Project Leader Jobs in Maryland
Project Leader jobs in Maryland are concentrated in the Baltimore-Washington corridor, Annapolis, and the suburbs of Montgomery and Prince George's counties, where defense contracting, federal IT, and healthcare drive steady demand at every level from associate project lead to senior program lead. Employers like Northrop Grumman, Leidos, and Johns Hopkins Health System consistently post project leader roles with specialties in systems integration, clinical operations, and government program management. Competition is strong but openings are among the most active in the mid-Atlantic region. Scan the live roles below and apply to whichever ones fit.
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Be Part of One Team, One Purpose.
At Emmes Group, we’re shaping the future of clinical research—where human intelligence meets cutting-edge technology to drive meaningful advancements in healthcare. With over 47 years of scientific excellence, we’ve led groundbreaking research in cell and gene therapy, vaccines, infectious diseases, ophthalmology, rare diseases, and neuroscience.
Through our two business units—Emmes, a full-service CRO, and Veridix AI, our technology, data, and analytical solutions —we are modernizing clinical trials and accelerating the development of life-changing therapies.
We believe that every clinical breakthrough starts with people—people who are passionate, purpose-driven, and ready to make an impact. At Emmes Group, we bring People, Science, and Technology together to collaborate with our customers and deliver global health impact. Our culture is built on integrity, collaboration, and innovation, ensuring that every challenge is met with perseverance and accountability.
The Senior Project Leader (SPL) is critical to the successful conduct of government-sponsored clinical research projects, serving as the matrix leader of the core project team. The SPL is accountable for successful delivery of clients' statement of work activities within timeline and budget. The SPL develops and maintains a positive relationship with clients and other external stakeholders, oversees deliverable quality, mentors staff, and works collaboratively across departments to accomplish project goals. The SPL is responsible for the continuous monitoring, identification, escalation and mitigation of project risk.
- Serve as the lead for assigned government funded protocols and research initiatives.
- Serves as the client’s, investigators’ and other stakeholders’ primary point of contact for the project and/or assigned protocols.
- Develop, refine, and oversee deliverables such as study protocols, statistical analysis plans, clinical study reports, project plans, SOPs, etc.
- Ensure rigor, reproducibility, and adherence to good clinical practice (GCP), human subjects protections, and federal regulatory standards.
- Provide direction on study design, endpoints, methodology, and risk mitigation strategies.
- Oversee compliance with federal regulations including FDA, OHRP, NIH policy, HHS human subject protections, and other relevant agency requirements.
- Ensure IRB submissions, amendments, continuing reviews, and reporting obligations (AEs/SAEs, protocol deviations, unanticipated problems) are completed accurately and on time.
- Partner with quality assurance teams to support audits, monitoring visits, corrective action plans, and compliance documentation.
- Prepare and present updates, progress reports, technical summaries, and briefing materials.
- Provide subject matter expert input to stakeholders on emerging data, operational risks, and scientific considerations.
- Collaborate with cross functional departments—clinical operations, data management, biostatistics, regulatory, project management—to ensure integrated and high quality study execution.
- Guide operational teams in translating requirements into actionable project plans, timelines, and workstreams.
- Support the development and enhancement of SOPs, data standards, quality frameworks, and research governance structures.
- Oversee data quality, completeness, and scientific validity across all study activities.
- May lead the interpretation of results, author scientific manuscripts, and contribute to abstracts, posters, and presentations.
- Ensure timely and accurate submission of datasets, reports, publications, and regulatory packages to sponsors.
- Provide leadership and scientific guidance to clinical sites, subcontractors, consortia partners, and external collaborators.
- Participate in investigator meetings, scientific advisory boards, and expert panels.
- Foster collaborative relationships that advance the mission of assigned research programs.
- Ensure continuous protection of human subjects in accordance with federal policy, GCP, and corporate and institutional standards.
- Review safety data, oversee Data and Safety Monitoring Board (DSMB) interactions, and guide risk/benefit assessments.
- Escalates persistent issues and coordinates corrective action plans when needed.
- Selects and evaluates subcontractors and vendors in alignment with project needs and corporate standards.
- Negotiates scopes of work, deliverables, timelines, and pricing in collaboration with contract teams.
- Monitors vendor performance against contractual obligations and project milestones.
- Oversees development and approval of vendor Statements of Work (SOWs) and contract modifications.
- Represents the project in Corporate meetings (e.g., project reviews), with Executive leaders, as applicable.
- Uses key performance metrics to successfully execute the project scope.
- Mentors project staff and supports staff development; may be responsible for the development of new Project Leaders.
- Provide performance related feedback to department managers for project staff.
- Models Emmes culture of integrity, accountability, collaboration, innovation, and perseverance across internal and external teams.
- Promotes and implements relevant corporate initiatives as directed.
- Leads or contributes to the development of operational strategy, budget, and proposal content for new business opportunities, as assigned.
- Develops, maintains, and acquires approval of budgets and statement of work documents and subsequent modifications prior to distribution to clients, as well as approvals for invoices and subagreements.
- Performs other duties as assigned
- Complies with all policies and standards
- Bachelor's Degree Required or
- Master's Degree Preferred or
- PhD Preferred
- 12+ Years + Bachelor's with empirical knowledge of the key accountabilities/duties/responsibilities for the position with a typical tenure of at least 5 years project management experience in a research environment. Required or
- 9 years + Master's with empirical knowledge of the key accountabilities/duties/responsibilities for the position with a typical tenure of at least 5 years project management experience in a research environment. Preferred or
- 6 years + PhD with empirical knowledge of the key accountabilities/duties/responsibilities for the position with a typical tenure of at least 5 years project management experience in a research environment. Preferred
- Project Delivery Track Record: Demonstratable track record of successfully delivering complex/high-priority clinical trials or clinical research projects within the agreed time, quality, and budget. Experience in federally-funded research is preferred. High
- Clinical Research Knowledge: Demonstrated working knowledge of the principles of clinical research management and operations. High
- Problem-Solving: Demonstrated strong problem-solving and analytical skills, combined with sound business and ethical judgment. High
- Communication: Excellent verbal and written communication skills for client, team, and scientific interactions. High
- Leadership & Teamwork: Ability to work proactively and effectively, with creative problem-solving and collaboration skills. Highly motivated with the ability to work independently and as part of a multi-disciplinary team. Ability to supervise, mentor, and support lower-level project leaders and staff.
- Project Management: Strong cross-functional project management and time management skills.
- Therapeutic Expertise (Preferred): Broad understanding of a therapeutic area, clinical trial design, and/or process expertise to influence and execute project decisions.
If you’re looking for a career where your work advances global health and where scientific excellence meets real-world impact, join us and be part of something bigger. One Team, One Purpose.
CONNECT WITH US!
Find us on LinkedIn:/the-emmes-group/
Visit our website:https://www.theemmesgroup.com/
See All 7 Project Leader Jobs in Maryland
Find roles in Maryland that match your experience and apply in just a few clicks.
Find Project Leader JobsProject Leader Jobs by City in Maryland
Where Maryland roles are concentrated, by current openings.
Project Leader Job Market in Maryland
A snapshot from current Maryland openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Science & Research
What Maryland Employers Look For
The qualifications that appear most often in project leader jobs across Maryland.
- PMP certification or active enrollment in a PMI-recognized certification program
- Bachelor's degree in a relevant field such as engineering, IT, or business administration
- Three or more years of experience leading cross-functional project teams
- Proficiency with project management tools such as MS Project, Jira, or Smartsheet
- Experience working within federal government contracting environments or regulated industries
- Strong written and verbal communication skills for stakeholder and executive reporting
Project Leader Jobs in Maryland: Frequently Asked Questions
How do you become a project leader in Maryland?
Most project leader roles in Maryland require a bachelor's degree in engineering, IT, business, or a related field, combined with demonstrated team leadership experience. Maryland does not issue a state-specific license for project leaders, but the PMP credential from the Project Management Institute is widely expected by major employers in the state, particularly in defense contracting and healthcare. Earning the PMP or a related credential such as CAPM strengthens your candidacy significantly.
How much do project leaders make in Maryland?
Project leaders in Maryland earn a median of about $104,040 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $62,890 for the lowest 10% to over $167,040 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire project leaders in Maryland?
Maryland project leader roles are posted by The Emmes Company, MITRE, and AstraZeneca and others right now, based on current listings on Migrate Mate as of September 2026. Maryland's dense concentration of federal contractors and large health systems means openings appear across both the private sector and government-adjacent organizations throughout the state.
Which Maryland cities have the most project leader jobs?
Rockville, Aberdeen, and Baltimore have the most project leader openings in Maryland right now. Baltimore anchors demand through its healthcare and higher education institutions, while the Washington suburbs of Rockville, Bethesda, and Columbia are driven by federal contractors and technology firms with large campus presences in Montgomery and Howard counties.
Are there remote project leader jobs in Maryland?
Yes, and more than many roles, since project leadership work is largely coordination, planning, and communication rather than hands-on on-site labor. About 75% of project leader openings tied to Maryland are remote or hybrid as of September 2026, reflecting employer flexibility in this field. Program planning, stakeholder management, and reporting tasks are the functions most commonly performed remotely.
How can I get hired as a project leader in Maryland with little or no experience?
The most realistic entry path is moving laterally from a coordinator, analyst, or team lead role within a Maryland employer that values internal promotion. Large defense contractors such as Northrop Grumman and Leidos run formal rotational and associate programs that place early-career candidates in project support roles with a clear path to project leadership. Earning the CAPM credential from the Project Management Institute before applying gives candidates without a formal PM background a measurable edge in Maryland's competitive market.
Where can I find and apply to project leader jobs in Maryland?
You can find and apply to project leader jobs in Maryland on Migrate Mate, which lists current Maryland openings updated regularly. Search the roles available, identify the ones that match your experience and specialty, and apply directly to the employers posting them.
See All 7 Project Leader Jobs in Maryland
Find roles in Maryland that match your experience and apply in just a few clicks.
Find Project Leader Jobs