Principal Jobs in Wisconsin
Principal jobs in Wisconsin are in steady demand, with the strongest concentration in K-12 public school districts, charter networks, and private and parochial schools. Milwaukee, Madison, and Green Bay are the largest hiring metros, where districts such as Milwaukee Public Schools, Madison Metropolitan School District, and Green Bay Area Public School District maintain ongoing principal needs across elementary, middle, and high school buildings. The most sought-after specialties include instructional leadership, special education administration, and turnaround school leadership. Find a role that fits below and apply directly.
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Principal Scientist – Process Development, Downstream
Catalent is seeking a Principal Scientist, Process Development – Downstream to support the early phase and technical transfer processes for biologics manufacturing.
This is a highly visible, client-facing Process Development role supporting the advancement of biologics programs across a diverse portfolio of mAbs, multispecifics, and recombinant proteins. While approximately 25% hands-on laboratory based, the majority of the role focuses on technical leadership, program management, and guiding teams through downstream process development activities including chromatography, UF/DF, filtration, viral clearance, and cell removal processes.
About Catalent Madison
Catalent's Madison, Wisconsin facility is a state-of-the-art biologics development and manufacturing site supporting customers from research through early- and mid-stage clinical production. Located at 726 Heartland Trail, the 102,700-square-foot GMP facility specializes in mammalian cell line engineering, drug substance manufacturing, and biopharmaceutical process development.
The site is home to Catalent's proprietary GPEx® and GPEx® Lightning technologies, enabling the generation of high-producing mammalian cell lines for biologic therapies. With production capabilities ranging from 50L to 4,000L and a recent $45 million expansion, the Madison campus continues to play a critical role in Catalent's global biologics network while supporting Wisconsin's growing life sciences industry.
Location: 100% Onsite at our facility in Madison, Wisconsin
Shift: Monday – Friday, First Shift
Key Responsibilities
Technical Leadership & Scientific Strategy: Serve as the scientific lead for downstream process development programs supporting monoclonal antibodies (mAbs), multispecific antibodies, and recombinant protein therapeutics. Provide strategic direction, scientific consultation, and technical oversight across multiple client programs.
Process Development Oversight: Guide the design, development, optimization, and characterization of downstream processes, including chromatography, ultrafiltration/diafiltration (UF/DF), viral filtration, clarification, and cell removal methodologies to enable successful clinical and commercial manufacturing.
Client Partnership & Program Management: Act as the primary technical contact for client development projects, leading meetings, communicating project status, providing scientific rationale, and ensuring alignment between technical execution and program objectives.
Technology Transfer & Commercial Readiness: Lead technology transfer activities, scale-up strategies, process characterization studies, and viral clearance programs to support progression from development through cGMP manufacturing.
Cross-Functional Leadership: Collaborate with Process Development, MS&T, Manufacturing, Quality, and Analytical teams to drive project execution, troubleshoot technical challenges, and ensure successful project delivery.
Technical Documentation & Review: Author, review, and approve technical documents including protocols, reports, SOPs, batch records, and client-facing deliverables while ensuring compliance with Good Documentation Practices (GDP) and regulatory expectations.
Innovation & Continuous Improvement: Evaluate emerging technologies, identify opportunities for process enhancement, and contribute to the advancement of scientific capabilities, service offerings, and best practices within the organization.
Mentorship & Scientific Development: Mentor scientists and technical staff, providing coaching, guidance, and knowledge-sharing to support team growth and development.
Other responsibilities as needed.
Required Qualifications
Ph.D. in Biotechnology, Biochemical Engineering, Chemical Engineering, Biology, or a related scientific discipline with a minimum of 8 years of relevant industry experience; master's degree with a minimum of 12 years of experience; or bachelor's degree with a minimum of 15 years of experience.
Demonstrated expertise in development and commercialization of mAbs, multispecifics, recombinant proteins, or other complex biologic therapeutics.
Strong expertise in chromatography, filtration, UF/DF, viral filtration, and cell removal technologies.
Proven experience leading technical programs and serving as a client-facing scientific representative.
Demonstrated knowledge of cGMP environments, technology transfer, process characterization, and scale-up.
Excellent scientific communication, problem-solving, and project management skills.
Preferred Qualifications
Experience in a biopharmaceutical, biotechnology, or CDMO environment.
Track record of leading cross-functional teams and mentoring scientific staff.
Experience supporting multiple client programs simultaneously.
Expertise in viral clearance studies, late-stage process development, and commercial manufacturing readiness.
Strong business acumen and ability to build client relationships.
Why you should join Catalent
Opportunity to play a key role in driving growth within a global CDMO leader.
Competitive compensation package, including incentive opportunity.
Day-one medical, dental, and vision coverage.
401(k) with company match.
Tuition reimbursement and professional development opportunities.
Generous paid time off and holiday schedule (152 hours + 8 holidays)
Collaborative, mission-driven culture focused on improving patient outcomes worldwide.
Catalent offers rewarding opportunities to further your career! Join the global drug development and delivery leader and help us bring over 7,000 life-saving and life-enhancing products to patients around the world. Catalent is an exciting and growing international company where employees work directly with pharma, biopharma and consumer health companies of all sizes to advance new medicines from early development to clinical trials and to the market. Catalent produces more than 70 billion doses per year, and each one will be used by someone who is counting on us. Join us in making a difference.
personal initiative. dynamic pace. meaningful work.
Visit Catalent Careers to explore career opportunities.
Catalent is an Equal Opportunity Employer, including disability and veterans.
If you require reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email, and confirming your request for an accommodation and include the job number, title and location to DisabilityAccommodations@catalent.com. This option is reserved for individuals who require accommodation due to a disability. Information received will be processed by a U.S. Catalent employee and then routed to a local recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process.
Notice to Agency and Search Firm Representatives: Catalent Pharma Solutions (Catalent) is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Catalent employee by a third party agency and/or search firm without a valid written & signed search agreement, will become the sole property of Catalent. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral. Thank you.
Important Security Notice to U.S. Job Seekers:
Catalent NEVER asks candidates to provide any type of payment, bank details, photocopies of identification, social security number or other highly sensitive personal information during the offer process, and we NEVER do so via email or social media. If you receive any such request, DO NOT respond— it is a fraudulent request. Please forward such requests to spam@catalent.com for us to investigate with local authorities.
California Job Seekers can find our California Job Applicant Notice HERE.
Volunteer Work Disclosure: Applicants for employment in Massachusetts may include in their employment history any verified work performed on a volunteer basis.
Massachusetts Lie Detector Test Notice: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law may be subject to criminal penalties and civil liability. Consistent with Massachusetts law, Catalent does not require or administer lie detector tests as a condition of employment or continued employment.
Principal Scientist – Process Development, Downstream
Catalent is seeking a Principal Scientist, Process Development – Downstream to support the early phase and technical transfer processes for biologics manufacturing.
This is a highly visible, client-facing Process Development role supporting the advancement of biologics programs across a diverse portfolio of mAbs, multispecifics, and recombinant proteins. While approximately 25% hands-on laboratory based, the majority of the role focuses on technical leadership, program management, and guiding teams through downstream process development activities including chromatography, UF/DF, filtration, viral clearance, and cell removal processes.
About Catalent Madison
Catalent's Madison, Wisconsin facility is a state-of-the-art biologics development and manufacturing site supporting customers from research through early- and mid-stage clinical production. Located at 726 Heartland Trail, the 102,700-square-foot GMP facility specializes in mammalian cell line engineering, drug substance manufacturing, and biopharmaceutical process development.
The site is home to Catalent's proprietary GPEx® and GPEx® Lightning technologies, enabling the generation of high-producing mammalian cell lines for biologic therapies. With production capabilities ranging from 50L to 4,000L and a recent $45 million expansion, the Madison campus continues to play a critical role in Catalent's global biologics network while supporting Wisconsin's growing life sciences industry.
Location: 100% Onsite at our facility in Madison, Wisconsin
Shift: Monday – Friday, First Shift
Key Responsibilities
Technical Leadership & Scientific Strategy: Serve as the scientific lead for downstream process development programs supporting monoclonal antibodies (mAbs), multispecific antibodies, and recombinant protein therapeutics. Provide strategic direction, scientific consultation, and technical oversight across multiple client programs.
Process Development Oversight: Guide the design, development, optimization, and characterization of downstream processes, including chromatography, ultrafiltration/diafiltration (UF/DF), viral filtration, clarification, and cell removal methodologies to enable successful clinical and commercial manufacturing.
Client Partnership & Program Management: Act as the primary technical contact for client development projects, leading meetings, communicating project status, providing scientific rationale, and ensuring alignment between technical execution and program objectives.
Technology Transfer & Commercial Readiness: Lead technology transfer activities, scale-up strategies, process characterization studies, and viral clearance programs to support progression from development through cGMP manufacturing.
Cross-Functional Leadership: Collaborate with Process Development, MS&T, Manufacturing, Quality, and Analytical teams to drive project execution, troubleshoot technical challenges, and ensure successful project delivery.
Technical Documentation & Review: Author, review, and approve technical documents including protocols, reports, SOPs, batch records, and client-facing deliverables while ensuring compliance with Good Documentation Practices (GDP) and regulatory expectations.
Innovation & Continuous Improvement: Evaluate emerging technologies, identify opportunities for process enhancement, and contribute to the advancement of scientific capabilities, service offerings, and best practices within the organization.
Mentorship & Scientific Development: Mentor scientists and technical staff, providing coaching, guidance, and knowledge-sharing to support team growth and development.
Other responsibilities as needed.
Required Qualifications
Ph.D. in Biotechnology, Biochemical Engineering, Chemical Engineering, Biology, or a related scientific discipline with a minimum of 8 years of relevant industry experience; master's degree with a minimum of 12 years of experience; or bachelor's degree with a minimum of 15 years of experience.
Demonstrated expertise in development and commercialization of mAbs, multispecifics, recombinant proteins, or other complex biologic therapeutics.
Strong expertise in chromatography, filtration, UF/DF, viral filtration, and cell removal technologies.
Proven experience leading technical programs and serving as a client-facing scientific representative.
Demonstrated knowledge of cGMP environments, technology transfer, process characterization, and scale-up.
Excellent scientific communication, problem-solving, and project management skills.
Preferred Qualifications
Experience in a biopharmaceutical, biotechnology, or CDMO environment.
Track record of leading cross-functional teams and mentoring scientific staff.
Experience supporting multiple client programs simultaneously.
Expertise in viral clearance studies, late-stage process development, and commercial manufacturing readiness.
Strong business acumen and ability to build client relationships.
Why you should join Catalent
Opportunity to play a key role in driving growth within a global CDMO leader.
Competitive compensation package, including incentive opportunity.
Day-one medical, dental, and vision coverage.
401(k) with company match.
Tuition reimbursement and professional development opportunities.
Generous paid time off and holiday schedule (152 hours + 8 holidays)
Collaborative, mission-driven culture focused on improving patient outcomes worldwide.
Catalent offers rewarding opportunities to further your career! Join the global drug development and delivery leader and help us bring over 7,000 life-saving and life-enhancing products to patients around the world. Catalent is an exciting and growing international company where employees work directly with pharma, biopharma and consumer health companies of all sizes to advance new medicines from early development to clinical trials and to the market. Catalent produces more than 70 billion doses per year, and each one will be used by someone who is counting on us. Join us in making a difference.
personal initiative. dynamic pace. meaningful work.
Visit Catalent Careers to explore career opportunities.
Catalent is an Equal Opportunity Employer, including disability and veterans.
If you require reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email, and confirming your request for an accommodation and include the job number, title and location to DisabilityAccommodations@catalent.com. This option is reserved for individuals who require accommodation due to a disability. Information received will be processed by a U.S. Catalent employee and then routed to a local recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process.
Notice to Agency and Search Firm Representatives: Catalent Pharma Solutions (Catalent) is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Catalent employee by a third party agency and/or search firm without a valid written & signed search agreement, will become the sole property of Catalent. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral. Thank you.
Important Security Notice to U.S. Job Seekers:
Catalent NEVER asks candidates to provide any type of payment, bank details, photocopies of identification, social security number or other highly sensitive personal information during the offer process, and we NEVER do so via email or social media. If you receive any such request, DO NOT respond— it is a fraudulent request. Please forward such requests to spam@catalent.com for us to investigate with local authorities.
California Job Seekers can find our California Job Applicant Notice HERE.
Volunteer Work Disclosure: Applicants for employment in Massachusetts may include in their employment history any verified work performed on a volunteer basis.
Massachusetts Lie Detector Test Notice: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law may be subject to criminal penalties and civil liability. Consistent with Massachusetts law, Catalent does not require or administer lie detector tests as a condition of employment or continued employment.
See All 28 Principal Jobs in Wisconsin
Find roles in Wisconsin that match your experience and apply in just a few clicks.
Find Principal JobsPrincipal Jobs by City in Wisconsin
Where Wisconsin roles are concentrated, by current openings.
Principal Job Market in Wisconsin
A snapshot from current Wisconsin openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Technology & Software
What Wisconsin Employers Look For
The qualifications that appear most often in principal jobs across Wisconsin.
- Hold a valid Wisconsin administrator license with a principal endorsement from DPI
- Possess a master's degree in educational leadership, administration, or a related field
- Demonstrate at least three years of licensed teaching experience in an accredited school
- Show experience leading curriculum development, instructional coaching, or school improvement planning
- Demonstrate proficiency with Wisconsin student data systems and state assessment frameworks
- Exhibit strong skills in staff evaluation, professional development, and community engagement
Principal Jobs in Wisconsin: Frequently Asked Questions
How do you become a principal in Wisconsin?
To become a principal in Wisconsin, you must hold a Wisconsin administrator license with a principal endorsement issued by the Wisconsin Department of Public Instruction. This requires completing an approved educational leadership graduate program, holding a valid teaching license, and meeting the experience requirements set by DPI. Most candidates earn a master's degree before applying, and some districts also require passing the School Leaders Licensure Assessment.
Which companies hire principals in Wisconsin?
Wisconsin principal roles are posted by Techtronic Industries Co., Oracle, and Eli Lilly and others right now, based on current listings on Migrate Mate as of September 2026. Wisconsin's mix of large urban districts, suburban K-12 systems, and growing charter and private school networks means principal openings appear across the state throughout the year.
Which Wisconsin cities have the most principal jobs?
Brookfield, Madison, and Milwaukee have the most principal openings in Wisconsin. Milwaukee leads because of the scale of Milwaukee Public Schools and the density of charter and parochial schools in the metro, while Madison's demand is driven by the Madison Metropolitan School District and nearby suburban districts in Dane County, and Green Bay reflects the growth of Northeast Wisconsin's K-12 enrollment.
Are there remote principal jobs in Wisconsin?
Yes, but they're rare. About 60% of principal openings tied to Wisconsin are remote or hybrid as of September 2026, reflecting that most principal roles require daily on-site leadership of staff, students, and building operations. The portions of the role most likely to be performed off-site include administrative tasks, reporting, and some district-level coordinator or virtual school director positions.
How can I get hired as a principal in Wisconsin with little or no experience?
The most realistic entry path is moving into an assistant principal role, which is how most first-time principals in Wisconsin build their administrative record. Large districts like Milwaukee Public Schools and Madison Metropolitan School District regularly hire assistant principals from their own teaching ranks. Candidates strengthen their standing by completing a DPI-approved leadership preparation program, earning the principal endorsement early, and taking on department head, instructional coach, or curriculum coordinator roles that demonstrate school-level leadership before applying.
Where can I find and apply to principal jobs in Wisconsin?
You can find and apply to principal jobs in Wisconsin on Migrate Mate, which lists current Wisconsin openings across school districts, charter networks, and private schools. Find roles that fit your experience and location and apply directly to the ones that interest you.
See All 28 Principal Jobs in Wisconsin
Find roles in Wisconsin that match your experience and apply in just a few clicks.
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