Chief Operating Officer Jobs in Massachusetts

Chief Operating Officer jobs in Massachusetts are in strong demand, with openings concentrated in life sciences, financial services, technology, and healthcare across a market that runs from early-career operations roles through C-suite executive appointments. Boston, Cambridge, and Worcester anchor most of the hiring, with well-established employers such as Mass General Brigham, State Street, and Biogen consistently seeking chief operating officers across their business units and portfolio companies. The most sought-after specialties in Massachusetts center on life sciences operations, fintech scaling, and healthcare system management. Find a role that fits below and apply directly.

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Overview

Open roles183+
Top employerBeth Israel Lahey Health
Top cityBoston, MA
Cities hiring58
Work type55% Hybrid
Top industryBiotechnology

Showing 5 of 183+ Chief Operating Officer jobs

Baystate Health
Director Patient Care Services – Medical Surgical Nursing & Clinical Operations
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Baystate Health
Added 1d ago
Director Patient Care Services – Medical Surgical Nursing & Clinical Operations
Baystate Health
Springfield, Massachusetts
Business Operations
Corporate Development & M&A
Executive Leadership & C-Suite
$158k - $215k/yr
Managed Registered Nurses (RNs)
1,001-5,000

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Massachusetts Port Authority
Assistant Director Aviation Security Operations
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Massachusetts Port Authority
Added 1d ago
Assistant Director Aviation Security Operations
Massachusetts Port Authority
Boston, Massachusetts
Corporate Training
Corporate Training & Learning Development
Teaching & Instruction
$145k - $166k/yr
Bachelor's degree
1,001-5,000

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LCB Senior Living, LLC
Restaurant Operations Director The Residence at Five Corners
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LCB Senior Living, LLC
Added 1d ago
Restaurant Operations Director The Residence at Five Corners
LCB Senior Living, LLC
Easton, Massachusetts
Project Management
Solutions Engineering & Architecture
Technical Program Management
$70k - $80k/yr
1,001-5,000

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Moderna
Associate Director, Business Operations, Quality Control
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Moderna
Added 1d ago
Associate Director, Business Operations, Quality Control
Moderna
Norwood, Massachusetts
Administrative & Office Support
Customer Service
Customer Support
$143k - $257k/yr
Bachelor's degree in industrial engineering
1,001-5,000

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Rhythm Pharmaceuticals
Director, Field Operations & Effectiveness
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Rhythm Pharmaceuticals
Added 1d ago
Director, Field Operations & Effectiveness
Rhythm Pharmaceuticals
Boston, Massachusetts
Business Operations
Compensation & Benefits
Human Resources (HR) — Generalist
$182k - $275k/yr
Bachelor's degree
51-200

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See All 183+ Chief Operating Officer Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

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Chief Operating Officer Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Boston
64 jobs
Waltham
10 jobs
Somerville
4 jobs
Marlborough
4 jobs
Andover
3 jobs
Norwood
3 jobs
Braintree
3 jobs
Wellesley
3 jobs

Chief Operating Officer Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Beth Israel Lahey Health
Beth Israel Lahey Health6 open roles
Viridian Therapeutics
Viridian Therapeutics5 open roles
Takeda Pharmaceuticals
Takeda Pharmaceuticals5 open roles

Top Industries Hiring

  • Biotechnology & Pharmaceuticals
  • Education
  • Science & Research
  • Staffing & Recruiting
  • Construction & Real Estate

What Massachusetts Employers Look For

The qualifications that appear most often in chief operating officer jobs across Massachusetts.

  • Bachelor's degree in business administration, operations management, or a related field required
  • Ten or more years of progressive leadership experience in operations or general management
  • Proven experience leading cross-functional teams across multiple business units or divisions
  • Deep familiarity with life sciences, financial services, or healthcare operations in Massachusetts
  • Experience driving P&L accountability and translating strategy into measurable operational outcomes
  • Strong background in change management, process improvement, and scaling high-growth organizations

Chief Operating Officer Jobs in Massachusetts: Frequently Asked Questions

How do you become a chief operating officer in Massachusetts?

Becoming a chief operating officer in Massachusetts typically requires a bachelor's degree in business, engineering, or a related discipline, with most candidates also holding an MBA from institutions such as Harvard Business School, MIT Sloan, or Babson College. There is no state-issued license for this role. Employers here prioritize a progression through director and VP-level operations roles within Massachusetts industries like life sciences, healthcare systems, or financial services before making C-suite appointments.

Which companies hire chief operating officers in Massachusetts?

Employers hiring chief operating officers in Massachusetts right now include Beth Israel Lahey Health, Viridian Therapeutics, and Takeda Pharmaceuticals, based on current listings on Migrate Mate as of October 2026. Massachusetts's dense concentration of biotech, hospital networks, and asset management firms means openings appear regularly across both large anchor institutions and fast-growing venture-backed companies in the Greater Boston corridor.

Which Massachusetts cities have the most chief operating officer jobs?

Boston, Cambridge, and Waltham have the most chief operating officer openings in Massachusetts. Boston dominates because of its headquarters density across financial services, healthcare, and technology, while Cambridge draws heavily from its biotech and research institution cluster, and Worcester reflects growing demand from regional health systems and manufacturing operations expanding outside the immediate Boston metro.

Are there remote chief operating officer jobs in Massachusetts?

Yes, but they're rare. Chief operating officers are typically expected on-site to lead teams, manage facilities, and respond to operational issues in real time. About 76% of chief operating officer openings tied to Massachusetts are remote or hybrid as of October 2026, and those tend to be at technology or platform companies where core operations can be managed digitally rather than in person.

How can I get hired as a chief operating officer in Massachusetts with little or no experience?

The most realistic entry path is building operations experience through director-level roles in program management, supply chain, or clinical operations at Massachusetts employers such as large hospital networks, contract research organizations, or fintech firms. From there, lateral moves into VP of Operations or General Manager positions create the stepping stones. An MBA from a Massachusetts institution strengthens candidacy considerably, and certifications in Lean or Six Sigma are recognized differentiators in manufacturing and life sciences hiring here.

Where can I find and apply to chief operating officer jobs in Massachusetts?

You can find and apply to chief operating officer jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings updated regularly. Search the available roles, find the ones that match your experience and target industry, and apply directly to each position without creating a profile or going through an intermediary.

See All 183+ Chief Operating Officer Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Chief Operating Officer Jobs