Staff Software Engineer Jobs in Ohio
Staff Software Engineer jobs in Ohio are in steady demand, with hiring concentrated in fintech, healthcare technology, defense and aerospace software, and enterprise SaaS across a range of seniority from mid-level engineer through principal. Columbus, Cleveland, and Cincinnati are the primary hiring metros, anchored by employers like Nationwide, Progressive, and NCR Atleos that maintain large engineering organizations in the state. Distributed systems, cloud platform engineering, and backend infrastructure are among the most sought-after specialties in Ohio listings. Find a role that fits below and apply directly.
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We are seeking a Senior Staff Software Engineer to help architect and build the data platform and backend services for our healthcare SaaS solutions. This is a hands-on technical leadership role requiring deep expertise in database and data architecture, cloud-native backend development, scalability, security, and healthcare interoperability.
The ideal candidate combines strong software engineering skills with the ability to design secure, high-performance data architectures for large-scale, multi-tenant applications handling sensitive healthcare data.
Key Responsibilities
- Architect and develop scalable backend services and data platforms for multi-tenant SaaS applications.
- Design and optimize relational and non-relational database architectures, data models, and storage strategies.
- Build scalable data ingestion, integration, and processing capabilities for large and complex healthcare datasets.
- Design cloud-native data architectures incorporating databases, data lakes/lakehouses, and distributed data platforms.
- Develop APIs and integration capabilities supporting healthcare interoperability, including HL7 and FHIR.
- Ensure appropriate architecture for security, encryption, access control, auditability, data governance, retention, and regulatory compliance.
- Design for high availability, disaster recovery, performance, and scalability.
- Provide technical leadership and architectural guidance while remaining hands-on with design and development.
- Collaborate with Software Engineering, Product, Security, Quality, and Regulatory teams.
Required Qualifications
- Bachelor’s or Master’s degree in Computer Science, Engineering, Information Systems, or related field.
- 10+ years of software engineering experience, including significant backend and data-platform development.
- Deep experience designing and optimizing relational databases such as PostgreSQL, SQL Server, or MySQL.
- Experience with NoSQL technologies such as MongoDB, Cosmos DB, or equivalent.
- Strong experience with cloud platforms (Azure, AWS, or GCP) and cloud-native architectures.
- Experience with modern data pipelines, ingestion frameworks, data lakes/lakehouses, and distributed data architectures.
- Strong understanding of multi-tenant SaaS architecture, APIs, scalability, security, and data governance.
- Experience designing systems that handle sensitive or regulated data.
Preferred Qualifications
- Healthcare software or regulated-industry experience.
- Experience with HL7, FHIR, EHR/EMR integration, or healthcare interoperability.
- Experience with Databricks, Azure Data Factory, Kafka, Spark, or similar technologies.
- Experience with containerized environments such as Docker and Kubernetes.
Compensation and Benefits
The salary range estimated for this position based in Indiana is $135,800.00–$203,750.00.This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
A choice of national medical and dental plans, and a national vision plan, including health incentive programs
Employee assistance and family support programs, including commuter benefits and tuition reimbursement
At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
See All 11 Staff Software Engineer Jobs in Ohio
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Find Staff Software Engineer JobsStaff Software Engineer Jobs by City in Ohio
Where Ohio roles are concentrated, by current openings.
Staff Software Engineer Job Market in Ohio
A snapshot from current Ohio openings, updated as new roles post.
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What Ohio Employers Look For
The qualifications that appear most often in staff software engineer jobs across Ohio.
- Bachelor's or master's degree in computer science, software engineering, or a related field
- Seven or more years of professional software engineering experience with demonstrated technical leadership
- Proficiency in one or more of Java, Python, Go, or C++ in production environments
- Experience designing and operating distributed systems or large-scale cloud-based architectures
- Track of mentoring engineers and driving code quality standards across an engineering team
- Familiarity with Agile development practices and CI/CD pipeline tooling in enterprise settings
Staff Software Engineer Jobs in Ohio: Frequently Asked Questions
How do you become a staff software engineer in Ohio?
Reaching staff-level in Ohio typically requires a bachelor's degree in computer science or a closely related field, followed by several years of progressive engineering experience. Ohio has no state-issued license for software engineers, so advancement comes through demonstrating technical depth and team leadership within a company. Strong candidates build expertise in a core stack, contribute to system design decisions, and take on mentorship responsibilities before being promoted or hired at the staff level.
How much do staff software engineers make in Ohio?
Staff software engineers in Ohio earn a median of about $114,090 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $77,790 for the lowest 10% to over $168,400 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire staff software engineers in Ohio?
Employers hiring staff software engineers in Ohio right now include Northrop Grumman, CVS Health, and Shield, based on current listings on Migrate Mate as of November 2026. Ohio's density of insurance, financial services, and healthcare technology firms means staff-level openings frequently appear at large corporate engineering organizations headquartered or with major operations in the state.
Which Ohio cities have the most staff software engineer jobs?
Ohio, Columbus, and Cincinnati account for the largest share of staff software engineer openings in Ohio. Columbus leads because of its concentration of insurance and fintech headquarters, Cleveland draws from a mix of healthcare technology and manufacturing software employers, and Cincinnati's presence of consumer goods and financial services firms generates consistent senior engineering demand in its suburban tech corridor.
Are there remote staff software engineer jobs in Ohio?
Yes, and more than most fields. About 33% of staff software engineer openings tied to Ohio are remote or hybrid as of November 2026, reflecting how broadly desk-based this role is. Platform engineering, backend infrastructure, and distributed systems work in particular are frequently offered on fully remote terms, while staff roles that require close collaboration with hardware, on-site labs, or regulated facilities tend to require in-office presence.
How can I get hired as a staff software engineer in Ohio with little or no experience?
The most realistic entry path is through associate or junior software engineer roles at large Ohio employers, where internal promotion tracks lead toward staff-level over time. Companies like Nationwide, Progressive, and Huntington Bancshares run structured new-grad and rotational engineering programs that place candidates without prior professional experience. Adjacent roles such as QA engineer, DevOps associate, or technical support engineer at Ohio firms also serve as practical entry points. Building a portfolio of personal or open-source projects and earning a cloud certification strengthens early applications considerably.
Where can I find and apply to staff software engineer jobs in Ohio?
You can find and apply to staff software engineer jobs in Ohio on Migrate Mate, which lists current Ohio openings from employers across the state. Find roles that fit your experience and apply directly to the ones that match.
See All 11 Staff Software Engineer Jobs in Ohio
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