Technical Program Manager Jobs in Missouri
Technical Program Manager jobs in Missouri are open across O'Fallon, Kansas City, and St. Louis and other Missouri metros, with employers like Mastercard, Affirm, and Clayco hiring at every experience level. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 44+ Technical Program Manager jobs











Our Purpose
Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential.
Title and Summary
Principal, Technical Program Manager
Who is Mastercard?
Mastercard is a global technology company in the payments industry. Our mission is to connect and power an inclusive, digital economy that benefits everyone, everywhere by making transactions safe, simple, smart, and accessible. Using secure data and networks, partnerships and passion, our innovations and solutions help individuals, financial institutions, governments, and businesses realize their greatest potential.
Our decency quotient, or DQ, drives our culture and everything we do inside and outside of our company. With connections across more than 210 countries and territories, we are building a sustainable world that unlocks priceless possibilities for all.
Overview
The Technology Operations & Delivery R&D team is looking for a Principle TPM to drive our customer experience strategy forward by consistently innovating and problem-solving. The ideal candidate will oversee complex projects in a dynamic, fast-paced environment. The TPM will be responsible for driving internal or cross-functional teams, ensuring seamless project execution, and delivering results under changing circumstances. This is an opportunity to work on a diverse range of projects and make a significant impact on the organization’s success.
Role
- The principle TPM will play a critical role in planning and executing the delivery of technical vision and roadmap, unlocking synergies across our platforms, data assets and business units.
- The TPM will act as a central point of coordination for infrastructure and cloud capabilities for various R&D teams distributed across around the globe to drive standardization, alignment across initiatives, and ensure global program governance best practices.
- Continuously work on finding ways to optimize manual processes with a lens of automation and help improve program execution in the new AI native world.
- Act as the program liaison, provide specific direction for product development initiatives, supporting teams to ensure that all program engagements meet timelines and scope expectations.
- Develop and manage flexible project plans, adapting to shifting business priorities and requirements.
- Drive execution of strategic initiatives through successful delivery by organizing a group of related technology projects or activities across multiple teams, aligning dependent organizations to ensure coordinated delivery.
- Identify and remove barriers, finding the path forward in challenging situations to ensure timely and effective project completion.
- Effectively monitor, control, and report on project execution, adapt communication strategies to fit the urgency and complexity of different projects providing accurate status updates to executive stakeholders at appropriate intervals.
- Recognize complexity and create predictable delivery paths for large and/or complex efforts, while measurably improving, streamlining, and eliminating excess processes.
- Manage relationships with vendors including SOW creation, amendments, termination, resource onboarding, financial tracking.
All About You
- Proven knowledge and demonstrated expertise in the areas of strategy, planning and project management required processes and techniques.
- Strong leadership, interpersonal, relationship-building and communication skills required with a solid track record for developing internal and external relationships.
- Ability to communicate complex issues & decisions in a clear and concise summary to executives, peers, and staff.
- Demonstrate a high level of creative problem-solving, a strong personal presence, manage change, thrive when dealing with uncertainty, and demonstrate a focus on execution, and organization.
- Demonstrate strong planning, multi-tasking, prioritization and re-prioritization abilities.
- Encourage a culture of continuous improvement by leveraging lessons learned from previous projects.
- Demonstrate strong thinking across technology and business with strong execution track record.
- Have Excellent Problem-Solving skills - pursues alternative ways to solve problems, address difficult situations, and produce actionable recommendations.
- Exhibit tenacity, encourages healthy debate, and challenges conventional thinking.
- Experience with technical program management and working knowledge and exposure to AI best practices for program execution in an AI native development environment.
- Knowledge and experience of working with Mastercard’s shared services teams and experience deploying global applications on cloud platforms is a definite plus.
Mastercard is a merit-based, inclusive, equal opportunity employer that considers applicants without regard to gender, gender identity, sexual orientation, race, ethnicity, disabled or veteran status, or any other characteristic protected by law. We hire the most qualified candidate for the role. In the US or Canada, if you require accommodations or assistance to complete the online application process or during the recruitment process, please contact reasonable_accommodation@mastercard.com and identify the type of accommodation or assistance you are requesting. Do not include any medical or health information in this email. The Reasonable Accommodations team will respond to your email promptly.
Corporate Security Responsibility
All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must:
- Abide by Mastercard’s security policies and practices;
- Ensure the confidentiality and integrity of the information being accessed;
- Report any suspected information security violation or breach, and
- Complete all periodic mandatory security trainings in accordance with Mastercard’s guidelines.
In line with Mastercard’s total compensation philosophy and assuming that the job will be performed in the US, the successful candidate will be offered a competitive base salary and may be eligible for an annual bonus or commissions depending on the role. The base salary offered may vary depending on multiple factors, including but not limited to location, job-related knowledge, skills, and experience. Mastercard benefits for full time (and certain part time) employees generally include: insurance (including medical, prescription drug, dental, vision, disability, life insurance); flexible spending account and health savings account; paid leaves (including 16 weeks of new parent leave and up to 20 days of bereavement leave); 80 hours of Paid Sick and Safe Time, 25 days of vacation time and 5 personal days, pro-rated based on date of hire; 10 annual paid U.S. observed holidays; 401k with a best-in-class company match; deferred compensation for eligible roles; fitness reimbursement or on-site fitness facilities; eligibility for tuition reimbursement; and many more. Mastercard benefits for interns generally include: 56 hours of Paid Sick and Safe Time; jury duty leave; and on-site fitness facilities in some locations.
Pay Ranges
O'Fallon, Missouri: $152,000 - $258,000 USD
See All 44 Technical Program Manager Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find JobsTechnical Program Manager Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Technical Program Manager Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- Mastercard14

- Affirm2

- Clayco2

- Core & Main2

- Cushman & Wakefield2

Top Industries Hiring
- Technology & Software11
- Construction & Real Estate5
- Consulting & Professional Services3
- Education3
- Healthcare & Medical Services3
What Missouri Employers Look For
The qualifications that appear most often in technical program manager jobs across Missouri.
- Bachelor's degree in computer science, engineering, or a related technical field
- 5 or more years managing large-scale, cross-functional technical programs end to end
- Proficiency with program management tools such as Jira, Confluence, or Asana
- Experience driving alignment across engineering, product, and executive stakeholders
- PMP, PgMP, or equivalent program management certification preferred
- Familiarity with agile and waterfall delivery methodologies in a software environment
Technical Program Manager Jobs in Missouri: Frequently Asked Questions
How many technical program manager jobs are there in Missouri?
There are 44+ technical program manager openings in Missouri on Migrate Mate as of June 2026, with the most roles in O'Fallon, Kansas City, and St. Louis. New positions post regularly as employers across Missouri hire.
How much do technical program managers make in Missouri?
Technical program managers in Missouri earn a median of about $159,460 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $95,690 for the lowest 10% to over $216,330 for the top 10%. Pay rises with experience, specialty, and employer.
Which Missouri cities have the most technical program manager jobs?
O'Fallon, Kansas City, and St. Louis have the most technical program manager openings in Missouri right now, with additional roles spread across smaller metros statewide.
Which companies hire technical program managers in Missouri?
Employers hiring technical program managers in Missouri include Mastercard, Affirm, and Clayco, based on current listings on Migrate Mate as of June 2026.
Are there remote technical program manager jobs in Missouri?
Yes. About 18% of technical program manager openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.
How do I apply for technical program manager jobs in Missouri?
You can apply to technical program manager jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.
See All 44 Technical Program Manager Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Jobs