Project Assistant Jobs in Massachusetts
Project Assistant jobs in Massachusetts are concentrated in Boston, Cambridge, and Worcester, where life sciences companies like Biogen and Thermo Fisher Scientific, and research institutions like Massachusetts General Hospital, maintain steady demand for organized, detail-oriented support staff. The role covers a broad range of specialties in the state, including biotech and clinical trial coordination, higher education administration, and construction and infrastructure project support. Openings appear at every level, from entry-level coordinators working under senior project managers to experienced assistants handling multi-department initiatives. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 69+ Project Assistant jobs
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
Fully knowledgeable of the department/trial(s) protocol requirements, works with a high degree of independence, and contributes to implementing process improvements. By virtue of their experience, expected to provide guidance and mentorship to staff regarding department/trial operations.
Does this position require Patient Care?
No
Essential Functions
- Manage multiple clinical trial sites for the duration of the trial.
- Collect and review essential regulatory documents for completeness before submitting them to Regulatory for final review and/or approval.
- Advise research sites on protocol conduct and interpretation, and ensure the resolution of any issues.
- Evaluate the quality and timeliness of data entry, issue, track, and resolve queries, and implement corrective action plans as needed.
- Maintain a clinical trial database that includes the latest protocol versions and updated contact information.
- Work with the department/trial manager(s) to address issues identified through periodic quality monitoring activities and/or audits.
- Prepare official trial correspondence (i.e., numbered memos). Develop and maintain databases. Generate reports as needed from internal and external databases.
- Assist in the training and development of other junior staff members in key processes and procedures.
- Work with the department/trial manager(s) to address issues identified through periodic quality monitoring activities and/or audits
Qualifications
The Neurological Clinical Research Institute (NCRI), at the Massachusetts General Hospital (MGH) is a premier Academic Research Organization (ARO) managing clinical trials in neurological disorders. The NCRI employs physician clinical researchers, research nurses, project managers, data managers, SAS programmers, systems analysts, grants managers, research nurses,
quality specialists and administrative assistants dedicated to planning and implementing clinical trials.
Works independently in a dynamic, fast-paced environment to ensure that the Research Portfolio workflow is run efficiently and effectively. Has a thorough understanding of the organization and functions of the Research area. Organizes and tracks training and acts as a Protocol Office liaison for the research area. This position is responsible for all accounts payable and
receivable as well as compliance and reconciliation related to the conduct of clinical trials. This position will also manage special projects as required.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
Relevant activities include, but are not limited to the following:
- Responsible for day-to-day operations of the Research Portfolio including coverage throughout the day, as well as vacations
- Provides oversight Technical Staff as primary resource for administrative/clerical issues.
- Responsible for all financial budgets related to Research Study Maintenance.
- Assist in the development and maintenance of clinical trial SOPs.
- Maintain clinical trial database that includes latest protocol versions and updated contact information.
- Design and prepare clinical trial budget amendments pertaining to Research Study Maintenance.
- Track outside invoices and submit journal entries for payment.
- Obtain and maintain study supplies and reagents.
- Maintain, monitor, and renew lab contracts.
- Performs other duties as assigned.
- Complies with all policies and standards
EDUCATION:
Bachelor's Degree
Related Field of Study required
Can this role accept experience in lieu of a degree? Yes
EXPERIENCE:
Previous Industry Clinical Trial experience 2-3 years required and Data Management experience 2-3 years preferred
FISCAL RESPONSIBILITY:
All financial budgets related to Research Study Maintenance.
Design and prepare clinical trial budget amendments pertaining to Research Study Maintenance
Track outside invoices and submit journal entries for payment
Maintain monitor and renew lab contracts
This position can be either hybrid or remote. Must have reliable access to internet. On occasion and at the discretion of the Director of QA the Clinical Trial Assistant Project Manager (Systems use) may be required to be onsite for meetings, sponsor audits or regulatory inspections. Advanced notice will be given.
Additional Job Details (if applicable)
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
Grade
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
Fully knowledgeable of the department/trial(s) protocol requirements, works with a high degree of independence, and contributes to implementing process improvements. By virtue of their experience, expected to provide guidance and mentorship to staff regarding department/trial operations.
Does this position require Patient Care?
No
Essential Functions
- Manage multiple clinical trial sites for the duration of the trial.
- Collect and review essential regulatory documents for completeness before submitting them to Regulatory for final review and/or approval.
- Advise research sites on protocol conduct and interpretation, and ensure the resolution of any issues.
- Evaluate the quality and timeliness of data entry, issue, track, and resolve queries, and implement corrective action plans as needed.
- Maintain a clinical trial database that includes the latest protocol versions and updated contact information.
- Work with the department/trial manager(s) to address issues identified through periodic quality monitoring activities and/or audits.
- Prepare official trial correspondence (i.e., numbered memos). Develop and maintain databases. Generate reports as needed from internal and external databases.
- Assist in the training and development of other junior staff members in key processes and procedures.
- Work with the department/trial manager(s) to address issues identified through periodic quality monitoring activities and/or audits
Qualifications
The Neurological Clinical Research Institute (NCRI), at the Massachusetts General Hospital (MGH) is a premier Academic Research Organization (ARO) managing clinical trials in neurological disorders. The NCRI employs physician clinical researchers, research nurses, project managers, data managers, SAS programmers, systems analysts, grants managers, research nurses,
quality specialists and administrative assistants dedicated to planning and implementing clinical trials.
Works independently in a dynamic, fast-paced environment to ensure that the Research Portfolio workflow is run efficiently and effectively. Has a thorough understanding of the organization and functions of the Research area. Organizes and tracks training and acts as a Protocol Office liaison for the research area. This position is responsible for all accounts payable and
receivable as well as compliance and reconciliation related to the conduct of clinical trials. This position will also manage special projects as required.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
Relevant activities include, but are not limited to the following:
- Responsible for day-to-day operations of the Research Portfolio including coverage throughout the day, as well as vacations
- Provides oversight Technical Staff as primary resource for administrative/clerical issues.
- Responsible for all financial budgets related to Research Study Maintenance.
- Assist in the development and maintenance of clinical trial SOPs.
- Maintain clinical trial database that includes latest protocol versions and updated contact information.
- Design and prepare clinical trial budget amendments pertaining to Research Study Maintenance.
- Track outside invoices and submit journal entries for payment.
- Obtain and maintain study supplies and reagents.
- Maintain, monitor, and renew lab contracts.
- Performs other duties as assigned.
- Complies with all policies and standards
EDUCATION:
Bachelor's Degree
Related Field of Study required
Can this role accept experience in lieu of a degree? Yes
EXPERIENCE:
Previous Industry Clinical Trial experience 2-3 years required and Data Management experience 2-3 years preferred
FISCAL RESPONSIBILITY:
All financial budgets related to Research Study Maintenance.
Design and prepare clinical trial budget amendments pertaining to Research Study Maintenance
Track outside invoices and submit journal entries for payment
Maintain monitor and renew lab contracts
This position can be either hybrid or remote. Must have reliable access to internet. On occasion and at the discretion of the Director of QA the Clinical Trial Assistant Project Manager (Systems use) may be required to be onsite for meetings, sponsor audits or regulatory inspections. Advanced notice will be given.
Additional Job Details (if applicable)
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
Grade
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
See All 69 Project Assistant Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Project Assistant JobsProject Assistant Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Project Assistant Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Staffing & Recruiting
- Consulting & Professional Services
- Construction & Real Estate
- Electronics & Hardware
What Massachusetts Employers Look For
The qualifications that appear most often in project assistant jobs across Massachusetts.
- Associate's or bachelor's degree in business, communications, or a related field
- Proficiency with Microsoft Office Suite, especially Excel and project scheduling tools
- Experience supporting project timelines, budgets, and stakeholder communications
- Familiarity with project management software such as Asana, Smartsheet, or MS Project
- Strong written and verbal communication skills in a professional setting
- Ability to manage multiple priorities simultaneously and meet deadlines consistently
Project Assistant Jobs in Massachusetts: Frequently Asked Questions
How do you become a project assistant in Massachusetts?
Most project assistant roles in Massachusetts are accessible with an associate's or bachelor's degree in business administration, communications, or a field related to the target industry. No state-issued license is required for the general role, but candidates working in regulated industries like healthcare or construction may benefit from sector-specific credentials such as a Certified Associate in Project Management designation. Massachusetts employers in biotech and higher education often prefer candidates with internship or co-op experience gained through programs at local universities.
Which companies hire project assistants in Massachusetts?
Massachusetts project assistant roles are posted by Jobot, Harvard University, and Consigli Construction and others right now, based on current listings on Migrate Mate as of October 2026. Massachusetts's dense concentration of life sciences firms, research hospitals, and technology companies means project assistant openings appear across a wider variety of industries here than in most other states.
Which Massachusetts cities have the most project assistant jobs?
Boston, Waltham, and Cambridge have the most project assistant openings in Massachusetts. Boston drives the largest share through its concentration of healthcare systems, financial services firms, and universities, while Cambridge's biotech and research corridor generates consistent demand, and Worcester's growing healthcare and manufacturing base supports a steady volume of openings outside the immediate metro.
Are there remote project assistant jobs in Massachusetts?
Yes, and they're more common than in many comparable roles. About 45% of project assistant openings tied to Massachusetts are remote or hybrid as of October 2026, reflecting how much of the work involves scheduling, documentation, and communication rather than on-site presence. Administrative and coordination-heavy positions in technology and professional services firms are the most likely to offer fully remote arrangements.
How can I get hired as a project assistant in Massachusetts with little or no experience?
The most realistic entry path is through an administrative coordinator or departmental assistant role at a large Massachusetts institution, then moving laterally once you have documented project support experience. Hospitals like Brigham and Women's and employers like MIT and Boston University regularly hire entry-level administrative staff who support project-oriented teams. A completed internship, a Certified Associate in Project Management credential, or a portfolio of volunteer-led initiatives can make a candidate from that pool stand out to hiring managers.
Where can I find and apply to project assistant jobs in Massachusetts?
You can find and apply to project assistant jobs in Massachusetts on Migrate Mate, which lists current openings across the state. Search the listings to find roles that match your experience and the industry you want to work in, then apply directly to the ones that fit your background.
See All 69 Project Assistant Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Project Assistant Jobs