Oncology Registered Nurse Jobs in Missouri

Oncology Registered Nurse jobs in Missouri are among the most consistently in-demand nursing roles in the state, concentrated in academic medical centers, comprehensive cancer programs, and large hospital systems across St. Louis, Kansas City, and Springfield. Major employers with a lasting presence include BJC HealthCare, University of Missouri Health Care, and Saint Luke's Health System. The most sought-after specialties are infusion nursing, bone marrow transplant, and radiation oncology support. Find a role that fits below and apply directly.

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Overview

Open roles30
Top employerMercy
Top cityKansas City, MO
Cities hiring12
Work type50% On-site
Top industryHealthcare

Showing 4 of 30+ Oncology Registered Nurse jobs

Washington University in St. Louis
RN Clinical Nurse Coordinator (Hybrid) - Medical Oncology
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Washington University in St. Louis
Added 1d ago
RN Clinical Nurse Coordinator (Hybrid) - Medical Oncology
Washington University in St. Louis
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
$65k - $110k/yr
Hybrid
BLS Certification
10,000+

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Centerpoint Medical Center
RN Manager Med Surg Oncology
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Centerpoint Medical Center
Added 1d ago
RN Manager Med Surg Oncology
Centerpoint Medical Center
Independence, Missouri
Healthcare Administration
Patient Services & Wellbeing
Physicians

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Jefferson City Medical Group
Registered Nurse Navigator - Oncology
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Jefferson City Medical Group
Added 6d ago
Registered Nurse Navigator - Oncology
Jefferson City Medical Group
Jefferson City, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
Bachelor of Science in Nursing
501-1,000

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Mosaic Life Care
Advanced Practice Registered Nurse - Medical Oncology
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Mosaic Life Care
Added 3w ago
Advanced Practice Registered Nurse - Medical Oncology
Mosaic Life Care
Saint Joseph, Missouri
Healthcare Administration
Patient Services & Wellbeing
Physicians
Master's degree in nursing
1,001-5,000

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Oncology Registered Nurse Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

Kansas City
6 jobs
St. Louis
5 jobs
Saint Joseph
3 jobs
Cape Girardeau
3 jobs
Branson
2 jobs
Liberty
2 jobs
Columbia
2 jobs
Chesterfield
2 jobs
Fenton
1 job

Oncology Registered Nurse Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Mercy
Mercy5 open roles
Mosaic Life Care
Mosaic Life Care4 open roles
Washington University in St. Louis
Washington University in St. Louis4 open roles

Top Industries Hiring

  • Healthcare & Medical Services
  • Education

What Missouri Employers Look For

The qualifications that appear most often in oncology registered nurse jobs across Missouri.

  • Active registered nurse license issued or recognized by the Missouri State Board of Nursing
  • Associate or bachelor's degree in nursing from an accredited program
  • Current BLS and ONS chemotherapy and biotherapy administration certification
  • Minimum one to two years of oncology or medical-surgical acute care experience
  • Familiarity with electronic health records systems such as Epic or Cerner
  • Strong knowledge of symptom management, cancer treatment protocols, and patient education

Oncology Registered Nurse Jobs in Missouri: Frequently Asked Questions

How do you become a oncology registered nurse in Missouri?

You become an oncology registered nurse in Missouri by first completing an accredited associate or bachelor's degree in nursing, then passing the NCLEX-RN exam and applying for licensure through the Missouri State Board of Nursing. Missouri participates in the Nurse Licensure Compact, so nurses licensed in other compact states may practice without a separate Missouri license. Most employers then require or encourage the Oncology Certified Nurse credential, earned through the Oncology Nursing Certification Corporation after gaining clinical oncology experience.

How much do oncology registered nurses make in Missouri?

Oncology registered nurses in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire oncology registered nurses in Missouri?

Employers hiring oncology registered nurses in Missouri right now include Mercy, Mosaic Life Care, and Washington University in St. Louis, based on current listings on Migrate Mate as of August 2026. Missouri's large integrated health systems and NCI-designated cancer programs drive consistent demand for oncology nursing staff across inpatient, outpatient infusion, and ambulatory care settings.

Which Missouri cities have the most oncology registered nurse jobs?

The Missouri cities with the most oncology registered nurse openings are Kansas City, St. Louis, and Saint Joseph. St. Louis leads because of its concentration of academic medical centers and the Siteman Cancer Center network, Kansas City follows with major systems including University of Kansas Health System on the state border and Saint Luke's anchoring the metro, and Springfield draws steady openings through Mercy and CoxHealth serving the broader Ozarks region.

Are there remote oncology registered nurse jobs in Missouri?

Yes, but they're rare. Oncology nursing is primarily a hands-on clinical role requiring direct patient contact for chemotherapy administration, assessment, and symptom management. About 50% of oncology registered nurse openings tied to Missouri are remote or hybrid as of August 2026, and those positions are typically limited to telephonic triage nursing, care coordination, or utilization review roles that don't require bedside duties.

How can I get hired as a oncology registered nurse in Missouri with little or no experience?

The most realistic entry path is applying to a new graduate nurse residency program at a large Missouri health system, as BJC HealthCare, University of Missouri Health Care, and Mercy all run structured residencies that place new RNs into oncology or medical-surgical units where oncology patients are commonly treated. Gaining experience in med-surg, critical care, or infusion nursing roles first is a common lateral move that opens oncology-specific positions. Completing the ONS chemotherapy certification early and volunteering for oncology patient assignments during residency gives candidates a meaningful edge.

Where can I find and apply to oncology registered nurse jobs in Missouri?

You can find and apply to oncology registered nurse jobs in Missouri on Migrate Mate, which lists current Missouri openings across health systems, cancer centers, and outpatient clinics. Find the roles that fit your experience and credentials and apply directly to the employer.

See All 30 Oncology Registered Nurse Jobs in Missouri

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