Senior Project Management Jobs in California
Senior Project Management jobs in California are among the most active in the country, with strong and sustained demand across technology, construction, aerospace, and healthcare sectors at every level from associate PM through vice president of project delivery. The largest concentrations of openings are in the San Francisco Bay Area, Los Angeles, and San Diego, where major employers such as Apple, Kaiser Permanente, and Bechtel maintain deep and ongoing hiring. The most sought-after specialties right now are enterprise IT transformation, large-scale infrastructure, and clinical operations program management. Find a role that fits below and apply directly.
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Job Description
About the role
The Senior Project Management Lead is a critical member of the Portfolio Management Office (PMO), supporting site-wide projects across the Thousand Oaks portfolio. This role ensures the timely and reliable supply of products to patients while delivering value to shareholders by driving operational excellence, enabling continuous improvement, and supporting site growth. The Senior Project Management Lead champions Takeda’s Project Management Methodology (PMM) and PMO processes, applying strong project leadership and management capabilities to oversee projects of varying scope, scale, and complexity. They will guide initiatives through the full project lifecycle, ensuring successful delivery on time, within scope, and within budget.
How you will contribute
PMO Leadership
- Ensure consistent use of Takeda’s Project Management Methodology (PMM) and support the site’s Project Portfolio Life Cycle Management (LCM) system.
- Monitor project and portfolio performance using PM tools, driving timely interventions and problem solving.
- Review phase-gate deliverables to ensure quality and readiness.
- Train and coach project teams, sponsors, and steering committees on PM best practices and tools.
- Improve project management processes by applying lessons learned and key performance indicators (KPIs).
- Help connect site strategy to project execution across the portfolio.
Project Management
- Lead cross-functional teams through all phases of the project lifecycle to deliver scope, schedule, budget, quality, and compliance targets.
- Manage core project planning and controls, including resources, costs, schedules, risk mitigation, communications, and documentation.
- Support project prioritization and contribute to strategic portfolio processes.
- Adjust plans proactively, escalate risks, and remove barriers to keep projects on track.
- Maintain clear stakeholder alignment and communicate status and escalations to sponsors and senior leadership.
- Operate independently while managing a diverse project workload.
- Perform additional duties as needed to support site goals.
Time Allocation
- 60% Project Management
- 10% PMO / Governance Support
- 10% Program Strategy Support
- 10% Training, Development & Site Activities
- 10% Flex / Other Duties
What you bring to Takeda
Education & Experience
- Bachelor’s degree in science, engineering, or related technical field preferred.
- 10+ years of project management experience leading complex cross-functional and technical projects (process, equipment, commissioning/validation, infrastructure, facilities, utilities, IT, digital).
- 5+ years of project management experience in the pharmaceutical or biotech (cGMP) industry.
- PMP® certification preferred; Lean/Six Sigma certification preferred.
Skills & Experience
- Strong multi-project management capability using formal PM methodologies.
- Experience leading projects in pharmaceutical/biotech regulated (cGMP) environments.
- Proficiency with key business and project management software (Microsoft Office, Project, Teams, PowerBI; Ariba/SAP/Veeva/TrackWise a plus).
- Excellent communication, facilitation, and stakeholder-management skills.
- Strong business acumen, attention to detail, and sound decision-making.
- Ability to influence, drive change, and lead cross-functional teams without direct authority.
- Strategic thinker with strong problem-solving skills and commitment to quality.
- Knowledge of regulatory standards (GxP, FDA, ISPE, GAMP, ASTM E2500).
Physical Requirements
- Mix of office work and on-floor presence within the facility.
- Occasional ladder climbing; ability to lift up to 25 lbs.
Working Environment
- Standard office environment with frequent cross-functional interaction.
- Fast-paced work with high expectations for timely execution.
- Occasional use of PPE or clean-room garments.
- May require after-hours, on-call, or weekend availability to support project needs.
What Takeda can offer you:
- Comprehensive Healthcare: Medical, Dental, and Vision
- Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
- Health & Wellness programs including onsite flu shots and health screenings
- Generous time off for vacation and the option to purchase additional vacation days
- Community Outreach Programs and company match of charitable contributions
- Family Planning Support
- Flexible Work Paths
- Tuition reimbursement
More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Empowering our people to shine:
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
USA - CA - Thousand Oaks - Rancho Conejo
U.S. Base Salary Range:
$111,800.00 - $175,670.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
Locations
USA - CA - Thousand Oaks - Rancho Conejo
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Job Exempt
Yes
Job Description
About the role
The Senior Project Management Lead is a critical member of the Portfolio Management Office (PMO), supporting site-wide projects across the Thousand Oaks portfolio. This role ensures the timely and reliable supply of products to patients while delivering value to shareholders by driving operational excellence, enabling continuous improvement, and supporting site growth. The Senior Project Management Lead champions Takeda’s Project Management Methodology (PMM) and PMO processes, applying strong project leadership and management capabilities to oversee projects of varying scope, scale, and complexity. They will guide initiatives through the full project lifecycle, ensuring successful delivery on time, within scope, and within budget.
How you will contribute
PMO Leadership
- Ensure consistent use of Takeda’s Project Management Methodology (PMM) and support the site’s Project Portfolio Life Cycle Management (LCM) system.
- Monitor project and portfolio performance using PM tools, driving timely interventions and problem solving.
- Review phase-gate deliverables to ensure quality and readiness.
- Train and coach project teams, sponsors, and steering committees on PM best practices and tools.
- Improve project management processes by applying lessons learned and key performance indicators (KPIs).
- Help connect site strategy to project execution across the portfolio.
Project Management
- Lead cross-functional teams through all phases of the project lifecycle to deliver scope, schedule, budget, quality, and compliance targets.
- Manage core project planning and controls, including resources, costs, schedules, risk mitigation, communications, and documentation.
- Support project prioritization and contribute to strategic portfolio processes.
- Adjust plans proactively, escalate risks, and remove barriers to keep projects on track.
- Maintain clear stakeholder alignment and communicate status and escalations to sponsors and senior leadership.
- Operate independently while managing a diverse project workload.
- Perform additional duties as needed to support site goals.
Time Allocation
- 60% Project Management
- 10% PMO / Governance Support
- 10% Program Strategy Support
- 10% Training, Development & Site Activities
- 10% Flex / Other Duties
What you bring to Takeda
Education & Experience
- Bachelor’s degree in science, engineering, or related technical field preferred.
- 10+ years of project management experience leading complex cross-functional and technical projects (process, equipment, commissioning/validation, infrastructure, facilities, utilities, IT, digital).
- 5+ years of project management experience in the pharmaceutical or biotech (cGMP) industry.
- PMP® certification preferred; Lean/Six Sigma certification preferred.
Skills & Experience
- Strong multi-project management capability using formal PM methodologies.
- Experience leading projects in pharmaceutical/biotech regulated (cGMP) environments.
- Proficiency with key business and project management software (Microsoft Office, Project, Teams, PowerBI; Ariba/SAP/Veeva/TrackWise a plus).
- Excellent communication, facilitation, and stakeholder-management skills.
- Strong business acumen, attention to detail, and sound decision-making.
- Ability to influence, drive change, and lead cross-functional teams without direct authority.
- Strategic thinker with strong problem-solving skills and commitment to quality.
- Knowledge of regulatory standards (GxP, FDA, ISPE, GAMP, ASTM E2500).
Physical Requirements
- Mix of office work and on-floor presence within the facility.
- Occasional ladder climbing; ability to lift up to 25 lbs.
Working Environment
- Standard office environment with frequent cross-functional interaction.
- Fast-paced work with high expectations for timely execution.
- Occasional use of PPE or clean-room garments.
- May require after-hours, on-call, or weekend availability to support project needs.
What Takeda can offer you:
- Comprehensive Healthcare: Medical, Dental, and Vision
- Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
- Health & Wellness programs including onsite flu shots and health screenings
- Generous time off for vacation and the option to purchase additional vacation days
- Community Outreach Programs and company match of charitable contributions
- Family Planning Support
- Flexible Work Paths
- Tuition reimbursement
More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Empowering our people to shine:
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
USA - CA - Thousand Oaks - Rancho Conejo
U.S. Base Salary Range:
$111,800.00 - $175,670.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and/or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
Locations
USA - CA - Thousand Oaks - Rancho Conejo
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Job Exempt
Yes
See All 2,887+ Senior Project Management Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
Find JobsSenior Project Management Jobs by City in California
Where California roles are concentrated, by current openings.
Senior Project Management Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring
- BKF Engineers112
- Amazon104
- NVIDIA71
- Apple56
- Google49
Top Industries Hiring
- Technology & Software819
- Consulting & Professional Services520
- Electronics & Hardware238
- Construction & Real Estate195
- Biotechnology & Pharmaceuticals142
What California Employers Look For
The qualifications that appear most often in senior project management jobs across California.
- PMP certification required or strongly preferred by most California enterprise employers
- Bachelor's degree in business, engineering, construction management, or a related field
- Seven or more years of project management experience with increasing responsibility
- Demonstrated experience managing cross-functional teams and budgets in complex environments
- Proficiency with enterprise project management tools such as Smartsheet, MS Project, or Jira
- Strong stakeholder communication and executive-level reporting skills required
Senior Project Management Jobs in California: Frequently Asked Questions
How do you become a senior project management in California?
The most direct path is earning a PMP certification through the Project Management Institute, which California employers treat as the standard professional credential for senior roles. California has no state-issued license specific to project management, so hiring decisions hinge on a combination of a bachelor's degree in a relevant field, several years of progressively responsible PM experience, and a recognized certification. Candidates in construction may also benefit from a CCM or LEED credential depending on the project type.
How much do senior project managements make in California?
Senior project managements in California earn a median of about $120,910 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $69,180 for the lowest 10% to over $188,560 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior project managements in California?
Employers hiring senior project managements in California right now include BKF Engineers, Amazon, and NVIDIA, based on current listings on Migrate Mate as of June 2026. California's mix of global technology headquarters, large health systems, and major defense and infrastructure contractors makes it one of the deepest markets in the country for experienced project management professionals.
Which California cities have the most senior project management jobs?
The cities with the most senior project management openings in California are San Francisco, Los Angeles, and San Jose. The Bay Area leads because of its concentration of enterprise technology and life sciences companies, Los Angeles draws volume from entertainment, aerospace, and healthcare, and San Diego's strong defense contracting and biotech sectors drive steady demand outside the two primary metros.
Are there remote senior project management jobs in California?
Yes, and more than most fields. About 24% of senior project management openings tied to California are remote or hybrid as of June 2026, reflecting how much of the role centers on coordination, documentation, and stakeholder communication rather than physical presence. The most fully remote opportunities tend to sit within software, fintech, and enterprise consulting firms, while construction and facilities roles almost always require on-site or hybrid arrangements.
How can I get hired as a senior project management in California with little or no experience?
The most realistic entry point is securing a coordinator or associate project manager role at a California technology company, large health system, or construction firm and building toward a PMP. Employers such as Kaiser Permanente, Salesforce, and major general contractors like Webcor regularly bring in candidates from adjacent roles including operations analyst, program coordinator, and business analyst. Completing a Google Project Management Certificate or an accredited PM certificate program, combined with a CAPM credential from PMI, measurably strengthens early applications in this market.
Where can I find and apply to senior project management jobs in California?
You can find and apply to senior project management jobs in California on Migrate Mate, which lists current openings from employers actively hiring in the state. Search the available roles, identify the ones that match your experience and target sector, and apply directly through each listing.
See All 2,887+ Senior Project Management Jobs in California
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