Oncology Registered Nurse Jobs in Missouri

Oncology Registered Nurse jobs in Missouri are among the most consistently in-demand nursing roles in the state, concentrated in academic medical centers, comprehensive cancer programs, and large hospital systems across St. Louis, Kansas City, and Springfield. Major employers with a lasting presence include BJC HealthCare, University of Missouri Health Care, and Saint Luke's Health System. The most sought-after specialties are infusion nursing, bone marrow transplant, and radiation oncology support. Find a role that fits below and apply directly.

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Overview

Open roles42
Top employerMercy
Top citySt. Louis, MO
Cities hiring16
Work type50% On-site
Top industryHealthcare

Showing 5 of 42+ Oncology Registered Nurse jobs

Registered Nurse (RN) - Oncology Infusion Center
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Added 1d ago
Registered Nurse (RN) - Oncology Infusion Center
Mercy
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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Registered Nurse - Charge Nurse - Oncology
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Added 3d ago
Registered Nurse - Charge Nurse - Oncology
SSM Health
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Managed Registered Nurses (RNs)
10,000+

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RN Specialty Clinic - Urology Oncology (F/T Days)
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Added 5d ago
RN Specialty Clinic - Urology Oncology (F/T Days)
Mercy
Creve Coeur, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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Clinic RN - Pediatric Oncology (Part Time)
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Added 1w ago
Clinic RN - Pediatric Oncology (Part Time)
Mercy
Springfield, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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RN Weekend 7A Oncology Full Time Nights
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Added 1w ago
RN Weekend 7A Oncology Full Time Nights
Mercy
Springfield, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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Oncology Registered Nurse Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
12 jobs
Rolla
4 jobs
Creve Coeur
3 jobs
Kansas City
3 jobs
Springfield
3 jobs
Saint Joseph
3 jobs
Branson
2 jobs
Chesterfield
2 jobs
Cape Girardeau
2 jobs

Oncology Registered Nurse Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • Mercy12
  • Mosaic Life Care4
  • American Traveler4
  • Washington University in St. Louis4
  • SSM Health3

Top Industries Hiring

  • Healthcare & Medical Services

What Missouri Employers Look For

The qualifications that appear most often in oncology registered nurse jobs across Missouri.

  • Active registered nurse license issued or recognized by the Missouri State Board of Nursing
  • Associate or bachelor's degree in nursing from an accredited program
  • Current BLS and ONS chemotherapy and biotherapy administration certification
  • Minimum one to two years of oncology or medical-surgical acute care experience
  • Familiarity with electronic health records systems such as Epic or Cerner
  • Strong knowledge of symptom management, cancer treatment protocols, and patient education

Oncology Registered Nurse Jobs in Missouri: Frequently Asked Questions

How do you become a oncology registered nurse in Missouri?

You become an oncology registered nurse in Missouri by first completing an accredited associate or bachelor's degree in nursing, then passing the NCLEX-RN exam and applying for licensure through the Missouri State Board of Nursing. Missouri participates in the Nurse Licensure Compact, so nurses licensed in other compact states may practice without a separate Missouri license. Most employers then require or encourage the Oncology Certified Nurse credential, earned through the Oncology Nursing Certification Corporation after gaining clinical oncology experience.

How much do oncology registered nurses make in Missouri?

Oncology registered nurses in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire oncology registered nurses in Missouri?

Employers hiring oncology registered nurses in Missouri right now include Mercy, Mosaic Life Care, and American Traveler, based on current listings on Migrate Mate as of October 2026. Missouri's large integrated health systems and NCI-designated cancer programs drive consistent demand for oncology nursing staff across inpatient, outpatient infusion, and ambulatory care settings.

Which Missouri cities have the most oncology registered nurse jobs?

The Missouri cities with the most oncology registered nurse openings are St. Louis, Rolla, and Creve Coeur. St. Louis leads because of its concentration of academic medical centers and the Siteman Cancer Center network, Kansas City follows with major systems including University of Kansas Health System on the state border and Saint Luke's anchoring the metro, and Springfield draws steady openings through Mercy and CoxHealth serving the broader Ozarks region.

Are there remote oncology registered nurse jobs in Missouri?

Yes, but they're rare. Oncology nursing is primarily a hands-on clinical role requiring direct patient contact for chemotherapy administration, assessment, and symptom management. About 50% of oncology registered nurse openings tied to Missouri are remote or hybrid as of October 2026, and those positions are typically limited to telephonic triage nursing, care coordination, or utilization review roles that don't require bedside duties.

How can I get hired as a oncology registered nurse in Missouri with little or no experience?

The most realistic entry path is applying to a new graduate nurse residency program at a large Missouri health system, as BJC HealthCare, University of Missouri Health Care, and Mercy all run structured residencies that place new RNs into oncology or medical-surgical units where oncology patients are commonly treated. Gaining experience in med-surg, critical care, or infusion nursing roles first is a common lateral move that opens oncology-specific positions. Completing the ONS chemotherapy certification early and volunteering for oncology patient assignments during residency gives candidates a meaningful edge.

Where can I find and apply to oncology registered nurse jobs in Missouri?

You can find and apply to oncology registered nurse jobs in Missouri on Migrate Mate, which lists current Missouri openings across health systems, cancer centers, and outpatient clinics. Find the roles that fit your experience and credentials and apply directly to the employer.

See All 42 Oncology Registered Nurse Jobs in Missouri

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