Chief Operating Officer Jobs in Missouri

Chief Operating Officer jobs in Missouri concentrate heavily in healthcare systems, financial services, and logistics, with the state's central geography making it a hub for distribution-focused operations leadership. Kansas City and St. Louis anchor the majority of openings, followed by Springfield, where regional health networks and mid-market manufacturers seek experienced operations executives. Major employers with a lasting COO-level presence include Centene Corporation, Edward Jones, and Cerner (now Oracle Health). The most in-demand specialties are healthcare operations, supply chain leadership, and multi-site business management. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles50
Top employerWashington University in St. Louis
Top citySt. Louis, MO
Cities hiring15
Work type53% On-site
Top industryConsulting

Showing 5 of 50+ Chief Operating Officer jobs

Missouri S&T
Assistant Athletic Director for Facilities, Game Operations, and Sponsorships
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Missouri S&T
Added 1d ago
Assistant Athletic Director for Facilities, Game Operations, and Sponsorships
Missouri S&T
Rolla, Missouri
Business Development
Growth Marketing
Marketing
Bachelor's degree

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Washington University in St. Louis
Assistant Director Facilities Engineering - Enterprise Physical Operations
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Washington University in St. Louis
Added 1d ago
Assistant Director Facilities Engineering - Enterprise Physical Operations
Washington University in St. Louis
St. Louis, Missouri
Engineering (Non-Software)
Maintenance & Repair
Specialized Engineering
$96k - $169k/yr
Bachelor's degree in engineering
10,000+

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United Way
Director of Operations
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United Way
Added 1d ago
Director of Operations
United Way
Kansas City, Missouri
Business Development
Growth Marketing
Marketing
Bachelor's degree in business
11-50

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RGA
SVP, Chief Operating Officer Global Finance
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RGA
Added 2d ago
SVP, Chief Operating Officer Global Finance
RGA
Chesterfield, Missouri
Clinical Support
Healthcare Administration
Medical Specialists
$324k - $480k/yr
Hybrid
Bachelor's degree in finance
1,001-5,000

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University Missouri St.Louis
Assistant Athletic Director for Facilities & Operations
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University Missouri St.Louis
Added 2d ago
Assistant Athletic Director for Facilities & Operations
University Missouri St.Louis
St. Louis, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
$58k - $620k/yr
Master's degree in business administration
201-500

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See All 50 Chief Operating Officer Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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Chief Operating Officer Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

Chesterfield
4 jobs
Springfield
3 jobs
Rolla
2 jobs
Columbia
2 jobs
Belton
1 job
Nevada
1 job
Pacific
1 job

Chief Operating Officer Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Washington University in St. Louis
Washington University in St. Louis4 open roles
CRB
CRB2 open roles
Key Rehabilitation
Key Rehabilitation2 open roles

Top Industries Hiring

  • Consulting & Professional Services
  • Education
  • Accounting & Auditing
  • Media & Entertainment
  • Technology & Software

What Missouri Employers Look For

The qualifications that appear most often in chief operating officer jobs across Missouri.

  • Bachelor's degree in business administration, operations management, or a related field required
  • Ten or more years of progressive leadership experience in operations or general management
  • Demonstrated experience managing P&L responsibility across multiple business units
  • Strong background in process improvement methodologies such as Lean or Six Sigma
  • Experience leading cross-functional teams of fifty or more employees at the director level
  • Proficiency with enterprise resource planning systems and data-driven performance reporting

Chief Operating Officer Jobs in Missouri: Frequently Asked Questions

How do you become a chief operating officer in Missouri?

Becoming a chief operating officer in Missouri typically requires a bachelor's degree in business, operations, or a related field, with many employers preferring an MBA. There is no state-issued license specific to the COO role in Missouri. The common path runs through progressive leadership positions, often director of operations or VP-level roles, within Missouri's dominant sectors: healthcare systems, financial services, and logistics companies headquartered in Kansas City or St. Louis.

How much do chief operating officers make in Missouri?

Chief operating officers in Missouri earn a median of about $172,320 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $75,040 for the lowest 10% to over $416,060 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire chief operating officers in Missouri?

Companies currently hiring chief operating officers in Missouri include Washington University in St. Louis, CRB, and Key Rehabilitation, per current listings on Migrate Mate as of August 2026. Missouri's concentration of large health systems, regional banks, and national logistics firms means COO demand is especially active in those sectors across Kansas City and St. Louis.

Which Missouri cities have the most chief operating officer jobs?

St. Louis, Kansas City, and Chesterfield account for the most chief operating officer openings in Missouri. St. Louis and Kansas City drive the bulk of demand because they are home to the state's largest corporate headquarters, major hospital networks, and financial institutions, while Springfield's growing healthcare and manufacturing base contributes a steady share of regional COO openings.

Are there remote chief operating officer jobs in Missouri?

Yes, but they're rare. The chief operating officer role is fundamentally hands-on, requiring direct oversight of people, facilities, and cross-functional teams, which limits remote flexibility. About 47% of chief operating officer openings tied to Missouri are remote or hybrid as of August 2026, with hybrid arrangements more common than fully remote. Strategic and financial oversight responsibilities are the parts of the role most likely to be performed off-site.

How can I get hired as a chief operating officer in Missouri with little or no experience?

The most realistic entry path is through an operations manager or director of operations role at a Missouri-based organization, then building toward the COO seat over several years. Large Missouri employers such as BJC HealthCare, Mercy Health, and Kansas City-area logistics firms run formal management development programs that accelerate this path. Earning an MBA from a Missouri institution like Washington University in St. Louis or the University of Missouri adds weight to a candidacy, and demonstrated P&L ownership in a director-level role is the credential that most consistently opens the door.

Where can I find and apply to chief operating officer jobs in Missouri?

You can find and apply to chief operating officer jobs in Missouri on Migrate Mate, which lists current Missouri openings updated regularly. Search the listings to find roles that match your experience level, sector, and preferred location, then apply directly to whichever positions fit your background.

See All 50 Chief Operating Officer Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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