Human Resources Associate Jobs in Massachusetts
Human Resources Associate jobs in Massachusetts are in steady demand across the state's deep base of healthcare systems, higher education institutions, financial services firms, and biotechnology companies, with openings at every level from entry-level coordinator to senior HR generalist. Boston, Cambridge, and Worcester anchor the largest share of hiring, and established employers like Mass General Brigham, Liberty Mutual, and Fidelity Investments maintain consistent HR teams that recruit regularly. The most sought-after specialties in Massachusetts listings are talent acquisition support, employee relations, and HRIS administration. Scan the live roles below and apply to whichever ones fit.
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Alpha-9 Oncology is seeking an experienced and strategic Director, Total Rewards & People Operations to lead the design, execution, and administration of our global rewards and people operations programs. As Alpha-9 continues to scale with operations in the United States and Canada, this role will serve as a key partner to People, Finance, Legal, and business leaders to ensure our compensation, benefits, HR operations, compliance, and employee experience programs are competitive, compliant, and aligned with our business strategy.
Reporting to the Chief People Officer, you will shape and evolve Alpha-9's total rewards philosophy while also providing operational leadership across HR systems, leave administration, employee lifecycle processes, and Canadian employment compliance. This role offers a unique opportunity to build scalable infrastructure and influence organizational growth while ensuring employees have an exceptional experience throughout their employment journey. This role is based in Boston, MA.
How You’ll Contribute
- Define and execute Alpha-9's global total rewards strategy, including compensation, equity, benefits, retirement, wellness, and recognition programs.
- Lead annual compensation processes, including merit planning, promotions, market adjustments, bonus administration, and equity review cycles.
- Drive compensation benchmarking, job architecture, career frameworks, and market analyses to ensure competitive and equitable pay practices.
- Oversee all employee benefits programs in the U.S. and Canada, including broker relationships, renewals, plan design, open enrollment, and employee communications.
- Lead People Operations processes across the employee lifecycle, including onboarding, offboarding, employee records management, policy administration, and workforce reporting.
- Serve as the primary owner of Rippling administration, configuration, data integrity, process optimization, reporting, and vendor management.
- Oversee leave of absence administration, including FMLA, PFML, short-term disability, long-term disability, parental leave, ADA accommodations, and applicable Canadian leave programs.
- Ensure compliance with U.S. and Canadian employment laws related to compensation, benefits, pay transparency, employment standards, payroll, leaves, and HR policies.
- Partner with Legal and external advisors on immigration, cross-border employment matters, employee mobility, and workforce compliance initiatives.
- Develop and maintain HR policies, employee handbooks, standard operating procedures, and governance practices across multiple jurisdictions.
- Provide strategic support during organizational changes, relocations, workforce planning initiatives, and employee transitions.
- Analyze workforce, compensation, benefits, and HR operations data to identify trends and inform leadership decisions.
- Build and mentor scalable People Operations capabilities that support Alpha-9's continued growth.
The Skills You Bring
- B.A. in Human Resources, Business Administration, Finance, or a related field.
- 10+ years of progressive HR experience with significant expertise in Total Rewards, Benefits, Compensation, and HR Operations.
- Demonstrated experience designing and administering compensation, bonus, equity, and benefit programs within high-growth biotechnology or life sciences organizations.
- Strong knowledge of compensation benchmarking, salary structures, job architecture, and market pricing methodologies.
- Deep understanding of U.S. and Canadian employment laws impacting compensation, benefits, leave administration, and HR compliance.
- Hands-on experience administering and optimizing HRIS platforms.
- Expertise managing employee leave programs, accommodations processes, disability programs, and related vendor relationships.
- Demonstrated ability to operate both strategically and tactically in a fast-paced, resource-constrained environment.
- Exceptional judgment, discretion, and ability to manage sensitive information.
- Strong project management and change management capabilities with a focus on creating scalable processes.
Compensation
Alpha-9 Oncology is committed to pay transparency and equitable compensation. The salary range for this position represents the Company’s good-faith estimate of base compensation at the time of posting, established using external market data and internal benchmarking. Final compensation will be determined based on experience, qualifications, education, and internal equity.
This role is eligible for an annual bonus, equity participation, and a comprehensive benefits package.
Per Year Salary Range
$213,000 - $245,000 USD
Company Summary
Alpha-9 Oncology is a clinical-stage biotechnology company pioneering radiopharmaceutical innovation for solid tumors. Our proprietary scaffolds, composed of optimized binders, linkers, chelators, and radioisotopes, enable targeted radiation delivery to cancer cells, minimizing harm to surrounding healthy tissue. Focusing on innovative targeting moieties, we develop molecules tailored for precise tumor targeting.
Our comprehensive platform integrates imaging and therapeutic studies to ensure effective radiation delivery and improved patient outcomes. With a robust pipeline entering clinical trials and strong support from leading healthcare investors, Alpha-9 is positioned for rapid growth and advancement in cancer therapy.
More about Alpha-9 Oncology
Alpha-9 Oncology is committed to fostering a diverse and inclusive workplace and is proud to be an Equal Opportunity Employer. We provide employment opportunities to all qualified applicants without regard to race, ethnicity, religion, age, sex, gender identity or expression, sexual orientation, disability, marital status, family status, national origin, or any other characteristic protected by applicable federal, provincial, or local laws where we operate.
We are dedicated to providing reasonable accommodations to qualified applicants and employees to ensure that everyone can perform their essential job functions in an inclusive environment. For inquiries regarding accommodations in the hiring process or for current employees, please contact a member from our Talent Acquisition team.
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Find JobsHuman Resources Associate Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Human Resources Associate Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Science & Research
- Hospitality & Tourism
- Technology & Software
- Healthcare & Medical Services
What Massachusetts Employers Look For
The qualifications that appear most often in human resources associate jobs across Massachusetts.
- Bachelor's degree in human resources, business administration, or a related field required
- PHR or SHRM-CP certification preferred by many Massachusetts employers
- One to three years of experience in HR coordination, recruiting, or generalist support
- Proficiency with HRIS platforms such as Workday, ADP, or SAP SuccessFactors
- Working knowledge of Massachusetts employment law and MCAD compliance requirements
- Strong communication skills with experience supporting employee onboarding and benefits administration
Human Resources Associate Jobs in Massachusetts: Frequently Asked Questions
How do you become a human resources associate in Massachusetts?
Most employers require a bachelor's degree in human resources, business, or a related field as the starting point. Massachusetts does not require a state-issued license to work as a human resources associate, but earning the SHRM-CP or PHR certification is widely expected at mid-size and large employers in the state. Many candidates enter through HR coordinator or administrative roles at healthcare systems, universities, or financial services firms before moving into associate-level positions.
Which companies hire human resources associates in Massachusetts?
Employers hiring human resources associates in Massachusetts right now include Target, Smithsonian Astrophysical Observatory, and PUMA, based on current listings on Migrate Mate as of October 2026. Massachusetts's large healthcare networks, asset management firms, and research universities tend to post the most consistent volume of HR associate openings throughout the year.
Which Massachusetts cities have the most human resources associate jobs?
Boston, Waltham, and Cambridge account for the largest concentration of human resources associate openings in Massachusetts. Boston and Cambridge dominate because of the dense cluster of hospitals, biotech employers, and financial institutions headquartered there, while Worcester draws consistent demand from UMass Memorial Health, Hanover Insurance, and a growing network of regional manufacturers and healthcare organizations.
Are there remote human resources associate jobs in Massachusetts?
Yes, and they are fairly common given how much of the role involves document management, HRIS work, and employee communications that can be done off-site. About 49% of human resources associate openings tied to Massachusetts are remote or hybrid as of October 2026, reflecting the desk-based nature of most HR associate duties. Tasks like in-person onboarding, benefits fairs, and investigations tend to anchor the roles that remain fully on-site.
How can I get hired as a human resources associate in Massachusetts with little or no experience?
The most realistic entry path is an HR coordinator or HR assistant role at one of Massachusetts's large healthcare systems or universities, where structured onboarding programs and clear promotion tracks exist for candidates without prior HR titles. Mass General Brigham, Boston Children's Hospital, UMass Amherst, and Northeastern University all run new-grad and early-career programs that feed into associate-level HR roles. Candidates coming from adjacent work in payroll, benefits, or office administration have a strong lateral case, and completing the SHRM-CP or an aPHR certification while job searching signals genuine commitment to Massachusetts hiring managers.
Where can I find and apply to human resources associate jobs in Massachusetts?
You can find and apply to human resources associate jobs in Massachusetts on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the listings, identify the roles that match your background and target location, and apply directly to whichever ones fit your experience and goals.
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