Program Assistant Jobs in South Carolina

Program Assistant jobs in South Carolina are concentrated in Columbia, Charleston, and Greenville, where state government agencies, major health systems, and research universities drive consistent demand for program support roles in administration, public health, and higher education. Employers such as the Medical University of South Carolina, Prisma Health, and the South Carolina Department of Health and Environmental Control maintain a steady need for program assistants at both entry and mid-career levels. Demand is especially strong in grant administration, community health outreach, and government program coordination. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles20
Top employerState of South Carolina
Top cityRichland County, SC
Cities hiring8
Work type100% On-site
Top industryEducation

Showing 5 of 20+ Program Assistant jobs

University of South Carolina
Physician Assistant Program-Principal Faculty
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University of South Carolina
Added 2d ago
Physician Assistant Program-Principal Faculty
University of South Carolina
Richland, South Carolina
Nursing
Healthcare Administration
Teaching & Instruction
$100k - $106k/yr
On-Site
Doctorate
5,001-10,000

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State of South Carolina
Customer Service Representitve (Program Assistant)-61007783
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State of South Carolina
Added 5d ago
Customer Service Representitve (Program Assistant)-61007783
State of South Carolina
Orangeburg County, SC
Customer Service
Customer Service & Support
Customer Support
$38k - $39k/yr
On-Site
High school diploma or GED
10,000+

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State of South Carolina
Customer Service Representitve (Program Assistant)-61007576
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State of South Carolina
Added 5d ago
Customer Service Representitve (Program Assistant)-61007576
State of South Carolina
York County, SC
Accounting
Customer Service
Customer Support
$38k - $39k/yr
On-Site
High school diploma or GED
10,000+

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University of South Carolina
Program Assistant
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University of South Carolina
Added 5d ago
Program Assistant
University of South Carolina
Richland, South Carolina
Business Development
Marketing
Sales
Bachelor's degree
5,001-10,000

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Active Day
Aides - Program Assistant
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Active Day
Added 6d ago
Aides - Program Assistant
Active Day
Greer, South Carolina
Customer Service
Customer Support
High school diploma or GED
1,001-5,000

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See All 20 Program Assistant Jobs in South Carolina

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Program Assistant Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
2 jobs
Richland
2 jobs
North Charleston
2 jobs
Cayce
1 job
Greer
1 job
Indian Land
1 job
Spartanburg
1 job
Myrtle Beach
1 job

Program Assistant Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

State of South Carolina
State of South Carolina8 open roles
Active Day
Active Day3 open roles
University of South Carolina
University of South Carolina2 open roles

Top Industries Hiring

  • Education

What South Carolina Employers Look For

The qualifications that appear most often in program assistant jobs across South Carolina.

  • Associate or bachelor's degree in a relevant field from an accredited institution
  • Experience coordinating programs or providing administrative support in an office setting
  • Proficiency with Microsoft Office Suite including Word, Excel, and Outlook
  • Strong written and verbal communication skills for internal and external stakeholders
  • Ability to manage multiple deadlines and prioritize tasks in a fast-paced environment
  • Familiarity with data entry, recordkeeping, and reporting procedures

Program Assistant Jobs in South Carolina: Frequently Asked Questions

How do you become a program assistant in South Carolina?

Most program assistant roles in South Carolina require at minimum an associate degree, though many employers prefer a bachelor's degree in public administration, health sciences, business, or a related field. There is no state-issued license specific to the program assistant title, but roles within state agencies often require a background check and completion of South Carolina state onboarding requirements. Starting in agency support, nonprofit administration, or a university department coordinator role is the most common entry path in this state.

Which companies hire program assistants in South Carolina?

Companies currently hiring program assistants in South Carolina include State of South Carolina, Active Day, and University of South Carolina, per current listings on Migrate Mate as of October 2026. South Carolina's concentration of state government agencies, academic medical centers, and federally funded research institutions makes it one of the more active markets for ongoing program assistant openings.

Which South Carolina cities have the most program assistant jobs?

Richland County, York County, and Columbia have the most program assistant openings in South Carolina. Columbia leads because it is the state capital and home to the University of South Carolina and numerous state agencies, while Charleston's growth in healthcare and higher education through MUSC drives demand there, and Greenville's expanding corporate and healthcare base supports steady openings in the Upstate region.

Are there remote program assistant jobs in South Carolina?

Yes, but they are less common than in purely desk-based fields, since many program assistant roles involve in-person coordination, filing, and stakeholder meetings. About 0% of program assistant openings tied to South Carolina are remote or hybrid as of October 2026, with the most flexibility found in grant administration and data-focused program support roles rather than direct service coordination positions.

How can I get hired as a program assistant in South Carolina with little or no experience?

The most realistic entry path is applying to administrative coordinator or program support associate postings at South Carolina state agencies, the University of South Carolina system, or Prisma Health, all of which regularly post roles open to recent graduates. A completed internship with a South Carolina nonprofit or government office, combined with demonstrated experience in scheduling and data entry, gives candidates a strong edge. Pursuing a certificate in project management or public administration strengthens applications for competitive agency roles.

Where can I find and apply to program assistant jobs in South Carolina?

You can find and apply to program assistant jobs in South Carolina on Migrate Mate, which lists current South Carolina openings updated regularly. Search the listings to find roles that match your experience and location, then apply directly to the ones that fit. No profile creation is required to view or apply to openings.

See All 20 Program Assistant Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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