Clinical Registered Nurse Jobs in Mississippi

Clinical Registered Nurse jobs in Mississippi are concentrated in Jackson, Gulfport, and Hattiesburg, where major health systems like Merit Health, Singing River Health System, and Forrest Health maintain consistent hiring pipelines for clinical roles. Demand is especially strong in critical care, emergency nursing, and med-surg, with openings at every level from new graduate to experienced charge nurse. Mississippi's growing rural health infrastructure also drives steady placement across community hospitals and federally qualified health centers statewide. See the openings below and apply to the ones that match your experience.

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Overview

Open roles32
Top employerHealthTrust Workforce Solutions
Top cityJackson, MS
Cities hiring16
Work type100% On-site
Top industryHealthcare

Showing 5 of 32+ Clinical Registered Nurse jobs

Fresenius Medical Care
Dialysis Clinical Manager Registered Nurse - RN
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Fresenius Medical Care
Added 1d ago
Dialysis Clinical Manager Registered Nurse - RN
Fresenius Medical Care
Aberdeen, Mississippi
Customer Service
Customer Support
Hospitality & Guest Services
Managed Registered Nurses (RNs)
10,000+

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HealthTrust Workforce Solutions
Clinical | Travel:Registered Nurse (RN) / Medical Surgical - Contract - Nights
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HealthTrust Workforce Solutions
Added 5d ago
Clinical | Travel:Registered Nurse (RN) / Medical Surgical - Contract - Nights
HealthTrust Workforce Solutions
Vicksburg, Mississippi
Business Development
Growth Marketing
Marketing
$50.4 - $53.9/hr
1,001-5,000

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HealthTrust Workforce Solutions
Clinical | Travel:Registered Nurse (RN) / Medical Surgical - Contract - Nights
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HealthTrust Workforce Solutions
Added 5d ago
Clinical | Travel:Registered Nurse (RN) / Medical Surgical - Contract - Nights
HealthTrust Workforce Solutions
Flowood, Mississippi
Healthcare Administration
Nursing
Patient Services & Wellbeing
$50.4 - $53.9/hr
1,001-5,000

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Diversicare Healthcare Services
RN Clinical Educator
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Diversicare Healthcare Services
Added 5d ago
RN Clinical Educator
Diversicare Healthcare Services
Amory, Mississippi
Healthcare Administration
Patient Services & Wellbeing
Public Health
5,001-10,000

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University of Mississippi Medical Center
RN Clinical Research - Infectious Disease - FT
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University of Mississippi Medical Center
Added 6d ago
RN Clinical Research - Infectious Disease - FT
University of Mississippi Medical Center
Jackson, Mississippi
Biotech & Life Sciences
Clinical Support
Laboratory Science
5,001-10,000

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See All 32 Clinical Registered Nurse Jobs in Mississippi

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Clinical Registered Nurse Jobs by City in Mississippi

Where Mississippi roles are concentrated, by current openings.

Jackson
5 jobs
Natchez
5 jobs
Southaven
5 jobs
Tupelo
2 jobs
Clinton
2 jobs
Flowood
2 jobs
Vicksburg
2 jobs
Amory
1 job
Biloxi
1 job

Clinical Registered Nurse Job Market in Mississippi

A snapshot from current Mississippi openings, updated as new roles post.

Who's Hiring

HealthTrust Workforce Solutions
HealthTrust Workforce Solutions9 open roles
Baptist Memorial Health Care
Baptist Memorial Health Care8 open roles
Fresenius Medical Care
Fresenius Medical Care4 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What Mississippi Employers Look For

The qualifications that appear most often in clinical registered nurse jobs across Mississippi.

  • Active registered nurse license issued or recognized by the Mississippi Board of Nursing
  • Associate or bachelor's degree in nursing from an accredited program
  • Current BLS certification required, ACLS preferred for critical care and ED roles
  • Minimum one to two years of clinical bedside experience in an acute care setting
  • Proficiency with electronic health record systems such as Epic or Meditech
  • Strong assessment, critical thinking, and patient communication skills

Clinical Registered Nurse Jobs in Mississippi: Frequently Asked Questions

How do you become a clinical registered nurse in Mississippi?

You must earn a nursing degree from an accredited program, either an Associate Degree in Nursing or a Bachelor of Science in Nursing, then pass the NCLEX-RN exam to qualify for licensure. The Mississippi Board of Nursing issues RN licenses and oversees initial applications, endorsements from other states, and renewals. Mississippi also participates in the Nurse Licensure Compact, meaning nurses already licensed in another compact state can practice in Mississippi without obtaining a separate license.

How much do clinical registered nurses make in Mississippi?

Clinical registered nurses in Mississippi earn a median of about $77,090 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,610 for the lowest 10% to over $100,350 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical registered nurses in Mississippi?

Employers hiring clinical registered nurses in Mississippi right now include HealthTrust Workforce Solutions, Baptist Memorial Health Care, and Fresenius Medical Care, based on current listings on Migrate Mate as of August 2026. Mississippi's largest hiring volume comes from regional health systems, critical access hospitals, and long-term acute care facilities spread across the Jackson metro and Gulf Coast corridor.

Which Mississippi cities have the most clinical registered nurse jobs?

The Mississippi cities with the most clinical registered nurse openings are Jackson, Natchez, and Southaven. Jackson leads as the state capital and home to the University of Mississippi Medical Center and several competing health systems, while Gulfport and Hattiesburg anchor strong hospital markets on the Gulf Coast and in the Pine Belt, drawing both regional patients and travel nurses who convert to permanent positions.

Are there remote clinical registered nurse jobs in Mississippi?

Yes, but they're rare. Clinical registered nursing is fundamentally a hands-on, bedside role, so most positions require in-person presence. About 0% of clinical registered nurse openings tied to Mississippi are remote or hybrid as of August 2026, and those tend to be telehealth triage, utilization review, or care management roles where direct patient contact is handled by phone or video rather than at the bedside.

How can I get hired as a clinical registered nurse in Mississippi with little or no experience?

The most realistic entry path is a new graduate residency program, and Mississippi's larger systems actively run them. The University of Mississippi Medical Center and Merit Health facilities in the Jackson metro offer structured nurse residencies that accept NCLEX-new-passes and provide supervised clinical rotations before independent assignment. Applying to med-surg or step-down units first is a proven lateral move since those floors train nurses broadly and frequently feed into specialty positions. Holding an active Mississippi RN license and a completed ACLS course gives candidates a concrete edge over other applicants with no floor experience.

Where can I find and apply to clinical registered nurse jobs in Mississippi?

You can find and apply to clinical registered nurse jobs in Mississippi on Migrate Mate, which lists current openings tied to Mississippi employers. Search the listings to find roles that match your specialty and experience level, then apply directly to the ones that fit.

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