Commercial Director Jobs in Massachusetts
Commercial Director jobs in Massachusetts are open across Boston, Waltham, and Cambridge and other Massachusetts metros, with employers like Danaher Corporation, Xenon Pharmaceuticals, and Alvarez & Marsal hiring at every experience level. Find a role that fits below and apply directly.
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Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
- Physical and Emotional Wellness
- Financial Wellness
- Support for Caregivers
For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
The Importance of the Role
The Associate Director, Commercial Business Performance & Insights will play a critical role in helping Sarepta understand how its in-market products are performing and where leadership attention is needed. This person will be responsible for turning complex commercial data into clear, accurate, and actionable insights that support decision-making across the Commercial organization.
Today, much of this work is managed through a detailed Excel-based reporting process. This role will help modernize that approach by partnering with Commercial Analytics, IT, and business stakeholders to move toward more scalable dashboards, automated reporting, and repeatable performance views. In doing so, this person will help create a stronger foundation for how Sarepta monitors performance, identifies trends, and responds to opportunities or risks across the business.
This is a highly visible role for someone who enjoys both the detail and the story behind the data. The successful candidate will help ensure leadership is working from accurate information, connect themes across recurring analyses and business reviews, and translate performance signals into practical implications for the organization. The role offers regular exposure to senior commercial leaders and the opportunity to shape how business performance is understood, communicated, and acted upon across Sarepta’s in-market portfolio.
This position resides within the Commercial organization and will report to the Executive Director, Commercial Operations.
The Opportunity to Make a Difference
- Own the weekly, monthly, and quarterly business performance cadence for Sarepta’s in-market products, including recurring CCO updates, monthly stakeholder reviews, quarterly business reviews, and other leadership forums.
- Maintain and continuously improve the core business performance model and reporting infrastructure, ensuring recurring metrics, data inputs, calculations, outputs, and executive-facing materials are accurate, current, and clearly documented.
- Drive the transition from the current Excel-based process to a scalable dashboard/reporting environment by defining business requirements, designing the reporting views and logic, validating outputs, and ensuring the final tools meet the needs of Commercial leadership, in partnership with Commercial Analytics, IT, and cross-functional business owners.
- Maintain a consistent set of recurring commercial metrics and analyses, including patient flow, treatment progression, and other measures of commercial execution.
- Monitor performance trends across patient-level, site-level, field, payer, and operational data to identify emerging risks, opportunities, data anomalies, and areas requiring leadership attention.
- Translate data into clear business implications by connecting themes across recurring analyses, stakeholder discussions, and leadership forums.
- Partner with Sales, Marketing, Market Access, Patient Services, Finance, Commercial Analytics, IT, and other cross-functional teams to resolve data issues, align on performance insights, and support action planning.
- Prepare executive-ready performance updates, slide materials, and select Board or leadership readouts related to commercial performance.
- Conduct ad hoc analyses and performance deep dives to answer priority business questions and support strategic decision-making across the Commercial organization.
- Provide analytical rigor and critical thinking to commercial decision-making, ensuring leadership discussions are grounded in accurate, defensible data.
- Other related duties as required.
More about You
- Bachelor’s degree required with 10+ years of experience; Master's preferred with 8+ years of experience.
- 8-10 years of experience in biopharma commercial analytics, commercial operations, business insights, finance, or strategy consulting; rare disease, gene therapy, or specialty market experience preferred.
- Strong analytical skills, including the ability to work with complex data, identify trends, investigate variances, and synthesize findings into clear business implications.
- Ability to translate detailed analyses into concise, executive-ready presentations and recommendations.
- Advanced Excel and PowerPoint skills required; experience with Tableau, Power BI, or similar visualization tools preferred.
- Strong attention to detail and sound judgment, including the ability to assess whether data is accurate, complete, and appropriate for leadership use.
- Excellent communication skills, with the ability to explain analytical findings clearly to senior leaders and cross-functional partners.
- Ability to work independently, manage multiple priorities, and operate effectively in a fast-paced, complex environment.
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
LOCATION
This position requires work on site at one of Sarepta’s facilities in the United States.
COMPENSATION
- Salary Range: $160,800 - $201,000 per year.
Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
See All 27 Commercial Director Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Commercial Director JobsCommercial Director Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Commercial Director Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Danaher Corporation5

- Xenon Pharmaceuticals3

- Alvarez & Marsal2

- ProcDNA2

- Sarepta Therapeutics2

Top Industries Hiring
- Biotechnology & Pharmaceuticals15
- Healthcare & Medical Services5
- Medical Devices4
- Consulting & Professional Services3
- Technology & Software3
What Massachusetts Employers Look For
The qualifications that appear most often in commercial director jobs across Massachusetts.
- Proven experience leading enterprise sales or revenue teams at a senior level
- Demonstrated ability to build and execute go-to-market strategies
- Experience managing P&L or commercial budgets
- Strong background in CRM platforms such as Salesforce
- Bachelor's degree in business, economics, or a related field
- Experience structuring and negotiating complex, multi-stakeholder contracts
Commercial Director Jobs in Massachusetts: Frequently Asked Questions
How many commercial director jobs are there in Massachusetts?
There are 27+ commercial director openings in Massachusetts on Migrate Mate as of June 2026, with the most roles in Boston, Waltham, and Cambridge. New positions post regularly as employers across Massachusetts hire.
Which Massachusetts cities have the most commercial director jobs?
Boston, Waltham, and Cambridge have the most commercial director openings in Massachusetts right now, with additional roles spread across smaller metros statewide.
Which companies hire commercial directors in Massachusetts?
Employers hiring commercial directors in Massachusetts include Danaher Corporation, Xenon Pharmaceuticals, and Alvarez & Marsal, based on current listings on Migrate Mate as of June 2026.
Are there remote commercial director jobs in Massachusetts?
Yes. About 37% of commercial director openings tied to Massachusetts are remote or hybrid as of June 2026. The rest are on-site roles based in Massachusetts metros.
How do I apply for commercial director jobs in Massachusetts?
You can apply to commercial director jobs in Massachusetts directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Massachusetts location, then apply to each one that fits.
See All 27 Commercial Director Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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