Clinical Research Nurse Jobs in District of Columbia
Clinical Research Nurse jobs in District of Columbia are concentrated in Washington, D.C.'s dense corridor of federal agencies, academic medical centers, and nonprofit research organizations, with hiring activity across the full range from study coordinator to principal investigator support. NIH Clinical Center, MedStar Health, and Children's National Hospital are among the most established employers in the region, consistently recruiting for roles in oncology trials, infectious disease research, and rare disease studies. Demand is steady, driven by the area's outsized federal research funding and proximity to FDA and NIH campuses. Find a role that fits below and apply directly.
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ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster.
As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers.
The Sr. Clinical Research Associate (Sr. CRA) will be responsible for performing investigative site management and monitoring activities throughout the clinical trial lifecycle. This Sr. CRA role will support the client's Oncology clinical trials to ensure data integrity, subject safety, and inspection readiness at the clinical investigative sites.
Responsibilities:
Perform site management activities to support the client's Oncology site success and maintain a continuous state of inspection readiness
Act as the primary contact and facilitate efficient communications between the client's clinical trial team and the sites
Perform remote and on-site monitoring/co-monitoring visits (Site Qualification Visits, Site Initiation Visits, Interim Monitoring Visits and Close-Out Visits) to ensure data integrity and subject safety in the client's trials
May perform oversight activities to assess monitoring quality and train/mentor less experienced CRAs
Promptly document monitoring activities and submit/approve visit reports
Manage site essential document collection and TMF reconciliation with site files
Support sites with local Institutional Review Board (IRB)/Ethics Committee (EC) submissions and confirm approvals
Regularly review site Key Risk Indicator (KRI) metrics, issues and action items to detect trends and ensure prompt resolution
Independently determine root causes and develop/implement site Corrective Action and Preventive Action (CAPA) plans
Deliver training to ensure sites comply with the protocol, Standard Operating Procedures (SOPs), Good Clinical Practices (GCPs) and regulations
Support sites and the client's regulatory inspections
Contribute to site identification; drive site feasibility and qualification progress; and support site activation activities
Lead site engagement initiatives and foster relationships with key Oncology sites and networks
Qualifications
Bachelor’s degree (scientific field preferred)
5+ years monitoring clinical trials independently conducting on-site and remote monitoring visits. Atleast 2 years monitoring solid tumor clinical trials.
1+ years early development trial experience
Solid tumor clinical trial experience is required
Experience utilizing Veeva systems is highly preferred
Demonstrated experience developing/maintaining site relationships and securing compliance
Expertise in GxPs and Oncology monitoring techniques (including Risk-Based Monitoring) and terminology
Experience collaborating with sites from initial engagement through close-out phases
Experience activating sites
Experience training site staff
Experience supporting sites and/or sponsors in regulatory inspections
Experience working within a Functional Services (or in-house) monitoring model is preferred
Willing to travel up to 75%
Employment with ICON is contingent upon having the legal right to work in the country where the role is based.
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our careers site to read more about the benefits ICON offers.
Inclusion and Accessibility
ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.
If you require reasonable accommodations during the recruitment process, please let us know or submit a request here.
Salary Range
$110,520.00-$138,150.00See All 27 Clinical Research Nurse Jobs in District of Columbia
Find roles in District of Columbia that match your experience and apply in just a few clicks.
Find Clinical Research Nurse JobsClinical Research Nurse Jobs by City in District of Columbia
Where District of Columbia roles are concentrated, by current openings.
Clinical Research Nurse Job Market in District of Columbia
A snapshot from current District of Columbia openings, updated as new roles post.
Who's Hiring
- Children's National Hospital17

- Georgetown University3

- Johns Hopkins University3

- The Henry M. Jackson Foundation for the Advancement of Military Medicine2

- Parexel1

Top Industries Hiring
- Healthcare & Medical Services19
- Education5
- Science & Research2
- Biotechnology & Pharmaceuticals1
What District of Columbia Employers Look For
The qualifications that appear most often in clinical research nurse jobs across District of Columbia.
- Active RN license issued or recognized by the District of Columbia Board of Nursing
- Bachelor of Science in Nursing degree from an accredited program
- Minimum two years of clinical nursing experience in a hospital or ambulatory setting
- Experience with clinical trial protocols, informed consent, and GCP guidelines
- CCRN, OCN, or CCRC certification preferred by most research-focused employers
- Proficiency in electronic data capture systems such as REDCap or Medidata Rave
Clinical Research Nurse Jobs in District of Columbia: Frequently Asked Questions
How do you become a clinical research nurse in District of Columbia?
You must hold an active RN license in the District of Columbia, issued by the D.C. Board of Nursing after passing the NCLEX-RN. Most employers in the region expect a BSN at minimum, and many academic medical centers tied to Georgetown, George Washington, or Howard University prefer candidates with graduate coursework. From there, gaining clinical trial experience through a research assistant or study coordinator role at an NIH-affiliated institution or large health system is the most direct path into a dedicated clinical research nurse position.
Which companies hire clinical research nurses in District of Columbia?
Companies currently hiring clinical research nurses in District of Columbia include Children's National Hospital, Georgetown University, and Johns Hopkins University, per current listings on Migrate Mate as of July 2026. The D.C. region's concentration of federally funded research programs and large academic health systems means clinical research nurse demand tends to remain active across both government-affiliated and private institutional employers throughout the year.
Which District of Columbia cities have the most clinical research nurse jobs?
Washington account for the largest share of clinical research nurse openings in District of Columbia. Washington, D.C. itself drives the bulk of activity, anchored by NIH, FDA, and major academic medical centers, while nearby areas reflect the broader National Capital Region research ecosystem where large health systems and contract research organizations maintain significant clinical operations.
Are there remote clinical research nurse jobs in District of Columbia?
Yes, but they're rare. Clinical research nursing is fundamentally a hands-on role requiring direct patient contact for assessments, specimen collection, and protocol procedures. About 22% of clinical research nurse openings tied to District of Columbia are remote or hybrid as of July 2026, and the remote share tends to be limited to roles focused on data review, regulatory document management, or remote patient monitoring components of decentralized trials.
How can I get hired as a clinical research nurse in District of Columbia with little or no experience?
The most realistic entry point is a research coordinator or clinical research associate role at one of D.C.'s large research institutions, which often accept candidates with bedside nursing experience and no prior trial background. NIH Clinical Center runs nurse residency and onboarding pathways that introduce clinical staff to GCP and protocol management. MedStar Health and Children's National also recruit new-to-research nurses into study team support roles. Earning a Good Clinical Practice certification before applying signals readiness and helps offset a limited research resume.
Where can I find and apply to clinical research nurse jobs in District of Columbia?
You can find and apply to clinical research nurse jobs in District of Columbia on Migrate Mate, which lists current openings in the region. Search the available roles, identify the ones that fit your experience and specialty area, and apply directly to the positions that match.
See All 27 Clinical Research Nurse Jobs in District of Columbia
Find roles in District of Columbia that match your experience and apply in just a few clicks.
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