Clinical Project Manager Jobs in Delaware
Clinical Project Manager jobs in Delaware are concentrated in the pharmaceutical, biotech, and contract research organization sectors, with demand from entry-level coordinators through senior PMs overseeing late-phase trials. The Wilmington metro is the primary hiring hub, followed by Newark and the Route 202 corridor, where established employers like AstraZeneca, Incyte, and ChristianaCare maintain clinical operations teams. Regulatory affairs integration, oncology trial management, and CRO partnership coordination are the most in-demand specialties across the state. See the openings below and apply to the ones that match your experience.
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Quantitative Analytics Lead– Model Risk Management
Location: Wilmington, DE (Hybrid)
OneMain is seeking a Quantitative Analytics Lead, Model Risk Management (MRM) to help lead and strengthen the firm’s Model Risk Management program in alignment with regulatory guidance, including SR 11‑7 and OCC supervisory expectations. This role supports a diverse consumer credit portfolio, including Personal Loans, Credit Cards, Automotive, and Point‑of‑Sale lending.
The position offers a unique opportunity to apply advanced analytics and machine learning expertise while exercising independent challenge across the full model lifecycle. The role also plays a key part in regulatory readiness, audit engagement, and the continued evolution of OneMain’s Fair Lending analytical governance framework.
Responsibilities
- Provide hands‑on model governance oversight across the full model lifecycle, including development, implementation, validation, use, and ongoing monitoring of machine learning models supporting marketing, origination, servicing, and loss mitigation.
- Perform independent and effective challenge of models, assessing conceptual soundness, data integrity, methodology, assumptions, and limitations. Evaluate key development decisions, including target construction, training versus validation strategies, sampling approaches, performance windows, hyper‑parameter tuning, model performance metrics, variable selection, and swap‑set analyses.
- Provide robust challenge and governance oversight of CECL and loss forecasting models, serving as a central point of contact for internal audit, external audit, and regulatory examinations. Prepare clear, well‑supported model governance and validation documentation in support of model approvals and ongoing use.
- Conduct periodic model validations and assess whether validation activities performed by internal teams or third parties meet Model Risk Management policy requirements, including outcomes analysis, benchmarking, and sensitivity testing, as appropriate.
- Apply analytics, business rules, and other risk tools to monitor model performance and behavior, identify emerging risks or anomalies, and recommend remediation or model enhancements when warranted.
- Contribute to the ongoing modernization of the MRM function by leveraging advanced analytics and AI‑enabled tools to improve governance efficiency, documentation quality, and knowledge management.
- Participate in broader artificial intelligence and advanced analytics initiatives in partnership with the data science & technology organization, ensuring appropriate governance and risk controls are embedded from inception.
- Support OneMain’s Fair Lending Analytics Program by developing fair lending models and conducting statistically rigorous analyses to assess potential disparate impact and compliance risk.
- Apply regression, classification, and related statistical techniques to perform deep‑dive analyses, clearly articulating both statistical and practical significance to inform risk decisions and regulatory communications.
Qualifications
- Master’s degree in a quantitative discipline (Statistics, Mathematics, Data Science, or related field) required; PhD preferred.
- 3+ years of experience in statistics, data science, decision science, or a related quantitative field.
- 3+ years of experience building, reviewing, or validating machine learning models within the consumer finance industry.
- Strong understanding of consumer lending products, credit risk practices, and regulatory expectations related to model risk management.
- Hands‑on experience with machine learning techniques, particularly tree‑based models such as XGBoost, and strong analytical “deep‑dive” capabilities.
- Exposure to modern AI concepts, including Generative AI, Large Language Models (LLMs), and Retrieval‑Augmented Generation (RAG) systems, with an appreciation for associated governance and risk considerations.
- Proven ability to lead and manage complex, ambiguous projects and provide structured, defensible analytical judgment.
- Strong written and verbal communication skills, with the ability to explain complex technical concepts to non‑technical stakeholders, auditors, and regulators.
- Demonstrated intellectual curiosity, strong idea generation, and an interest in research, innovation, and continuous improvement.
- Proficiency in Python and SQL; experience with AWS and SageMaker is a strong plus.
Who We Are
OneMain Financial (NYSE: OMF) is the leader in offering nonprime customers responsible access to credit and is dedicated to improving the financial well-being of hardworking Americans. Since 1912, we’ve looked beyond credit scores to help people get the money they need today and reach their goals for tomorrow. Our growing suite of personal loans, credit cards and other products help people borrow better and work toward a brighter future.
Driven collaborators and innovators, our team thrives on transformative digital thinking, customer-first energy and flexible work arrangements that grow lives, careers and our company. At every level, we’re committed to an inclusive culture, career development and impacting the communities where we live and work. Getting people to a better place has made us a better company for over a century. There’s never been a better time to shine with OneMain.
Because team members at their best means OneMain at our best, we provide opportunities and benefits that make their health and careers a priority. That’s why we’ve packed our comprehensive benefits package for full- and some part-timers with:
Health and wellbeing options including medical, prescription, dental, vision, hearing, accident, hospital indemnity, and life insurances
Up to 4% matching 401(k)
Employee Stock Purchase Plan (10% share discount)
Tuition reimbursement
Paid time off (15 days’ vacation per year, plus 2 personal days, prorated based on start date)
Paid sick leave as determined by state or local ordinance, prorated based on start date
Paid holidays (11 days per year, based on start date)
Paid volunteer time (3 days per year, prorated based on start date)
OneMain Holdings, Inc. is an Equal Employment Opportunity (EEO) employer. Qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship status, color, creed, culture, disability, ethnicity, gender, gender identity or expression, genetic information or history, marital status, military status, national origin, nationality, pregnancy, race, religion, sex, sexual orientation, socioeconomic status, transgender or on any other basis protected by law.
See All 223+ Clinical Project Manager Jobs in Delaware
Find roles in Delaware that match your experience and apply in just a few clicks.
Find Clinical Project Manager JobsClinical Project Manager Jobs by City in Delaware
Where Delaware roles are concentrated, by current openings.
Clinical Project Manager Job Market in Delaware
A snapshot from current Delaware openings, updated as new roles post.
Who's Hiring
- JPMorganChase47

- LifeStance Health23

- Citi12

- Sargent & Lundy12

- ChristianaCare11

Top Industries Hiring
- Healthcare & Medical Services60
- Banking & Financial Services44
- Investment & Asset Management38
- Fintech26
- Technology & Software16
What Delaware Employers Look For
The qualifications that appear most often in clinical project manager jobs across Delaware.
- PMP or equivalent project management certification preferred by most Delaware clinical employers
- Bachelor's degree in life sciences, public health, or a related field required
- Minimum two to five years of clinical trial or drug development project management experience
- Familiarity with ICH-GCP guidelines and FDA regulatory submission processes
- Proficiency in clinical trial management systems such as Veeva Vault or Medidata Rave
- Strong cross-functional communication skills for coordinating with CROs, sites, and sponsors
Clinical Project Manager Jobs in Delaware: Frequently Asked Questions
How do you become a clinical project manager in Delaware?
The most direct path is a bachelor's degree in a life sciences or health-related field followed by experience in clinical research coordination or trial operations. Delaware does not require a state-issued license specific to clinical project management, but employers consistently expect PMP certification or a Certified Clinical Research Professional credential from the Association of Clinical Research Professionals. Building experience at a CRO, academic medical center, or pharmaceutical company in the Wilmington or Newark area positions candidates well.
How much do clinical project managers make in Delaware?
Clinical project managers in Delaware earn a median of about $122,190 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $74,770 for the lowest 10% to over $166,660 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinical project managers in Delaware?
Companies currently hiring clinical project managers in Delaware include JPMorganChase, LifeStance Health, and Citi, per current listings on Migrate Mate as of July 2026. Delaware's concentration of pharmaceutical headquarters and contract research organizations along the Wilmington corridor makes it one of the more active states for clinical PM hiring on the East Coast.
Which Delaware cities have the most clinical project manager jobs?
Wilmington, Newark, and New Castle lead Delaware for clinical project manager openings. Wilmington drives the majority of demand as the home base for major pharmaceutical and biotech employers, while Newark and smaller Route 202 corridor communities fill out the list through CRO offices, ChristianaCare's health system operations, and University of Delaware-affiliated research partnerships.
Are there remote clinical project manager jobs in Delaware?
Yes, and more than many clinical roles allow. About 57% of clinical project manager openings tied to Delaware are remote or hybrid as of July 2026, reflecting the desk-based and coordination-heavy nature of the PM function. Study startup, vendor oversight, and regulatory document management tasks are the most frequently performed remotely, while site initiation visits and sponsor meetings typically still require in-person presence.
How can I get hired as a clinical project manager in Delaware with little or no experience?
Starting as a clinical research coordinator or clinical trial associate at a Delaware CRO or hospital system is the most realistic entry point. ChristianaCare and Nemours Children's Health both run clinical research programs that bring in coordinators without prior PM experience. Earning a Certified Clinical Research Associate credential and volunteering on institutional review board committees at the University of Delaware can also distinguish an early-career candidate. Transitioning from adjacent roles such as regulatory affairs specialist or data manager is a common lateral move that leading Delaware employers recognize.
Where can I find and apply to clinical project manager jobs in Delaware?
You can find and apply to clinical project manager jobs in Delaware on Migrate Mate, which lists current openings across the state. Search the roles that fit your background and experience level, then apply directly to the ones that match. The listings are updated regularly, so checking back frequently gives you the best shot at catching new postings early.
See All 223+ Clinical Project Manager Jobs in Delaware
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