Technical Program Manager Jobs in Missouri
Technical Program Manager jobs in Missouri are concentrated in St. Louis, Kansas City, and Columbia, where companies like Boeing, Cerner (now Oracle Health), and Mastercard maintain significant technology operations and hire regularly at mid-level to senior levels. The most active specialties in Missouri's market include cloud infrastructure delivery, healthcare IT program management, and defense and aerospace systems coordination. Demand is steady across both enterprise software and regulated-industry environments, making Missouri one of the more consistent markets for this role in the Midwest. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 11+ Technical Program Manager jobs











Our Purpose
Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential.
Title and Summary
Senior Technical Program Manager Overview:In Corporate Solutions, we empower our customer’s businesses to succeed through innovative, trusted payment solutions that deliver a seamless digital-first experience around the world. We are disrupting the industry by developing world-class travel and B2B solutions for our corporate clients around the globe.
As a key player in our organization, you will play a critical role in revolutionizing the global financial ecosystem. You will have the opportunity to make data-driven decisions, build first-in-class corporate solutions, and partner with industry-leaders to build cloud-native products and solutions for our clients.
Role:
- Plan, execute, and deliver projects from inception to completion related to a known technology, product, or program. Describes and maintains the integrated plan that accounts for internal/external dependencies, differing delivery approaches, numerous constraints, and contingency for unplanned delays
- Proactively manage the end-to-end delivery of engineering work through the organization and all dependent organizations, reporting out progress, ensuring dependencies are covered, overseeing the gaps between teams, processes, and systems, while removing all blocking issues leading to a successful delivery.
- Accelerates progress by driving crisp, timely decisions
- Looked to as first point of contact for projects. Can communicate with confidence. levels up. Is the source of truth for status. Transforms raw thoughts into clear and concise communications. Provides right information and associated data about the state of the project to the right audience at the right time. Runs effective meetings
- Has experience in and understands industry technologies. Understands their program, product, or Technology domain. Sufficient depth/credibility to be effective with teams they work with. Can competently represent team’s services to stakeholders and other teams. May need to bring developers or SMEs to meetings to talk details
- Nurtures good working relationships with engineers, managers, and peers
- Drive the execution of an initiative that may span multiple teams and integrations, reporting meaningful status along the way.
- Coach your teams on self-organization and working effectively cross-functionally.
All About You:
- You operate with independence and autonomy.
- You have experience defining and building cloud-native services at scale with a deep understanding of the service’s capabilities and underlying technologies.
- You have experience breaking down problems, organizing work, planning sprints, and delivering technical programs using Agile delivery models (Scrum, Kanban, etc.)
- You have a track record of data driven decision-making and applying continuous improvement methodologies across teams.
- You can debate the delivery strategy with business teams, architects, engineers, and designers.
- You can communicate to executives, peers, and staff with impact, eloquence, and authenticity.
- You have experience building relationships, partnering with and influencing teams while commanding the respect of the individuals you work with across the organization.
- You have in-depth experience in SAFe or Scrum@Scale practices and have worked in large-scale team environments.
- You thrive in an Agile environment focused on continuous improvement.
- You are passionate about the art of delivering the highest quality software to customers and doing the right thing.
- Broad understanding of Software Engineering Concepts/Methodologies
- Huge plus if you have expertise in Payments, IaaS, PaaS, CI/CD, Microservice APIs, DevOps and Agentic AI
Education:
- Bachelor's degree in information systems, Information Technology, Computer Science or Engineering or equivalent work experience
Corporate Security Responsibility
All activities involving access to Mastercard assets, information, and networks comes with an inherent risk to the organization and, therefore, it is expected that every person working for, or on behalf of, Mastercard is responsible for information security and must:
Abide by Mastercard’s security policies and practices;
Ensure the confidentiality and integrity of the information being accessed;
Report any suspected information security violation or breach, and
Complete all periodic mandatory security trainings in accordance with Mastercard’s guidelines.
Pay Ranges
O'Fallon, Missouri: $96,000 - $163,000 USDSee All 11 Technical Program Manager Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find JobsTechnical Program Manager Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Technical Program Manager Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Electronics & Hardware
What Missouri Employers Look For
The qualifications that appear most often in technical program manager jobs across Missouri.
- Bachelor's degree in computer science, engineering, or a related technical field required
- Five or more years managing cross-functional technical programs from initiation through delivery
- Demonstrated experience with Agile, Scrum, or SAFe frameworks in large-scale environments
- PMP or similar project management certification strongly preferred by Missouri employers
- Proficiency with program tracking tools such as Jira, Confluence, or Microsoft Project
- Strong stakeholder communication skills with experience presenting to executive leadership
Technical Program Manager Jobs in Missouri: Frequently Asked Questions
How do you become a technical program manager in Missouri?
Most technical program manager roles in Missouri require a bachelor's degree in a technical discipline such as computer science, software engineering, or information systems, followed by several years of hands-on project or program delivery experience. Missouri does not issue a state-specific license for this role. Employers here place strong weight on credentials like the PMP from the Project Management Institute and demonstrated experience leading technology programs in regulated industries such as healthcare IT or aerospace.
How much do technical program managers make in Missouri?
Technical program managers in Missouri earn a median of about $159,460 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $95,690 for the lowest 10% to over $216,330 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire technical program managers in Missouri?
Employers hiring technical program managers in Missouri right now include Mastercard, Trane Technologies, and Google, based on current listings on Migrate Mate as of September 2026. Missouri's concentration of defense contractors, healthcare technology firms, and financial services companies means demand for this role is distributed across multiple high-compliance sectors.
Which Missouri cities have the most technical program manager jobs?
O'Fallon, St. Louis, and Fenton lead Missouri for technical program manager openings. St. Louis anchors demand through its aerospace, defense, and healthcare IT employers, Kansas City draws hiring from financial technology and logistics firms, and Columbia benefits from the University of Missouri system's growing technology and research programs alongside regional healthcare networks.
Are there remote technical program manager jobs in Missouri?
Yes, and more than most fields. About 71% of technical program manager openings tied to Missouri are remote or hybrid as of September 2026, reflecting that program coordination, roadmap planning, and stakeholder communication translate well to distributed teams. Program phases requiring on-site presence, such as vendor reviews or launch support, are more likely to pull candidates back into Missouri offices temporarily.
How can I get hired as a technical program manager in Missouri with little or no experience?
The most realistic entry path is moving laterally from a technical role such as software developer, systems analyst, or QA engineer into a junior program coordinator or associate program manager position. Large Missouri employers like Boeing and Oracle Health run rotational and associate program tracks that draw from internal technical staff. Earning a Certified Associate in Project Management credential and building a portfolio of cross-functional initiatives, even informal ones, signals readiness to Missouri hiring managers reviewing candidates without direct program management titles.
Where can I find and apply to technical program manager jobs in Missouri?
You can find and apply to technical program manager jobs in Missouri on Migrate Mate, which lists current Missouri openings across industries and experience levels. Find roles that fit your background and apply directly to the employers posting them.
See All 11 Technical Program Manager Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Jobs