Clinic Director Jobs in South Carolina

Clinic Director jobs in South Carolina are in steady demand, concentrated in hospital-affiliated outpatient clinics, physical and occupational therapy practices, and behavioral health centers across the state. The most active hiring markets are Columbia, Charleston, and Greenville, where employers such as Prisma Health, MUSC Health, and Bon Secours anchor a large share of openings. The most in-demand specialties are physical therapy clinic leadership, behavioral health program management, and multi-site primary care coordination. See the openings below and apply to the ones that match your experience.

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Overview

Open roles17
Top employerConcentra
Top cityGreenville, SC
Cities hiring15
Work type100% On-site
Top industryHealthcare

Showing 5 of 17+ Clinic Director jobs

Practice Director- Okatie Clinic
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Added 4d ago
Practice Director- Okatie Clinic
Your Health Organization
Hardeeville, South Carolina
Business Strategy
Consulting & Professional Services
Strategy & Corporate Development
$60k - $80k/yr
1,001-5,000

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Practice Director- Okatie Clinic
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Added 4d ago
Practice Director- Okatie Clinic
Your Health Organization
Okatie, South Carolina
Business Strategy
Consulting & Professional Services
Strategy & Corporate Development
$60k - $80k/yr
1,001-5,000

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Clinic Director - Knightsville De Novo
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Added 4d ago
Clinic Director - Knightsville De Novo
BenchMark Physical Therapy
Knightsville, South Carolina
Clinical Support
Healthcare Administration
Mental & Behavioral Health
$73k - $95k/yr
1,001-5,000

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Clinic Director Physical Therapist
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Added 6d ago
Clinic Director Physical Therapist
Carolina PT
Columbia, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Physical Therapy
CPR Certification
11-50

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Clinic Director
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Added 1w ago
Clinic Director
ATI Physical Therapy
Greenville, South Carolina
Executive Leadership & C-Suite
Program Management
Project Management
5,001-10,000

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See All 17 Clinic Director Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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Clinic Director Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greenville
2 jobs
Goose Creek
2 jobs
York
1 job
Greer
1 job
Ladson
1 job
Okatie
1 job
Sumter
1 job
Anderson
1 job
Barnwell
1 job

Clinic Director Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Concentra2 open roles
Your Health Organization2 open roles
Rehab Employee Services2 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What South Carolina Employers Look For

The qualifications that appear most often in clinic director jobs across South Carolina.

  • Active South Carolina healthcare administrator or clinical license recognized by the South Carolina Department of Labor, Licensing and Regulation
  • Master's degree in healthcare administration, public health, nursing, or a related clinical field
  • Minimum of three to five years of progressive clinical or healthcare management experience
  • Demonstrated experience managing clinical staff, budgets, and compliance with state and federal regulations
  • Proficiency with electronic health record systems and healthcare operations software
  • Strong knowledge of CMS and Joint Commission accreditation standards and quality improvement processes

Clinic Director Jobs in South Carolina: Frequently Asked Questions

How do you become a clinic director in South Carolina?

Most clinic director roles in South Carolina require a graduate-level degree in healthcare administration, nursing, or a clinical specialty, combined with prior supervisory experience in a clinical setting. South Carolina does not issue a single universal clinic director license, but many roles require an active professional license through the South Carolina Department of Labor, Licensing and Regulation, such as a nursing, physical therapy, or social work license, depending on the clinical focus of the facility.

Which companies hire clinic directors in South Carolina?

Companies currently hiring clinic directors in South Carolina include Concentra, Your Health Organization, and Rehab Employee Services, per current listings on Migrate Mate as of October 2026. South Carolina's largest health systems, including Prisma Health and MUSC Health, are among the most consistent sources of clinic director openings across the state.

Which South Carolina cities have the most clinic director jobs?

Greenville, Goose Creek, and York have the most clinic director openings in South Carolina. Columbia leads as the state capital and home to Prisma Health's flagship operations, while Charleston's concentration of MUSC Health facilities and Greenville's growing Bon Secours footprint drive strong demand in those metros.

Are there remote clinic director jobs in South Carolina?

Yes, but they're rare. Clinic director roles are predominantly on-site because the position involves direct oversight of clinical staff, patient flow, and facility operations. About 0% of clinic director openings tied to South Carolina are remote or hybrid as of October 2026, and those positions tend to involve administrative or multi-site coordination responsibilities rather than hands-on clinical management.

How can I get hired as a clinic director in South Carolina with little or no experience?

The most realistic entry path is moving into a clinic director role from an assistant director, practice manager, or lead clinician position at a South Carolina health system. Prisma Health and MUSC Health both offer clinical leadership development programs that prepare high-performing staff for management roles. Holding an active South Carolina clinical license and completing a graduate certificate in healthcare administration significantly strengthens a candidate's profile when competing against more experienced applicants.

Where can I find and apply to clinic director jobs in South Carolina?

You can find and apply to clinic director jobs in South Carolina on Migrate Mate, which lists current openings tied to the state. Search the listings, find the roles that fit your experience and location, and apply directly to the ones that are the right match.

See All 17 Clinic Director Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Clinic Director Jobs