Group Chief Operating Officer Jobs in USA with Visa Sponsorship
Group Chief Operating Officer roles sit at the top of the specialty occupation ladder, making H-1B visa and O-1A visas the most viable sponsorship paths. Employers filing an LCA must document executive-level prevailing wages, and candidates with cross-border operational portfolios have a clear credential advantage in adjudication.
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Get Access To All JobsJob Title: Executive Director, Global Clinical Operations Study Management Group Head
Job Requisition ID: 2481
Posting Start Date: 10/29/26
At Daiichi Sankyo, we are united by a single purpose, to improve lives around the world through innovative medicines. With a legacy of innovation since 1899, a presence in more than 30 countries, and more than 19,000 employees, we are advancing breakthrough therapies in oncology, cardiovascular disease, rare diseases, and immune disorders. Guided by our 2030 vision to "be an innovative global healthcare company contributing to the sustainable development of society", we are shaping a healthier, more hopeful future for patients, their families, and society.
Job Summary
The Executive Director, Global Clinical Operations Study Management Group Head has leadership and overall strategic oversight of study management and delivery for all therapeutic areas. The role reports into the Global Clinical Operations VP and is accountable for ensuring the clinical trial portfolio and submissions are delivered to time, quality, and cost. The teams reporting into this role must ensure robust strategic and operational planning has been incorporated throughout the governance process, to oversee delivery of projects to plan and to drive standardization and operational excellence across a portfolio of work.
Responsibilities
-
Partner with the VP in developing the functional discipline through (i) functional-area leadership, (ii) keeping abreast with latest functional development in the pharma industry, (iii) supporting consistency, coherence, and compliance, (iv) establishing area-relevant standards, (v) encouraging innovation.
-
Build strong relationships with clinical development, clinical sciences, regulatory, biostats, data management, and other key stakeholder peer functions to ensure strong collaboration and early operational input into study design and trial delivery planning and execution.
-
Ensure scientific concepts and business priorities are considered to provide strategic global leadership for the clinical operations staff working on clinical programs in scope/portfolio.
-
Close collaboration with Asset and Portfolio Management (A&PM), GCO Clinical Trial Business Operations (CTBO), and GCO Study Optimization to assess and plan for Ph I – III study team delivery and transitions. This includes engagement with feasibility, CTD, RSEM, and site contracts and budget management.
-
Ensure delivery of all operational components of global programs within scope, either through external partners (CRO, ARO, etc) or internal delivery models.
-
Act as a key point of escalation for issues impacting across program for both internal and external stakeholders. Responsible for maintaining high level of visibility of operational topics among leadership and stakeholders.
-
Support, where needed, internal program/study review meetings preceding governance investment decision meetings.
-
Provide strategic leadership to drive projects and foster a performance driven global culture.
-
Accountable for the creation of an environment that inspires, motivates, and empowers colleagues, influence stakeholders inside and outside of GCO to accelerate clinical development timelines and to create value for patients and the healthcare system.
-
Responsible for maintaining high level of visibility of operational topics among leadership and stakeholders.
-
Functional leadership of up to 10 employees who manage the delivery.
-
Ensure capability build, individual development, and performance management.
-
Accountable for resource management within respective portfolio and collaborating with peers to optimize talent in the organization.
-
Ensure the GPT GCO reps are functioning at a high and consistent level.
-
Drives a feedback-oriented culture.
Qualifications
Education Qualifications
Bachelor's Degree required.
Experience Qualifications
-
BS/MSA in related discipline, or equivalent work experience required.
-
15+ years industry or related experience required.
-
Extensive early/late stage drug development experience ideally including time in role such as a Global Project Leader at Sr. Director level or equivalent preferred.
-
Relevant therapeutic experience and proven ability to learn new indications required.
-
Proven global line management expertise; experience of performance management and development of Director+ level staff required.
-
Proven experience in leading and implementing improvement initiatives, novel technology or techniques in the context of clinical development required.
-
Proven change management experience required.
-
Proven strategic and innovative thinking required.
-
Functional management experience, managing resourcing and budget planning/oversight required.
-
Ability to collaborate and establish a well-connected network with other Early/Late Leaders and Clinical Operations Leadership required.
-
Demonstrated ability in influencing others in a matrix environment required.
-
Awareness of external competitive environment and operational practices required.
-
Demonstrated ability to set and manage priorities, resources, performance targets and project initiatives in a global environment required.
-
Excellent written and verbal communication skills required.
-
Willingness to travel both domestic and international required.
-
Proven ability to develop successful collaborations with internal and external partners required.
-
Maintains high standards, including a commitment to Daiichi Sankyo values, policies and employment principles required.
Travel Requirements
Ability to travel up to 20% of the time. Some domestic and international travel expected.
Additional Information
Daiichi Sankyo, Inc. is an equal opportunity/affirmative action employer. Qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.
Salary Range:
USD$263,250.00 - USD$438,750.00
Job Title: Executive Director, Global Clinical Operations Study Management Group Head
Job Requisition ID: 2481
Posting Start Date: 10/29/26
At Daiichi Sankyo, we are united by a single purpose, to improve lives around the world through innovative medicines. With a legacy of innovation since 1899, a presence in more than 30 countries, and more than 19,000 employees, we are advancing breakthrough therapies in oncology, cardiovascular disease, rare diseases, and immune disorders. Guided by our 2030 vision to "be an innovative global healthcare company contributing to the sustainable development of society", we are shaping a healthier, more hopeful future for patients, their families, and society.
Job Summary
The Executive Director, Global Clinical Operations Study Management Group Head has leadership and overall strategic oversight of study management and delivery for all therapeutic areas. The role reports into the Global Clinical Operations VP and is accountable for ensuring the clinical trial portfolio and submissions are delivered to time, quality, and cost. The teams reporting into this role must ensure robust strategic and operational planning has been incorporated throughout the governance process, to oversee delivery of projects to plan and to drive standardization and operational excellence across a portfolio of work.
Responsibilities
-
Partner with the VP in developing the functional discipline through (i) functional-area leadership, (ii) keeping abreast with latest functional development in the pharma industry, (iii) supporting consistency, coherence, and compliance, (iv) establishing area-relevant standards, (v) encouraging innovation.
-
Build strong relationships with clinical development, clinical sciences, regulatory, biostats, data management, and other key stakeholder peer functions to ensure strong collaboration and early operational input into study design and trial delivery planning and execution.
-
Ensure scientific concepts and business priorities are considered to provide strategic global leadership for the clinical operations staff working on clinical programs in scope/portfolio.
-
Close collaboration with Asset and Portfolio Management (A&PM), GCO Clinical Trial Business Operations (CTBO), and GCO Study Optimization to assess and plan for Ph I – III study team delivery and transitions. This includes engagement with feasibility, CTD, RSEM, and site contracts and budget management.
-
Ensure delivery of all operational components of global programs within scope, either through external partners (CRO, ARO, etc) or internal delivery models.
-
Act as a key point of escalation for issues impacting across program for both internal and external stakeholders. Responsible for maintaining high level of visibility of operational topics among leadership and stakeholders.
-
Support, where needed, internal program/study review meetings preceding governance investment decision meetings.
-
Provide strategic leadership to drive projects and foster a performance driven global culture.
-
Accountable for the creation of an environment that inspires, motivates, and empowers colleagues, influence stakeholders inside and outside of GCO to accelerate clinical development timelines and to create value for patients and the healthcare system.
-
Responsible for maintaining high level of visibility of operational topics among leadership and stakeholders.
-
Functional leadership of up to 10 employees who manage the delivery.
-
Ensure capability build, individual development, and performance management.
-
Accountable for resource management within respective portfolio and collaborating with peers to optimize talent in the organization.
-
Ensure the GPT GCO reps are functioning at a high and consistent level.
-
Drives a feedback-oriented culture.
Qualifications
Education Qualifications
Bachelor's Degree required.
Experience Qualifications
-
BS/MSA in related discipline, or equivalent work experience required.
-
15+ years industry or related experience required.
-
Extensive early/late stage drug development experience ideally including time in role such as a Global Project Leader at Sr. Director level or equivalent preferred.
-
Relevant therapeutic experience and proven ability to learn new indications required.
-
Proven global line management expertise; experience of performance management and development of Director+ level staff required.
-
Proven experience in leading and implementing improvement initiatives, novel technology or techniques in the context of clinical development required.
-
Proven change management experience required.
-
Proven strategic and innovative thinking required.
-
Functional management experience, managing resourcing and budget planning/oversight required.
-
Ability to collaborate and establish a well-connected network with other Early/Late Leaders and Clinical Operations Leadership required.
-
Demonstrated ability in influencing others in a matrix environment required.
-
Awareness of external competitive environment and operational practices required.
-
Demonstrated ability to set and manage priorities, resources, performance targets and project initiatives in a global environment required.
-
Excellent written and verbal communication skills required.
-
Willingness to travel both domestic and international required.
-
Proven ability to develop successful collaborations with internal and external partners required.
-
Maintains high standards, including a commitment to Daiichi Sankyo values, policies and employment principles required.
Travel Requirements
Ability to travel up to 20% of the time. Some domestic and international travel expected.
Additional Information
Daiichi Sankyo, Inc. is an equal opportunity/affirmative action employer. Qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.
Salary Range:
USD$263,250.00 - USD$438,750.00
See all 3,011+ Group Chief Operating Officer Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Group Chief Operating Officer roles.
Get Access To All JobsTips for Finding Group Chief Operating Officer Jobs
Document cross-border operational scope precisely
USCIS adjudicators scrutinize COO petitions for evidence of enterprise-wide authority. Compile board resolutions, org charts showing multi-country reporting lines, and P&L responsibility letters before any employer files the LCA.
Target companies with active LCA filing history
Use Migrate Mate to find employers with verified LCA sponsorship records for senior operations roles. Boards that have sponsored COO-level positions before understand the prevailing-wage and specialty-occupation documentation the DOL requires.
Align your degree field to operations management
H-1B specialty occupation requires a directly related bachelor's degree. An MBA, engineering degree, or operations management qualification ties directly to the COO role; a loosely related field weakens the petition and invites a Request for Evidence from USCIS.
Use the OFLC Wage Search before salary negotiations
The prevailing wage for a Group COO is set by DOL and must appear on the LCA before filing. Pull the OFLC Wage Search data for your target metro and job zone so you enter offer negotiations knowing the floor your employer is legally obligated to meet.
Treat the O-1A as a parallel track, not a fallback
If H-1B lottery selection is uncertain, O-1A petitions are filed any time and have no cap. COOs with published thought leadership, board appointments, industry awards, or media coverage as operations leaders can build a credible extraordinary-ability evidentiary record.
Front-load green card eligibility into your offer negotiation
H-1B status allows dual intent, so you can pursue an EB-1C multinational manager green card concurrently if you have one year of qualifying overseas employment with the same corporate family within the prior three years. Raise this with the employer's immigration counsel at the offer stage, not after onboarding.
Frequently Asked Questions
Does a Group Chief Operating Officer role qualify as a specialty occupation for H-1B purposes?
Yes, but the employer must demonstrate that the specific COO position requires at least a bachelor's degree in a directly related field such as business administration, operations management, or engineering. Generic executive titles alone don't satisfy the test; the job duties must require theoretical and practical application of a body of specialized knowledge, which USCIS evaluates case by case.
Which visa types realistically cover a Group COO sponsorship candidate?
H-1B is the most common path, subject to the annual cap and lottery. O-1A is a strong alternative for COOs with demonstrable extraordinary ability, including press coverage, speaking engagements, board roles, or industry awards. EB-1C is the preferred green card route if you've managed a qualifying overseas affiliate for at least one year within the prior three years.
How do I find employers willing to sponsor a Group COO visa candidate?
Migrate Mate lists employers with verified sponsorship histories for senior operations roles, so you can target companies that have navigated the LCA and I-129 process for executive-level hires before. Focusing on organizations with established immigration infrastructure significantly reduces the friction of initiating sponsorship at the C-suite level.
What documentation strengthens a COO-level H-1B petition against a Request for Evidence?
USCIS frequently issues RFEs on senior-operations petitions questioning whether the role truly requires a specialized degree rather than general experience. Counter this with an independent expert opinion letter, an internal organizational chart showing reporting complexity, evidence of enterprise-wide budget authority, and the O*NET occupation profile for the role, which supports the specialty-occupation classification.
Can a Group COO candidate pursue a green card while on H-1B status?
Yes. H-1B allows dual intent, so pursuing permanent residence doesn't jeopardize your nonimmigrant status. The EB-1C multinational manager category is typically the fastest route for COOs, bypassing the PERM labor certification process entirely. For roles that don't meet EB-1C thresholds, EB-2 with PERM is the standard alternative, though priority date backlogs affect applicants born in India and China.
What is the prevailing wage requirement for sponsored Group Chief Operating Officer jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.