Clinical Registered Nurse Jobs in Mississippi
Clinical Registered Nurse jobs in Mississippi are concentrated in Jackson, Gulfport, and Hattiesburg, where major health systems like Merit Health, Singing River Health System, and Forrest Health maintain consistent hiring pipelines for clinical roles. Demand is especially strong in critical care, emergency nursing, and med-surg, with openings at every level from new graduate to experienced charge nurse. Mississippi's growing rural health infrastructure also drives steady placement across community hospitals and federally qualified health centers statewide. See the openings below and apply to the ones that match your experience.
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Grow Your Career with HealthTrust & Community Health System (CHS)
Looking to expand your nursing career in a new location? HealthTrust Workforce Solutions has partnered with CHS to provide travel nurse opportunities through a nationwide network of caring, compassionate, and inclusive facilities focused on making our communities healthier.
As an integrated network, CHS facilities have the ability and resources to develop opportunities for professional growth and advancement to accomplish your career goals, backed by pride in personalized patient care that supports a culture of safety for both employees and patients.
Combined with HWS’s commitment to the improvement of human life and experience as an industry leader for over 25 years, our CHS partnership gives you the opportunity to be at the heart of your community and care for your neighbors.
This community hospital is seeking a highly skilled nurse to join their team for an 8, 10, or 13 week assignment based on the facility need.
What You’ll Do:
- Perform plan of care intervention, including medication administration, specimen collection, clinical treatments, and other medical care, documenting care given
- Monitor, records, and communicate patient condition as appropriate to care team, physician, patient, and family
- Collaborate as needed across disciplines to coordinate patient care, including patient transfer, discharge, referral, and spiritual/psychosocial support needs
- Evaluate learning needs of patient and/or family and provide patient/family education appropriate to age, culture, condition, and circumstances
- Work as an advocate for the physical and emotional well-being of the patient
What We Require from You:
- Minimum of one (1) year acute care experience in a hospital setting
- Current state nursing license
- Appropriate certifications as required for specific position
- Degree from an accredited school
- Demonstrate code of conduct and compliance policies
- Ability to communicate clearly with the ability to read, write, speak, and understand English
Why You Will Love Working for HealthTrust:
- Weekly direct deposit pay options
- Guaranteed hours
- 401K with company match
- Ability to earn up to $750 for each referral
- Free private furnished housing or tax-free subsidy
- Career development for your lifestyle and location preference through a wide network of facilities
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Location:
ID:
Location: Merit Health Natchez - 54 Seargent Pretiss Drive Natchez, MS 39120
ID: 1042807
Job Board: EV
IND_2
ReqID: 1042807
Category: Travel
Job Type: Full Time
Position Type: Travel
HWS Exclusives: Yes
\#noapply
Min Pay Rate: $52.56
Max Pay Rate: $56.21
See All 31 Clinical Registered Nurse Jobs in Mississippi
Find roles in Mississippi that match your experience and apply in just a few clicks.
Find JobsClinical Registered Nurse Jobs by City in Mississippi
Where Mississippi roles are concentrated, by current openings.
Clinical Registered Nurse Job Market in Mississippi
A snapshot from current Mississippi openings, updated as new roles post.
Who's Hiring
- Baptist Memorial Health Care12

- University of Mississippi Medical Center8

- HealthTrust Workforce Solutions5

- VitalCaring2

- Memorial Hospital at Gulfport2

Top Industries Hiring
- Healthcare & Medical Services
What Mississippi Employers Look For
The qualifications that appear most often in clinical registered nurse jobs across Mississippi.
- Active registered nurse license issued or recognized by the Mississippi Board of Nursing
- Associate or bachelor's degree in nursing from an accredited program
- Current BLS certification required, ACLS preferred for critical care and ED roles
- Minimum one to two years of clinical bedside experience in an acute care setting
- Proficiency with electronic health record systems such as Epic or Meditech
- Strong assessment, critical thinking, and patient communication skills
Clinical Registered Nurse Jobs in Mississippi: Frequently Asked Questions
How do you become a clinical registered nurse in Mississippi?
You must earn a nursing degree from an accredited program, either an Associate Degree in Nursing or a Bachelor of Science in Nursing, then pass the NCLEX-RN exam to qualify for licensure. The Mississippi Board of Nursing issues RN licenses and oversees initial applications, endorsements from other states, and renewals. Mississippi also participates in the Nurse Licensure Compact, meaning nurses already licensed in another compact state can practice in Mississippi without obtaining a separate license.
How much do clinical registered nurses make in Mississippi?
Clinical registered nurses in Mississippi earn a median of about $77,090 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,610 for the lowest 10% to over $100,350 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinical registered nurses in Mississippi?
Employers hiring clinical registered nurses in Mississippi right now include Baptist Memorial Health Care, University of Mississippi Medical Center, and HealthTrust Workforce Solutions, based on current listings on Migrate Mate as of October 2026. Mississippi's largest hiring volume comes from regional health systems, critical access hospitals, and long-term acute care facilities spread across the Jackson metro and Gulf Coast corridor.
Which Mississippi cities have the most clinical registered nurse jobs?
The Mississippi cities with the most clinical registered nurse openings are Jackson, Southaven, and Vicksburg. Jackson leads as the state capital and home to the University of Mississippi Medical Center and several competing health systems, while Gulfport and Hattiesburg anchor strong hospital markets on the Gulf Coast and in the Pine Belt, drawing both regional patients and travel nurses who convert to permanent positions.
How can I get hired as a clinical registered nurse in Mississippi with little or no experience?
The most realistic entry path is a new graduate residency program, and Mississippi's larger systems actively run them. The University of Mississippi Medical Center and Merit Health facilities in the Jackson metro offer structured nurse residencies that accept NCLEX-new-passes and provide supervised clinical rotations before independent assignment. Applying to med-surg or step-down units first is a proven lateral move since those floors train nurses broadly and frequently feed into specialty positions. Holding an active Mississippi RN license and a completed ACLS course gives candidates a concrete edge over other applicants with no floor experience.
Where can I find and apply to clinical registered nurse jobs in Mississippi?
You can find and apply to clinical registered nurse jobs in Mississippi on Migrate Mate, which lists current openings tied to Mississippi employers. Search the listings to find roles that match your specialty and experience level, then apply directly to the ones that fit.
See All 31 Clinical Registered Nurse Jobs in Mississippi
Find roles in Mississippi that match your experience and apply in just a few clicks.
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