Nurse Practitioner Or Physician Assistant Jobs in South Dakota
Nurse Practitioner Or Physician Assistant jobs in South Dakota concentrate heavily in primary care, rural health, and hospital-based medicine, with demand running from new graduates to experienced clinicians managing independent panels. The most active hiring is in Sioux Falls, Rapid City, and Aberdeen, where systems like Sanford Health, Monument Health, and Avera Health anchor the market with consistent openings year-round. Family medicine, urgent care, and surgical assistance are the specialties drawing the most consistent postings statewide. See the openings below and apply to the ones that match your experience.
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Showing 5 of 28+ Nurse Practitioner Or Physician Assistant jobs
Careers With Purpose
Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Facility: Black Hills Haines Urg Care
Location: Rapid City, SD
Address: 1730 Haines Ave, Rapid City, SD 57701, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 40.00
Job Summary
The Occupational Medicine Nurse Practitioner provides advanced nursing care focused on the prevention, evaluation, treatment, and management of work-related injuries and illnesses. The NP works in collaboration with physicians, employers, safety personnel, and healthcare providers to promote employee health, ensure regulatory compliance, and support safe return-to-work strategies. Evaluate, diagnose, and treat work-related injuries and illnesses in accordance with occupational health standards and regulatory guidelines.
Conduct pre-employment, periodic, and return-to-work physical examinations.
Perform functional capacity evaluations (FCEs), drug and alcohol testing, TB screenings, immunizations, and other health surveillance exams.
Collaborate with employers to support workers' compensation claims and return-to-work planning.
Educate patients on injury prevention, ergonomics, safe work practices, and chronic disease management.
Maintain detailed documentation in compliance with OSHA, DOT, and state/federal guidelines.
Communicate with case managers, safety officers, and HR departments to coordinate employee care.
Participate in wellness and health promotion programs tailored to the workplace.
Assist in the development of occupational health protocols and policies.
Ensure timely and appropriate referral to specialty care as needed.
Qualifications
Master’s or Doctorate degree from an accredited Nurse Practitioner program.
If APRN was licensed prior to August 1, 1995, master's degree in nursing is preferred.
Experience in occupational medicine, urgent care, emergency medicine, or internal medicine preferred.
Current licensure as a Registered Nurse and Nurse Practitioner in each state of practice.
Current Drug Enforcement Administration (DEA) permit to prescribe controlled substances in each state of practice.
State Controlled Substance License (if required by State)
National board certification as a Family (FNP-BC) or (FNP–C), Adult-Gerontology Primary Care (AGPCNP-BC) or (A-GNP), Adult (ANP-C).
Obtains and subsequently maintains required specific competencies and certifications as outlined on privilege form.
Privileging documents and related credentialing requirements will supersede this job description in defining minimum qualifications, criteria, and scope of practice, if variation between documents exists.
Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits .
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org .
Sanford has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Req Number: R-0272511
Job Function: Advanced Practice Provider
Featured: No
Visas Accepted: N/A
Careers With Purpose
Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Facility: Black Hills Haines Urg Care
Location: Rapid City, SD
Address: 1730 Haines Ave, Rapid City, SD 57701, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 40.00
Job Summary
The Occupational Medicine Nurse Practitioner provides advanced nursing care focused on the prevention, evaluation, treatment, and management of work-related injuries and illnesses. The NP works in collaboration with physicians, employers, safety personnel, and healthcare providers to promote employee health, ensure regulatory compliance, and support safe return-to-work strategies. Evaluate, diagnose, and treat work-related injuries and illnesses in accordance with occupational health standards and regulatory guidelines.
Conduct pre-employment, periodic, and return-to-work physical examinations.
Perform functional capacity evaluations (FCEs), drug and alcohol testing, TB screenings, immunizations, and other health surveillance exams.
Collaborate with employers to support workers' compensation claims and return-to-work planning.
Educate patients on injury prevention, ergonomics, safe work practices, and chronic disease management.
Maintain detailed documentation in compliance with OSHA, DOT, and state/federal guidelines.
Communicate with case managers, safety officers, and HR departments to coordinate employee care.
Participate in wellness and health promotion programs tailored to the workplace.
Assist in the development of occupational health protocols and policies.
Ensure timely and appropriate referral to specialty care as needed.
Qualifications
Master’s or Doctorate degree from an accredited Nurse Practitioner program.
If APRN was licensed prior to August 1, 1995, master's degree in nursing is preferred.
Experience in occupational medicine, urgent care, emergency medicine, or internal medicine preferred.
Current licensure as a Registered Nurse and Nurse Practitioner in each state of practice.
Current Drug Enforcement Administration (DEA) permit to prescribe controlled substances in each state of practice.
State Controlled Substance License (if required by State)
National board certification as a Family (FNP-BC) or (FNP–C), Adult-Gerontology Primary Care (AGPCNP-BC) or (A-GNP), Adult (ANP-C).
Obtains and subsequently maintains required specific competencies and certifications as outlined on privilege form.
Privileging documents and related credentialing requirements will supersede this job description in defining minimum qualifications, criteria, and scope of practice, if variation between documents exists.
Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits .
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org .
Sanford has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Req Number: R-0272511
Job Function: Advanced Practice Provider
Featured: No
Visas Accepted: N/A
See All 28 Nurse Practitioner Or Physician Assistant Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
Find JobsNurse Practitioner Or Physician Assistant Jobs by City in South Dakota
Where South Dakota roles are concentrated, by current openings.
Nurse Practitioner Or Physician Assistant Job Market in South Dakota
A snapshot from current South Dakota openings, updated as new roles post.
Who's Hiring
- Sanford Health13
- Avera Health9
- Lyra Health1
- Horizon Health1
- Sioux Center Health1
Top Industries Hiring
- Healthcare & Medical Services
- Non-Profit & Social Services
What South Dakota Employers Look For
The qualifications that appear most often in nurse practitioner or physician assistant jobs across South Dakota.
- Active South Dakota nurse practitioner or physician assistant license issued by the South Dakota Board of Medical Examiners
- Master of Science in Nursing, Doctor of Nursing Practice, or accredited physician assistant master's degree required
- National certification from AANP, ANCC, or NCCPA required prior to start date
- Current DEA registration or eligibility to obtain South Dakota controlled substance prescribing authority
- Two or more years of clinical experience in a primary care, urgent care, or specialty setting preferred
- BLS and ACLS certification required, with ATLS preferred for surgical and emergency positions
Nurse Practitioner Or Physician Assistant Jobs in South Dakota: Frequently Asked Questions
How do you become a nurse practitioner or physician assistant in South Dakota?
Both roles require state licensure through the South Dakota Board of Medical Examiners. Nurse practitioners must hold an accredited graduate-level nursing degree and a national certification such as the AANP or ANCC credential before applying for licensure. Physician assistants must graduate from an accredited PA program and pass the PANCE exam. South Dakota participates in the Nurse Licensure Compact, so RNs with a multistate license may hold NP licensure here once the graduate credential is met.
Which companies hire nurse practitioner or physician assistants in South Dakota?
Companies currently hiring nurse practitioner or physician assistants in South Dakota include Sanford Health, Avera Health, and Lyra Health, per current listings on Migrate Mate as of August 2026. Sanford Health, Avera Health, and Monument Health are the dominant long-term employers in the state, operating clinics and hospital campuses across Sioux Falls, Rapid City, and smaller rural communities where advanced practice providers often serve as the primary point of care.
Which South Dakota cities have the most nurse practitioner or physician assistant jobs?
The cities with the most nurse practitioner or physician assistant openings in South Dakota are Sioux Falls, Pierre, and Rapid City. Sioux Falls drives the largest share of postings as the state's most populous city and home to both Sanford Health and Avera Health's flagship campuses, while Rapid City's volume reflects Monument Health's regional hospital and clinic network serving the western half of the state.
Are there remote nurse practitioner or physician assistant jobs in South Dakota?
Yes, but they're rare. Nurse practitioner and physician assistant roles are inherently hands-on and typically require an in-person patient relationship, which limits remote options significantly. About 20% of nurse practitioner or physician assistant openings tied to South Dakota are remote or hybrid as of August 2026, and those positions tend to be in telehealth primary care, chronic disease management, or utilization review rather than procedural or acute care specialties.
How can I get hired as a nurse practitioner or physician assistant in South Dakota with little or no experience?
The most realistic entry path is a new-graduate or transition-to-practice residency program, and both Sanford Health and Avera Health run structured advanced practice provider onboarding tracks designed for clinicians completing their first year post-licensure. Candidates who hold a South Dakota or compact license and are already certified should apply to family medicine and urgent care openings first, as those settings offer the broadest supervision support. Highlighting clinical rotations completed at South Dakota sites and rural health experience strengthens any application significantly.
Where can I find and apply to nurse practitioner or physician assistant jobs in South Dakota?
You can find and apply to nurse practitioner or physician assistant jobs in South Dakota on Migrate Mate, which lists current openings tied to South Dakota employers and locations. Search the listings to find roles that match your specialty, experience level, and preferred location, then apply directly to the positions that fit. No signup is required to see the openings.
See All 28 Nurse Practitioner Or Physician Assistant Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
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