Registered Nurse Case Manager Jobs in South Carolina

Registered Nurse Case Manager jobs in South Carolina are open across Little River, Cayce, and Charleston and other South Carolina metros, with employers like McLeod Health, Prisma Health, and FAMILY HOSPICE hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles12+
Top employerMcLeod Health
Top cityLittle River, SC
Cities hiring10
Work type92% On-site
Top industryHealthcare

Showing 5 of 12+ Registered Nurse Case Manager jobs

OneWell Health Care
RN Case Manager
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OneWell Health Care
New 5h ago
RN Case Manager
OneWell Health Care
Conway, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
Caregiving & Elderly Support
$37 - $41/hr
On-Site
Bachelor's
1,001-5,000

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McLeod Health
RN Case Manager
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McLeod Health
New 6h ago
RN Case Manager
McLeod Health
Loris, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
Caregiving & Elderly Support
On-Site
None
10,000+

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Prisma Health
Registered Nurse (RN) - Case Manager
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Prisma Health
Added 2d ago
Registered Nurse (RN) - Case Manager
Prisma Health
Sumter, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Bachelor's
10,000+

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McLeod Health
RN Case Manager
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McLeod Health
Added 1w ago
RN Case Manager
McLeod Health
Little River, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
Caregiving & Elderly Support
On-Site
None
10,000+

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FAMILY HOSPICE
RN Case Manager
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FAMILY HOSPICE
Added 1mo ago
RN Case Manager
FAMILY HOSPICE
Greenwood, South Carolina
Nursing
Healthcare Administration
Patient Services & Wellbeing
Caregiving & Elderly Support
On-Site
None

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See All 12 Registered Nurse Case Manager Jobs in South Carolina

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Registered Nurse Case Manager Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Little River
3 jobs
Cayce
1 jobs
Charleston
1 jobs
Columbia
1 jobs
Conway
1 jobs
Greenwood
1 jobs
Loris
1 jobs
Myrtle Beach
1 jobs
Spartanburg
1 jobs

Registered Nurse Case Manager Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • McLeod Health
    McLeod Health5
  • Prisma Health
    Prisma Health2
  • FAMILY HOSPICE
    FAMILY HOSPICE1
  • Lexington Health
    Lexington Health1
  • Medical University of South Carolina
    Medical University of South Carolina1

Top Industries Hiring

  • Healthcare & Medical Services10
  • Government & Public Sector1

What South Carolina Employers Look For

The qualifications that appear most often in registered nurse case manager jobs across South Carolina.

  • Active RN license with at least two years of clinical nursing experience
  • Experience with utilization review, discharge planning, or care transitions
  • Proficiency in electronic health record systems such as Epic or Cerner
  • Knowledge of payer guidelines, Medicare, Medicaid, and managed care criteria
  • Certified Case Manager (CCM) credential or willingness to obtain within a defined period
  • Strong communication skills for interdisciplinary team collaboration and patient advocacy

Registered Nurse Case Manager Jobs in South Carolina: Frequently Asked Questions

How many registered nurse case manager jobs are there in South Carolina?

There are 12+ registered nurse case manager openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Little River, Cayce, and Charleston. New positions post regularly as employers across South Carolina hire.

How much do registered nurse case managers make in South Carolina?

Registered nurse case managers in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.

Which South Carolina cities have the most registered nurse case manager jobs?

Little River, Cayce, and Charleston have the most registered nurse case manager openings in South Carolina right now, with additional roles spread across smaller metros statewide.

Which companies hire registered nurse case managers in South Carolina?

Employers hiring registered nurse case managers in South Carolina include McLeod Health, Prisma Health, and FAMILY HOSPICE, based on current listings on Migrate Mate as of June 2026.

Are there remote registered nurse case manager jobs in South Carolina?

Yes. About 8% of registered nurse case manager openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.

How do I apply for registered nurse case manager jobs in South Carolina?

You can apply to registered nurse case manager jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.

See All 12 Registered Nurse Case Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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