Nurse Practitioner Jobs in Mississippi

Nurse Practitioner jobs in Mississippi are concentrated in Jackson, Gulfport, and Hattiesburg, where large health systems and federally qualified health centers drive consistent hiring across primary care, family practice, and behavioral health. Major employers with a lasting footprint in the state include University of Mississippi Medical Center, Singing River Health System, and Forrest Health. Demand runs from new graduates entering rural health clinics under collaborative practice agreements to seasoned NPs leading outpatient specialty practices. Find a role that fits below and apply directly.

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Overview

Open roles32
Top employerOptum
Top cityJackson, MS
Cities hiring24
Work type80% On-site
Top industryInsurance

Showing 5 of 32+ Nurse Practitioner jobs

Advanced Practice Nurse - Family Nurse Practitioner
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Advanced Practice Nurse - Family Nurse Practitioner
US Department of Veterans Affairs
Biloxi, Mississippi
Consulting & Professional Services
Project & Program Management
Project Management
$128k - $186k/yr
On-Site
Post-Master's Certificate (Nursing)
10,000+

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Nurse Practitioner - Greenwood/Cleveland Neurology Clinic
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Added 1d ago
Nurse Practitioner - Greenwood/Cleveland Neurology Clinic
FMOL Health
Greenwood, Mississippi
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
BLS Certification
10,000+

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Nurse Practitioner
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Added 1d ago
Nurse Practitioner
Singing River Health System
Pascagoula, Mississippi
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
1,001-5,000

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Palliative Nurse Practitioner
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Added 1d ago
Palliative Nurse Practitioner
VitalCaring Group
Madison, Mississippi
Healthcare Administration
Nursing
Patient Services & Wellbeing
Doctoral degree
1,001-5,000

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Advanced Practice Nurse (Nurse Practitioner) - Community Care
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Added 3d ago
Advanced Practice Nurse (Nurse Practitioner) - Community Care
US Department of Veterans Affairs
Jackson, Mississippi
IT Support
Project Management
Technical Program Management
$119k - $173k/yr
On-Site
Acute Care Nurse Practitioner Certification - Adult Gerontology
10,000+

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See All 32 Nurse Practitioner Jobs in Mississippi

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Nurse Practitioner Jobs by City in Mississippi

Where Mississippi roles are concentrated, by current openings.

Jackson
3 jobs
Madison
3 jobs
Gulfport
3 jobs
Pascagoula
2 jobs
Hattiesburg
2 jobs
Enid
1 job
Walls
1 job
Biloxi
1 job
Canton
1 job

Nurse Practitioner Job Market in Mississippi

A snapshot from current Mississippi openings, updated as new roles post.

Who's Hiring

Optum3 open roles
Baptist Memorial Health Care2 open roles
US Department of Veterans Affairs2 open roles

Top Industries Hiring

  • Insurance

What Mississippi Employers Look For

The qualifications that appear most often in nurse practitioner jobs across Mississippi.

  • Active Mississippi Advanced Practice Registered Nurse license or a multistate compact license recognized in Mississippi
  • National board certification from AANP or ANCC in a relevant nurse practitioner specialty
  • Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
  • Current, unencumbered registered nurse license as required for APRN designation in Mississippi
  • Ability to practice under a collaborative practice agreement with a Mississippi-licensed physician
  • Current BLS and ACLS certification from the American Heart Association

Nurse Practitioner Jobs in Mississippi: Frequently Asked Questions

How do you become a nurse practitioner in Mississippi?

To become a nurse practitioner in Mississippi, you must hold an active registered nurse license and complete a graduate-level nurse practitioner program accredited by CCNE or ACEN. After graduating, you sit for national board certification through AANP or ANCC in your chosen specialty. You then apply to the Mississippi Board of Nursing for Advanced Practice Registered Nurse designation. Mississippi also requires a collaborative practice agreement with a supervising physician before you can see patients independently.

How much do nurse practitioners make in Mississippi?

Nurse practitioners in Mississippi earn a median of about $124,730 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $98,780 for the lowest 10% to over $156,830 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire nurse practitioners in Mississippi?

Employers hiring nurse practitioners in Mississippi right now include Optum, Baptist Memorial Health Care, and US Department of Veterans Affairs, based on current listings on Migrate Mate as of October 2026. Mississippi's mix of large academic medical centers, rural health networks, and federally qualified community health centers means hiring is spread well beyond Jackson into smaller counties with ongoing access-to-care needs.

Which Mississippi cities have the most nurse practitioner jobs?

Jackson, Madison, and Gulfport have the most nurse practitioner openings in Mississippi. Jackson leads because it is home to the state's largest academic medical center and a dense cluster of specialty practices, while Gulfport and Hattiesburg anchor the Gulf Coast and Pine Belt markets respectively, each supported by regional hospital systems and a growing outpatient care infrastructure.

Are there remote nurse practitioner jobs in Mississippi?

Yes, but they're rare. About 20% of nurse practitioner openings tied to Mississippi are remote or hybrid as of October 2026, reflecting the hands-on, patient-facing nature of most NP roles. The positions most likely to offer remote or telehealth schedules are in behavioral health, psychiatric-mental health, and chronic disease management, where established telehealth platforms have created genuine part-time or fully remote opportunities.

How can I get hired as a nurse practitioner in Mississippi with little or no experience?

The most realistic entry path is applying to new-graduate NP residency or fellowship programs, which University of Mississippi Medical Center and some larger Forrest Health facilities offer to bridge clinical training into independent practice. Candidates who have worked as RNs in a relevant unit, such as primary care, urgent care, or behavioral health, have a measurable edge when transitioning into NP roles at the same employer. Completing a collaborative practice agreement with a rural clinic or federally qualified health center in an underserved Mississippi county is another concrete route, as workforce shortages in those settings make new NPs more competitive than in saturated metro markets.

Where can I find and apply to nurse practitioner jobs in Mississippi?

You can find and apply to nurse practitioner jobs in Mississippi on Migrate Mate, which lists current Mississippi openings across health systems, clinics, and specialty practices. Find roles that fit your specialty and location and apply directly to the employer through each listing.

See All 32 Nurse Practitioner Jobs in Mississippi

Find roles in Mississippi that match your experience and apply in just a few clicks.

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