Regional Sales Director Jobs in California
Regional Sales Director jobs in California are among the most active in the country, concentrated in technology, life sciences, enterprise software, and financial services, with openings that range from first-time directors stepping up from senior account management through experienced leaders overseeing multi-state territories. The heaviest hiring happens in the San Francisco Bay Area, Los Angeles, and San Diego, where anchor employers like Salesforce, Johnson & Johnson, and Wells Fargo consistently recruit regional sales directors to lead revenue teams. The most in-demand specialties are SaaS and cloud solutions sales, medtech and pharmaceutical sales, and financial products distribution. Find a role that fits below and apply directly.
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About Belite Bio
Belite Bio is a clinical-stage biopharmaceutical drug development company focused on advancing novel therapeutics targeting retinal degenerative eye diseases with significant unmet medical needs. Built on our proprietary Retinol Binding Protein 4 (RBP4) IP portfolio, our clinical pipeline includes Tinlarebant (LBS-008), an oral therapy currently in late-stage clinical trials (including the Phase 3 DRAGON and PHOENIX studies) for Stargardt disease (STGD1) and Geographic Atrophy (GA) in dry AMD.
At Belite Bio, we are dedicated to developing innovative solutions to treat untreatable conditions and prevent vision loss in patients worldwide. As an early-stage company, we value entrepreneurial thinking, collaboration, accountability and the ability to thrive in fast moving environments.
Position Overview
Key Responsibilities
- Manage and facilitate U.S. DS efforts to educate on genetic testing to successfully execute Belite Bio’s efforts in raising awareness of sponsored testing programs. Train and provide leadership to support DS team educational initiatives Assist in designing appropriate compensation structures and supporting DS team efforts to meet individual and team goals and expectations
Primary Responsibility #2: Cross-Functional Collaboration & Market Development
- Compliantly partner with cross-functional teams within Belite
- Assist Senior Director of U.S. Diagnostics in reporting requirements and other business needs as directed
- Contribute to ongoing development and implementation of the U.S. Diagnostic strategy
- Help DS’s identify potential Genetic Testing Key Opinion Leaders (KOLs) with educational needs pertaining to genetic testing programs, providing awareness to these HCPs
- Provide direct diagnostic field training and oversight, and assist with material creation
- Attend conferences to learn and understand diagnostic programs and testing
- Participate where compliant, in advocacy, outreach, and engagement with local organizations
- Support and assist with the delivery of high-quality educational and provide insights to inform strategy
- Educate HCPs and associated internal partner labs for seamless sponsored testing utilization
- Provide education for HCPs regarding resources for questions and follow up from the testing labs
- Provide expertise for IRD gene panels and best practices for testing utilization
Qualifications & Requirements
- BA/BS required; healthcare degree strongly preferred (MS, RN, PA, PharmD, PhD)
- Minimum 10+ years of pharma/biotech experience in sales, clinical/medical, or diagnostics
- Proven success working in high-performing, diverse teams
- Experience collaborating with KOLs, labs, and internal/external stakeholders
- Prior experience in rare or ultra-rare diseases with strong patient focus preferred
- Strong history of success leading teams to meet and exceed goals
- Diagnostic and scientific acumen
- Strategic thinking and operational capability
- Ability to succeed in matrixed environments
- Persistence, resilience, and achievement orientation
- Excellent communication and presentation skills
- Cross-functional capability and strong ethical standards
- Knowledge of ophthalmology genetics strongly preferred
- Extensive travel required
Equal Employment Opportunity & Accommodations
Belite Bio provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.
Belite Bio is committed to working with and providing reasonable accommodation to individuals with disabilities. If you need reasonable accommodation for any part of the application or interviewing process due to a medical condition or disability, please contact human resources to let us know the nature of your request.
Salary Disclosure
Pay Range: $230,000 to $255,000 USD (Salary offered will depend on candidate location, market rate adjustments, skills, and relevant experience).
Belite Bio provides a competitive total compensation package that includes base salary, annual incentive bonuses, equity participation, and a full benefit package (health, dental, vision, 401(k), and paid time off).
See All 195+ Regional Sales Director Jobs in California
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Find Regional Sales Director JobsRegional Sales Director Jobs by City in California
Where California roles are concentrated, by current openings.
Regional Sales Director Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring


Top Industries Hiring
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
- Manufacturing
- Distribution & Wholesale
- Energy
What California Employers Look For
The qualifications that appear most often in regional sales director jobs across California.
- Bachelor's degree in business, marketing, or a related field required by most California employers
- Five or more years of progressive B2B or enterprise sales experience with team leadership responsibility
- Demonstrated ability to build and manage quota-carrying sales teams across a defined geographic territory
- Proficiency with CRM platforms such as Salesforce, which is headquartered in California and widely adopted
- Strong forecasting and pipeline management skills aligned with California's data-driven sales culture
- Experience selling into California's dominant verticals, including technology, life sciences, or financial services
Regional Sales Director Jobs in California: Frequently Asked Questions
How do you become a regional sales director in California?
The most direct path is building a track of individual sales performance followed by team leadership experience, typically starting as an account executive or sales manager in California's technology, life sciences, or financial services sectors. California does not require a state-issued license to work as a regional sales director. Most employers look for a bachelor's degree and internal promotion from senior sales roles, and earning a Certified Sales Leadership Professional designation strengthens candidacy significantly.
How much do regional sales directors make in California?
Regional sales directors in California earn a median of about $134,910 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $64,430 for the lowest 10% to over $300,580 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire regional sales directors in California?
Employers hiring regional sales directors in California right now include FirstService Residential, Workday, and Belite Bio, based on current listings on Migrate Mate as of November 2026. California's concentration of Fortune 500 technology and life sciences headquarters means many of these roles oversee teams that sell across the Western United States.
Which California cities have the most regional sales director jobs?
San Francisco, Los Angeles, and San Diego have the most regional sales director openings in California. The Bay Area's density of enterprise software and cloud companies drives the largest share of postings, while Los Angeles draws heavily from media, fintech, and healthcare employers, and San Diego's medtech and biotech clusters generate consistent demand for directors with life sciences sales backgrounds.
Are there remote regional sales director jobs in California?
Yes, and more than most fields. About 66% of regional sales director openings tied to California are remote or hybrid as of November 2026, reflecting how much of the role centers on managing distributed teams and enterprise client relationships over video and phone. Strategic planning, pipeline review, and coaching calls translate well to remote work, though quarterly business reviews and key account meetings typically require in-person travel.
How can I get hired as a regional sales director in California with little or no experience?
The most realistic entry path is excelling as a senior account executive or team lead and then applying internally for director roles at large California-based employers such as Salesforce, Oracle, or Thermo Fisher, which run structured sales leadership development programs. Candidates who lack direct management experience can strengthen their profile by completing a frontline sales manager rotation, earning a Certified Sales Leadership Professional credential, or moving laterally from a sales operations or revenue enablement role where cross-functional influence demonstrates leadership readiness.
Where can I find and apply to regional sales director jobs in California?
You can find and apply to regional sales director jobs in California on Migrate Mate, which lists current California openings updated regularly. Find roles that fit your experience level, territory preference, and industry focus, then apply directly to each one.
See All 195+ Regional Sales Director Jobs in California
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