VP Operations Jobs in Missouri
VP Operations jobs in Missouri are concentrated in St. Louis, Kansas City, and Springfield, where major employers like Emerson Electric, Cerner (now Oracle Health), and Anheuser-Busch InBev maintain large operational footprints. Demand is strongest in manufacturing and supply chain, healthcare systems management, and logistics and distribution, reflecting Missouri's position as a central hub for both industrial and medical sector growth. Candidates range from seasoned executives stepping into group-level roles to high-performing directors ready for their first VP appointment. Scan the live roles below and apply to whichever ones fit.
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You desire impactful work.
You’re RGA ready
RGA is a purpose-driven organization working to solve today’s challenges through innovation and collaboration. A Fortune 200 Company and listed among its World’s Most Admired Companies, we’re the only global reinsurance company to focus primarily on life- and health-related solutions. Join our multinational team of intelligent, motivated, and collaborative people, and help us make financial protection accessible to all.
The Vice President, Global Infrastructure & Operations is accountable for the global strategy, operating model, financial performance, resilience, and modernization of RGA's enterprise infrastructure services across data centers, private cloud, public cloud, network, identity, and infrastructure operations. The role leads a geographically dispersed organization and strategic partners delivering secure, scalable, highly available, and cost effective services supporting RGA's global business operations. Working closely across Global Technology, Global Security, Enterprise Architecture, and business leadership, the Vice President, Global Infrastructure & Operations translates enterprise priorities into multi-year infrastructure roadmaps and is accountable for execution, service performance, risk reduction, and measurable business outcomes.
Principle Duties:
Define and execute the global Infrastructure & Operations strategy, multi-year roadmaps, and operating model in alignment with enterprise business, technology, security, and risk priorities.
Provide end-to-end leadership and accountability for RGA’s data center, private cloud, public cloud, network, identity, and infrastructure operations services, including delivery through internal teams and strategic partners.
Ensure the resilience, availability, security, scalability, and cost effectiveness of global infrastructure services. Establish service-level objectives, operational performance measures, and executive reporting, and drive sustained improvement in service reliability and customer outcomes.
Lead infrastructure modernization and transformation across hybrid cloud and globally distributed environments. Translate emerging technology and market capabilities into pragmatic investment strategies that improve agility, automation, resilience, and business value.
Provide financial stewardship for a significant global technology portfolio, including annual planning, forecasting, investment prioritization, vendor strategy, commercial negotiations, consumption management, and delivery of cost optimization commitments.
Lead, develop, and retain a high-performing, geographically dispersed leadership team and organization. Establish clear accountability, succession plans, workforce strategies, and an operating culture centered on ownership, collaboration, innovation, and operational excellence.
Partner with Enterprise Architecture, the Global Security and Privacy Office, Global Technology Delivery Centers, application and engineering leaders, and business stakeholders to establish infrastructure standards, manage technology lifecycle and risk, and enable timely delivery of enterprise initiatives
Provide executive leadership during major technology incidents and recovery events. Ensure crisis management, disaster recovery, operational resilience, and remediation programs are tested, governed, and aligned with business expectations.
Govern a portfolio of complex, enterprise-scale programs and strategic initiatives, ensuring delivery against approved scope, schedule, financial commitments, risk tolerances, and measurable outcomes.
Serve as a senior advisor to the Chief Technology Officer and Global Technology leadership on infrastructure strategy, operational risk, investment priorities, sourcing decisions, and technology transformation.
Qualifications
Education:
Bachelor’s Degree in Arts/Sciences (BA/BS) in Computer Science, Information Technology, Engineering, Business, or a related field, or an equivalent combination of education and experience required
Work Experience:
15+ Years of progressive technology leadership experience, including at least 10 years leading large-scale infrastructure and operations functions in a complex, geographically dispersed enterprise environment required
Skills & Abilities
Demonstrated experience leading leaders and developing high performing global teams, managing significant operating and capital budgets, directing strategic suppliers, and delivering complex multi-year transformation and resilience programs. required
Exceptional leadership capability with demonstrated success leading leaders, building succession depth, and producing results through a large, geographically dispersed organization. required
Highly advanced strategic planning, decision-making, and execution skills, with the ability to translate enterprise objectives into multi-year technology roadmaps, investment priorities, and measurable outcomes. required
Proven accountability for global, business-critical infrastructure and operations services in a complex hybrid technology environment. required
Demonstrated ability to lead enterprise transformation, operational resilience, and risk-reduction programs involving multiple technology domains, business stakeholders, and strategic partners. required
Deep knowledge of infrastructure technologies and operating models, including data centers, networking, identity, hybrid cloud, automation, observability, service management, disaster recovery, and technology lifecycle management. required
Strong business and financial acumen, including experience managing significant budgets, optimizing technology consumption, evaluating investment tradeoffs, and conducting complex vendor and sourcing negotiations. required
Executive presence and influence, with the ability to communicate complex technology, operational, financial, and risk matters clearly to senior executives and stakeholders across global markets. required
Ability to establish governance, performance measures, service-level objectives, and accountability mechanisms that improve reliability, cost effectiveness, delivery velocity, and customer outcomes. required
Outstanding collaboration and relationship-management skills, with demonstrated effectiveness across Enterprise Architecture, cybersecurity, engineering, application delivery, procurement, risk, and business leadership. required
Continuous learning orientation and demonstrated ability to apply emerging technologies and industry practices to improve resilience, customer service, efficiency, and competitive advantage. required
#LI-HYBRID #LI-MC1
What you can expect from RGA:
Gain valuable knowledge from and experience with diverse, caring colleagues around the world.
Enjoy a respectful, welcoming environment that fosters individuality and encourages pioneering thought.
Join the bright and creative minds of RGA, and experience vast, endless career potential.
We’re excited to get to know you and connect your unique skills with our global opportunities. To create a modern and seamless experience, we use artificial intelligence (AI) in parts of our preliminary screening process. This technology helps us personalize job recommendations, automate interview scheduling, evaluate candidates based solely on experience—without considering name, gender, or other personal details—and provide real-time answers through our chatbot. AI is used only during early screening and never makes hiring decisions. Your RGA recruiter will work closely with you every step of the way to ensure the process feels personal, thoughtful, and focused on you.
Compensation Range:
$215,150.00 - $320,730.00 AnnualBase pay varies depending on job-related knowledge, skills, experience and market location. In addition, RGA provides an annual bonus plan that includes all roles and some positions are eligible for participation in our long-term equity incentive plan. RGA also maintains a full range of health, retirement, and other employee benefits.
RGA is an equal opportunity employer. Qualified applicants will be considered without regard to race, color, age, gender identity or expression, sex, disability, veteran status, religion, national origin, or any other characteristic protected by applicable equal employment opportunity laws.
See All 9 VP Operations Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find VP Operations JobsVP Operations Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
VP Operations Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring


What Missouri Employers Look For
The qualifications that appear most often in VP operations jobs across Missouri.
- Bachelor's degree in business, operations management, or a related field required
- Ten or more years of progressive operations leadership experience in a relevant industry
- Demonstrated experience managing P&L responsibility across multi-site or enterprise operations
- Strong background in supply chain, manufacturing, or healthcare operations specific to Missouri markets
- Proficiency with ERP systems such as SAP or Oracle in large-scale operational environments
- Proven ability to lead cross-functional teams and drive continuous improvement initiatives
VP Operations Jobs in Missouri: Frequently Asked Questions
How do you become a vp operations in Missouri?
Most vp operations roles in Missouri require a bachelor's degree in business administration, operations management, engineering, or a related field, with many employers preferring an MBA. Missouri does not issue a state license specific to this role, but candidates typically build toward it through a progression from operations manager or director-level positions within Missouri's dominant sectors, including manufacturing, healthcare, and logistics. Professional credentials like a PMP or Lean Six Sigma certification strengthen candidacy significantly.
How much do VP operationses make in Missouri?
VP operationses in Missouri earn a median of about $79,300 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $42,460 for the lowest 10% to over $188,820 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire vp operationss in Missouri?
Missouri vp operations roles are posted by Midwest BankCentre, RGA, and USSM and others right now, based on current listings on Migrate Mate as of September 2026. Missouri's mix of Fortune 500 headquarters, major health systems, and regional manufacturing companies creates consistent executive-level operations demand throughout the year.
Which Missouri cities have the most vp operations jobs?
St. Louis, Kansas City, and Missouri account for the largest concentration of vp operations openings in Missouri. St. Louis drives volume through its deep manufacturing, bioscience, and financial services base, while Kansas City pulls demand from its logistics, healthcare, and technology sectors, with Springfield contributing through regional healthcare networks and distribution operations anchored in the southwest corridor.
Are there remote vp operations jobs in Missouri?
Yes, but they're less common than in purely desk-based fields, since vp operations roles typically require direct oversight of facilities, teams, and processes. About 100% of vp operations openings tied to Missouri are remote or hybrid as of September 2026, with most flexible arrangements concentrated in corporate strategy, vendor management, and reporting functions rather than plant or site leadership.
How can I get hired as a vp operations in Missouri with little or no experience?
The most realistic path is securing a director of operations or senior operations manager role first, then building toward a VP appointment from within a Missouri organization. Large Missouri employers in healthcare, such as BJC HealthCare and SSM Health, and manufacturers like Boeing's St. Louis operations, often promote from within and offer structured leadership development programs. Earning a Lean Six Sigma Green or Black Belt and taking on P&L ownership in a current role are the credentials that move candidates forward fastest.
Where can I find and apply to vp operations jobs in Missouri?
You can find and apply to vp operations jobs in Missouri on Migrate Mate, which lists current Missouri openings updated regularly. Search the available roles, identify the ones that match your background and target industry, and apply directly to the positions that fit your experience level and location preference.
See All 9 VP Operations Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find VP Operations Jobs