Biotech & Pharma Visa Sponsorship Jobs in South Dakota
South Dakota's biotech and pharmaceutical sector centers around Sioux Falls and Rapid City, with companies like Roche Dakota and Pathology Associates driving innovation. The state's research universities, including South Dakota State University, create pathways for international talent in drug development, medical device manufacturing, and clinical research roles.
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We are seeking a highly motivated Principal Scientist I with extensive AAV gene therapy manufacturing experience to develop state-of-the-art downstream purification processes for next-generation AAV gene therapy. This role is also responsible for executing early-stage process development with the focus on developability of AAV gene therapy lead candidates as well as new platform process development for existing and novel AAV capsids and cargo vectors.
About The Role
Internal Job Title: Principal Scientist I/II
Position Location: Onsite, San Diego, CA
Key Responsibilities
- Lead and manage a 3-5 person downstream process team and provide technical support, training, and SME knowledge to assist with the professional development of direct reports.
- Coordinate activities with associates across upstream process and analytical teams.
- Develop strategies in collaboration with Disease Areas and partner with various line functions to support early drug discovery from target selection and validation through lead compound selection and developability assessment.
- Serve as a subject matter expert to transfer manufacturing process knowledge to Technical Research & Development team and advance pipeline programs into clinical phases.
- Lead effort and work collaboratively with Technical Research & Development to develop innovative and cost-effective downstream processes for next-generation AAV.
- Manage multiple project workflow to ensure timely delivery.
- Prepare written reports conforming to defined documentation practices including electronic lab notebook.
- Other related duties as assigned.
Essential Requirements
- PhD in bioprocessing, biochemical engineering, gene therapy or a related field with 3+ years of relevant process development experience in biotechnology/pharmaceutical environment.
- Experience in people management.
- Knowledge of downstream purification processes including affinity and ion-exchange chromatography with hands-on experience with AKTA purification systems.
- Technical proficiency, creativity, and independent thoughts.
- Effective communication skills to convey scientific concepts to research scientists and cross-functional collaborators.
- Strong organization and problem-solving skills with attention to details.
- Ability to work in a fast-paced and matrix environment.
Desired Requirements
- Experiences in AAV gene therapy.
- Experience with viral gene therapy.
The salary for this position is expected to range between $108,500 and $201,500 per year for Principal Scientist I, and between $119,700 and $222,300 per year for Principal Scientist II. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
Why Novartis:
Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?
Benefits and Rewards:
Learn about all the ways we’ll help you thrive personally and professionally. Read our handbook (PDF 30 MB)
EEO Statement
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Summary
We are seeking a highly motivated Principal Scientist I with extensive AAV gene therapy manufacturing experience to develop state-of-the-art downstream purification processes for next-generation AAV gene therapy. This role is also responsible for executing early-stage process development with the focus on developability of AAV gene therapy lead candidates as well as new platform process development for existing and novel AAV capsids and cargo vectors.
About The Role
Internal Job Title: Principal Scientist I/II
Position Location: Onsite, San Diego, CA
Key Responsibilities
- Lead and manage a 3-5 person downstream process team and provide technical support, training, and SME knowledge to assist with the professional development of direct reports.
- Coordinate activities with associates across upstream process and analytical teams.
- Develop strategies in collaboration with Disease Areas and partner with various line functions to support early drug discovery from target selection and validation through lead compound selection and developability assessment.
- Serve as a subject matter expert to transfer manufacturing process knowledge to Technical Research & Development team and advance pipeline programs into clinical phases.
- Lead effort and work collaboratively with Technical Research & Development to develop innovative and cost-effective downstream processes for next-generation AAV.
- Manage multiple project workflow to ensure timely delivery.
- Prepare written reports conforming to defined documentation practices including electronic lab notebook.
- Other related duties as assigned.
Essential Requirements
- PhD in bioprocessing, biochemical engineering, gene therapy or a related field with 3+ years of relevant process development experience in biotechnology/pharmaceutical environment.
- Experience in people management.
- Knowledge of downstream purification processes including affinity and ion-exchange chromatography with hands-on experience with AKTA purification systems.
- Technical proficiency, creativity, and independent thoughts.
- Effective communication skills to convey scientific concepts to research scientists and cross-functional collaborators.
- Strong organization and problem-solving skills with attention to details.
- Ability to work in a fast-paced and matrix environment.
Desired Requirements
- Experiences in AAV gene therapy.
- Experience with viral gene therapy.
The salary for this position is expected to range between $108,500 and $201,500 per year for Principal Scientist I, and between $119,700 and $222,300 per year for Principal Scientist II. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors. Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
Why Novartis:
Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?
Benefits and Rewards:
Learn about all the ways we’ll help you thrive personally and professionally. Read our handbook (PDF 30 MB)
EEO Statement
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Biotech & Pharma Job Roles in South Dakota
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Search Biotech & Pharma Jobs in South DakotaBiotech & Pharma Jobs in South Dakota: Frequently Asked Questions
Which biotech & pharma companies sponsor visas in South Dakota?
Major sponsors include Roche Dakota in Sioux Falls, Pathology Associates, and regional medical device manufacturers. Academic medical centers like Sanford Health and Avera Health Systems also sponsor research positions. Smaller biotech startups and contract research organizations throughout the state increasingly offer H-1B visa and other visa sponsorships for specialized roles.
How to find biotech & pharma visa sponsorship jobs in South Dakota?
Use Migrate Mate to filter biotech and pharmaceutical positions specifically in South Dakota. The platform shows companies with proven H-1B sponsorship history in the state. Focus your search on Sioux Falls and Rapid City, where most opportunities concentrate, and consider both private companies and university-affiliated research positions.
Which visa types are most common for biotech & pharma roles in South Dakota?
H-1B visas dominate for research scientist, biostatistician, and regulatory affairs positions. O-1 visas apply to senior researchers with distinguished achievements. F-1 to H-1B transitions are common through university partnerships with South Dakota State University and University of South Dakota. TN visas work for Canadian and Mexican nationals in qualifying scientific roles.
Which cities in South Dakota have the most biotech & pharma sponsorship jobs?
Sioux Falls leads with the highest concentration, hosting major pharmaceutical operations and research facilities. Rapid City offers opportunities in medical device development and clinical research. Brookings, home to South Dakota State University, provides academic research positions. Aberdeen and Pierre have smaller but growing life sciences sectors.
What are the prevailing wage considerations for biotech & pharma roles in South Dakota?
South Dakota's lower cost of living affects prevailing wage determinations for H-1B applications. Research scientist and biostatistician positions typically meet Level 2-3 wage requirements easily. Clinical research roles may require careful wage level justification. University-sponsored positions often fall under different wage calculation methods than private sector roles.
What is the prevailing wage for sponsored biotech & pharma jobs in South Dakota?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.