Specialty Sales Representative Jobs in California
Specialty Sales Representative jobs in California are among the most active in the country, concentrated in life sciences, medical devices, technology, and industrial distribution, with openings at every level from entry-level territory representatives through senior account executives and regional managers. The largest hiring volumes are in Los Angeles, San Francisco, and San Diego, where companies like Johnson and Johnson, Medtronic, and Salesforce maintain deep California footprints. The most sought-after specialties right now are pharmaceutical and biotech sales, medical device sales, and enterprise software solutions. Find a role that fits below and apply directly.
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Location: East Los Angeles, CA, United States
Date Updated: Sep 4, 2026
Job ID: 18078
Description
Arrowhead Pharmaceuticals is seeking experienced, high-performing, and driven Specialty Sales Representatives to join our expanding commercial organization. This is a unique opportunity to play a meaningful role in the launch and growth of our cardiometabolic portfolio, including Plozasiran (siRNA targeting APOC3), developed for patients with rare and high-need cardiovascular conditions such as Familial Chylomicronemia Syndrome (FCS) and Severe Hypertriglyceridemia (SHTG).
This role is critical to delivering launch excellence by driving prescriber activation, accelerating therapy adoption, and ensuring sustained utilization within complex healthcare environments. The Specialty Sales Representative will operate with strategic agility, strong clinical acumen, and disciplined execution to positively impact patient outcomes.
About Arrowhead Pharmaceuticals:
Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI and San Diego, CA. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
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Key Responsibilities:
Territory & Strategic Business Planning
- Develop and execute comprehensive, data-driven territory business plans aligned to brand strategy and launch objectives.
- Analyze territory data (prescribing trends, account potential, access landscape) to identify growth opportunities and prioritize high-value targets.
- Manage territory budget responsibly, including speaker programs and promotional initiatives.
- Consistently achieve or exceed sales goals and performance metrics.
Prescriber Activation & Clinical Engagement
- Deliver compelling, compliant, and clinically accurate product education within approved labeling.
- Articulate complex clinical data and value propositions tailored to cardiologists, lipid specialists, endocrinologists, and targeted PCPs.
- Differentiate Arrowhead therapies within a competitive and evolving cardiometabolic landscape.
- Execute speaker programs, educational events, and peer-to-peer engagements to drive awareness and adoption.
- Support appropriate patient identification and therapy initiation through thoughtful provider engagement.
Stakeholder & Account Management
- Build and sustain strong, trust-based relationships with healthcare professionals, office staff, and institutional stakeholders.
- Navigate complex health systems and coordinate effectively within IDNs in partnership with Key Account Managers.
- Identify access barriers and collaborate with Market Access and patient services to support pull-through.
- Maintain consistent, high-quality engagement and service across accounts to drive durable utilization.
Cross-Functional Collaboration
- Partner closely with Marketing, Medical Affairs, Market Access, Health IT, and Patient Services to align territory execution with enterprise strategy.
- Provide actionable field insights regarding market dynamics, competitive activity, and customer feedback.
Compliance & Operational Excellence
- Maintain full compliance with company policies, industry regulations, and promotional standards.
- Accurately document field activity and manage CRM reporting in a timely manner.
- Demonstrate disciplined execution, accountability, and ethical conduct in all engagements.
Travel & Engagement
- Represent Arrowhead at regional and national meetings, training programs, and key conferences (~30% travel required).
- Overnight travel may be necessary depending on territory geography.
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Qualifications:
Experience
- Bachelor's degree or equivalent experience and minimum 5 years of pharmaceutical sales experience required.
- Demonstrated success launching or expanding complex therapies requiring access navigation and clinical depth required.
- 3+ years in specialty, rare disease, or cardiovascular therapeutic areas strongly preferred.
- Experience working within integrated delivery networks (IDNs) or complex healthcare systems preferred.
Skills & Competencies
- Strong territory planning and account management capabilities with a data-driven mindset.
- Ability to interpret and communicate complex clinical data confidently and credibly.
- Excellent communication, presentation, and relationship-building skills.
- High level of business acumen and ability to identify strategic growth opportunities.
- Resilience, adaptability, and ability to thrive in a fast-paced launch environment.
- Proven track record of achieving or exceeding performance targets.
- Strong organizational skills and ability to manage competing priorities effectively.
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Compensation & Benefits:
- Competitive base salary: $160,000–$180,000 plus incentive compensation (20–30% target bonus).
- Equity (RSUs) and car allowance program.
- Comprehensive benefits package including health, dental, vision, and 401(k).
Ready to make a difference?
Join us in our mission to bring transformative RNAi therapies to patients with rare cardiovascular conditions. Apply now to be part of something extraordinary.
See All 15 Specialty Sales Representative Jobs in California
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Where California roles are concentrated, by current openings.
Specialty Sales Representative Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring


What California Employers Look For
The qualifications that appear most often in specialty sales representative jobs across California.
- Bachelor's degree in business, life sciences, or a related field required by most California employers
- Documented history of meeting or exceeding sales quotas in a defined territory
- Experience with CRM platforms such as Salesforce to manage pipelines and client records
- Familiarity with California's life sciences or technology sector and its key decision-makers
- Strong consultative selling skills with the ability to communicate complex product value clearly
- Valid California driver's license and willingness to travel within an assigned regional territory
Specialty Sales Representative Jobs in California: Frequently Asked Questions
How do you become a specialty sales representative in California?
Most specialty sales representative roles in California require a bachelor's degree, typically in business, biology, or a related field depending on the industry. Pharmaceutical and medical device sales roles often expect prior B2B or clinical sales experience, and some employers prefer candidates with specialized product training or manufacturer certifications. California does not require a state-issued license for most specialty sales roles, though medical device sales in surgical settings sometimes requires clinical credentialing through the relevant hospital system.
How much do specialty sales representatives make in California?
Specialty sales representatives in California earn a median of about $76,490 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $43,200 for the lowest 10% to over $152,760 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire specialty sales representatives in California?
Employers hiring specialty sales representatives in California right now include Taylor Strategy Partners, YourHire, and Amgen, based on current listings on Migrate Mate as of September 2026. California's density of life sciences headquarters, enterprise software firms, and medical device companies makes it one of the deepest specialty sales hiring markets in the country.
Which California cities have the most specialty sales representative jobs?
San Jose, Los Angeles, and Napa consistently lead California for specialty sales representative openings. Los Angeles and San Francisco draw the largest volumes due to their concentration of enterprise technology companies, health systems, and biotech firms, while San Diego's life sciences cluster anchors strong demand for pharmaceutical and medical device territory roles in that region.
Are there remote specialty sales representative jobs in California?
Yes, but they're less common than in purely desk-based fields. About 100% of specialty sales representative openings tied to California are remote or hybrid as of September 2026, reflecting the fact that most roles still require in-person client visits, product demonstrations, or hospital access. The parts of the role most likely to be remote are inside sales, account management for established accounts, and sales engineering support.
How can I get hired as a specialty sales representative in California with little or no experience?
The most realistic entry path is to start in an inside sales, sales development, or customer success role with a California-based tech or medical company, then transition into a specialty territory position. Large California employers such as Medtronic, Stryker, and enterprise software companies regularly hire associate sales representatives or sales development representatives with no prior specialty experience. Completing a manufacturer-sponsored product training program, earning a relevant industry certification, or demonstrating a strong academic background in life sciences or business gives candidates a measurable edge when applying to these associate-level openings.
Where can I find and apply to specialty sales representative jobs in California?
You can find and apply to specialty sales representative jobs in California on Migrate Mate, which lists current California openings across industries and experience levels. Search the listings to find roles that match your background, territory preference, and specialty area, then apply directly to the ones that fit.
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