, financial institutions, and technology companies, while Worcester draws steady demand from large healthcare networks and regional universities that maintain substantial enterprise application environments.

Are there remote applications manager jobs in Massachusetts?

Yes, and they are more common than in many IT roles because applications management is largely a coordination and configuration discipline that does not require physical presence. About 60% of applications manager openings tied to Massachusetts are remote or hybrid as of August 2026, reflecting the desk-based nature of the work. Responsibilities such as vendor management, release planning, and user support are particularly well suited to remote or hybrid arrangements.

How can I get hired as a applications manager in Massachusetts with little or no experience?

The most realistic entry path is a help desk or application support role at a large Massachusetts employer such as a hospital network, university, or insurance company, where you gain direct exposure to enterprise systems. Mass General Brigham, UMass Memorial Health, and Liberty Mutual all bring in IT associates and junior analysts who grow into application ownership over time. Building a portfolio around a specific platform, earning a free Salesforce or ServiceNow credential, and targeting IT coordinator postings at these institutions gives candidates without management experience a concrete foot in the door.

Where can I find and apply to applications manager jobs in Massachusetts?

You can find and apply to applications manager jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings from employers actively hiring right now. Find roles that fit your experience and apply directly without needing to go through a separate sign-up process.

See All 15 Applications Manager Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Applications Manager Jobs