Registered Nurse Case Manager Jobs in South Carolina
Registered Nurse Case Manager jobs in South Carolina are concentrated in Columbia, Greenville, and Charleston, where major health systems like Prisma Health, MUSC Health, and Palmetto Health anchor steady demand for case management professionals. Acute care transitions, behavioral health, and workers' compensation are among the most active specialties, with openings running from entry-level case coordinator roles to senior utilization management positions. South Carolina's aging coastal population and growing inland medical infrastructure keep this one of the more active hiring markets in the Southeast. Find a role that fits below and apply directly.
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Do you have the career opportunities as a Registered Nurse (RN) Case Manager you want with your current employer? We have an exciting opportunity for you to join Grand Strand Medical Center which is part of the nation's leading provider of healthcare services, HCA Healthcare, and located in sunny Myrtle Beach, South Carolina!
Job Summary and Qualifications
The Registered Nurse (RN) Case Manager collaborates with physicians, nurses, patients, families, and interdisciplinary teams to coordinate care, facilitate discharge planning, and promote efficient utilization of healthcare resources. This role serves as a patient advocate, helping to ensure quality outcomes, seamless transitions of care, and compliance with regulatory requirements.
What you will do in this role:
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You will be responsible for coordinating the plan of care for the patient stay, managing the length of stay, ensuring appropriate resource management, while developing a safe appropriate discharge plan.
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You will facilitate the progression and transition of care and identify patients who are at risk for adverse outcomes during the transition from one level of care/setting to another.
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You will perform a comprehensive assessment of psychosocial, medical and discharge needs of patients/family, along with an assessment of resources appropriate and available to them. You will reassess the patient’s clinical condition as indicated.
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You will be responsible for ensuring the post-acute medical needs and level of care are appropriate, in partnership with Social Services.
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You will evaluate progression of care using evidence-based tools and approved criteria (InterQual) throughout the episode of care; escalating progression and transition of care issues.
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You will make appropriate referrals to third-party payer, disease and case management programs for recurring patients and patients with chronic disease states.
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You will act as a liaison through effective and professional communications between and with physicians, patient / family, hospital staff, and outside agencies. You will serve as an advocate for patient's rights, needs and values.
What qualifications you will need:
- Must be a graduate from an accredited school of Nursing: Associate’s Degree in Nursing or higher is required. BSN is highly preferred.
- Must be licensed as a Registered Nurse in the state which you practice and/or hold an active Compact/Multi-State RN license.
- 1-3 years of clinical, hospital nursing experience is required.
- 2 years of experience in Case Management is highly preferred.
- Certification in Case Management or Utilization Review is preferred.
- InterQual experience is preferred.
Grand Strand Medical Center, offers a total rewards package that supports the health, life, career and retirement of our colleagues. The available plans and programs include:
- Comprehensive benefits for medical, prescription drug, dental, vision, behavioral health and telemedicine services
- Wellbeing support, including free counseling and referral services
- Time away from work programs for paid time off, paid family leave, long- and short-term disability coverage and leaves of absence
- Savings and retirement resources, including a 401(k) Plan with a 100% match on 3% to 9% of pay (based on years of service), Employee Stock Purchase Plan, flexible spending accounts, preferred banking partnerships, retirement readiness tools, rollover support and financial wellbeing counseling
- Education support through tuition assistance, student loan assistance, certification support, dependent scholarships and a partnership with Galen College of Nursing
- Additional benefits for fertility and family building, adoption assistance, life insurance, supplemental health protection plans, auto and home insurance, legal counseling, identity theft protection and consumer discounts
Learn more about Employee Benefits
Note: Eligibility for benefits may vary by location.
Grand Strand Medical Center has provided quality healthcare services since 1978, giving patient's access to highly-trained physicians and advanced technology. With more than 40 years of pioneering healthcare, our 300+ bed hospital is one of the region's leading acute care facilities. We offer a range of services for our patients - including the only cardiac surgery program, neurosurgery program, pediatric intensive care unit, Level I trauma center with two free-standing emergency departments, advanced wound care center, breast cancer center and Carolina Forest Imaging Center. We are recognized, for the chest pain, knee and hip replacement, sepsis and stroke by the Joint Commission.
At Grand Strand Health, you'll find that caring extends to our patients, our people and our South Carolina community. We are committed to each other because when we join together, our patients are cared for in the safest and most compassionate way.
HCA Healthcare has been recognized as one of the World’s Most Ethical Companies® by the Ethisphere Institute more than ten times. In recent years, HCA Healthcare spent an estimated $3.7 billion in cost for the delivery of charitable care, uninsured discounts, and other uncompensated expenses.
"Bricks and mortar do not make a hospital. People do."- Dr. Thomas Frist, Sr.
HCA Healthcare Co-Founder
If you are looking for an opportunity that provides satisfaction and personal growth, we encourage you to apply for our RN Case Manager opening. We promptly review all applications. Highly qualified candidates will be contacted for interviews. Unlock the possibilities and apply today!
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
See All 69 Registered Nurse Case Manager Jobs in South Carolina
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Find JobsRegistered Nurse Case Manager Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Registered Nurse Case Manager Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Your Health Organization25

- Crescent Hospice6

- Patriot Healthcare4

- VIA Health Partners3

- United Energy Workers Healthcare3

Top Industries Hiring
- Healthcare & Medical Services
What South Carolina Employers Look For
The qualifications that appear most often in registered nurse case manager jobs across South Carolina.
- Active RN license issued or recognized by the South Carolina Board of Nursing
- Minimum two to three years of clinical nursing experience in an acute or post-acute setting
- Certification in case management such as CCM or ACM preferred or required
- Proficiency with electronic health records and utilization management documentation systems
- Strong knowledge of discharge planning, insurance authorization, and care coordination workflows
- Experience collaborating with interdisciplinary teams including physicians, social workers, and payers
Registered Nurse Case Manager Jobs in South Carolina: Frequently Asked Questions
How do you become a registered nurse case manager in South Carolina?
You start by earning an active RN license through the South Carolina Board of Nursing, which requires passing the NCLEX-RN after completing an accredited nursing program. From there, most employers expect at least two years of clinical experience before moving into case management. Obtaining the Certified Case Manager credential, offered by the Commission for Case Manager Certification, strengthens your candidacy and is required by many South Carolina hospital systems and insurance-based employers.
How much do registered nurse case managers make in South Carolina?
Registered nurse case managers in South Carolina earn a median of about $82,360 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $66,860 for the lowest 10% to over $106,520 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire registered nurse case managers in South Carolina?
South Carolina registered nurse case manager roles are posted by Your Health Organization, Crescent Hospice, and Patriot Healthcare and others right now, based on current listings on Migrate Mate as of August 2026. Health systems, managed care organizations, and insurance carriers operating across the Columbia, Greenville, and Charleston corridors are among the most consistent sources of case management openings in the state.
Which South Carolina cities have the most registered nurse case manager jobs?
Columbia, Rock Hill, and Aiken lead South Carolina for registered nurse case manager openings. Columbia draws the most postings as the state capital and home to several large hospital networks, while Greenville's expanding Upstate health corridor and Charleston's academic medical community at MUSC generate strong and consistent demand across acute, post-acute, and payer-side case management roles.
Are there remote registered nurse case manager jobs in South Carolina?
Yes, but they are less common than in purely desk-based fields because case managers often conduct in-person assessments, care conferences, and facility visits. About 80% of registered nurse case manager openings tied to South Carolina are remote or hybrid as of August 2026, reflecting real but limited flexibility. Telephonic utilization review and insurance-based case management roles are the segments most likely to offer fully remote arrangements.
How can I get hired as a registered nurse case manager in South Carolina with little or no experience?
The most realistic path is starting in a care coordination or utilization review associate role, which large South Carolina systems like Prisma Health and MUSC Health occasionally open to RNs with strong med-surg or discharge planning backgrounds rather than dedicated case management experience. Lateral moves from hospital social work liaison or transitional care nursing positions also create a natural bridge. Earning the CCM credential early, even as a candidate, signals commitment and gives a less-experienced applicant a measurable edge in South Carolina hiring processes.
Where can I find and apply to registered nurse case manager jobs in South Carolina?
You can find and apply to registered nurse case manager jobs in South Carolina on Migrate Mate, which lists current South Carolina openings updated in real time. Search through the roles available, find the ones that fit your experience and preferred location, and apply directly to each employer without any intermediary step.
See All 69 Registered Nurse Case Manager Jobs in South Carolina
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