Oncology Registered Nurse Jobs in Oklahoma
Oncology Registered Nurse jobs in Oklahoma are concentrated in Oklahoma City and Tulsa, where major systems like OU Health, Integris Health, and Saint Francis Health System consistently hire across inpatient oncology, infusion therapy, and bone marrow transplant units. Demand extends to cancer center roles at institutions affiliated with the Stephenson Cancer Center, one of the region's anchor programs. Openings range from new graduate positions to senior and charge nurse roles, with hematology-oncology and radiation oncology among the most sought-after specialties statewide. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 20+ Oncology Registered Nurse jobs









Position Title:
RN - Registered Nurse - GI/Colorectal Oncology Clinic - Stephenson Cancer CenterDepartment:
SCC Multi-Disciplinary ClinicJob Description:
This position may be filled as an Ambulatory RN Level 1 or 2, depending on individual experience, education, and other qualifications.
Special Benefits:
Student loan repayment up to $25,000
Relocation assistance if moving 100+ miles
General Description: An OU Health Registered Nurse (RN) Ambulatory I works under general supervision, providing the highest quality of care in an ambulatory setting to patients with health problems ranging from simple to complex. They model the OU Health Way, as evident in their work output and interactions with employees and patients, through living OU Health’s core values of putting Patients First , pursuing Relentless Excellence , showing Integrity , seeking Inclusion for all staff and patients, always Learning , and valuing Teamwork .
RN I represents the nurse who is a novice or an advanced beginner advancing to competent. While advancing from novice to competent, the nurse relies on rules rather than principles which are independent of specific situations. The advanced beginner may have enough real experience to begin to formulate principles.
Essential Responsibilities
- Aligns behaviors with OU Health values and maintains nursing professional practice standards
- Assumes responsibility for an assigned patient, group of patients, or patients to be seen by service/clinic.
- Documents patient responses to nursing interventions and prescribed medical treatments, noting all changes in physician order on assigned patients.
- Assists physician in the examination of patients and in performing minor diagnostic procedures and treatment.
- Obtains and monitors physiological data of patients, observes the physiological manifestations of patients, and intervenes when necessary.
- Administers medication as prescribed.
- Initiates, regulates and monitors intravenous infusions and blood products.
- Delivers patient care safely and competently.
- Resolves patient complaints in a timely manner in accordance with policy and in collaboration with support staff.
- Informs patient and family of clinic and/or unit procedures and shares care plan during the time of care and at the time of discharge.
- Makes referrals regarding patient care needs to appropriate personnel.
- Fosters a growth mindset through seeking mentorship, remaining open to coaching and feedback, and maintaining professional certification(s)/licensure in order to perpetually develop and uphold the skills required for proficiency within the nursing profession.
- Develops a professional career plan and establishes personal, performance goals in alignment with enterprise-wide metrics, frequently measuring progress with department leadership.
- Fosters an inclusive workforce where individual differences are valued and maximized to achieve OU Health’s winning aspiration.
- Delegates tasks to clinical support staff as needed.
- Performs other duties as assigned.
*Minimum Qualifications (RN I):
Education: Associate's or Bachelor's Degree in Nursing.
Experience: 0-3 years of experience in patient care as a Registered Nurse.
License/Certification/Registration:
- Current Registered Nurse License (RN License issued by the Oklahoma State Board of Nursing, or a current multistate compact Registered Nurse (eNLC)).
- Basic Life Support (American Heart Association) certification required upon hire.
*Minimum Qualifications (RN II):
Education: Associate's or Bachelor's Degree in Nursing.
Experience: 3+ years of experience in patient care as a Registered Nurse required.
License/Certification/Registration:
- Current Registered Nurse License (RN License issued by the Oklahoma State Board of Nursing, or a current multistate compact Registered Nurse (eNLC)).
- Basic Life Support (American Heart Association) certification required upon hire.
- Specialty certification(s) preferred.
Knowledge, Skills, Abilities
- Knowledge of basic professional nursing theory, practices, techniques, and procedures.
- Ability to organize, plan, coordinate, and evaluate nursing services and apply nursing techniques.
- Ability to maintain civility and good working relationships with other employees.
- Ability to respond effectively to cultural and language needs of patients and visitors.
- Skilled in computer applications designed to ensure quality and safety measures for patients.
- Ability to establish and maintain integrity and trust with patients by advocating in the patient’s best interest.
- Ability to engage and manage conflicts and disagreements in a constructive manner.
- Ability to maintain compliance accreditation with local, state, and federal regulatory standards.
- Ability to foster an inclusive workplace where diversity and individual differences are valued and maximized to achieve the vision and mission of the organization.
- Strong written and oral communication skills characterized by candor, openness, integrity, and ability to be diplomatic.
Current OU Health Employees - Please click HERE to login.
OU Health is an equal opportunity employer. We offer a comprehensive benefits package, including PTO, 401(k), medical and dental plans, and many more. We know that a total benefits and compensation package, designed to meet your specific needs both inside and outside of the work environment, create peace of mind for you and your family.
See All 20 Oncology Registered Nurse Jobs in Oklahoma
Find roles in Oklahoma that match your experience and apply in just a few clicks.
Find JobsOncology Registered Nurse Jobs by City in Oklahoma
Where Oklahoma roles are concentrated, by current openings.
Oncology Registered Nurse Job Market in Oklahoma
A snapshot from current Oklahoma openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Education
What Oklahoma Employers Look For
The qualifications that appear most often in oncology registered nurse jobs across Oklahoma.
- Active RN license issued or recognized by the Oklahoma Board of Nursing
- Oncology Nursing Certification (OCN) required or preferred by most employers
- Minimum one to two years of oncology or medical-surgical nursing experience
- Current BLS and ACLS certification from the American Heart Association
- Experience administering chemotherapy and managing oncology-related adverse effects
- Proficiency with electronic health record systems, commonly Epic or Cerner
Oncology Registered Nurse Jobs in Oklahoma: Frequently Asked Questions
How do you become a oncology registered nurse in Oklahoma?
You must first earn an Associate Degree in Nursing or a Bachelor of Science in Nursing, then pass the NCLEX-RN to obtain licensure through the Oklahoma Board of Nursing. Oklahoma participates in the Nurse Licensure Compact, so nurses licensed in other compact states may practice without a separate state license. Most employers then require at least one year of clinical experience before moving into an oncology-specific role, and many encourage pursuing the Oncology Nursing Certification once eligible.
How much do oncology registered nurses make in Oklahoma?
Oncology registered nurses in Oklahoma earn a median of about $82,920 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,530 for the lowest 10% to over $106,390 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire oncology registered nurses in Oklahoma?
Companies currently hiring oncology registered nurses in Oklahoma include OU Health, American Traveler, and SSM Health, per current listings on Migrate Mate as of August 2026. Oklahoma's largest health systems, including those anchored in Oklahoma City and Tulsa, drive the majority of consistent oncology nursing openings across inpatient, outpatient, and infusion settings.
Which Oklahoma cities have the most oncology registered nurse jobs?
Oklahoma City and Tulsa have the most oncology registered nurse openings in Oklahoma. Oklahoma City leads because of its dense concentration of major health systems and the Stephenson Cancer Center, while Tulsa's demand is driven by Saint Francis Health System and Cancer Treatment Centers of America, drawing consistent oncology hiring across both inpatient and outpatient settings.
How can I get hired as a oncology registered nurse in Oklahoma with little or no experience?
The most realistic entry path is applying to a new graduate nurse residency program at a large Oklahoma health system such as OU Health or Integris Health, both of which run structured residencies that include oncology rotations. Candidates coming from medical-surgical, emergency, or critical care backgrounds are strong internal transfer candidates for oncology units. Earning a chemotherapy administration certificate through the Oncology Nursing Society before applying gives newer nurses a measurable credential that stands out to Oklahoma hiring managers.
Where can I find and apply to oncology registered nurse jobs in Oklahoma?
You can find and apply to oncology registered nurse jobs in Oklahoma on Migrate Mate, which lists current Oklahoma openings across health systems, cancer centers, and outpatient infusion clinics. Find roles that fit your experience and specialty area and apply directly to the employers posting them.
See All 20 Oncology Registered Nurse Jobs in Oklahoma
Find roles in Oklahoma that match your experience and apply in just a few clicks.
Find Jobs