IT Systems Specialist Jobs in North Carolina
IT Systems Specialist jobs in North Carolina are open across Raleigh, Charlotte, and Durham and other North Carolina metros, with employers like Infojini, Davidson College, and Dentsply Sirona hiring at every experience level. Find a role that fits below and apply directly.
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At KBI Biopharma, we are advancing science and accelerating breakthroughs. As a global leader in biopharmaceutical development and manufacturing, we empower life science companies to bring new medicines and vaccines to the world faster. Explore your potential at KBI, where innovation meets impact.
IT Systems Specialist II
Responsibilities:
- Advanced Technical Support: Handle more complex technical issues that are escalated from IT Technician and IT Systems Specialist 1, providing in-depth troubleshooting and resolution.
- System Configuration: Configure and maintain user systems, including operating system settings and application configurations.
- Network Support: Identify and resolve network connectivity issues, including wireless and VPN connections.
- Mobile Device Management: Setup, configure, and troubleshoot mobile devices and ensure they comply with security policies.
- User Account Management: Perform more advanced user account management tasks, including setting permissions and configuring user roles.
- Software Deployment: Manage the deployment of software updates and patches to end-user systems.
- Documentation and Training: Create detailed support documentation and conduct training sessions for end users on new technologies and best practices.
- Incident Management: Track and manage incidents and service requests, ensuring timely resolution and escalation when necessary.
- Hardware Troubleshooting: Diagnose and resolve more complex hardware issues, coordinating repairs or replacements as needed.
- Vendor Coordination: Collaborate with vendors to resolve hardware and software issues, and manage vendor support services for end-user technology.
- Systems Analysis and Design: Engage in the analysis of user needs and the design of new system functionalities to improve and optimize IT systems.
- System Development: Participate in the development and implementation of new software applications and tools to enhance system capabilities.
Requirements
- High School diploma or equivalent, Bachelor’s degree preferred, with a minimum of 3 years experience in IT Help Desk related work.
- 3-5 years of Advanced Hardware Knowledge: Deeper understanding of troubleshooting and repairing a wide range of hardware issues.
- System Configuration: Ability to configure and maintain operating systems (Windows, macOS) and user applications.
- Advanced Networking: Skills in troubleshooting more complex network issues, understanding wireless networks, VPNs, and network security basics.
- Mobile Device Management: Proficiency in managing and securing mobile devices, including familiarity with MDM solutions.
- Advanced User Account Management: Skills in managing user accounts, permissions, and roles in Active Directory.
- Software Deployment: Ability to deploy software updates and patches using tools such as SCCM, Intune, or other software deployment systems.
- Remote Support Tools: Proficiency in using remote support tools to assist users.
- Vendor Coordination: Skills in coordinating with vendors for hardware repairs, software issues, and support services.
- Software development skills: Basic knowledge of software development principles and ability to contribute to the creation of new applications and tools.
Salary Range: $63,000 - $86,900
Salary range provided per current averages and expectations. The salary and job title for this opening will be based on the selected candidate’s qualifications and experience and may be outside this range. KBI has a robust total rewards strategy which includes an annual bonus structure for all employees, medical, dental, and vision coverage, paid PTO and holidays, 401K matching with 100% vesting in 60 days and employee recognition programs.
About KBI:
KBI Biopharma, Inc., a JSR Life Sciences company, is a global contract development and manufacturing organization (CDMO) providing fully integrated and accelerated drug development and biologics manufacturing services to life science companies. KBI supports its 500+ customers in advancing more than 160 drug candidates from preclinical and clinical stages to market, including the manufacture of ten commercial products. Recognized for quality manufacturing, KBI delivers robust process development and cGMP manufacturing services across its six global locations in the USA and Europe.
KBI is a proud EEO/AA employer dedicated to building a diverse and inclusive workforce. We believe that innovation thrives in an environment where all voices are heard and valued. That's why we actively seek individuals from all backgrounds – regardless of race, color, national origin, religion, gender, gender identity, sexual orientation, age, disability, or veteran status – and strongly encourage all qualified candidates to apply and bring their unique perspectives to our team.
KBI Biopharma, Inc. is an EEO/AA employer and actively seeks to diversify its work force. Therefore, all qualified applicants, regardless of race, color, national origin, religion, gender, gender identity, sexual orientation, age, disability or veteran status, are strongly encouraged to apply.
I understand that neither the completion of this application nor any other part of my consideration for employment establishes any obligation for KBI Biopharma, Inc. to hire me. If I am hired, I understand that either KBI Biopharma, Inc. or I can terminate my employment at any time and for any reason, with or without cause and without prior notice. I understand that no representative of KBI Biopharma, Inc. has the authority to make any assurance to the contrary.
I attest with my signature below that I have given to KBI Biopharma, Inc. true and complete information on this application. No requested information has been concealed. I authorize KBI Biopharma, Inc. to contact references provided for employment reference checks. If any information I have provided is untrue, or if I have concealed material information, I understand that this will constitute cause for the denial of employment or immediate dismissal.
See All 18 IT Systems Specialist Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find IT Systems Specialist JobsIT Systems Specialist Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
IT Systems Specialist Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
- Infojini5

- Davidson College1

- Dentsply Sirona1

- ECR Software Corporation1

- HCLTech1

Top Industries Hiring
- Technology & Software11
- Consulting & Professional Services3
- Biotechnology & Pharmaceuticals1
- Food & Beverage1
- Medical Devices1
What North Carolina Employers Look For
The qualifications that appear most often in IT systems specialist jobs across North Carolina.
- Proficiency with Active Directory, Group Policy, and Windows Server administration
- Experience supporting and troubleshooting enterprise endpoints running Windows and macOS
- Familiarity with networking fundamentals including TCP/IP, DNS, DHCP, and VPN configurations
- CompTIA A+, Network+, or a Microsoft certification such as MS-900 or MD-102
- Experience with a helpdesk or ITSM ticketing platform such as ServiceNow, Jira Service Management, or Zendesk
- Associate or bachelor's degree in information technology, computer science, or a related field, or equivalent hands-on experience
IT Systems Specialist Jobs in North Carolina: Frequently Asked Questions
How many IT systems specialist jobs are there in North Carolina?
There are 18+ IT systems specialist openings in North Carolina on Migrate Mate as of June 2026, with the most roles in Raleigh, Charlotte, and Durham. New positions post regularly as employers across North Carolina hire.
Which North Carolina cities have the most IT systems specialist jobs?
Raleigh, Charlotte, and Durham have the most IT systems specialist openings in North Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire IT systems specialists in North Carolina?
Employers hiring IT systems specialists in North Carolina include Infojini, Davidson College, and Dentsply Sirona, based on current listings on Migrate Mate as of June 2026.
Are there remote IT systems specialist jobs in North Carolina?
Yes. About 0% of IT systems specialist openings tied to North Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in North Carolina metros.
How do I apply for IT systems specialist jobs in North Carolina?
You can apply to IT systems specialist jobs in North Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred North Carolina location, then apply to each one that fits.
See All 18 IT Systems Specialist Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find IT Systems Specialist Jobs