ML Engineer Jobs in USA with Visa Sponsorship
There are 7,802+ ml engineer positions currently offering visa sponsorship in the United States. The most common visa types for these roles include H-1B, Green Card, TN. Top hiring companies include Apple, EY, & Deloitte, among others. Salaries for sponsored positions range from $164K – $1015K.
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Site Name: Cambridge 300 Technology Square, London The Stanley Building, South San Francisco 611 Gateway Blvd
Posted Date: Mar 2 2026
At GSK we see a world in which advanced applications of Machine Learning and AI will allow us to develop transformational medicines using the power of genetics, functional genomics and machine learning. AI will also play a role in how we diagnose and use medicines to enable everyone to do more feel better and live longer. It is an ambitious vision that will require the development of products at the cutting edge of Machine Learning and AI. The opportunities for machine learning extend to many other areas of our business, including medicine safety, manufacturing, and supply chain. To realize these opportunities, GSK has created a global Artificial Intelligence and Machine learning group (AI/ML), with locations in London, San Francisco, Boston, Philadelphia, and Heidelberg, to focus on the development and application of machine learning to problems of critical importance at GSK. We possess a world-leading data and computational environment (including specialist hardware) to enable large-scale, scientific experiments that exploit GSK’s unique access to data. By actively engaging with the machine learning community and publishing our research, code and models built on public data, the AI/ML group operates at the cutting-edge of machine learning research. To help us, we seek a passionate researcher who wishes to turn their talents to the application of causal machine learning to the healthcare sector. You will be working with multiple Research Engineers on building products to support multiple large-scale projects within AI/ML. In addition, the researcher will learn about the pharmaceutical industry and software engineering and translate their research into tools that aid discovery and development of transformational medicines and vaccines. You will have access to outstanding experts in biology, clinical and translational research, chemistry, (software) engineering, data science and machine learning; unrivalled data sources and GSK’s state-of-the-art laboratory and compute infrastructure to help you develop and validate your machine learning research.
As a Machine Learning Engineer focusing on applications in oncology, you will be expected to:
- Design and implement novel scientific approaches for biophysical modeling and foundation model-driven analysis of multi-modal clinical and genomic data for biomarker and target discovery to improve patient selection and enable next-generation assets.
- Design, develop, and implement analytical solutions using a variety of commercial and open-source tools (common tools include PyTorch and scikit-learn).
- Connect and collaborate with subject matter experts in biology, genomics, and medicine.
- Identify opportunities to apply the latest advancements in Machine Learning and Artificial Intelligence to build, test, and validate predictive models.
- Develop and embed automated and agentic processes for predictive model validation, deployment, and implementation.
- Deploy your algorithms to production to identify actionable insights from large databases.
Why you?
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:
- Master’s degree in computer science, applied math, statistics, physics, systems biology, computational biology, bioinformatics, or related field
- Experience in Python programming and knowledge in machine learning, statistics, and applied math.
- Familiarity with modern machine learning methods (generative models, representation learning)
- Experience in building deep learning models, preferably with exposure to biophysical modeling, functional genomics, molecular and cellular biology or to modeling dynamical systems
- Experience with at least one Deep Learning framework such as PyTorch
Preferred Qualifications:
If you have the following characteristics, they would be a plus:
- PhD in computer science, applied mathematics, statistics, physics, systems biology, computational biology, bioinformatics, or a related field.
- Experience in analyzing real-world and/or clinical data.
- Experience in incorporating agentic models into ML workflows
- Understanding of best practices in software engineering, including training and operating algorithms at scale, and production deployment of ML services.
- Knowledge of cancer biology and precision oncology.
- Excellent written and verbal communication skills.
- Ability to digest, synthesize, and implement innovative methods from scientific literature.
- Ability to solve complex problems using creative approaches, state-of-the-art tools, and best engineering practices.
- Ability to work autonomously and collaboratively as part of a team, both teaching and learning every day.
- High impact publications at venues such as NeurIPS, ICML, ICLR etc. would be a plus
- Publication in natural sciences would be a plus
If you are based in Cambridge, MA; Waltham, MA; Rockville, MD; or San Francisco, CA, the annual base salary for new hires in this position ranges $136,125 to $226,875. The US salary ranges take into account a number of factors including work location within the US market, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at HR.AmericasSC-CS@gsk.com where you can also request a call. Please note should your inquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receive.
GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.
Important notice to Employment businesses/ Agencies
GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/

How to Get Visa Sponsorship as a ML Engineer
Emphasize production ML skills, not just research or prototyping
Companies hiring ML engineers need people who can take models from experimentation to production - building data pipelines, implementing feature stores, deploying models with low-latency serving, and monitoring for drift. This production focus is what distinguishes ML engineers from research scientists. Demonstrating experience with MLOps tools like MLflow, Kubeflow, or SageMaker signals that you can deliver business value, not just build notebooks.
Target companies with mature ML infrastructure teams
Organizations like Google, Meta, Netflix, Spotify, and Uber have dedicated ML platform teams that build the infrastructure for deploying models at scale. These companies understand the specialized skills ML engineers bring and have streamlined sponsorship processes. Their scale of ML operations means ongoing hiring needs rather than one-off positions.
Leverage advanced degrees and published research as differentiators
A master's or Ph.D. provides both a competitive advantage in hiring and a stronger visa petition profile, and a U.S. advanced degree qualifies you for the additional H-1B lottery entry. Published papers at conferences like NeurIPS, ICML, or AAAI demonstrate expertise that immigration attorneys can cite as evidence of specialized knowledge.
Build expertise in a high-demand ML application area
Natural language processing, computer vision, recommendation systems, and generative AI are the areas with the strongest current demand. Specializing in one domain rather than being a generalist ML engineer makes you a more targeted hire for companies working on specific problems. Companies building LLM applications, autonomous driving systems, or medical image analysis have acute talent needs in their respective ML domains.
Consider AI-focused startups backed by significant venture funding
AI startups like Anthropic, OpenAI, Cohere, Scale AI, and Hugging Face have raised substantial venture capital and are hiring ML engineers aggressively. These companies offer competitive compensation, work on cutting-edge problems, and are accustomed to sponsoring international talent. Well-funded AI startups can often move faster on sponsorship than large enterprises because they have urgent hiring needs and streamlined decision-making.
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Get Access To All JobsFrequently Asked Questions
Is machine learning engineering a strong field for visa sponsorship?
Machine learning engineering is one of the strongest fields for visa sponsorship in the U.S. due to intense demand and a limited talent pool. Companies across technology, finance, healthcare, and autonomous vehicles are competing aggressively for ML engineers who can build and deploy production models. The specialized skills required - spanning mathematics, software engineering, and domain-specific modeling - make the specialty occupation case straightforward.
What qualifications strengthen an ML engineer's visa sponsorship case?
A master's or Ph.D. in computer science, machine learning, statistics, or a quantitative field is common among sponsored ML engineers, though a bachelor's degree with relevant experience can also qualify. Published research papers, conference presentations (NeurIPS, ICML, CVPR), and demonstrated production ML experience all strengthen the case. The combination of advanced mathematics and software engineering makes ML engineering one of the clearest specialty occupations for visa purposes.
Do ML engineers qualify for STEM OPT extensions?
Yes. Computer science, statistics, mathematics, and related fields that ML engineers typically study are STEM-designated. The 24-month STEM OPT extension gives you up to 36 months of work authorization after graduation, which is valuable given that ML engineer roles often require ramp-up time to understand a company's data infrastructure and model architecture. This extended period strengthens the employer's case for sponsorship.
Are ML engineer salaries sufficient to meet H-1B prevailing wage requirements?
ML engineer compensation is among the highest in the technology sector, with base salaries typically ranging from $140,000 to $220,000 at major tech companies and well-funded startups. Total compensation including equity can be significantly higher. These salary levels exceed H-1B prevailing wage thresholds by a substantial margin, making the wage requirement the least challenging aspect of an ML engineer's visa petition. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search tool.
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