Laboratory Manager Jobs in Pennsylvania
Laboratory Manager jobs in Pennsylvania are in strong demand, with concentrated openings across academic medical centers, pharmaceutical manufacturing, clinical diagnostics, and materials testing facilities at every level from entry-level lab coordinator to senior director. Philadelphia, Pittsburgh, and the Lehigh Valley are the largest hiring centers, anchored by well-established employers like Penn Medicine, UPMC, and Merck. The most in-demand specialties include clinical laboratory management, quality control oversight, and pharmaceutical compliance. Find a role that fits below and apply directly.
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Laboratory Manager II
The Kamil Lab in the University of Pittsburgh School of Medicine, Department of Microbiology and Molecular Genetics is recruiting an experienced Laboratory Manager II. The Kamil laboratory studies diverse aspects of the molecular interplay between viruses and their hosts, focusing primarily on human cytomegalovirus (aka HCMV or CMV). The laboratory is investigating how CMV exploits glycobiology to hide within the host and are also studying a new virion surface glycoprotein complex that plays roles in entry, which we recently discovered together with our collaborators. The lab is also interested in the fundamental cell biology underlying how CMV overtakes the host cell and manipulates the secretory pathway. The successful candidate will have extensive hands-on laboratory experience working with viruses at Biosafety Level 2. Specific skills should include: Propagation, purification and titration of virus stocks (plaque assay and/or TCID50), design and execution of infection time-course experiments, Mammalian cell culture and aseptic technique, including primary fibroblasts and epithelial cells, cryopreservation and maintenance of cell banks, standard molecular biology to include PCR, quantitative PCR (qPCR and RT-qPCR), isolation of DNA and RNA, gel electrophoresis, recombinant DNA and subcloning, site-directed mutagenesis, genetic techniques in bacteria, and experience generating recombinant viruses and/or engineered cell lines is highly desirable. The New Laboratory Manager II must also be able to independently design experiments, interpret data, develop and troubleshoot new methods and procedures with minimal oversight.
A bachelor's degree in microbiology or a related field is required. Those with experience in University of Pittsburgh systems and processes for purchasing and ordering, experience in a herpesvirus or DNA virus laboratory, and/or experience with BAC mutagenesis will be given preference. Qualified candidates should apply to requisition # 26005175 at Home | Talent Center: Careers at Pitt | University of Pittsburgh
Manages day-to-day laboratory operations while ensuring compliance with safety regulations and best practices. Works with, adapts, and installs scientific equipment in research laboratories. Develops and collaborates on routine projects and procedures. Manages inventory and equipment and performs budget functions.
The incumbent must be able to work closely with the faculty investigator to align day-to-day laboratory operations with long-term research goals while keeping near-term projects on schedule. The incumbent will also maintain inventory of reagents and supplies and handle routine purchasing of materials and equipment. Must be able to independently design and execute experiments with minimal oversight. Excellent record keeping and communication skills are needed.
The incumbent will spend most of the day moving about the laboratory. Will be required to lift light boxes and equipment.
The University of Pittsburgh is an equal opportunity employer / disability / veteran.
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Where Pennsylvania roles are concentrated, by current openings.
Laboratory Manager Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What Pennsylvania Employers Look For
The qualifications that appear most often in laboratory manager jobs across Pennsylvania.
- Bachelor's or master's degree in clinical laboratory science, biology, chemistry, or a related field
- Pennsylvania clinical laboratory director or supervisor certification where required by the Pennsylvania Department of Health
- Minimum three to five years of hands-on laboratory experience in a relevant discipline
- Demonstrated experience managing laboratory staff, budgets, and regulatory compliance programs
- Proficiency with laboratory information systems and quality management documentation
- Familiarity with CAP, CLIA, and Joint Commission accreditation standards as applied in Pennsylvania facilities
Laboratory Manager Jobs in Pennsylvania: Frequently Asked Questions
How do you become a laboratory manager in Pennsylvania?
Most laboratory manager roles in Pennsylvania require at least a bachelor's degree in clinical laboratory science, chemistry, biology, or a closely related field, with a master's degree preferred for hospital and health system roles. Pennsylvania clinical laboratories regulated under the Pennsylvania Department of Health may require supervisory or director certification depending on the laboratory's accreditation category. Candidates typically build several years of bench experience before moving into management, and holding or pursuing ASCP board certification strengthens applications considerably.
How much do laboratory managers make in Pennsylvania?
Laboratory managers in Pennsylvania earn a median of about $137,900 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $59,040 for the lowest 10% to over $312,510 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire laboratory managers in Pennsylvania?
Employers hiring laboratory managers in Pennsylvania right now include Penn State Health, Quest Diagnostics, and University of Pittsburgh, based on current listings on Migrate Mate as of August 2026. Pennsylvania's combination of large academic health systems, major pharmaceutical manufacturers in the Philadelphia suburbs, and industrial testing labs across the state creates consistent demand from a broad mix of employer types.
Which Pennsylvania cities have the most laboratory manager jobs?
Pittsburgh, Philadelphia, and Monaca have the most laboratory manager openings in Pennsylvania. Philadelphia and its surrounding suburbs drive the largest share of postings thanks to a dense cluster of academic medical centers, biotech firms, and pharmaceutical companies along the Route 202 corridor, while Pittsburgh's strength in hospital networks and Carnegie Mellon and Pitt-affiliated research institutions sustains steady demand in western Pennsylvania.
Are there remote laboratory manager jobs in Pennsylvania?
Yes, but they're rare. Laboratory managers typically oversee physical lab operations, staff, and equipment, so the role is inherently on-site. About 0% of laboratory manager openings tied to Pennsylvania are remote or hybrid as of August 2026, and those positions tend to involve quality systems coordination, regulatory documentation, or multi-site oversight rather than day-to-day bench supervision.
How can I get hired as a laboratory manager in Pennsylvania with little or no experience?
The most realistic entry path is moving into a lead technician or laboratory supervisor role first rather than applying directly to manager positions. Large Pennsylvania health systems like UPMC and Penn Medicine regularly hire new laboratory science graduates into bench roles with structured rotations that develop supervisory experience over time. Pursuing ASCP certification early, taking on quality control or safety coordinator duties in your current role, and targeting coordinator or assistant manager titles are the most effective steps toward a full management position.
Where can I find and apply to laboratory manager jobs in Pennsylvania?
You can find and apply to laboratory manager jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings updated regularly. Search the listings, find roles that match your background and target location, and apply directly to the ones that fit.
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