Clinical Pharmacist Jobs in South Carolina
Clinical Pharmacist jobs in South Carolina are concentrated in Columbia, Greenville, and Charleston, where major health systems including Prisma Health, MUSC Health, and Bon Secours St. Francis drive consistent hiring across ambulatory care, oncology, and critical care settings. Demand runs from new PharmD graduates entering residency-to-hire pipelines through experienced specialists in anticoagulation, infectious disease, and transitions of care. The state's growing hospital infrastructure and academic medical center activity keep the market among the more active ones in the Southeast. See the openings below and apply to the ones that match your experience.
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Thank you for considering a career at Roper St. Francis Healthcare!
HOURS:
35hrs./week - Flexible, 8:00am - 3:30pm. Monday - Friday and Saturday every 10th weekend.
*Inpatient or Outpatient Oncology experience highly preferred*
Job Summary: Provide professional pharmaceutical care for Roper St. Francis Healthcare inpatients and outpatients by establishing, practicing, and promoting high standards of quality care.
Minimum Qualifications:
Education: Graduate of an accredited A.C.P.E. College of Pharmacy; Pharm. D. Degree preferred. In lieu of a Pharm. D. degree, at least 5 years of Clinical Pharmacy experience required.
Experience: Previous hospital experience or suitable hospital experience during pharmacy education or internship is required. Pharmacy Practice Residency (or equivalent) preferred.
Licensure/Certification: Licensed by the Board of Pharmacy to practice the profession of pharmacy in South Carolina.
Primary Source Verification: Yes– http://www.llr.state.sc.us/
Knowledge/Skills: Knowledge of professional pharmacy practices. Knowledge of hospital pharmacy medication distribution systems. Possesses skills necessary to monitor medication therapies in relation to the age of the patient to include pediatrics, adolescents, adults, and geriatrics. Skill in reading and interpreting the English language. Skill in identifying problems and recommending solutions. Skill in establishing and maintaining an effective working relationship with patients, hospital/medical staff, and the public. Ability to interpret, adapt, and apply guidelines and procedures. Ability to communicate clearly. Must be able to effectively supervise pharmacy supportive personnel.
Other: Requires prolonged standing or sitting. Requires frequent bending, stooping, or stretching. May requires lifting up to 50 pounds. Requires eye-hand coordination and manual dexterity. Requires the ability to distinguish letters and symbols. Requires normal vision range. Requires working under stressful conditions and working irregular hours.
Contacts: Constant interaction with patients, family members, physicians, nurses, and other ancillary personnel.
Work Demands/Environment:
Work is performed in the patient care areas, decentralized and main pharmacies. Frequent standing, walking, sitting, bending, stooping. May require lifting or moving items up to 25 lbs. Frequent use of finger/hand dexterity and eye/hand coordination. Frequent reaching with hands/arms. Corrected hearing and vision to normal range. Requires visual acuity and normal color perception needed. Minimal risk of exposure to blood, body fluids or tissue. Possible exposure to infectious materials, communicable diseases and/or other conditions common to a healthcare environment. Possible exposure to toxic substances and pharmaceutical preparations. Ability to read and comprehend. Fast paced, high traffic work environment which may be interruptive and stressful. May be required to take call and/or work weekends/holidays based on the needs of the department. Requires the use of office equipment, such as computer terminals, personal computers, and telephones.
As a Roper St. Francis Healthcare teammate, you're part of a Mission that matters. We support your well-being—personally and professionally. Our benefits are built to grow with you and meet your unique needs, every step of the way.
What we offer
- Competitive pay, incentives, referral bonuses and 403(b) with employer contributions (when eligible)
- Medical, dental, vision, prescription coverage, HSA/FSA options, life insurance, mental health resources and discounts
- Paid time off, parental and FMLA leave, short- and long-term disability
- Tuition assistance, professional development and continuing education support
Benefits may vary based on the market and employment status
Roper St. Francis Healthcare is an equal opportunity employer.
It is our policy to abide by all Federal and State laws, as well as, the requirements of 41 CFR 60-1.4(a), 60-300.5(a) and 60-741.5(a).Accordingly, all applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, sexual orientation, gender identity, age, genetic information, or protected veteran status, and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact The Talent Acquisition Team at recruitment@RSFH.com
See All 18 Clinical Pharmacist Jobs in South Carolina
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Find Clinical Pharmacist JobsClinical Pharmacist Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Clinical Pharmacist Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in clinical pharmacist jobs across South Carolina.
- Active South Carolina pharmacist license issued by the South Carolina Board of Pharmacy
- Doctor of Pharmacy degree from an ACPE-accredited school of pharmacy
- Completion of a PGY1 pharmacy practice residency or equivalent clinical experience
- Board certification such as BCPS, BCOP, or relevant specialty credential preferred
- Proficiency with electronic health record systems, particularly Epic or Cerner
- Strong clinical documentation skills and ability to participate in interdisciplinary care teams
Clinical Pharmacist Jobs in South Carolina: Frequently Asked Questions
How do you become a clinical pharmacist in South Carolina?
You must hold an active pharmacist license from the South Carolina Board of Pharmacy, which requires graduating from an ACPE-accredited Doctor of Pharmacy program and passing the NAPLEX and MPJE licensing exams. Most clinical pharmacist roles in South Carolina also expect completion of at least a PGY1 residency. Candidates pursuing specialty positions in areas like oncology or cardiology typically complete a PGY2 residency and obtain board certification before applying.
How much do clinical pharmacists make in South Carolina?
Clinical pharmacists in South Carolina earn a median of about $135,700 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $82,430 for the lowest 10% to over $170,270 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinical pharmacists in South Carolina?
South Carolina clinical pharmacist roles are posted by McLeod Health, Prisma Health, and Beaufort Memorial Hospital and others right now, based on current listings on Migrate Mate as of October 2026. South Carolina's largest health systems, including Prisma Health and MUSC Health, maintain some of the most consistent clinical pharmacist pipelines in the state year-round.
Which South Carolina cities have the most clinical pharmacist jobs?
Rock Hill, Greenville, and Bluffton lead South Carolina in clinical pharmacist openings. Columbia anchors the market as the state capital and home to Prisma Health and several regional hospital campuses, while Greenville's expanding health corridor and Charleston's academic medical center activity at MUSC Health drive hiring in those metros.
How can I get hired as a clinical pharmacist in South Carolina with little or no experience?
The most realistic entry path is completing a PGY1 residency at a South Carolina health system, with Prisma Health and MUSC Health both running accredited programs that frequently convert residents to staff clinical pharmacists. New graduates without residency experience can target staff pharmacist roles at community hospitals or outpatient infusion centers as a bridge. Holding an active South Carolina Board of Pharmacy license and any ACPE certificate program in a specialty gives early-career candidates a clear edge over unlicensed applicants.
Where can I find and apply to clinical pharmacist jobs in South Carolina?
You can find and apply to clinical pharmacist jobs in South Carolina on Migrate Mate, which lists current openings across the state. Search the available roles, find the ones that match your experience and the part of South Carolina you want to work in, and apply directly to the positions that fit.
See All 18 Clinical Pharmacist Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Clinical Pharmacist Jobs