Clinical Registered Nurse Jobs in Oklahoma

Clinical Registered Nurse jobs in Oklahoma are concentrated in Oklahoma City, Tulsa, and Lawton, where demand is strong from new graduate level through experienced charge and specialty nurse. Major systems with consistent hiring include INTEGRIS Health, Ascension St. John, and OU Health, which operate large acute care and specialty facilities across the state. The most in-demand specialties in Oklahoma right now are critical care, med-surg, and emergency nursing. See the openings below and apply to the ones that match your experience.

Find Jobs

Overview

Open roles37
Top employerEnhabit Home Health & Hospice
Top cityOklahoma City, OK
Cities hiring13
Work type80% On-site
Top industryHealthcare

Showing 5 of 37+ Clinical Registered Nurse jobs

CommunityCare
Quality Improvement - Clinical Quality Program RN (STARS) 195-2023
We won't show you this job again
CommunityCare
New 10h ago
Quality Improvement - Clinical Quality Program RN (STARS) 195-2023
CommunityCare
Tulsa, Oklahoma
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Managed care

Have you applied for this role?

AMG, Integrated Healthcare Management
Clinical Supervisor (RN) Ft Nights
We won't show you this job again
AMG, Integrated Healthcare Management
Added 5d ago
Clinical Supervisor (RN) Ft Nights
AMG, Integrated Healthcare Management
Oklahoma City, Oklahoma
Healthcare Administration
Human Resources
Nursing
BLS Certification
51-200

Have you applied for this role?

HealthTrust Workforce Solutions
Clinical | Travel:(RN) / Operating Room (OR) - Contract - Days
We won't show you this job again
HealthTrust Workforce Solutions
Added 6d ago
Clinical | Travel:(RN) / Operating Room (OR) - Contract - Days
HealthTrust Workforce Solutions
Durant, Oklahoma
Executive Leadership & C-Suite
Program Management
Project Management
$52.92 - $56.6/hr
1,001-5,000

Have you applied for this role?

Option Care Health
Clinical Care Transition Specialist / Registered Nurse - Oklahoma City
We won't show you this job again
Option Care Health
Added 6d ago
Clinical Care Transition Specialist / Registered Nurse - Oklahoma City
Option Care Health
Oklahoma City, Oklahoma
Executive Leadership & C-Suite
Program Management
Project Management
$73k.17 - $121k.94/yr
5,001-10,000

Have you applied for this role?

Choice Health at Home
Home Health RN Clinical Manager
We won't show you this job again
Choice Health at Home
Added 6d ago
Home Health RN Clinical Manager
Choice Health at Home
Oklahoma City, Oklahoma
Executive Leadership & C-Suite
Program Management
Project Management
Managed Registered Nurses (RNs)
1,001-5,000

Have you applied for this role?

See All 37 Clinical Registered Nurse Jobs in Oklahoma

Find roles in Oklahoma that match your experience and apply in just a few clicks.

Find Jobs

Clinical Registered Nurse Jobs by City in Oklahoma

Where Oklahoma roles are concentrated, by current openings.

Oklahoma City
15 jobs
Tulsa
7 jobs
Durant
2 jobs
Norman
2 jobs
Sapulpa
2 jobs
Ada
1 job
Idabel
1 job
Owasso
1 job
Stroud
1 job

Clinical Registered Nurse Job Market in Oklahoma

A snapshot from current Oklahoma openings, updated as new roles post.

Who's Hiring

Enhabit Home Health & Hospice
Enhabit Home Health & Hospice9 open roles
INTEGRIS Health
INTEGRIS Health4 open roles
Ascension
Ascension2 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What Oklahoma Employers Look For

The qualifications that appear most often in clinical registered nurse jobs across Oklahoma.

  • Active registered nurse license issued or recognized by the Oklahoma Board of Nursing
  • Current BLS certification from the American Heart Association required at hire
  • Associate or bachelor of science in nursing from an accredited program
  • Minimum one year of acute care or clinical nursing experience preferred
  • Demonstrated competency in electronic health record systems such as Epic or Cerner
  • ACLS or PALS certification required for critical care, emergency, and pediatric roles

Clinical Registered Nurse Jobs in Oklahoma: Frequently Asked Questions

How do you become a clinical registered nurse in Oklahoma?

You become a clinical registered nurse in Oklahoma by completing an accredited associate or bachelor of science in nursing program, passing the NCLEX-RN licensing exam, and applying for an active license through the Oklahoma Board of Nursing. Oklahoma participates in the Nurse Licensure Compact, so nurses holding a multistate license from another compact state can work in Oklahoma without obtaining a separate state license. Most hospital employers also require current BLS certification before your first shift.

How much do clinical registered nurses make in Oklahoma?

Clinical registered nurses in Oklahoma earn a median of about $82,920 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,530 for the lowest 10% to over $106,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical registered nurses in Oklahoma?

Employers hiring clinical registered nurses in Oklahoma right now include Enhabit Home Health & Hospice, INTEGRIS Health, and Ascension, based on current listings on Migrate Mate as of August 2026. Oklahoma's largest acute care systems, including those anchored in the Oklahoma City and Tulsa metros, tend to post the most consistent volume across specialties and experience levels.

Which Oklahoma cities have the most clinical registered nurse jobs?

Oklahoma City, Tulsa, and Durant have the most clinical registered nurse openings in Oklahoma. Oklahoma City leads due to its dense concentration of major health systems, academic medical centers, and specialty hospitals, while Tulsa's strong base of regional medical centers and Lawton's military and community hospital presence drive steady hiring in those markets.

Are there remote clinical registered nurse jobs in Oklahoma?

Yes, but they're rare. Clinical registered nursing is fundamentally a hands-on, patient-facing role, so most positions require an on-site presence. About 20% of clinical registered nurse openings tied to Oklahoma are remote or hybrid as of August 2026, and those roles are almost exclusively in case management, utilization review, or telephone triage functions rather than direct bedside care.

How can I get hired as a clinical registered nurse in Oklahoma with little or no experience?

The most realistic entry path is a new graduate nurse residency program, which large Oklahoma employers such as INTEGRIS Health, OU Health, and Ascension St. John run specifically for nurses with no clinical work history after licensure. These structured residencies typically place new RNs in med-surg or telemetry units, which are the most accessible specialties for early-career nurses. Candidates who secure a clinical practicum or extern position at an Oklahoma hospital while still in nursing school significantly improve their hiring odds at that same facility after passing the NCLEX-RN.

Where can I find and apply to clinical registered nurse jobs in Oklahoma?

You can find and apply to clinical registered nurse jobs in Oklahoma on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the listings to find roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.

See All 37 Clinical Registered Nurse Jobs in Oklahoma

Find roles in Oklahoma that match your experience and apply in just a few clicks.

Find Jobs