Clinical Research Assistant Jobs in North Carolina
Clinical Research Assistant jobs in North Carolina are concentrated in the Research Triangle, Charlotte, and Winston-Salem, where institutions like Duke Health, UNC Health, and Wake Forest Baptist Medical Center anchor steady demand for coordinators, data collectors, and regulatory support staff at every level from entry to senior. The most in-demand specialties include oncology trials, cardiovascular research, and Phase II through Phase IV drug studies. See the openings below and apply to the ones that match your experience.
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Duties:
- Coordinate and schedule subject visits within study/subject specific windows per protocol guidelines.
- Prepare visit-specific documentation and charts for Clinical Research Coordinator.
- Observe Coordinator in patient care and management.
- Assist Coordinator in monitoring subject flow and assist in subject care and management.
- Observe, assist, collect and record all necessary data for follow up (e.g. adverse events, concomitant medications, etc.) study visits (Phase 2 & 3; NO Gene Therapy).
- Transcribe subject study information from source documents to the Electronic Case Report Forms.
- Administer all mandatory questionnaires to study subjects.
- Set up, prepare subject, and conduct electrocardiograms (ECG) on subjects as required per study protocol.
- Promptly request all necessary medical records for Serious Adverse Event Reporting.
- Process and ship laboratory biological samples for analysis.
- Perform intraocular pressure checks after injections.
- Perform trial frame refraction and Early Treatment Diabetic Retinopathy Study (ETDRS) visual acuity testing (For Investigator Sponsored Trials (IST)s only, at selected sites).
- Inform subjects and obtain written re-consents in regard to Informed Consent Form (ICF)’s (selected studies)
- Observe and assist scribe in ocular exams for doctors and confirm appropriate treatment per protocol.
- Perform other duties as assigned.
- Obtain any applicable additional/required sponsor training and/or certifications.
Minimum Qualifications:
- High School diploma or the equivalent, with significant relevant experience.
- College degree preferred.
- Ophthalmic experience preferred.
- Effective oral and written communication.
- Delivers safe and appropriate care to patients in addition to the requirements outlined by study protocols.
See All 58 Clinical Research Assistant Jobs in North Carolina
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Find JobsClinical Research Assistant Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Clinical Research Assistant Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring


Top Industries Hiring
- Science & Research
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
- Staffing & Recruiting
- Consulting & Professional Services
What North Carolina Employers Look For
The qualifications that appear most often in clinical research assistant jobs across North Carolina.
- Bachelor's degree in life sciences, biology, nursing, or a closely related field
- Experience with clinical trial regulatory documentation including ICH-GCP guidelines
- Proficiency with electronic data capture systems such as REDCap or Medidata Rave
- Certification as a Clinical Research Coordinator or equivalent credential preferred
- Strong understanding of IRB submission and study protocol compliance requirements
- Ability to obtain and maintain current Good Clinical Practice training certification
Clinical Research Assistant Jobs in North Carolina: Frequently Asked Questions
How do you become a clinical research assistant in North Carolina?
Most clinical research assistant positions in North Carolina require a bachelor's degree in a life science, nursing, or public health field. North Carolina does not issue a state-specific license for this role, but employers widely expect Good Clinical Practice certification and, increasingly, a credential from the Society of Clinical Research Associates or the Association of Clinical Research Professionals. Starting as a research coordinator assistant or clinical data assistant at a Triangle-area academic medical center is the most common entry path.
Which companies hire clinical research assistants in North Carolina?
Employers hiring clinical research assistants in North Carolina right now include Fortrea, Optimapharm d.o.o., and Thermo Fisher Scientific, based on current listings on Migrate Mate as of August 2026. The Research Triangle's concentration of contract research organizations, biotechnology firms, and academic health systems makes North Carolina one of the country's most active markets for this role.
Which North Carolina cities have the most clinical research assistant jobs?
Durham, Raleigh, and North Carolina account for the largest share of clinical research assistant openings in North Carolina. The Research Triangle anchors the market through its dense cluster of academic medical centers, NIH-funded research programs, and contract research organizations, while Charlotte's growing hospital systems and Winston-Salem's Wake Forest research enterprise drive demand in those metros.
Are there remote clinical research assistant jobs in North Carolina?
Yes, but they are limited, since the role often requires on-site patient contact, specimen handling, and in-person regulatory meetings. About 54% of clinical research assistant openings tied to North Carolina are remote or hybrid as of August 2026, with most flexibility concentrated in data entry, regulatory document review, and remote monitoring responsibilities rather than direct patient-facing work.
How can I get hired as a clinical research assistant in North Carolina with little or no experience?
The most realistic entry path is applying for a clinical research coordinator trainee or research assistant I role at a Research Triangle academic medical center such as Duke Health or UNC Health, both of which run structured onboarding programs for candidates without prior trial experience. Lateral moves from roles like medical assistant, phlebotomist, or clinical data specialist are common. Completing a free Good Clinical Practice certification and any SOCRA coursework before applying gives candidates a measurable edge.
Where can I find and apply to clinical research assistant jobs in North Carolina?
You can find and apply to clinical research assistant jobs in North Carolina on Migrate Mate, which lists current North Carolina openings across research sites, hospital systems, and contract research organizations. Search for roles that match your experience level and location, then apply directly to the ones that fit.
See All 58 Clinical Research Assistant Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
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