Operations Lead Jobs in Massachusetts
Operations Lead jobs in Massachusetts are concentrated in Boston, Cambridge, and Worcester, where companies like Raytheon Technologies, Mass General Brigham, and Liberty Mutual have long-standing operations teams. Demand is strongest in healthcare operations, defense and aerospace supply chain, and financial services process management, with openings at every level from first-time leads to senior operations managers overseeing multi-site teams. Massachusetts is among the most active markets in the Northeast for this role. Scan the live roles below and apply to whichever ones fit.
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About This Role
The Associate Director, Medical Strategy & Operations (S&O) Lead is a strategic operations leader within North America (NA) Medical Affairs and a core member of Rare Disease LT. The role drives strategy-to-execution integration, enterprise alignment, and coordination of governance processes and operating rhythm across Biogen North America.
The role partners closely with the Head of Rare Disease and Medical leadership team to help advance strategic integration across Medical leadership, Field teams, Medical Excellence, Operations, Global Medical, and Biogen North America stakeholders (including Commercial and Market Access). The role identifies opportunities and supports alignment between BNA enterprise priorities and NA Medical strategy and helps ensure clarity, coordinated execution, and effective flow of information and decisions across functions.
The S&O Lead supports the design and maintenance of governance, alignment, and operating structures that pull through strategy to enable coordinated execution across functions. This includes clarifying decision rights, ensuring appropriate ownership, and maintaining visibility of priorities and performance across the Therapeutic Area.
The role plays an important part in advancing the Medical S&O function’s strategic integrator model, helping connect strategy, governance, and execution across the Therapeutic Area while building toward broader enterprise leadership responsibilities.
What You’ll Do
Serve as a strategic thought partner to the Head of Rare Disease and Medical leadership team, supporting the identification of execution risks, operational challenges, and opportunities for alignment.
Drive and facilitate the integration of strategy-to-execution planning across planning cycles (AOP, ICP, long-range planning), helping translate strategic priorities into coordinated execution plans and measurable milestones.
Drive and coordinate the operating rhythm for the Rare Disease Medical team, including milestone tracking, governance forums, KPI integration, and preparation for leadership reviews.
Partner with cross-functional stakeholders to ensure Medical priorities and activities are appropriately represented within the broader BNA operating cadence.
Facilitate effective information flow and strategic communication across Medical leadership, enterprise partners, and key governance forums.
Develop and support preparation of executive materials and strategic narratives that communicate Medical priorities, progress, risks, and key decisions for leadership audiences.
Partner with Finance and medical Rare Disease LT to lead budget planning, monitoring, and performance tracking for the Therapeutic Area.
Help identify execution risks, structural barriers, and cross-functional dependencies, facilitating alignment and resolution with appropriate stakeholders.
Support coordination between NA Medical and Global Medical teams to ensure alignment across strategic initiatives and key workstreams.
Contribute to continuous improvement initiatives that enhance operating clarity, governance effectiveness, and enterprise collaboration.
Promote a culture of accountability, transparency, and cross-functional partnership within the Therapeutic Area and broader Medical organization.
Who You Are
You are a strategic leader who operates effectively at the intersection of strategy, governance, and execution in a complex matrixed organization. You are comfortable navigating ambiguity, influencing stakeholders without formal authority, and helping drive alignment across cross-functional teams. You combine strong business acumen, financial discipline, and operational rigor with clear communication and structured problem-solving. You balance enterprise perspective with Medical integrity and scientific rigor.
Required Skills
BA/BS required; advanced degree (MBA, MS, PhD) preferred.
7+ years of pharmaceutical/biotech industry experience required.
7+ years of relevant experience in biopharma strategy, operations, consulting, Medical Affairs, or related enterprise-facing roles required.
Experience supporting cross-functional planning, governance processes, or program management required.
Demonstrated business and financial acumen.
Strong organizational and problem-solving skills.
Strong communication and presentation skills.
Ability to influence across a matrixed organization without direct authority.
Strong command of core business tools (Excel, PowerPoint, etc.).
Preferred Skills
Experience working in alliance or cross-enterprise environments.
Global Medical or affiliate experience.
Experience in financial planning.
Change management experience.
Job Level: Management
Additional Information
Base salary offered is determined through an analytical approach utilizing a combination of factors including, but not limited to, relevant skills & experience, job location, and internal equity.
Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
In addition to compensation, Biogen offers a full and highly competitive range of benefits designed to support our employees’ and their families physical, financial, emotional, and social well-being ; including, but not limited to:
- Medical, Dental, Vision, & Life insurances
- Fitness & Wellness programs including a fitness reimbursement
- Short- and Long-Term Disability insurance
- A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
- Up to 12 company paid holidays + 3 paid days off for Personal Significance
- 80 hours of sick time per calendar year
- Paid Maternity and Parental Leave benefit
- 401(k) program participation with company matched contributions
- Employee stock purchase plan
- Tuition reimbursement of up to $10,000 per calendar year Employee Resource Groups participation
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about Biogen.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
See All 52 Operations Lead Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Operations Lead JobsOperations Lead Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Operations Lead Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Technology & Software
- Science & Research
- Biotechnology & Pharmaceuticals
- Retail
- Education
What Massachusetts Employers Look For
The qualifications that appear most often in operations lead jobs across Massachusetts.
- 3 to 5 years of operations experience in a relevant Massachusetts industry sector
- Demonstrated ability to manage cross-functional teams and daily workflow coordination
- Proficiency with ERP or operations management platforms such as SAP or Oracle
- Bachelor's degree in business administration, operations management, or a related field
- Experience applying Lean, Six Sigma, or continuous improvement methodologies
- Strong data analysis skills with ability to report on KPIs and operational metrics
Operations Lead Jobs in Massachusetts: Frequently Asked Questions
How do you become a operations lead in Massachusetts?
Most operations lead roles in Massachusetts require a bachelor's degree in business, operations management, supply chain, or a related field, combined with several years of relevant industry experience. There is no state-issued license required for the role itself, but candidates targeting healthcare operations may benefit from credentials like a Lean Six Sigma certification or project management certification recognized by Massachusetts employers. Building experience in coordinator or analyst roles at Massachusetts hospitals, defense contractors, or financial firms is the most direct path.
Which companies hire operations leads in Massachusetts?
Massachusetts operations lead roles are posted by lululemon, Takeda Pharmaceuticals, and CARVANA and others right now, based on current listings on Migrate Mate as of August 2026. Massachusetts's concentration of healthcare systems, defense contractors, and financial services firms means hiring tends to be consistent across the year rather than seasonal.
Which Massachusetts cities have the most operations lead jobs?
Boston, Somerville, and Cambridge have the most operations lead openings in Massachusetts. Boston drives the largest share of postings given its dense healthcare, finance, and technology sectors, while Worcester and Cambridge generate steady demand through their academic medical centers, biotech campuses, and university-affiliated research operations pulling roles into the surrounding metro areas.
Are there remote operations lead jobs in Massachusetts?
Yes, but they're a minority of openings, since operations leads are frequently expected to be present on-site to oversee teams and processes directly. About 62% of operations lead openings tied to Massachusetts are remote or hybrid as of August 2026, with hybrid arrangements more common than fully remote. The parts of the role most likely to allow remote work are reporting, planning, and vendor coordination tasks rather than floor-level or facility oversight responsibilities.
How can I get hired as a operations lead in Massachusetts with little or no experience?
The most realistic entry path is moving into an operations coordinator or operations associate role at a large Massachusetts employer and building toward a lead position from within. Mass General Brigham, Raytheon Technologies, and major financial firms in Boston regularly recruit for operations support roles that serve as feeders into lead positions. A Lean Six Sigma yellow or green belt certification, even without experience, signals process thinking that hiring managers value. Lateral moves from project coordinator, logistics, or administrative management roles are also common stepping stones.
Where can I find and apply to operations lead jobs in Massachusetts?
You can find and apply to operations lead jobs in Massachusetts on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the listings to find roles that match your experience and location, then apply directly to the ones that fit.
See All 52 Operations Lead Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Operations Lead Jobs