Oncology Registered Nurse Jobs in Oklahoma
Oncology Registered Nurse jobs in Oklahoma are concentrated in Oklahoma City and Tulsa, where major systems like OU Health, Integris Health, and Saint Francis Health System consistently hire across inpatient oncology, infusion therapy, and bone marrow transplant units. Demand extends to cancer center roles at institutions affiliated with the Stephenson Cancer Center, one of the region's anchor programs. Openings range from new graduate positions to senior and charge nurse roles, with hematology-oncology and radiation oncology among the most sought-after specialties statewide. Find a role that fits below and apply directly.
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- Location: Tulsa, OK
- Facility: Ascension St. John Medical Center
- Department: Oncology Inpatient Hospice
- Schedule: Full-time day shift. Three 12-hour shifts.
- Comprehensive health coverage: medical, dental, vision, prescription coverage and HSA/FSA options
- Financial security & retirement: employer-matched 403(b), planning and hardship resources, disability and life insurance
- Time to recharge: pro-rated paid time off (PTO) and holidays
- Career growth: Ascension-paid tuition (Vocare), reimbursement, ongoing professional development and online learning
- Emotional well-being: Employee Assistance Program, counseling and peer support, spiritual care and stress management resources
- Family support: parental leave, adoption assistance and family benefits
- Other benefits: optional legal and pet insurance, transportation savings and more
- Implements and monitors patient care plans. Monitors, records and communicates patient condition as appropriate.
- Serves as a primary coordinator of all disciplines for well-coordinated patient care.
- Notes and carries out physician and nursing orders.
- Assesses and coordinates patient's discharge planning needs with members of the healthcare team.
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Required Credential(s):
- Registered Nurse credentialed from the Oklahoma Board of Nursing obtained prior to hire date or job transfer date.
- One or more of the following:
- Instructor specializing in Basic Life Support obtained within 1 Month (30 days) of hire date or job transfer date. American Heart Association or American Red Cross accepted.
- BLS Provider obtained within 1 Month (30 days) of hire date or job transfer date. American Heart Association or American Red Cross accepted.
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Preferred Credential(s):
- Certification specializing in Chemotherapy credentialed from the Oncology Nursing Society (ONS).
- Diploma from an accredited school/college of nursing required. OR Required professional licensure at time of hire.
Ascension is a leading nonprofit Catholic health system with a culture and associate experience grounded in service, growth, care and connection. We empower our 99,000+ associates to bring their skills and expertise every day to reimagining healthcare, together. Recognized as one of the Best 150+ Places to Work in Healthcare and a Military-Friendly Gold Employer, you'll find an inclusive and supportive environment where your contributions truly matter.
Equal employment opportunity employer
Ascension provides Equal Employment Opportunities (EEO) to all associates and applicants for employment without regard to race, color, religion, sex/gender, sexual orientation, gender identity or expression, pregnancy, childbirth, and related medical conditions, lactation, breastfeeding, national origin, citizenship, age, disability, genetic information, veteran status, marital status, all as defined by applicable law, and any other legally protected status or characteristic in accordance with applicable federal, state and local laws. For further information, view the EEO Know Your Rights (English) poster or EEO Know Your Rights (Spanish) poster.
Fraud prevention notice
Prospective applicants should be vigilant against fraudulent job offers and interview requests. Scammers may use sophisticated tactics to impersonate Ascension employees. To ensure your safety, please remember: Ascension will never ask for payment or to provide banking or financial information as part of the job application or hiring process, our legitimate email communications will always come from an @ascension.org email address; do not trust other domains, and an official offer will only be extended to candidates who have completed a job application through our authorized applicant tracking system.
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See All 19 Oncology Registered Nurse Jobs in Oklahoma
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Find JobsOncology Registered Nurse Jobs by City in Oklahoma
Where Oklahoma roles are concentrated, by current openings.
Oncology Registered Nurse Job Market in Oklahoma
A snapshot from current Oklahoma openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
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What Oklahoma Employers Look For
The qualifications that appear most often in oncology registered nurse jobs across Oklahoma.
- Active RN license issued or recognized by the Oklahoma Board of Nursing
- Oncology Nursing Certification (OCN) required or preferred by most employers
- Minimum one to two years of oncology or medical-surgical nursing experience
- Current BLS and ACLS certification from the American Heart Association
- Experience administering chemotherapy and managing oncology-related adverse effects
- Proficiency with electronic health record systems, commonly Epic or Cerner
Oncology Registered Nurse Jobs in Oklahoma: Frequently Asked Questions
How do you become a oncology registered nurse in Oklahoma?
You must first earn an Associate Degree in Nursing or a Bachelor of Science in Nursing, then pass the NCLEX-RN to obtain licensure through the Oklahoma Board of Nursing. Oklahoma participates in the Nurse Licensure Compact, so nurses licensed in other compact states may practice without a separate state license. Most employers then require at least one year of clinical experience before moving into an oncology-specific role, and many encourage pursuing the Oncology Nursing Certification once eligible.
How much do oncology registered nurses make in Oklahoma?
Oncology registered nurses in Oklahoma earn a median of about $82,920 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $60,530 for the lowest 10% to over $106,390 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire oncology registered nurses in Oklahoma?
Companies currently hiring oncology registered nurses in Oklahoma include OU Health, Mercy, and SSM Health, per current listings on Migrate Mate as of October 2026. Oklahoma's largest health systems, including those anchored in Oklahoma City and Tulsa, drive the majority of consistent oncology nursing openings across inpatient, outpatient, and infusion settings.
Which Oklahoma cities have the most oncology registered nurse jobs?
Oklahoma City and Tulsa have the most oncology registered nurse openings in Oklahoma. Oklahoma City leads because of its dense concentration of major health systems and the Stephenson Cancer Center, while Tulsa's demand is driven by Saint Francis Health System and Cancer Treatment Centers of America, drawing consistent oncology hiring across both inpatient and outpatient settings.
Are there remote oncology registered nurse jobs in Oklahoma?
Yes, but they're rare. Oncology nursing is a hands-on clinical role, and the large majority of positions require on-site patient care. About 0% of oncology registered nurse openings tied to Oklahoma are remote or hybrid as of October 2026, and those tend to be in telephonic triage, oncology case management, or utilization review rather than direct bedside care.
How can I get hired as a oncology registered nurse in Oklahoma with little or no experience?
The most realistic entry path is applying to a new graduate nurse residency program at a large Oklahoma health system such as OU Health or Integris Health, both of which run structured residencies that include oncology rotations. Candidates coming from medical-surgical, emergency, or critical care backgrounds are strong internal transfer candidates for oncology units. Earning a chemotherapy administration certificate through the Oncology Nursing Society before applying gives newer nurses a measurable credential that stands out to Oklahoma hiring managers.
Where can I find and apply to oncology registered nurse jobs in Oklahoma?
You can find and apply to oncology registered nurse jobs in Oklahoma on Migrate Mate, which lists current Oklahoma openings across health systems, cancer centers, and outpatient infusion clinics. Find roles that fit your experience and specialty area and apply directly to the employers posting them.
See All 19 Oncology Registered Nurse Jobs in Oklahoma
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